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Items: 1 to 50 of 210

1.

Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy.

Bertero A, Fields PA, Smith AST, Leonard A, Beussman K, Sniadecki NJ, Kim DH, Tse HF, Pabon L, Shendure J, Noble WS, Murry CE.

J Cell Biol. 2019 Aug 8. pii: jcb.201902117. doi: 10.1083/jcb.201902117. [Epub ahead of print]

PMID:
31395619
2.

Learn from Your Elders: Developmental Biology Lessons to Guide Maturation of Stem Cell-Derived Cardiomyocytes.

Marchianò S, Bertero A, Murry CE.

Pediatr Cardiol. 2019 Aug 6. doi: 10.1007/s00246-019-02165-5. [Epub ahead of print]

PMID:
31388700
3.

Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration.

Bargehr J, Ong LP, Colzani M, Davaapil H, Hofsteen P, Bhandari S, Gambardella L, Le Novère N, Iyer D, Sampaziotis F, Weinberger F, Bertero A, Leonard A, Bernard WG, Martinson A, Figg N, Regnier M, Bennett MR, Murry CE, Sinha S.

Nat Biotechnol. 2019 Aug;37(8):895-906. doi: 10.1038/s41587-019-0197-9. Epub 2019 Aug 2.

PMID:
31375810
4.

The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy.

Salvarani N, Crasto S, Miragoli M, Bertero A, Paulis M, Kunderfranco P, Serio S, Forni A, Lucarelli C, Dal Ferro M, Larcher V, Sinagra G, Vezzoni P, Murry CE, Faggian G, Condorelli G, Di Pasquale E.

Nat Commun. 2019 May 22;10(1):2267. doi: 10.1038/s41467-019-09929-w.

5.

Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human induced pluripotent stem cells.

Pioner JM, Guan X, Klaiman JM, Racca AW, Pabon L, Muskheli V, Macadangdang J, Ferrantini C, Hoopmann MR, Moritz RL, Kim DH, Tesi C, Poggesi C, Murry CE, Childers MK, Mack DL, Regnier M.

Cardiovasc Res. 2019 May 2. pii: cvz109. doi: 10.1093/cvr/cvz109. [Epub ahead of print]

PMID:
31049579
6.

Lost in the fire.

Marchianò S, Murry CE.

Science. 2019 Apr 12;364(6436):123-124. doi: 10.1126/science.aax1006. No abstract available.

PMID:
30975873
7.

Dynamics of genome reorganization during human cardiogenesis reveal an RBM20-dependent splicing factory.

Bertero A, Fields PA, Ramani V, Bonora G, Yardimci GG, Reinecke H, Pabon L, Noble WS, Shendure J, Murry CE.

Nat Commun. 2019 Apr 4;10(1):1538. doi: 10.1038/s41467-019-09483-5.

8.

Regenerating the field of cardiovascular cell therapy.

Chien KR, Frisén J, Fritsche-Danielson R, Melton DA, Murry CE, Weissman IL.

Nat Biotechnol. 2019 Mar;37(3):232-237. doi: 10.1038/s41587-019-0042-1. Epub 2019 Feb 18. Review.

PMID:
30778231
9.

Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts.

Redd MA, Zeinstra N, Qin W, Wei W, Martinson A, Wang Y, Wang RK, Murry CE, Zheng Y.

Nat Commun. 2019 Feb 4;10(1):584. doi: 10.1038/s41467-019-08388-7.

10.

Novel Adult-Onset Systolic Cardiomyopathy Due to MYH7 E848G Mutation in Patient-Derived Induced Pluripotent Stem Cells.

Yang KC, Breitbart A, De Lange WJ, Hofsteen P, Futakuchi-Tsuchida A, Xu J, Schopf C, Razumova MV, Jiao A, Boucek R, Pabon L, Reinecke H, Kim DH, Ralphe JC, Regnier M, Murry CE.

JACC Basic Transl Sci. 2018 Dec 31;3(6):728-740. doi: 10.1016/j.jacbts.2018.08.008. eCollection 2018 Dec.

