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The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells.

Duarte RRR, Bachtel ND, Côtel MC, Lee SH, Selvackadunco S, Watson IA, Hovsepian GA, Troakes C, Breen GD, Nixon DF, Murray RM, Bray NJ, Eleftherianos I, Vernon AC, Powell TR, Srivastava DP.

Biol Psychiatry. 2019 Mar 30. pii: S0006-3223(19)31148-5. doi: 10.1016/j.biopsych.2019.03.977. [Epub ahead of print]


Hospitalisation and length of hospital stay following first-episode psychosis: systematic review and meta-analysis of longitudinal studies.

Ajnakina O, Stubbs B, Francis E, Gaughran F, David AS, Murray RM, Lally J.

Psychol Med. 2019 May 6:1-11. doi: 10.1017/S0033291719000904. [Epub ahead of print]


Verbal Fluency Is Affected by Altered Brain Lateralization in Adults Who Were Born Very Preterm.

Tseng CJ, Froudist-Walsh S, Kroll J, Karolis V, Brittain PJ, Palamin N, Clifton H, Counsell SJ, Williams SCR, Murray RM, Nosarti C.

eNeuro. 2019 Apr 15;6(2). pii: ENEURO.0274-18.2018. doi: 10.1523/ENEURO.0274-18.2018. eCollection 2019 Mar-Apr.


The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study.

Di Forti M, Quattrone D, Freeman TP, Tripoli G, Gayer-Anderson C, Quigley H, Rodriguez V, Jongsma HE, Ferraro L, La Cascia C, La Barbera D, Tarricone I, Berardi D, Szöke A, Arango C, Tortelli A, Velthorst E, Bernardo M, Del-Ben CM, Menezes PR, Selten JP, Jones PB, Kirkbride JB, Rutten BP, de Haan L, Sham PC, van Os J, Lewis CM, Lynskey M, Morgan C, Murray RM; EU-GEI WP2 Group.

Lancet Psychiatry. 2019 May;6(5):427-436. doi: 10.1016/S2215-0366(19)30048-3. Epub 2019 Mar 19.


Using Machine Learning and Structural Neuroimaging to Detect First Episode Psychosis: Reconsidering the Evidence.

Vieira S, Gong QY, Pinaya WHL, Scarpazza C, Tognin S, Crespo-Facorro B, Tordesillas-Gutierrez D, Ortiz-García V, Setien-Suero E, Scheepers FE, Van Haren NEM, Marques TR, Murray RM, David A, Dazzan P, McGuire P, Mechelli A.

Schizophr Bull. 2019 Feb 27. pii: sby189. doi: 10.1093/schbul/sby189. [Epub ahead of print]


Construction of Incoherent Feedforward Loop Circuits in a Cell-Free System and in Cells.

Guo S, Murray RM.

ACS Synth Biol. 2019 Mar 15;8(3):606-610. doi: 10.1021/acssynbio.8b00493. Epub 2019 Mar 6.


Association of a Schizophrenia-Risk Nonsynonymous Variant With Putamen Volume in Adolescents: A Voxelwise and Genome-Wide Association Study.

Luo Q, Chen Q, Wang W, Desrivières S, Quinlan EB, Jia T, Macare C, Robert GH, Cui J, Guedj M, Palaniyappan L, Kherif F, Banaschewski T, Bokde ALW, Büchel C, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Artiges E, Paillère-Martinot ML, Nees F, Orfanos DP, Poustka L, Fröhner JH, Smolka MN, Walter H, Whelan R, Callicott JH, Mattay VS, Pausova Z, Dartigues JF, Tzourio C, Crivello F, Berman KF, Li F, Paus T, Weinberger DR, Murray RM, Schumann G, Feng J; IMAGEN consortium.

JAMA Psychiatry. 2019 Jan 16. doi: 10.1001/jamapsychiatry.2018.4126. [Epub ahead of print]


'At risk mental state' clinics for psychosis - an idea whose time has come - and gone!

Ajnakina O, David AS, Murray RM.

