Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 44

1.

Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism.

Krah NM, Narayanan SM, Yugawa DE, Straley JA, Wright CVE, MacDonald RJ, Murtaugh LC.

Dev Cell. 2019 Sep 23;50(6):744-754.e4. doi: 10.1016/j.devcel.2019.07.012. Epub 2019 Aug 15.

PMID:
31422917
2.

An inflammatory transcriptional switch.

Murtaugh LC, MacDonald RJ.

Nature. 2018 Feb 22;554(7693):470-472. doi: 10.1038/d41586-018-01262-4. No abstract available.

PMID:
29469130
3.

Differentiation and Inflammation: 'Best Enemies' in Gastrointestinal Carcinogenesis.

Krah NM, Murtaugh LC.

Trends Cancer. 2016 Dec;2(12):723-735. doi: 10.1016/j.trecan.2016.11.005. Review.

4.

Genomic analyses identify molecular subtypes of pancreatic cancer.

Bailey P, Chang DK, Nones K, Johns AL, Patch AM, Gingras MC, Miller DK, Christ AN, Bruxner TJ, Quinn MC, Nourse C, Murtaugh LC, Harliwong I, Idrisoglu S, Manning S, Nourbakhsh E, Wani S, Fink L, Holmes O, Chin V, Anderson MJ, Kazakoff S, Leonard C, Newell F, Waddell N, Wood S, Xu Q, Wilson PJ, Cloonan N, Kassahn KS, Taylor D, Quek K, Robertson A, Pantano L, Mincarelli L, Sanchez LN, Evers L, Wu J, Pinese M, Cowley MJ, Jones MD, Colvin EK, Nagrial AM, Humphrey ES, Chantrill LA, Mawson A, Humphris J, Chou A, Pajic M, Scarlett CJ, Pinho AV, Giry-Laterriere M, Rooman I, Samra JS, Kench JG, Lovell JA, Merrett ND, Toon CW, Epari K, Nguyen NQ, Barbour A, Zeps N, Moran-Jones K, Jamieson NB, Graham JS, Duthie F, Oien K, Hair J, Grützmann R, Maitra A, Iacobuzio-Donahue CA, Wolfgang CL, Morgan RA, Lawlor RT, Corbo V, Bassi C, Rusev B, Capelli P, Salvia R, Tortora G, Mukhopadhyay D, Petersen GM; Australian Pancreatic Cancer Genome Initiative, Munzy DM, Fisher WE, Karim SA, Eshleman JR, Hruban RH, Pilarsky C, Morton JP, Sansom OJ, Scarpa A, Musgrove EA, Bailey UM, Hofmann O, Sutherland RL, Wheeler DA, Gill AJ, Gibbs RA, Pearson JV, Waddell N, Biankin AV, Grimmond SM.

Nature. 2016 Mar 3;531(7592):47-52. doi: 10.1038/nature16965. Epub 2016 Feb 24.

PMID:
26909576
5.

The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.

Krah NM, De La O JP, Swift GH, Hoang CQ, Willet SG, Chen Pan F, Cash GM, Bronner MP, Wright CV, MacDonald RJ, Murtaugh LC.

Elife. 2015 Jul 7;4. doi: 10.7554/eLife.07125.

6.

Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis.

Bankhead EJ, Colasanto MP, Dyorich KM, Jamrich M, Murtaugh LC, Fuhrmann S.

Am J Pathol. 2015 Jan;185(1):197-213. doi: 10.1016/j.ajpath.2014.09.002. Epub 2014 Nov 3.

7.

Regeneration and repair of the exocrine pancreas.

Murtaugh LC, Keefe MD.

Annu Rev Physiol. 2015;77:229-49. doi: 10.1146/annurev-physiol-021014-071727. Epub 2014 Oct 24. Review.

8.

Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning.

Baumgartner BK, Cash G, Hansen H, Ostler S, Murtaugh LC.

Dev Biol. 2014 Jul 1;391(1):89-98. doi: 10.1016/j.ydbio.2014.03.019. Epub 2014 Apr 8.

9.

Wnt secretion from epithelial cells and subepithelial myofibroblasts is not required in the mouse intestinal stem cell niche in vivo.