11.

Evidence for Minimal Cardiogenic Potential of Stem Cell Antigen 1-Positive Cells in the Adult Mouse Heart.

Neidig LE, Weinberger F, Palpant NJ, Mignone J, Martinson AM, Sorensen DW, Bender I, Nemoto N, Reinecke H, Pabon L, Molkentin JD, Murry CE, van Berlo JH.

Circulation. 2018 Dec 18;138(25):2960-2962. doi: 10.1161/CIRCULATIONAHA.118.035273. No abstract available.

12.

Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation.

Friedman CE, Nguyen Q, Lukowski SW, Helfer A, Chiu HS, Miklas J, Levy S, Suo S, Han JJ, Osteil P, Peng G, Jing N, Baillie GJ, Senabouth A, Christ AN, Bruxner TJ, Murry CE, Wong ES, Ding J, Wang Y, Hudson J, Ruohola-Baker H, Bar-Joseph Z, Tam PPL, Powell JE, Palpant NJ.

Cell Stem Cell. 2018 Oct 4;23(4):586-598.e8. doi: 10.1016/j.stem.2018.09.009.

PMID:
30290179
13.

Human Organ-Specific Endothelial Cell Heterogeneity.

Marcu R, Choi YJ, Xue J, Fortin CL, Wang Y, Nagao RJ, Xu J, MacDonald JW, Bammler TK, Murry CE, Muczynski K, Stevens KR, Himmelfarb J, Schwartz SM, Zheng Y.

iScience. 2018 Jun 29;4:20-35. doi: 10.1016/j.isci.2018.05.003. Epub 2018 May 9.

14.

Hallmarks of cardiac regeneration.

Bertero A, Murry CE.

Nat Rev Cardiol. 2018 Oct;15(10):579-580. doi: 10.1038/s41569-018-0079-8. No abstract available.

15.

Erratum: Human embryonic stem cell-derived cardiomyocytes restore function in infarcted hearts of non-human primates.

Liu YW, Chen B, Yang X, Fugate JA, Kalucki FA, Futakuchi-Tsuchida A, Couture L, Vogel KW, Astley CA, Baldessari A, Ogle J, Don CW, Steinberg ZL, Seslar SP, Tuck SA, Tsuchida H, Naumova AV, Dupras SK, Lyu MS, Lee J, Hailey DW, Reinecke H, Pabon L, Fryer BH, MacLellan WR, Thies RS, Murry CE.

Nat Biotechnol. 2018 Sep 6;36(9):899. doi: 10.1038/nbt0918-899a. No abstract available.

PMID:
30188532
16.

Genetic Lineage Tracing of Sca-1+ Cells Reveals Endothelial but Not Myogenic Contribution to the Murine Heart.

Vagnozzi RJ, Sargent MA, Lin SJ, Palpant NJ, Murry CE, Molkentin JD.

Circulation. 2018 Dec 18;138(25):2931-2939. doi: 10.1161/CIRCULATIONAHA.118.035210. Erratum in: Circulation. 2018 Oct 9;138(15):e424.

PMID:
29991486
17.

Human embryonic stem cell-derived cardiomyocytes restore function in infarcted hearts of non-human primates.

Liu YW, Chen B, Yang X, Fugate JA, Kalucki FA, Futakuchi-Tsuchida A, Couture L, Vogel KW, Astley CA, Baldessari A, Ogle J, Don CW, Steinberg ZL, Seslar SP, Tuck SA, Tsuchida H, Naumova AV, Dupras SK, Lyu MS, Lee J, Hailey DW, Reinecke H, Pabon L, Fryer BH, MacLellan WR, Thies RS, Murry CE.

Nat Biotechnol. 2018 Aug;36(7):597-605. doi: 10.1038/nbt.4162. Epub 2018 Jul 2. Erratum in: Nat Biotechnol. 2018 Sep 6;36(9):899.

18.

ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells.

