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Items: 1 to 50 of 198

1.

The expression of brown fat-associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis.

Alnabulsi A, Cash B, Hu Y, Silina L, Alnabulsi A, Murray GI.

Int J Cancer. 2019 Aug 15;145(4):1138-1147. doi: 10.1002/ijc.32198. Epub 2019 Mar 2.

PMID:
30737786
2.

Recent advances in understanding the roles of matrix metalloproteinases in tumour invasion and metastasis.

Conlon GA, Murray GI.

J Pathol. 2019 Apr;247(5):629-640. doi: 10.1002/path.5225. Epub 2019 Feb 15. Review.

PMID:
30582157
3.

Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes.

Alexandrou C, Al-Aqbi SS, Higgins JA, Boyle W, Karmokar A, Andreadi C, Luo JL, Moore DA, Viskaduraki M, Blades M, Murray GI, Howells LM, Thomas A, Brown K, Cheng PN, Rufini A.

Sci Rep. 2018 Aug 14;8(1):12096. doi: 10.1038/s41598-018-30591-7.

4.

Transcriptional subtyping and CD8 immunohistochemistry identifies poor prognosis stage II/III colorectal cancer patients who benefit from adjuvant chemotherapy.

Allen WL, Dunne PD, McDade S, Scanlon E, Loughrey M, Coleman H, McCann C, McLaughlin K, Nemeth Z, Syed N, Jithesh P, Arthur K, Wilson R, Coyle V, McArt D, Murray GI, Samuel L, Nuciforo P, Jimenez J, Argiles G, Dienstmann R, Tabernero J, Messerini L, Nobili S, Mini E, Sheahan K, Ryan E, Johnston PG, Van Schaeybroeck S, Lawler M, Longley DB.

JCO Precis Oncol. 2018 Jun 13;2018. doi: 10.1200/PO.17.00241.

5.

Combined linkage and association analysis of classical Hodgkin lymphoma.

Lawrie A, Han S, Sud A, Hosking F, Cezard T, Turner D, Clark C, Murray GI, Culligan DJ, Houlston RS, Vickers MA.

Oncotarget. 2018 Apr 17;9(29):20377-20385. doi: 10.18632/oncotarget.24872. eCollection 2018 Apr 17.

6.

Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress.

Port J, Muthalagu N, Raja M, Ceteci F, Monteverde T, Kruspig B, Hedley A, Kalna G, Lilla S, Neilson L, Brucoli M, Gyuraszova K, Tait-Mulder J, Mezna M, Svambaryte S, Bryson A, Sumpton D, McVie A, Nixon C, Drysdale M, Esumi H, Murray GI, Sansom OJ, Zanivan SR, Murphy DJ.

Cancer Discov. 2018 May;8(5):632-647. doi: 10.1158/2159-8290.CD-17-0533. Epub 2018 Mar 2.

7.

Extensive esophageal papillomatosis after chemoradiotherapy for squamous cell carcinoma.

Siu W, Murray GI, McKinlay A, Phull P.

Gastrointest Endosc. 2018 Jun;87(6):1581-1582. doi: 10.1016/j.gie.2017.12.001. Epub 2017 Dec 6. No abstract available.

PMID:
29223386
8.

Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia.

Le Sommer S, Morrice N, Pesaresi M, Thompson D, Vickers MA, Murray GI, Mody N, Neel BG, Bence KK, Wilson HM, Delibegović M.

Cancer Res. 2018 Jan 1;78(1):75-87. doi: 10.1158/0008-5472.CAN-17-0946. Epub 2017 Nov 9.

9.

Proteomics for early detection of colorectal cancer: recent updates.

Alnabulsi A, Murray GI.

Expert Rev Proteomics. 2018 Jan;15(1):55-63. doi: 10.1080/14789450.2018.1396893. Epub 2017 Nov 6. Review.

PMID:
29064727
10.

Natural killer-like signature observed post therapy in locally advanced rectal cancer is a determinant of pathological response and improved survival.

