Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 158


Molecular organization of mammalian meiotic chromosome axis revealed by expansion STORM microscopy.

Xu H, Tong Z, Ye Q, Sun T, Hong Z, Zhang L, Bortnick A, Cho S, Beuzer P, Axelrod J, Hu Q, Wang M, Evans SM, Murre C, Lu LF, Sun S, Corbett KD, Cang H.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18423-18428. doi: 10.1073/pnas.1902440116. Epub 2019 Aug 23.


Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions.

Khanna N, Zhang Y, Lucas JS, Dudko OK, Murre C.

Nat Commun. 2019 Jun 24;10(1):2771. doi: 10.1038/s41467-019-10628-9.


CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis.

Arends T, Dege C, Bortnick A, Danhorn T, Knapp JR, Jia H, Harmacek L, Fleenor CJ, Straign D, Walton K, Leach SM, Feeney AJ, Murre C, O'Connor BP, Hagman JR.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):10927-10936. doi: 10.1073/pnas.1821301116. Epub 2019 May 13.


Helix-loop-helix proteins and the advent of cellular diversity: 30 years of discovery.

Murre C.

Genes Dev. 2019 Jan 1;33(1-2):6-25. doi: 10.1101/gad.320663.118. Review.


A B-Cell-Specific Enhancer Orchestrates Nuclear Architecture to Generate a Diverse Antigen Receptor Repertoire.

Barajas-Mora EM, Kleiman E, Xu J, Carrico NC, Lu H, Oltz EM, Murre C, Feeney AJ.

Mol Cell. 2019 Jan 3;73(1):48-60.e5. doi: 10.1016/j.molcel.2018.10.013. Epub 2018 Nov 15.


'Big bang' of B-cell development revealed.

Murre C.

Genes Dev. 2018 Jan 15;32(2):93-95. doi: 10.1101/gad.311357.118. Review.


Id Proteins Suppress E2A-Driven Invariant Natural Killer T Cell Development prior to TCR Selection.

Roy S, Moore AJ, Love C, Reddy A, Rajagopalan D, Dave SS, Li L, Murre C, Zhuang Y.

Front Immunol. 2018 Jan 24;9:42. doi: 10.3389/fimmu.2018.00042. eCollection 2018.


mTECs Aire on the side of caution.

Bortnick A, Murre C.

Nat Immunol. 2018 Feb;19(2):100-101. doi: 10.1038/s41590-017-0033-7. No abstract available.


Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate.

Isoda T, Moore AJ, He Z, Chandra V, Aida M, Denholtz M, Piet van Hamburg J, Fisch KM, Chang AN, Fahl SP, Wiest DL, Murre C.

Cell. 2017 Sep 21;171(1):103-119.e18. doi: 10.1016/j.cell.2017.09.001.


CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs.

Chisolm DA, Savic D, Moore AJ, Ballesteros-Tato A, León B, Crossman DK, Murre C, Myers RM, Weinmann AS.

Immunity. 2017 Aug 15;47(2):251-267.e7. doi: 10.1016/j.immuni.2017.07.015.


The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development.

Miyazaki M, Miyazaki K, Chen K, Jin Y, Turner J, Moore AJ, Saito R, Yoshida K, Ogawa S, Rodewald HR, Lin YC, Kawamoto H, Murre C.

Immunity. 2017 May 16;46(5):818-834.e4. doi: 10.1016/j.immuni.2017.04.022.


Comprehensive characterization of neutrophil genome topology.

Zhu Y, Gong K, Denholtz M, Chandra V, Kamps MP, Alber F, Murre C.

Genes Dev. 2017 Jan 15;31(2):141-153. doi: 10.1101/gad.293910.116. Epub 2017 Feb 6.


Id3 Orchestrates Germinal Center B Cell Development.

Chen S, Miyazaki M, Chandra V, Fisch KM, Chang AN, Murre C.

Mol Cell Biol. 2016 Sep 26;36(20):2543-52. doi: 10.1128/MCB.00150-16. Print 2016 Oct 15.


A Common Mechanism that Underpins Antibody Diversification.

Murre C.

Cell. 2015 Nov 19;163(5):1055-1056. doi: 10.1016/j.cell.2015.10.075.


Cellular and chromatin dynamics of antibody-secreting plasma cells.

Bortnick A, Murre C.

Wiley Interdiscip Rev Dev Biol. 2016 Mar-Apr;5(2):136-49. doi: 10.1002/wdev.213. Epub 2015 Oct 21. Review.



Murre C.

Adv Immunol. 2015;128:xi-xii. doi: 10.1016/S0065-2776(15)00069-3. No abstract available.


New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors.

Benner C, Isoda T, Murre C.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12776-81. doi: 10.1073/pnas.1512995112. Epub 2015 Sep 28.


