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Items: 1 to 50 of 213


The impact of white matter hyperintensities on speech perception.

Di Stadio A, Messineo D, Ralli M, Roccamatisi D, Musacchio A, Ricci G, Greco A.

Neurol Sci. 2020 Feb 24. doi: 10.1007/s10072-020-04295-8. [Epub ahead of print]


Workplace noise exposure and audiometric thresholds in dental technicians.

Musacchio A, Corrao CRN, Altissimi G, Scarpa A, Girolamo SD, Stadio AD, Greco A, Ralli M.

Int Tinnitus J. 2019 Sep 4;23(2):108-115. doi: 10.5935/0946-5448.20190019.


Molecular determinants of the Ska-Ndc80 interaction and their influence on microtubule tracking and force-coupling.

Huis In 't Veld PJ, Volkov VA, Stender ID, Musacchio A, Dogterom M.

Elife. 2019 Dec 5;8. pii: e49539. doi: 10.7554/eLife.49539.


Anti-Markovnikov Hydroamination of Unactivated Alkenes with Primary Alkyl Amines.

Miller DC, Ganley JM, Musacchio AJ, Sherwood TC, Ewing WR, Knowles RR.

J Am Chem Soc. 2019 Oct 23;141(42):16590-16594. doi: 10.1021/jacs.9b08746. Epub 2019 Oct 14.


Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing.

Pan D, Walstein K, Take A, Bier D, Kaiser N, Musacchio A.

Nat Commun. 2019 Sep 6;10(1):4046. doi: 10.1038/s41467-019-12019-6.


Assistance Dogs for Persons with Hearing Impairment: A Review.

Martellucci S, Belvisi V, Ralli M, Stadio AD, Musacchio A, Greco A, Gallo A, Vincentiis M, Attanasio G.

Int Tinnitus J. 2019 Jan 1;23(1):26-30. doi: 10.5935/0946-5448.20190005. Review.


Allylative Approaches to the Synthesis of Complex Guaianolide Sesquiterpenes from Apiaceae and Asteraceae.

Hu X, Musacchio AJ, Shen X, Tao Y, Maimone TJ.

J Am Chem Soc. 2019 Sep 18;141(37):14904-14915. doi: 10.1021/jacs.9b08001. Epub 2019 Sep 6.


Acetic acid bacteria encode two levansucrase types of different ecological relationship.

Jakob F, Quintero Y, Musacchio A, Estrada-de Los Santos P, Hernández L, Vogel RF.

Environ Microbiol. 2019 Nov;21(11):4151-4165. doi: 10.1111/1462-2920.14768. Epub 2019 Aug 29.


Electroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biology.

Alex A, Piano V, Polley S, Stuiver M, Voss S, Ciossani G, Overlack K, Voss B, Wohlgemuth S, Petrovic A, Wu Y, Selenko P, Musacchio A, Maffini S.

Elife. 2019 Jul 16;8. pii: e48287. doi: 10.7554/eLife.48287.


EU Nitrates Directive, from theory to practice: Environmental effectiveness and influence of regional governance on its performance.

Musacchio A, Re V, Mas-Pla J, Sacchi E.

Ambio. 2020 Feb;49(2):504-516. doi: 10.1007/s13280-019-01197-8. Epub 2019 May 21.


Engineered thermostable β-fructosidase from Thermotoga maritima with enhanced fructooligosaccharides synthesis.

Menéndez C, Martínez D, Pérez ER, Musacchio A, Ramírez R, López-Munguía A, Hernández L.

Enzyme Microb Technol. 2019 Jun;125:53-62. doi: 10.1016/j.enzmictec.2019.02.002. Epub 2019 Feb 6.


Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

Weith M, Seiler J, van den Boom J, Kracht M, Hülsmann J, Primorac I, Del Pino Garcia J, Kaschani F, Kaiser M, Musacchio A, Bollen M, Meyer H.

Mol Cell. 2018 Nov 15;72(4):766-777.e6. doi: 10.1016/j.molcel.2018.09.020. Epub 2018 Oct 18.


Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80.