Alderdice M, Dunne PD, Cole AJ, O'Reilly PG, McArt DG, Bingham V, Fuchs MA, McQuaid S, Loughrey MB, Murray GI, Samuel LM, Lawler M, Wilson RH, Salto-Tellez M, Coyle VM.

Mod Pathol. 2017 Sep;30(9):1287-1298. doi: 10.1038/modpathol.2017.47. Epub 2017 Jun 16.

11.

Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies.

Alvi MA, Loughrey MB, Dunne P, McQuaid S, Turkington R, Fuchs MA, McGready C, Bingham V, Pang B, Moore W, Maxwell P, Lawler M, James JA, Murray GI, Wilson RH, Salto-Tellez M.

Br J Cancer. 2017 Jul 11;117(2):203-209. doi: 10.1038/bjc.2017.168. Epub 2017 Jun 8.

12.

The differential expression of omega-3 and omega-6 fatty acid metabolising enzymes in colorectal cancer and its prognostic significance.

Alnabulsi A, Swan R, Cash B, Alnabulsi A, Murray GI.

Br J Cancer. 2017 Jun 6;116(12):1612-1620. doi: 10.1038/bjc.2017.135. Epub 2017 May 30.

13.

Gefitinib and EGFR Gene Copy Number Aberrations in Esophageal Cancer.

Petty RD, Dahle-Smith A, Stevenson DAJ, Osborne A, Massie D, Clark C, Murray GI, Dutton SJ, Roberts C, Chong IY, Mansoor W, Thompson J, Harrison M, Chatterjee A, Falk SJ, Elyan S, Garcia-Alonso A, Fyfe DW, Wadsley J, Chau I, Ferry DR, Miedzybrodzka Z.

J Clin Oncol. 2017 Jul 10;35(20):2279-2287. doi: 10.1200/JCO.2016.70.3934. Epub 2017 May 24.

PMID:
28537764
14.

TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells.

Diamantopoulou Z, White G, Fadlullah MZH, Dreger M, Pickering K, Maltas J, Ashton G, MacLeod R, Baillie GS, Kouskoff V, Lacaud G, Murray GI, Sansom OJ, Hurlstone AFL, Malliri A.

Cancer Cell. 2017 May 8;31(5):621-634.e6. doi: 10.1016/j.ccell.2017.03.007. Epub 2017 Apr 13.

15.

Extending colonic mucosal microbiome analysis-assessment of colonic lavage as a proxy for endoscopic colonic biopsies.

Watt E, Gemmell MR, Berry S, Glaire M, Farquharson F, Louis P, Murray GI, El-Omar E, Hold GL.

Microbiome. 2016 Nov 25;4(1):61.

16.

Integrative analysis of the colorectal cancer proteome: potential clinical impact.

Alnabulsi A, Murray GI.

Expert Rev Proteomics. 2016 Oct;13(10):917-927. doi: 10.1080/14789450.2016.1233062. Epub 2016 Sep 19.

PMID:
27598033
17.

Transporters for Antiretroviral Drugs in Colorectal CD4+ T Cells and Circulating α4β7 Integrin CD4+ T Cells: Implications for HIV Microbicides.

Mukhopadhya I, Murray GI, Duncan L, Yuecel R, Shattock R, Kelly C, Iannelli F, Pozzi G, El-Omar EM, Hold GL, Hijazi K.

Mol Pharm. 2016 Sep 6;13(9):3334-40. doi: 10.1021/acs.molpharmaceut.6b00351. Epub 2016 Aug 11.

PMID:
27467446
18.

Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.

Swan R, Alnabulsi A, Cash B, Alnabulsi A, Murray GI.

Oncotarget. 2016 Jul 19;7(29):46509-46527. doi: 10.18632/oncotarget.10224.

19.

Tumour expression of leptin is associated with chemotherapy resistance and therapy-independent prognosis in gastro-oesophageal adenocarcinomas.

Bain GH, Collie-Duguid E, Murray GI, Gilbert FJ, Denison A, Mckiddie F, Ahearn T, Fleming I, Leeds J, Phull P, Park K, Nanthakumaran S, Matula KM, Grabsch HI, Tan P, Welch A, Schweiger L, Dahle-Smith A, Urquhart G, Finegan M, Petty RD.