Nuclear positioning rather than contraction controls ordered rearrangements of immunoglobulin loci.

Rother MB, Palstra RJ, Jhunjhunwala S, van Kester KA, van IJcken WF, Hendriks RW, van Dongen JJ, Murre C, van Zelm MC.

Nucleic Acids Res. 2016 Jan 8;44(1):175-86. doi: 10.1093/nar/gkv928. Epub 2015 Sep 17.


AID targeting: old mysteries and new challenges.

Chandra V, Bortnick A, Murre C.

Trends Immunol. 2015 Sep;36(9):527-35. doi: 10.1016/ Epub 2015 Aug 4. Review.


The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth.

Bossen C, Murre CS, Chang AN, Mansson R, Rodewald HR, Murre C.

Nat Immunol. 2015 Jul;16(7):775-84. doi: 10.1038/ni.3170. Epub 2015 May 18.


The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.

Miyazaki M, Miyazaki K, Chen S, Chandra V, Wagatsuma K, Agata Y, Rodewald HR, Saito R, Chang AN, Varki N, Kawamoto H, Murre C.

Genes Dev. 2015 Feb 15;29(4):409-25. doi: 10.1101/gad.255331.114.


Ensuring an equal playing field for antigen receptor loci variable regions.

Murre C.

J Exp Med. 2015 Jan 12;212(1):2. doi: 10.1084/jem.2121insight1. No abstract available.


B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.

Qian J, Wang Q, Dose M, Pruett N, Kieffer-Kwon KR, Resch W, Liang G, Tang Z, Mathé E, Benner C, Dubois W, Nelson S, Vian L, Oliveira TY, Jankovic M, Hakim O, Gazumyan A, Pavri R, Awasthi P, Song B, Liu G, Chen L, Zhu S, Feigenbaum L, Staudt L, Murre C, Ruan Y, Robbiani DF, Pan-Hammarström Q, Nussenzweig MC, Casellas R.

Cell. 2014 Dec 18;159(7):1524-37. doi: 10.1016/j.cell.2014.11.013. Epub 2014 Dec 4.


3D trajectories adopted by coding and regulatory DNA elements: first-passage times for genomic interactions.

Lucas JS, Zhang Y, Dudko OK, Murre C.

Cell. 2014 Jul 17;158(2):339-352. doi: 10.1016/j.cell.2014.05.036. Epub 2014 Jul 3.


Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease.

Miyazaki M, Miyazaki K, Chen S, Itoi M, Miller M, Lu LF, Varki N, Chang AN, Broide DH, Murre C.

Nat Immunol. 2014 Aug;15(8):767-76. doi: 10.1038/ni.2928. Epub 2014 Jun 29.


The establishment of B versus T cell identity.

Miyazaki K, Miyazaki M, Murre C.

Trends Immunol. 2014 May;35(5):205-10. doi: 10.1016/ Epub 2014 Mar 26. Review.


A HESitant decision for T cells.

Bortnick A, Murre C.

Nat Immunol. 2013 Dec;14(12):1209-10. doi: 10.1038/ni.2765. No abstract available.


The epigenetics of early lymphocyte development.

Murre C.

Cold Spring Harb Symp Quant Biol. 2013;78:43-9. doi: 10.1101/sqb.2013.78.020149. Epub 2013 Oct 3.


Boosting lymphocyte production.

Murre C.

Immunity. 2013 Jun 27;38(6):1081-3. doi: 10.1016/j.immuni.2013.06.002.


Nuclear location and the control of developmental progression.

Lin YC, Murre C.

Curr Opin Genet Dev. 2013 Apr;23(2):104-8. doi: 10.1016/j.gde.2012.11.010. Epub 2012 Dec 19. Review.


Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate.

Mansson R, Welinder E, Åhsberg J, Lin YC, Benner C, Glass CK, Lucas JS, Sigvardsson M, Murre C.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21028-33. doi: 10.1073/pnas.1211427109. Epub 2012 Dec 4.


β-Selection-induced proliferation is required for αβ T cell differentiation.

Kreslavsky T, Gleimer M, Miyazaki M, Choi Y, Gagnon E, Murre C, Sicinski P, von Boehmer H.

Immunity. 2012 Nov 16;37(5):840-53. doi: 10.1016/j.immuni.2012.08.020.


Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate.

Lin YC, Benner C, Mansson R, Heinz S, Miyazaki K, Miyazaki M, Chandra V, Bossen C, Glass CK, Murre C.

Nat Immunol. 2012 Dec;13(12):1196-204. doi: 10.1038/ni.2432. Epub 2012 Oct 14.


E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus.