Psychol Med. 2018 Dec 26:1-6. doi: 10.1017/S0033291718003859. [Epub ahead of print]


The Representativeness of Participants With Severe Mental Illness in a Psychosocial Clinical Trial.

Lally J, Watkins R, Nash S, Shetty H, Gardner-Sood P, Smith S, Murray RM, Gaughran F.

Front Psychiatry. 2018 Dec 4;9:654. doi: 10.3389/fpsyt.2018.00654. eCollection 2018.


Assessing cross-national invariance of the Community Assessment of Psychic Experiences (CAPE).

Pignon B, Peyre H, Ferchiou A, van Os J, Rutten BPF, Murray RM, Morgan C, Leboyer M, Schürhoff F, Szöke A; EU-GEI WP2 Group Author.

Psychol Med. 2018 Dec 5:1-8. doi: 10.1017/S0033291718003574. [Epub ahead of print]


Jumping to conclusions at first onset of psychosis predicts longer admissions, more compulsory admissions and police involvement over the next 4 years: the GAP study.

Rodriguez V, Ajnakina O, Stilo SA, Mondelli V, Marques TR, Trotta A, Quattrone D, Gardner-Sood P, Colizzi M, Wiffen BD, Dazzan P, Di Forti M, Falcone MA, David AS, Murray RM.

Psychol Med. 2018 Nov 5:1-11. doi: 10.1017/S0033291718003197. [Epub ahead of print]


Neuropsychological function at first episode in treatment-resistant psychosis: findings from the ÆSOP-10 study.

Kravariti E, Demjaha A, Zanelli J, Ibrahim F, Wise C, MacCabe JH, Reichenberg A, Pilecka I, Morgan K, Fearon P, Morgan C, Doody GA, Donoghue K, Jones PB, Kaçar AŞ, Dazzan P, Lappin J, Murray RM.

Psychol Med. 2018 Oct 23:1-11. doi: 10.1017/S0033291718002957. [Epub ahead of print]


Transdiagnostic dimensions of psychopathology at first episode psychosis: findings from the multinational EU-GEI study.

Quattrone D, Di Forti M, Gayer-Anderson C, Ferraro L, Jongsma HE, Tripoli G, La Cascia C, La Barbera D, Tarricone I, Berardi D, Szöke A, Arango C, Lasalvia A, Tortelli A, Llorca PM, de Haan L, Velthorst E, Bobes J, Bernardo M, Sanjuán J, Santos JL, Arrojo M, Del-Ben CM, Menezes PR, Selten JP; EU-GEI WP2 Group, Jones PB, Kirkbride JB, Richards AL, O'Donovan MC, Sham PC, Vassos E, Rutten BP, van Os J, Morgan C, Lewis CM, Murray RM, Reininghaus U.

Psychol Med. 2019 Jun;49(8):1378-1391. doi: 10.1017/S0033291718002131. Epub 2018 Oct 4.


Insight and risk of suicidal behaviour in two first-episode psychosis cohorts: Effects of previous suicide attempts and depression.

Lopez-Morinigo JD, Di Forti M, Ajnakina O, Wiffen BD, Morgan K, Doody GA, Jones PB, Ayesa-Arriola R, Canal-Rivero M, Crespo-Facorro B, Murray RM, Dazzan P, Morgan C, Dutta R, David AS.

Schizophr Res. 2019 Feb;204:80-89. doi: 10.1016/j.schres.2018.09.016. Epub 2018 Sep 22.


Metabolic-inflammatory status as predictor of clinical outcome at 1-year follow-up in patients with first episode psychosis.

Nettis MA, Pergola G, Kolliakou A, O'Connor J, Bonaccorso S, David A, Gaughran F, Di Forti M, Murray RM, Marques TR, Blasi G, Bertolino A, Pariante CM, Dazzan P, Mondelli V.

Psychoneuroendocrinology. 2019 Jan;99:145-153. doi: 10.1016/j.psyneuen.2018.09.005. Epub 2018 Sep 8.


Vitamin D and clinical symptoms in First Episode Psychosis (FEP): A prospective cohort study.