Br J Cancer. 2016 Jun 14;114(12):e18. doi: 10.1038/bjc.2016.139. Epub 2016 May 26. No abstract available.

20.

The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma.

Mohamed A, Sun C, De Mello V, Selfe J, Missiaglia E, Shipley J, Murray GI, Zammit PS, Wackerhage H.

J Pathol. 2016 Sep;240(1):3-14. doi: 10.1002/path.4745.

21.

β-Glucan exacerbates allergic airway responses to house dust mite allergen.

Hadebe S, Kirstein F, Fierens K, Redelinghuys P, Murray GI, Williams DL, Lambrecht BN, Brombacher F, Brown GD.

Respir Res. 2016 Apr 2;17:35. doi: 10.1186/s12931-016-0352-5.

22.

A Comprehensive Study of Extramural Venous Invasion in Colorectal Cancer.

McClelland D, Murray GI.

PLoS One. 2015 Dec 15;10(12):e0144987. doi: 10.1371/journal.pone.0144987. eCollection 2015.

23.

Tumour expression of leptin is associated with chemotherapy resistance and therapy-independent prognosis in gastro-oesophageal adenocarcinomas.

Bain GH, Collie-Duguid E, Murray GI, Gilbert FJ, Denison A, Mckiddie F, Ahearn T, Fleming I, Leeds J, Phull P, Park K, Nanthakumaran S, Matula KM, Grabsch HI, Tan P, Welch A, Schweiger L, Dahle-Smith A, Urquhart G, Finegan M, Petty RD.

Br J Cancer. 2015 Dec 1;113(11):1641. doi: 10.1038/bjc.2015.391. No abstract available. Erratum in: Br J Cancer. 2016 Jun 14;114(12):e18.

24.

Progress in the development of protein biomarkers of oesophageal and gastric cancers.

Coghlin C, Murray GI.

Proteomics Clin Appl. 2016 Apr;10(4):532-45. doi: 10.1002/prca.201500079. Epub 2016 Jan 5. Review.

PMID:
26582241
25.

Drug transporter gene expression in human colorectal tissue and cell lines: modulation with antiretrovirals for microbicide optimization.

Mukhopadhya I, Murray GI, Berry S, Thomson J, Frank B, Gwozdz G, Ekeruche-Makinde J, Shattock R, Kelly C, Iannelli F, Pozzi G, El-Omar EM, Hold GL, Hijazi K.

J Antimicrob Chemother. 2016 Feb;71(2):372-86. doi: 10.1093/jac/dkv335. Epub 2015 Oct 29.

PMID:
26514157
26.

Epidermal Growth Factor (EGFR) copy number aberrations in esophageal and gastro-esophageal junctional carcinoma.

Dahle-Smith Å, Stevenson D, Massie D, Murray GI, Dutton SJ, Roberts C, Ferry D, Osborne A, Clark C, Petty RD, Miedzybrodzka Z.

Mol Cytogenet. 2015 Oct 17;8:78. doi: 10.1186/s13039-015-0181-0. eCollection 2015.

27.

MICL controls inflammation in rheumatoid arthritis.

Redelinghuys P, Whitehead L, Augello A, Drummond RA, Levesque JM, Vautier S, Reid DM, Kerscher B, Taylor JA, Nigrovic PA, Wright J, Murray GI, Willment JA, Hocking LJ, Fernandes MJ, De Bari C, Mcinnes IB, Brown GD.

Ann Rheum Dis. 2016 Jul;75(7):1386-91. doi: 10.1136/annrheumdis-2014-206644. Epub 2015 Aug 14.

28.

The expression and prognostic significance of bcl-2-associated transcription factor 1 in rectal cancer following neoadjuvant therapy.

Brown GT, Cash B, Alnabulsi A, Samuel LM, Murray GI.

Histopathology. 2016 Mar;68(4):556-66. doi: 10.1111/his.12780. Epub 2015 Sep 17.

PMID:
26183150
29.