Sakamoto S, Wakae K, Anzai Y, Murai K, Tamaki N, Miyazaki M, Miyazaki K, Romanow WJ, Ikawa T, Kitamura D, Yanagihara I, Minato N, Murre C, Agata Y.

J Immunol. 2012 Jun 1;188(11):5547-60. doi: 10.4049/jimmunol.1002346. Epub 2012 Apr 27.


Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47.

Teachenor R, Beck K, Wright LY, Shen Z, Briggs SP, Murre C.

Mol Cell Biol. 2012 May;32(9):1671-82. doi: 10.1128/MCB.06452-11. Epub 2012 Feb 21.


Chromatin topology and the regulation of antigen receptor assembly.

Bossen C, Mansson R, Murre C.

Annu Rev Immunol. 2012;30:337-56. doi: 10.1146/annurev-immunol-020711-075003. Epub 2012 Jan 3. Review.


The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets.

Yang CY, Best JA, Knell J, Yang E, Sheridan AD, Jesionek AK, Li HS, Rivera RR, Lind KC, D'Cruz LM, Watowich SS, Murre C, Goldrath AW.

Nat Immunol. 2011 Nov 6;12(12):1221-9. doi: 10.1038/ni.2158.


The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor.

Welinder E, Mansson R, Mercer EM, Bryder D, Sigvardsson M, Murre C.

Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17402-7. doi: 10.1073/pnas.1111766108. Epub 2011 Oct 4.


Factors and networks that underpin early hematopoiesis.

Mercer EM, Lin YC, Murre C.

Semin Immunol. 2011 Oct;23(5):317-25. doi: 10.1016/j.smim.2011.08.004. Epub 2011 Sep 18. Review.


CTCF-binding elements mediate control of V(D)J recombination.

Guo C, Yoon HS, Franklin A, Jain S, Ebert A, Cheng HL, Hansen E, Despo O, Bossen C, Vettermann C, Bates JG, Richards N, Myers D, Patel H, Gallagher M, Schlissel MS, Murre C, Busslinger M, Giallourakis CC, Alt FW.

Nature. 2011 Sep 11;477(7365):424-30. doi: 10.1038/nature10495.


Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors.

Mercer EM, Lin YC, Benner C, Jhunjhunwala S, Dutkowski J, Flores M, Sigvardsson M, Ideker T, Glass CK, Murre C.

Immunity. 2011 Sep 23;35(3):413-25. doi: 10.1016/j.immuni.2011.06.013. Epub 2011 Sep 8.


The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells.

Miyazaki M, Rivera RR, Miyazaki K, Lin YC, Agata Y, Murre C.

Nat Immunol. 2011 Aug 21;12(10):992-1001. doi: 10.1038/ni.2086. Erratum in: Nat Immunol. 2013 Apr;14(4):413.


CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells.

Degner SC, Verma-Gaur J, Wong TP, Bossen C, Iverson GM, Torkamani A, Vettermann C, Lin YC, Ju Z, Schulz D, Murre CS, Birshtein BK, Schork NJ, Schlissel MS, Riblet R, Murre C, Feeney AJ.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9566-71. doi: 10.1073/pnas.1019391108. Epub 2011 May 23.


Ldb1, a new guardian of hematopoietic stem cell maintenance.

Welinder E, Murre C.

Nat Immunol. 2011 Feb;12(2):113-4. doi: 10.1038/ni0211-113. No abstract available.


Transcription and recombination factories: common features?

Lucas JS, Bossen C, Murre C.

Curr Opin Cell Biol. 2011 Jun;23(3):318-24. doi: 10.1016/ Epub 2010 Dec 17. Review.


Global approaches to identify novel participants that modulate intestinal epithelial cell development.

Murre C.

Dev Cell. 2010 Nov 16;19(5):647-8. doi: 10.1016/j.devcel.2010.10.018.


A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate.

Lin YC, Jhunjhunwala S, Benner C, Heinz S, Welinder E, Mansson R, Sigvardsson M, Hagman J, Espinoza CA, Dutkowski J, Ideker T, Glass CK, Murre C.

Nat Immunol. 2010 Jul;11(7):635-43. doi: 10.1038/ni.1891. Epub 2010 Jun 13.


Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities.

Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK.

Mol Cell. 2010 May 28;38(4):576-89. doi: 10.1016/j.molcel.2010.05.004.


Current Opinion in Immunology. Editorial overview.

Rothenberg EV, Murre C.

Curr Opin Immunol. 2010 Apr;22(2):145-7. doi: 10.1016/j.coi.2010.03.002. Epub 2010 Mar 19. No abstract available.


Developmental trajectories in early hematopoiesis.

Murre C.

Genes Dev. 2009 Oct 15;23(20):2366-70. doi: 10.1101/gad.1861709.

Supplemental Content

Support Center