Lally J, Ajnakina O, Singh N, Gardner-Sood P, Stubbs B, Stringer D, Di Forti M, David AS, Smith S, Murray RM, Howes OD, Gaughran F.

Schizophr Res. 2019 Feb;204:381-388. doi: 10.1016/j.schres.2018.08.011. Epub 2018 Aug 25.


Different types of childhood adversity and 5-year outcomes in a longitudinal cohort of first-episode psychosis patients.

Ajnakina O, Trotta A, Forti MD, Stilo SA, Kolliakou A, Gardner-Sood P, Lopez-Morinigo J, Gaughran F, David AS, Dazzan P, Pariante C, Mondelli V, Murray RM, Fisher HL.

Psychiatry Res. 2018 Nov;269:199-206. doi: 10.1016/j.psychres.2018.08.054. Epub 2018 Aug 17.


Associations Between Non-neurological Autoimmune Disorders and Psychosis: A Meta-analysis.

Cullen AE, Holmes S, Pollak TA, Blackman G, Joyce DW, Kempton MJ, Murray RM, McGuire P, Mondelli V.

Biol Psychiatry. 2019 Jan 1;85(1):35-48. doi: 10.1016/j.biopsych.2018.06.016. Epub 2018 Jun 28.


Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders.

Calafato MS, Thygesen JH, Ranlund S, Zartaloudi E, Cahn W, Crespo-Facorro B, Díez-Revuelta Á, Di Forti M; Genetic Risk and Outcome of Psychosis (GROUP) consortium, Hall MH, Iyegbe C, Jablensky A, Kahn R, Kalaydjieva L, Kravariti E, Lin K, McDonald C, McIntosh AM, McQuillin A, Picchioni M, Rujescu D, Shaikh M, Toulopoulou T, Os JV, Vassos E, Walshe M, Powell J, Lewis CM, Murray RM, Bramon E.

Br J Psychiatry. 2018 Sep;213(3):535-541. doi: 10.1192/bjp.2018.89.


On-chip membrane protein cell-free expression enables development of a direct binding assay: A curious case of potassium channel KcsA-Kv1.3.

Vaish A, Guo S, Murray RM, Grandsard PJ, Chen Q.

Anal Biochem. 2018 Sep 1;556:70-77. doi: 10.1016/j.ab.2018.06.018. Epub 2018 Jun 21.


Is the grass greener for those at risk of psychosis?

Murray RM.

Schizophr Res. 2018 Nov;201:35-36. doi: 10.1016/j.schres.2018.04.041. Epub 2018 Jun 18. No abstract available.


Increasing expectations and knowledge require a more subtle use of prophylactic antipsychotics.

Murray RM, Di Forti M.

World Psychiatry. 2018 Jun;17(2):161-162. doi: 10.1002/wps.20517. No abstract available.


Cortical thickness correlates of minor neurological signs in patients with first episode psychosis.

Ciufolini S, Ponteduro MF, Reis-Marques T, Taylor H, Mondelli V, Pariante CM, Bonaccorso S, Chan R, Simmons A, David A, Di Forti M, Murray RM, Dazzan P.

Schizophr Res. 2018 Oct;200:104-111. doi: 10.1016/j.schres.2018.05.005. Epub 2018 May 18.


Cortisol awakening response is decreased in patients with first-episode psychosis and increased in healthy controls with a history of severe childhood abuse.

Ciufolini S, Gayer-Anderson C, Fisher HL, Marques TR, Taylor H, Di Forti M, Zunszain P, Morgan C, Murray RM, Pariante CM, Dazzan P, Mondelli V.

Schizophr Res. 2019 Mar;205:38-44. doi: 10.1016/j.schres.2018.05.002. Epub 2018 May 24.


Single Day Construction of Multigene Circuits with 3G Assembly.

Halleran AD, Swaminathan A, Murray RM.

ACS Synth Biol. 2018 May 18;7(5):1477-1480. doi: 10.1021/acssynbio.8b00060. Epub 2018 May 7.


Interaction between childhood adversity and functional polymorphisms in the dopamine pathway on first-episode psychosis.