Hofsteen P, Robitaille AM, Strash N, Palpant N, Moon RT, Pabon L, Murry CE.

iScience. 2018 Apr 27;2:88-100. doi: 10.1016/j.isci.2018.03.010.

19.

The Challenges of First-in-Human Stem Cell Clinical Trials: What Does This Mean for Ethics and Institutional Review Boards?

Barker RA, Carpenter MK, Forbes S, Goldman SA, Jamieson C, Murry CE, Takahashi J, Weir G.

Stem Cell Reports. 2018 May 8;10(5):1429-1431. doi: 10.1016/j.stemcr.2018.04.010. Review.

20.

Afterload promotes maturation of human induced pluripotent stem cell derived cardiomyocytes in engineered heart tissues.

Leonard A, Bertero A, Powers JD, Beussman KM, Bhandari S, Regnier M, Murry CE, Sniadecki NJ.

J Mol Cell Cardiol. 2018 May;118:147-158. doi: 10.1016/j.yjmcc.2018.03.016. Epub 2018 Mar 28.

21.

Human Pluripotent Stem Cell-Derived Engineered Tissues: Clinical Considerations.

Stevens KR, Murry CE.

Cell Stem Cell. 2018 Mar 1;22(3):294-297. doi: 10.1016/j.stem.2018.01.015.

22.

Regulation of skeletal myotube formation and alignment by nanotopographically controlled cell-secreted extracellular matrix.

Jiao A, Moerk CT, Penland N, Perla M, Kim J, Smith AST, Murry CE, Kim DH.

J Biomed Mater Res A. 2018 Jun;106(6):1543-1551. doi: 10.1002/jbm.a.36351. Epub 2018 Feb 19.

23.

Sustained miRNA release regenerates the heart.

Mitzelfelt KA, Murry CE.

Nat Biomed Eng. 2017 Dec;1(12):931-933. doi: 10.1038/s41551-017-0171-0. No abstract available.

PMID:
31015704
24.

Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis.

Palpant NJ, Wang Y, Hadland B, Zaunbrecher RJ, Redd M, Jones D, Pabon L, Jain R, Epstein J, Ruzzo WL, Zheng Y, Bernstein I, Margolin A, Murry CE.

Cell Rep. 2017 Aug 15;20(7):1597-1608. doi: 10.1016/j.celrep.2017.07.067.

25.

Cardiomyocyte Regeneration: A Consensus Statement.

Eschenhagen T, Bolli R, Braun T, Field LJ, Fleischmann BK, Frisén J, Giacca M, Hare JM, Houser S, Lee RT, Marbán E, Martin JF, Molkentin JD, Murry CE, Riley PR, Ruiz-Lozano P, Sadek HA, Sussman MA, Hill JA.

Circulation. 2017 Aug 15;136(7):680-686. doi: 10.1161/CIRCULATIONAHA.117.029343. Epub 2017 Jul 6. Review. No abstract available.

26.

Micro- and nano-patterned conductive graphene-PEG hybrid scaffolds for cardiac tissue engineering.

Smith AST, Yoo H, Yi H, Ahn EH, Lee JH, Shao G, Nagornyak E, Laflamme MA, Murry CE, Kim DH.

Chem Commun (Camb). 2017 Jun 29;53(53):7412-7415. doi: 10.1039/c7cc01988b.

27.

Translation of Cardiac Myosin Activation with 2-deoxy-ATP to Treat Heart Failure via an Experimental Ribonucleotide Reductase-Based Gene Therapy.

Thomson KS, Odom GL, Murry CE, Mahairas GG, Moussavi-Harami F, Teichman SL, Chen X, Hauschka SD, Chamberlain JS, Regnier M.

JACC Basic Transl Sci. 2016 Dec;1(7):666-679. doi: 10.1016/j.jacbts.2016.07.006.

28.

One Stride Forward: Maturation and Scalable Production of Engineered Human Myocardium.

Yang X, Murry CE.

Circulation. 2017 May 9;135(19):1848-1850. doi: 10.1161/CIRCULATIONAHA.117.024751. No abstract available.

29.

In Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts.

Kadota S, Pabon L, Reinecke H, Murry CE.

Stem Cell Reports. 2017 Feb 14;8(2):278-289. doi: 10.1016/j.stemcr.2016.10.009. Epub 2017 Jan 5.

30.

Erratum to: Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development.

Szabo L, Morey R, Palpant NJ, Wang PL, Afari N, Jiang C, Parast MM, Murry CE, Laurent LC, Salzman J.

Genome Biol. 2016 Dec 19;17(1):263. No abstract available.

31.

Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells.

Palpant NJ, Pabon L, Friedman CE, Roberts M, Hadland B, Zaunbrecher RJ, Bernstein I, Zheng Y, Murry CE.

Nat Protoc. 2017 Jan;12(1):15-31. doi: 10.1038/nprot.2016.153. Epub 2016 Dec 1.

32.

Depth-resolved 3D visualization of coronary microvasculature with optical microangiography.

Qin W, Roberts MA, Qi X, Murry CE, Zheng Y, Wang RK.

Phys Med Biol. 2016 Nov 7;61(21):7536-7550. Epub 2016 Oct 7.

33.

Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac Tissue.

Ruan JL, Tulloch NL, Razumova MV, Saiget M, Muskheli V, Pabon L, Reinecke H, Regnier M, Murry CE.

Circulation. 2016 Nov 15;134(20):1557-1567. Epub 2016 Oct 13.

34.

Real-Time Force and Frequency Analysis of Engineered Human Heart Tissue Derived from Induced Pluripotent Stem Cells Using Magnetic Sensing.

Bielawski KS, Leonard A, Bhandari S, Murry CE, Sniadecki NJ.

Tissue Eng Part C Methods. 2016 Oct;22(10):932-940. doi: 10.1089/ten.TEC.2016.0257. Epub 2016 Sep 28.

35.

Prosurvival Factors Improve Functional Engraftment of Myogenically Converted Dermal Cells into Dystrophic Skeletal Muscle.

Muir LA, Murry CE, Chamberlain JS.

Stem Cells Dev. 2016 Oct;25(20):1559-1569. Epub 2016 Sep 7.

36.

Distilling complexity to advance cardiac tissue engineering.

Ogle BM, Bursac N, Domian I, Huang NF, Menasché P, Murry CE, Pruitt B, Radisic M, Wu JC, Wu SM, Zhang J, Zimmermann WH, Vunjak-Novakovic G.

Sci Transl Med. 2016 Jun 8;8(342):342ps13. doi: 10.1126/scitranslmed.aad2304. Review.

37.

Policy: Global standards for stem-cell research.

Kimmelman J, Hyun I, Benvenisty N, Caulfield T, Heslop HE, Murry CE, Sipp D, Studer L, Sugarman J, Daley GQ.

Nature. 2016 May 19;533(7603):311-3. doi: 10.1038/533311a. No abstract available.

PMID:
27193661
38.

Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines.

Daley GQ, Hyun I, Apperley JF, Barker RA, Benvenisty N, Bredenoord AL, Breuer CK, Caulfield T, Cedars MI, Frey-Vasconcells J, Heslop HE, Jin Y, Lee RT, McCabe C, Munsie M, Murry CE, Piantadosi S, Rao M, Rooke HM, Sipp D, Studer L, Sugarman J, Takahashi M, Zimmerman M, Kimmelman J.

Stem Cell Reports. 2016 Jun 14;6(6):787-797. doi: 10.1016/j.stemcr.2016.05.001. Epub 2016 May 12.

39.

New ISSCR guidelines: clinical translation of stem cell research.

Kimmelman J, Heslop HE, Sugarman J, Studer L, Benvenisty N, Caulfield T, Hyun I, Murry CE, Sipp D, Daley GQ.

Lancet. 2016 May 14;387(10032):1979-81. No abstract available.

PMID:
27179752
40.

SCIENTIFIC COMMUNITY. Confronting stem cell hype.

Caulfield T, Sipp D, Murry CE, Daley GQ, Kimmelman J.