Pesenti ME, Prumbaum D, Auckland P, Smith CM, Faesen AC, Petrovic A, Erent M, Maffini S, Pentakota S, Weir JR, Lin YC, Raunser S, McAinsh AD, Musacchio A.

Mol Cell. 2018 Sep 20;71(6):923-939.e10. doi: 10.1016/j.molcel.2018.07.038. Epub 2018 Aug 30.


Simplified Protocol for Cross-linking Mass Spectrometry Using the MS-Cleavable Cross-linker DSBU with Efficient Cross-link Identification.

Pan D, Brockmeyer A, Mueller F, Musacchio A, Bange T.

Anal Chem. 2018 Sep 18;90(18):10990-10999. doi: 10.1021/acs.analchem.8b02593. Epub 2018 Aug 29.


Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis.

Sacristan C, Ahmad MUD, Keller J, Fermie J, Groenewold V, Tromer E, Fish A, Melero R, Carazo JM, Klumperman J, Musacchio A, Perrakis A, Kops GJ.

Nat Cell Biol. 2018 Jul;20(7):800-810. doi: 10.1038/s41556-018-0130-3. Epub 2018 Jun 18.


The kinetochore proteins CENP-E and CENP-F directly and specifically interact with distinct BUB mitotic checkpoint Ser/Thr kinases.

Ciossani G, Overlack K, Petrovic A, Huis In 't Veld PJ, Koerner C, Wohlgemuth S, Maffini S, Musacchio A.

J Biol Chem. 2018 Jun 29;293(26):10084-10101. doi: 10.1074/jbc.RA118.003154. Epub 2018 May 10.


Multivalency of NDC80 in the outer kinetochore is essential to track shortening microtubules and generate forces.

Volkov VA, Huis In 't Veld PJ, Dogterom M, Musacchio A.

Elife. 2018 Apr 9;7. pii: e36764. doi: 10.7554/eLife.36764.


Decoding the centromeric nucleosome through CENP-N.

Pentakota S, Zhou K, Smith C, Maffini S, Petrovic A, Morgan GP, Weir JR, Vetter IR, Musacchio A, Luger K.

Elife. 2017 Dec 27;6. pii: e33442. doi: 10.7554/eLife.33442.


Fructooligosaccharides production by Schedonorus arundinaceus sucrose:sucrose 1-fructosyltransferase constitutively expressed to high levels in Pichia pastoris.

Hernández L, Menéndez C, Pérez ER, Martínez D, Alfonso D, Trujillo LE, Ramírez R, Sobrino A, Mazola Y, Musacchio A, Pimentel E.

J Biotechnol. 2018 Jan 20;266:59-71. doi: 10.1016/j.jbiotec.2017.12.008. Epub 2017 Dec 12.


BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling.

Overlack K, Bange T, Weissmann F, Faesen AC, Maffini S, Primorac I, Müller F, Peters JM, Musacchio A.

Curr Biol. 2017 Oct 9;27(19):2915-2927.e7. doi: 10.1016/j.cub.2017.08.033. Epub 2017 Sep 21.


The greatest kinetochore show on earth.

Vader G, Musacchio A.

EMBO Rep. 2017 Sep;18(9):1473-1475. doi: 10.15252/embr.201744541. Epub 2017 Jul 18. No abstract available.


Structure of the RZZ complex and molecular basis of its interaction with Spindly.

Mosalaganti S, Keller J, Altenfeld A, Winzker M, Rombaut P, Saur M, Petrovic A, Wehenkel A, Wohlgemuth S, Müller F, Maffini S, Bange T, Herzog F, Waldmann H, Raunser S, Musacchio A.

J Cell Biol. 2017 Apr 3;216(4):961-981. doi: 10.1083/jcb.201611060. Epub 2017 Mar 20.


Catalytic intermolecular hydroaminations of unactivated olefins with secondary alkyl amines.

Musacchio AJ, Lainhart BC, Zhang X, Naguib SG, Sherwood TC, Knowles RR.

Science. 2017 Feb 17;355(6326):727-730. doi: 10.1126/science.aal3010.