Trotta A, Iyegbe C, Yiend J, Dazzan P, David AS, Pariante C, Mondelli V, Colizzi M, Murray RM, Di Forti M, Fisher HL.

Schizophr Res. 2019 Mar;205:51-57. doi: 10.1016/j.schres.2018.04.010. Epub 2018 Apr 10.


The antipsychotic landscape: dopamine and beyond.

Morrison PD, Murray RM.

Ther Adv Psychopharmacol. 2018 Apr;8(4):127-135. doi: 10.1177/2045125317752915. Epub 2018 Jan 23. Review.


Early sustained recovery following first episode psychosis: Evidence from the AESOP10 follow-up study.

Lappin JM, Heslin M, Lomas B, Jones PB, Doody GA, Reininghaus UA, Croudace T, Craig T, Fearon P, Murray RM, Dazzan P, Morgan C.

Schizophr Res. 2018 Sep;199:341-345. doi: 10.1016/j.schres.2018.03.014. Epub 2018 Mar 20.


Effects of cannabis use on body mass, fasting glucose and lipids during the first 12 months of treatment in schizophrenia spectrum disorders.

Scheffler F, Kilian S, Chiliza B, Asmal L, Phahladira L, du Plessis S, Kidd M, Murray RM, Di Forti M, Seedat S, Emsley R.

Schizophr Res. 2018 Sep;199:90-95. doi: 10.1016/j.schres.2018.02.050. Epub 2018 Mar 6.


Validation of an algorithm-based definition of treatment resistance in patients with schizophrenia.

Ajnakina O, Horsdal HT, Lally J, MacCabe JH, Murray RM, Gasse C, Wimberley T.

Schizophr Res. 2018 Feb 19. pii: S0920-9964(18)30091-4. doi: 10.1016/j.schres.2018.02.017. [Epub ahead of print]


What causes psychosis? An umbrella review of risk and protective factors.

Radua J, Ramella-Cravaro V, Ioannidis JPA, Reichenberg A, Phiphopthatsanee N, Amir T, Yenn Thoo H, Oliver D, Davies C, Morgan C, McGuire P, Murray RM, Fusar-Poli P.

World Psychiatry. 2018 Feb;17(1):49-66. doi: 10.1002/wps.20490.


A dimensional approach to assessing psychiatric risk in adults born very preterm.

Kroll J, Froudist-Walsh S, Brittain PJ, Tseng CJ, Karolis V, Murray RM, Nosarti C.

Psychol Med. 2018 Jul;48(10):1738-1744. doi: 10.1017/S0033291717003804. Epub 2018 Jan 19.


Treated Incidence of Psychotic Disorders in the Multinational EU-GEI Study.

Jongsma HE, Gayer-Anderson C, Lasalvia A, Quattrone D, Mulè A, Szöke A, Selten JP, Turner C, Arango C, Tarricone I, Berardi D, Tortelli A, Llorca PM, de Haan L, Bobes J, Bernardo M, Sanjuán J, Santos JL, Arrojo M, Del-Ben CM, Menezes PR, Velthorst E, Murray RM, Rutten BP, Jones PB, van Os J, Morgan C, Kirkbride JB; European Network of National Schizophrenia Networks Studying Gene-Environment Interactions Work Package 2 (EU-GEI WP2) Group.

JAMA Psychiatry. 2018 Jan 1;75(1):36-46. doi: 10.1001/jamapsychiatry.2017.3554.


The effect of perinatal brain injury on dopaminergic function and hippocampal volume in adult life.

Froudist-Walsh S, Bloomfield MA, Veronese M, Kroll J, Karolis VR, Jauhar S, Bonoldi I, McGuire PK, Kapur S, Murray RM, Nosarti C, Howes O.

Elife. 2017 Nov 28;6. pii: e29088. doi: 10.7554/eLife.29088.


Perinatal Asphyxia in Rat Alters Expression of Novel Schizophrenia Risk Genes.

Paparelli A, Iwata K, Wakuda T, Iyegbe C, Murray RM, Takei N.