Science. 2016 May 13;352(6287):776-7. doi: 10.1126/science.aaf4620. Epub 2016 May 12. No abstract available.

PMID:
27174977
41.

Isolation and Mechanical Measurements of Myofibrils from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Pioner JM, Racca AW, Klaiman JM, Yang KC, Guan X, Pabon L, Muskheli V, Zaunbrecher R, Macadangdang J, Jeong MY, Mack DL, Childers MK, Kim DH, Tesi C, Poggesi C, Murry CE, Regnier M.

Stem Cell Reports. 2016 Jun 14;6(6):885-896. doi: 10.1016/j.stemcr.2016.04.006. Epub 2016 May 5.

42.

Imprecision Medicine: A One-Size-Fits-Many Approach for Muscle Dystrophy.

Breitbart A, Murry CE.

Cell Stem Cell. 2016 Apr 7;18(4):423-4. doi: 10.1016/j.stem.2016.03.004.

43.

Stromal Cells in Dense Collagen Promote Cardiomyocyte and Microvascular Patterning in Engineered Human Heart Tissue.

Roberts MA, Tran D, Coulombe KL, Razumova M, Regnier M, Murry CE, Zheng Y.

Tissue Eng Part A. 2016 Apr;22(7-8):633-44. doi: 10.1089/ten.TEA.2015.0482. Epub 2016 Mar 31.

44.

Nanotopography-Induced Structural Anisotropy and Sarcomere Development in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells.

Carson D, Hnilova M, Yang X, Nemeth CL, Tsui JH, Smith AS, Jiao A, Regnier M, Murry CE, Tamerler C, Kim DH.

ACS Appl Mater Interfaces. 2016 Aug 31;8(34):21923-32. doi: 10.1021/acsami.5b11671. Epub 2016 Feb 11.

45.

Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-catenin signaling.

Hofsteen P, Robitaille AM, Chapman DP, Moon RT, Murry CE.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1002-7. doi: 10.1073/pnas.1523930113. Epub 2016 Jan 11.

46.

Comparison of Human Embryonic Stem Cell-Derived Cardiomyocytes, Cardiovascular Progenitors, and Bone Marrow Mononuclear Cells for Cardiac Repair.

Fernandes S, Chong JJH, Paige SL, Iwata M, Torok-Storb B, Keller G, Reinecke H, Murry CE.

Stem Cell Reports. 2015 Nov 10;5(5):753-762. doi: 10.1016/j.stemcr.2015.09.011.

47.

The advancement of human pluripotent stem cell-derived therapies into the clinic.

Thies RS, Murry CE.

Development. 2015 Oct 15;142(20):3614. doi: 10.1242/dev.131250.

48.

The advancement of human pluripotent stem cell-derived therapies into the clinic.

Thies RS, Murry CE.

Development. 2015 Sep 15;142(18):3077-84. doi: 10.1242/dev.126482. Erratum in: Development. 2015 Oct 15;142(20):3614.

49.

AAV6-mediated Cardiac-specific Overexpression of Ribonucleotide Reductase Enhances Myocardial Contractility.

Kolwicz SC Jr, Odom GL, Nowakowski SG, Moussavi-Harami F, Chen X, Reinecke H, Hauschka SD, Murry CE, Mahairas GG, Regnier M.

Mol Ther. 2016 Feb;24(2):240-250. doi: 10.1038/mt.2015.176. Epub 2015 Sep 21.

50.

Defined MicroRNAs Induce Aspects of Maturation in Mouse and Human Embryonic-Stem-Cell-Derived Cardiomyocytes.

Lee DS, Chen JH, Lundy DJ, Liu CH, Hwang SM, Pabon L, Shieh RC, Chen CC, Wu SN, Yan YT, Lee ST, Chiang PM, Chien S, Murry CE, Hsieh PC.

Cell Rep. 2015 Sep 29;12(12):1960-7. doi: 10.1016/j.celrep.2015.08.042. Epub 2015 Sep 10.

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