San Roman AK, Jayewickreme CD, Murtaugh LC, Shivdasani RA.

Stem Cell Reports. 2014 Jan 30;2(2):127-34. doi: 10.1016/j.stemcr.2013.12.012. eCollection 2014 Feb 11.

10.

Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration.

Veniaminova NA, Vagnozzi AN, Kopinke D, Do TT, Murtaugh LC, Maillard I, Dlugosz AA, Reiter JF, Wong SY.

Development. 2013 Dec;140(24):4870-80. doi: 10.1242/dev.101725. Epub 2013 Nov 6.

11.

Pathogenesis of pancreatic cancer: lessons from animal models.

Murtaugh LC.

Toxicol Pathol. 2014 Jan;42(1):217-28. doi: 10.1177/0192623313508250. Epub 2013 Oct 31. Review.

12.

Lhx2 balances progenitor maintenance with neurogenic output and promotes competence state progression in the developing retina.

Gordon PJ, Yun S, Clark AM, Monuki ES, Murtaugh LC, Levine EM.

J Neurosci. 2013 Jul 24;33(30):12197-207. doi: 10.1523/JNEUROSCI.1494-13.2013.

13.

Putting GWAS to the functional test: NR5A2 and pancreatic cancer risk.

Murtaugh LC.

Gut. 2014 Apr;63(4):535-6. doi: 10.1136/gutjnl-2013-305030. Epub 2013 Jun 12. No abstract available.

PMID:
23759730
14.

Wnt signaling regulates postembryonic hypothalamic progenitor differentiation.

Wang X, Kopinke D, Lin J, McPherson AD, Duncan RN, Otsuna H, Moro E, Hoshijima K, Grunwald DJ, Argenton F, Chien CB, Murtaugh LC, Dorsky RI.

Dev Cell. 2012 Sep 11;23(3):624-36. doi: 10.1016/j.devcel.2012.07.012.

15.

β-catenin is selectively required for the expansion and regeneration of mature pancreatic acinar cells in mice.

Keefe MD, Wang H, De La O JP, Khan A, Firpo MA, Murtaugh LC.

Dis Model Mech. 2012 Jul;5(4):503-14. doi: 10.1242/dmm.007799. Epub 2012 Jan 19.

16.

Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas.

Kopinke D, Brailsford M, Pan FC, Magnuson MA, Wright CV, Murtaugh LC.

Dev Biol. 2012 Feb 1;362(1):57-64. doi: 10.1016/j.ydbio.2011.11.010. Epub 2011 Nov 29.

17.

Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome.

Barrott JJ, Cash GM, Smith AP, Barrow JR, Murtaugh LC.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12752-7. doi: 10.1073/pnas.1006437108. Epub 2011 Jul 18.

18.

Stem cells and β cells: the same, but different?

Murtaugh LC.

Cell Stem Cell. 2011 Mar 4;8(3):244-5. doi: 10.1016/j.stem.2011.02.010.

19.

Understanding endoderm development: more than just a series of tubes.

Murtaugh LC, Wells JM.

Dev Dyn. 2011 Mar;240(3):461-2. doi: 10.1002/dvdy.22587. No abstract available.

20.

Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas.

Kopinke D, Brailsford M, Shea JE, Leavitt R, Scaife CL, Murtaugh LC.

Development. 2011 Feb;138(3):431-41. doi: 10.1242/dev.053843.

21.

University of North Carolina's experience with state medical assistance teams.

Strickler J, Murtaugh L, Hoffman R.

J Trauma Nurs. 2010 Jul-Sep;17(3):167-8. doi: 10.1097/JTN.0b013e3181f5228b.

PMID:
20838167
22.

Pancreatic stem cells.

Murtaugh LC, Kopinke D.

StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.
2008 Jul 11.

23.

Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas.

Kopinke D, Murtaugh LC.

BMC Dev Biol. 2010 Apr 8;10:38. doi: 10.1186/1471-213X-10-38.

24.

Lhx2 links the intrinsic and extrinsic factors that control optic cup formation.

Yun S, Saijoh Y, Hirokawa KE, Kopinke D, Murtaugh LC, Monuki ES, Levine EM.