Front Mol Neurosci. 2017 Oct 27;10:341. doi: 10.3389/fnmol.2017.00341. eCollection 2017.


Cell-Free and In Vivo Characterization of Lux, Las, and Rpa Quorum Activation Systems in E. coli.

Halleran AD, Murray RM.

ACS Synth Biol. 2018 Feb 16;7(2):752-755. doi: 10.1021/acssynbio.7b00376. Epub 2017 Nov 28.


Development of multivariable models to predict change in Body Mass Index within a clinical trial population of psychotic individuals.

Harrison RNS, Gaughran F, Murray RM, Lee SH, Cano JP, Dempster D, Curtis CJ, Dima D, Patel H, de Jong S, Breen G.

Sci Rep. 2017 Nov 7;7(1):14738. doi: 10.1038/s41598-017-15137-7.


Associations between psychosis endophenotypes across brain functional, structural, and cognitive domains.

Blakey R, Ranlund S, Zartaloudi E, Cahn W, Calafato S, Colizzi M, Crespo-Facorro B, Daniel C, Díez-Revuelta Á, Di Forti M; GROUP, Iyegbe C, Jablensky A, Jones R, Hall MH, Kahn R, Kalaydjieva L, Kravariti E, Lin K, McDonald C, McIntosh AM, Picchioni M, Powell J, Presman A, Rujescu D, Schulze K, Shaikh M, Thygesen JH, Toulopoulou T, Van Haren N, Van Os J, Walshe M, Murray RM, Bramon E.

Psychol Med. 2018 Jun;48(8):1325-1340. doi: 10.1017/S0033291717002860. Epub 2017 Nov 2.


The effects of cannabidiol on persecutory ideation and anxiety in a high trait paranoid group.

Hundal H, Lister R, Evans N, Antley A, Englund A, Murray RM, Freeman D, Morrison PD.

J Psychopharmacol. 2018 Mar;32(3):276-282. doi: 10.1177/0269881117737400. Epub 2017 Oct 31.


Remission and recovery from first-episode psychosis in adults: systematic review and meta-analysis of long-term outcome studies.

Lally J, Ajnakina O, Stubbs B, Cullinane M, Murphy KC, Gaughran F, Murray RM.

Br J Psychiatry. 2017 Dec;211(6):350-358. doi: 10.1192/bjp.bp.117.201475. Epub 2017 Oct 5. Review.


The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) consortium: A collaborative cognitive and neuroimaging genetics project.

Blokland GAM, Del Re EC, Mesholam-Gately RI, Jovicich J, Trampush JW, Keshavan MS, DeLisi LE, Walters JTR, Turner JA, Malhotra AK, Lencz T, Shenton ME, Voineskos AN, Rujescu D, Giegling I, Kahn RS, Roffman JL, Holt DJ, Ehrlich S, Kikinis Z, Dazzan P, Murray RM, Di Forti M, Lee J, Sim K, Lam M, Wolthusen RPF, de Zwarte SMC, Walton E, Cosgrove D, Kelly S, Maleki N, Osiecki L, Picchioni MM, Bramon E, Russo M, David AS, Mondelli V, Reinders AATS, Falcone MA, Hartmann AM, Konte B, Morris DW, Gill M, Corvin AP, Cahn W, Ho NF, Liu JJ, Keefe RSE, Gollub RL, Manoach DS, Calhoun VD, Schulz SC, Sponheim SR, Goff DC, Buka SL, Cherkerzian S, Thermenos HW, Kubicki M, Nestor PG, Dickie EW, Vassos E, Ciufolini S, Reis Marques T, Crossley NA, Purcell SM, Smoller JW, van Haren NEM, Toulopoulou T, Donohoe G, Goldstein JM, Seidman LJ, McCarley RW, Petryshen TL.

Schizophr Res. 2018 May;195:306-317. doi: 10.1016/j.schres.2017.09.024. Epub 2017 Oct 3.


30 Years on: How the Neurodevelopmental Hypothesis of Schizophrenia Morphed Into the Developmental Risk Factor Model of Psychosis.