A Molecular View of Kinetochore Assembly and Function.

Musacchio A, Desai A.

Biology (Basel). 2017 Jan 24;6(1). pii: E5. doi: 10.3390/biology6010005. Review.


Basis of catalytic assembly of the mitotic checkpoint complex.

Faesen AC, Thanasoula M, Maffini S, Breit C, Müller F, van Gerwen S, Bange T, Musacchio A.

Nature. 2017 Feb 23;542(7642):498-502. doi: 10.1038/nature21384. Epub 2017 Jan 19.


CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading.

Pan D, Klare K, Petrovic A, Take A, Walstein K, Singh P, Rondelet A, Bird AW, Musacchio A.

Elife. 2017 Jan 6;6. pii: e23352. doi: 10.7554/eLife.23352.


Molecular basis of outer kinetochore assembly on CENP-T.

Huis In 't Veld PJ, Jeganathan S, Petrovic A, Singh P, John J, Krenn V, Weissmann F, Bange T, Musacchio A.

Elife. 2016 Dec 24;5. pii: e21007. doi: 10.7554/eLife.21007.


Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.

Petrovic A, Keller J, Liu Y, Overlack K, John J, Dimitrova YN, Jenni S, van Gerwen S, Stege P, Wohlgemuth S, Rombaut P, Herzog F, Harrison SC, Vetter IR, Musacchio A.

Cell. 2016 Nov 3;167(4):1028-1040.e15. doi: 10.1016/j.cell.2016.10.005. Epub 2016 Oct 27.


Insights from biochemical reconstitution into the architecture of human kinetochores.

Weir JR, Faesen AC, Klare K, Petrovic A, Basilico F, Fischböck J, Pentakota S, Keller J, Pesenti ME, Pan D, Vogt D, Wohlgemuth S, Herzog F, Musacchio A.

Nature. 2016 Sep 8;537(7619):249-253. doi: 10.1038/nature19333. Epub 2016 Aug 31.


Microtubules: 50 years on from the discovery of tubulin.

Borisy G, Heald R, Howard J, Janke C, Musacchio A, Nogales E.

Nat Rev Mol Cell Biol. 2016 Apr 22;17(5):322-8. doi: 10.1038/nrm.2016.45. Review.


Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin.

Friese A, Faesen AC, Huis in 't Veld PJ, Fischböck J, Prumbaum D, Petrovic A, Raunser S, Herzog F, Musacchio A.

Nat Commun. 2016 Apr 20;7:11407. doi: 10.1038/ncomms11407.


Progress in the structural and functional characterization of kinetochores.

Pesenti ME, Weir JR, Musacchio A.

Curr Opin Struct Biol. 2016 Apr;37:152-63. doi: 10.1016/ Epub 2016 Apr 1. Review.


Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster.

Liu Y, Petrovic A, Rombaut P, Mosalaganti S, Keller J, Raunser S, Herzog F, Musacchio A.

Open Biol. 2016 Feb;6(2):150236. doi: 10.1098/rsob.150236.


Adaptation of the STARR test for adult Italian population: A speech test for a realistic estimate in real-life listening conditions.

Dincer D'Alessandro H, Ballantyne D, De Seta E, Musacchio A, Mancini P.

Int J Audiol. 2016;55(4):262-7. doi: 10.3109/14992027.2015.1124296. Epub 2016 Jan 21.


Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint.

O'Connor A, Maffini S, Rainey MD, Kaczmarczyk A, Gaboriau D, Musacchio A, Santocanale C.

Biol Open. 2015 Dec 18;5(1):11-9. doi: 10.1242/bio.014969.


Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.

Breit C, Bange T, Petrovic A, Weir JR, Müller F, Vogt D, Musacchio A.

PLoS One. 2015 Dec 10;10(12):e0144673. doi: 10.1371/journal.pone.0144673. eCollection 2015.


The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling.

Krenn V, Musacchio A.

Front Oncol. 2015 Oct 16;5:225. doi: 10.3389/fonc.2015.00225. eCollection 2015. Review.


The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics.

Musacchio A.