Development. 2009 Dec;136(23):3895-906. doi: 10.1242/dev.041202.

25.

Notch and Kras in pancreatic cancer: at the crossroads of mutation, differentiation and signaling.

De La O JP, Murtaugh LC.

Cell Cycle. 2009 Jun 15;8(12):1860-4. Epub 2009 Jun 15.

26.

Notch signaling: where pancreatic cancer and differentiation meet?

De La O JP, Murtaugh LC.

Gastroenterology. 2009 May;136(5):1499-502. doi: 10.1053/j.gastro.2009.03.022. Epub 2009 Mar 25. No abstract available.

PMID:
19327730
27.

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia.

De La O JP, Emerson LL, Goodman JL, Froebe SC, Illum BE, Curtis AB, Murtaugh LC.

Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18907-12. doi: 10.1073/pnas.0810111105. Epub 2008 Nov 21.

28.
29.

A case of mistaken identity? Nonductal origins of pancreatic "ductal" cancers.

Murtaugh LC, Leach SD.

Cancer Cell. 2007 Mar;11(3):211-3.

30.

Pancreas and beta-cell development: from the actual to the possible.

Murtaugh LC.

Development. 2007 Feb;134(3):427-38. Epub 2006 Dec 21. Review.

31.

Nkx3.2/Bapx1 acts as a negative regulator of chondrocyte maturation.

Provot S, Kempf H, Murtaugh LC, Chung UI, Kim DW, Chyung J, Kronenberg HM, Lassar AB.

Development. 2006 Feb;133(4):651-62. Epub 2006 Jan 18.

32.

Beta-catenin is essential for pancreatic acinar but not islet development.

Murtaugh LC, Law AC, Dor Y, Melton DA.

Development. 2005 Nov;132(21):4663-74. Epub 2005 Sep 28.

33.

Direct regulation of intestinal fate by Notch.

Stanger BZ, Datar R, Murtaugh LC, Melton DA.

Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12443-8. Epub 2005 Aug 17.

34.

Notch signaling controls multiple steps of pancreatic differentiation.

Murtaugh LC, Stanger BZ, Kwan KM, Melton DA.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14920-5. Epub 2003 Dec 1.

35.

Genes, signals, and lineages in pancreas development.

Murtaugh LC, Melton DA.

Annu Rev Cell Dev Biol. 2003;19:71-89. Review.

PMID:
14570564
36.

Role of VEGF-A in vascularization of pancreatic islets.

Lammert E, Gu G, McLaughlin M, Brown D, Brekken R, Murtaugh LC, Gerber HP, Ferrara N, Melton DA.

Curr Biol. 2003 Jun 17;13(12):1070-4.

37.

Shh establishes an Nkx3.2/Sox9 autoregulatory loop that is maintained by BMP signals to induce somitic chondrogenesis.

Zeng L, Kempf H, Murtaugh LC, Sato ME, Lassar AB.

Genes Dev. 2002 Aug 1;16(15):1990-2005.

38.
39.

Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments.

Schweitzer R, Chyung JH, Murtaugh LC, Brent AE, Rosen V, Olson EN, Lassar A, Tabin CJ.

Development. 2001 Oct;128(19):3855-66.

40.

Gizzard formation and the role of Bapx1.

Nielsen C, Murtaugh LC, Chyung JC, Lassar A, Roberts DJ.

Dev Biol. 2001 Mar 1;231(1):164-74.

41.
42.

Analysis of Hox gene expression in the chick limb bud.

Nelson CE, Morgan BA, Burke AC, Laufer E, DiMambro E, Murtaugh LC, Gonzales E, Tessarollo L, Parada LF, Tabin C.

Development. 1996 May;122(5):1449-66.

43.
44.

Twenty-one polymorphic markers from human chromosome 12 for integration of genetic and physical maps.

LeBlanc-Straceski JM, Montgomery KT, Kissel H, Murtaugh L, Tsai P, Ward DC, Krauter KS, Kucherlapati R.

Genomics. 1994 Jan 15;19(2):341-9.

PMID:
8188264

Supplemental Content

Loading ...
Support Center