Murray RM, Bhavsar V, Tripoli G, Howes O.

Schizophr Bull. 2017 Oct 21;43(6):1190-1196. doi: 10.1093/schbul/sbx121.


Authors' reply.

Falkenberg I, Benetti S, Raffin M, Wuyts P, Pettersson-Yeo W, Dazzan P, Morgan KD, Murray RM, Marques TR, David AS, Jarosz J, Simmons A, Williams S, McGuire P.

Br J Psychiatry. 2017 Oct;211(4):250. doi: 10.1192/bjp.211.4.250a. No abstract available.


Volumetric grey matter alterations in adolescents and adults born very preterm suggest accelerated brain maturation.

Karolis VR, Froudist-Walsh S, Kroll J, Brittain PJ, Tseng CJ, Nam KW, Reinders AATS, Murray RM, Williams SCR, Thompson PM, Nosarti C.

Neuroimage. 2017 Dec;163:379-389. doi: 10.1016/j.neuroimage.2017.09.039. Epub 2017 Sep 20.


Brain-relevant antibodies in first-episode psychosis: a matched case-control study.

Gaughran F, Lally J, Beck K, McCormack R, Gardner-Sood P, Coutinho E, Jacobson L, Lang B, Sainz-Fuertes R, Papanastasiou E, Di Forti M, Nicholson T, Vincent A, Murray RM.

Psychol Med. 2018 Jun;48(8):1257-1263. doi: 10.1017/S0033291717002689. Epub 2017 Sep 18.


A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains.

Ranlund S, Calafato S, Thygesen JH, Lin K, Cahn W, Crespo-Facorro B, de Zwarte SMC, Díez Á, Di Forti M; GROUP, Iyegbe C, Jablensky A, Jones R, Hall MH, Kahn R, Kalaydjieva L, Kravariti E, McDonald C, McIntosh AM, McQuillin A; PEIC, Picchioni M, Prata DP, Rujescu D, Schulze K, Shaikh M, Toulopoulou T, van Haren N, van Os J, Vassos E, Walshe M; WTCCC2, Lewis C, Murray RM, Powell J, Bramon E.

Am J Med Genet B Neuropsychiatr Genet. 2018 Jan;177(1):21-34. doi: 10.1002/ajmg.b.32581. Epub 2017 Aug 29.


Only a small proportion of patients with first episode psychosis come via prodromal services: a retrospective survey of a large UK mental health programme.

Ajnakina O, Morgan C, Gayer-Anderson C, Oduola S, Bourque F, Bramley S, Williamson J, MacCabe JH, Dazzan P, Murray RM, David AS.

BMC Psychiatry. 2017 Aug 25;17(1):308. doi: 10.1186/s12888-017-1468-y.


Cell-free extract based optimization of biomolecular circuits with droplet microfluidics.

Hori Y, Kantak C, Murray RM, Abate AR.

Lab Chip. 2017 Sep 12;17(18):3037-3042. doi: 10.1039/c7lc00552k.


Hyperprolactinaemia in first episode psychosis - A longitudinal assessment.

Lally J, Ajnakina O, Stubbs B, Williams HR, Colizzi M, Carra E, Fraietta S, Gardner-Sood P, Greenwood KE, Atakan Z, Mondelli V, Ismail K, Howes O, Taylor DM, Smith S, Hopkins D, Murray RM, Gaughran F.

Schizophr Res. 2017 Nov;189:117-125. doi: 10.1016/j.schres.2017.07.037. Epub 2017 Jul 27.


Utilising symptom dimensions with diagnostic categories improves prediction of time to first remission in first-episode psychosis.

Ajnakina O, Lally J, Di Forti M, Stilo SA, Kolliakou A, Gardner-Sood P, Dazzan P, Pariante C, Reis Marques T, Mondelli V, MacCabe J, Gaughran F, David AS, Stamate D, Murray RM, Fisher HL.

Schizophr Res. 2018 Mar;193:391-398. doi: 10.1016/j.schres.2017.07.042. Epub 2017 Jul 26.


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