Curr Biol. 2015 Oct 19;25(20):R1002-18. doi: 10.1016/j.cub.2015.08.051. Review. Erratum in: Curr Biol. 2015 Nov 16;25(22):3017.


A comparative molecular dynamics study of thermophilic and mesophilic β-fructosidase enzymes.

Mazola Y, Guirola O, Palomares S, Chinea G, Menéndez C, Hernández L, Musacchio A.

J Mol Model. 2015 Sep;21(9):228. doi: 10.1007/s00894-015-2772-4. Epub 2015 Aug 13.


CENP-C is a blueprint for constitutive centromere-associated network assembly within human kinetochores.

Klare K, Weir JR, Basilico F, Zimniak T, Massimiliano L, Ludwigs N, Herzog F, Musacchio A.

J Cell Biol. 2015 Jul 6;210(1):11-22. doi: 10.1083/jcb.201412028. Epub 2015 Jun 29.


Closing the Mad2 cycle.

Musacchio A.

Elife. 2015 May 22;4. doi: 10.7554/eLife.08283.


Complex assembly, crystallization and preliminary X-ray crystallographic analysis of the human Rod-Zwilch-ZW10 (RZZ) complex.

Altenfeld A, Wohlgemuth S, Wehenkel A, Vetter IR, Musacchio A.

Acta Crystallogr F Struct Biol Commun. 2015 Apr;71(Pt 4):438-42. doi: 10.1107/S2053230X15004343. Epub 2015 Mar 20.


HJURP involvement in de novo CenH3(CENP-A) and CENP-C recruitment.

Tachiwana H, Müller S, Blümer J, Klare K, Musacchio A, Almouzni G.

Cell Rep. 2015 Apr 7;11(1):22-32. doi: 10.1016/j.celrep.2015.03.013. Epub 2015 Apr 2.


The (phospho) needle in the (MELT) Haystack.

Faesen AC, Musacchio A.

Mol Cell. 2015 Mar 5;57(5):765-766. doi: 10.1016/j.molcel.2015.02.026.


Adequate formal language performance in unilateral cochlear implanted children: is it indicative of complete recovery in all linguistic domains? Insights from referential communication.

Mancini P, Dincer D'Alessandro H, Guerzoni L, Cuda D, Ruoppolo G, Musacchio A, Di Mario A, De Seta E, Bosco E, Nicastri M.

Int J Pediatr Otorhinolaryngol. 2015 Apr;79(4):598-604. doi: 10.1016/j.ijporl.2015.02.003. Epub 2015 Feb 11.


DNA-Directed Assembly of Capture Tools for Constitutional Studies of Large Protein Complexes.

Meyer R, Faesen A, Vogel K, Jeganathan S, Musacchio A, Niemeyer CM.

Small. 2015 Jun 10;11(22):2669-74. doi: 10.1002/smll.201403544. Epub 2015 Feb 3.


A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint.

Overlack K, Primorac I, Vleugel M, Krenn V, Maffini S, Hoffmann I, Kops GJ, Musacchio A.

Elife. 2015 Jan 22;4:e05269. doi: 10.7554/eLife.05269.


HORMA domains at the heart of meiotic chromosome dynamics.

Vader G, Musacchio A.

Dev Cell. 2014 Nov 24;31(4):389-91. doi: 10.1016/j.devcel.2014.11.009. Epub 2014 Nov 24.


Inhibitor-3 ensures bipolar mitotic spindle attachment by limiting association of SDS22 with kinetochore-bound protein phosphatase-1.

Eiteneuer A, Seiler J, Weith M, Beullens M, Lesage B, Krenn V, Musacchio A, Bollen M, Meyer H.

EMBO J. 2014 Nov 18;33(22):2704-20. doi: 10.15252/embj.201489054. Epub 2014 Oct 8.


Catalytic olefin hydroamination with aminium radical cations: a photoredox method for direct C-N bond formation.

Musacchio AJ, Nguyen LQ, Beard GH, Knowles RR.

J Am Chem Soc. 2014 Sep 3;136(35):12217-20. doi: 10.1021/ja5056774. Epub 2014 Aug 19.


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