Current mechanistic insights into the roles of matrix metalloproteinases in tumour invasion and metastasis.

Brown GT, Murray GI.

J Pathol. 2015 Nov;237(3):273-81. doi: 10.1002/path.4586. Epub 2015 Sep 10. Review.

PMID:
26174849
30.

Prognostic value of lymph node ratio and extramural vascular invasion on survival for patients undergoing curative colon cancer resection.

Parnaby CN, Scott NW, Ramsay G, MacKay C, Samuel L, Murray GI, Loudon MA.

Br J Cancer. 2015 Jul 14;113(2):212-9. doi: 10.1038/bjc.2015.211. Epub 2015 Jun 16.

31.

The Hippo signal transduction pathway in soft tissue sarcomas.

Mohamed AD, Tremblay AM, Murray GI, Wackerhage H.

Biochim Biophys Acta. 2015 Aug;1856(1):121-9. doi: 10.1016/j.bbcan.2015.05.006. Epub 2015 Jun 4. Review.

PMID:
26050962
32.

CYP3A isoforms in Ewing's sarcoma tumours: an immunohistochemical study with clinical correlation.

Zia H, Murray GI, Vyhlidal CA, Leeder JS, Anwar AE, Bui MM, Ahmed AA.

Int J Exp Pathol. 2015 Apr;96(2):81-6. doi: 10.1111/iep.12115. Epub 2015 Feb 9.

33.

Candida albicans colonization and dissemination from the murine gastrointestinal tract: the influence of morphology and Th17 immunity.

Vautier S, Drummond RA, Chen K, Murray GI, Kadosh D, Brown AJ, Gow NA, MacCallum DM, Kolls JK, Brown GD.

Cell Microbiol. 2015 Apr;17(4):445-50. doi: 10.1111/cmi.12388. Epub 2014 Nov 25.

34.

Biomarkers of colorectal cancer: recent advances and future challenges.

Coghlin C, Murray GI.

Proteomics Clin Appl. 2015 Feb;9(1-2):64-71. doi: 10.1002/prca.201400082. Epub 2015 Jan 12. Review.

PMID:
25311658
35.

Increased lymph node yield in colorectal cancer is not necessarily associated with a greater number of lymph node positive cancers.

O'Shea A, Aly O, Parnaby CN, Loudon MA, Samuel LM, Murray GI.

PLoS One. 2014 Aug 13;9(8):e104991. doi: 10.1371/journal.pone.0104991. eCollection 2014.

36.

The role of gene regulatory networks in promoting cancer progression and metastasis.

Coghlin C, Murray GI.

Future Oncol. 2014 Apr;10(5):735-48. doi: 10.2217/fon.13.264. Review.

PMID:
24799055
37.

Influence of HPV type on prognosis in patients diagnosed with invasive cervical cancer.

Cuschieri K, Brewster DH, Graham C, Nicoll S, Williams AR, Murray GI, Millan D, Johannessen I, Hardie A, Cubie HA.

Int J Cancer. 2014 Dec 1;135(11):2721-6. doi: 10.1002/ijc.28902. Epub 2014 Apr 29.

38.

The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer.

Brown GT, Cash BG, Blihoghe D, Johansson P, Alnabulsi A, Murray GI.

PLoS One. 2014 Mar 7;9(3):e90776. doi: 10.1371/journal.pone.0090776. eCollection 2014.

39.

Tumour expression of leptin is associated with chemotherapy resistance and therapy-independent prognosis in gastro-oesophageal adenocarcinomas.

Bain GH, Collie-Duguid E, Murray GI, Gilbert FJ, Denison A, McKiddie F, Ahearn T, Fleming I, Leeds J, Phull P, Park K, Nanthakumaran S, Matula KM, Grabsch HI, Tan P, Welch A, Schweiger L, Dahle-Smith A, Urquhart G, Finegan M, Petty RD.

Br J Cancer. 2014 Mar 18;110(6):1525-34. doi: 10.1038/bjc.2014.45. Epub 2014 Feb 25. Erratum in: Br J Cancer. 2015 Dec 1;113(11):1641. Matula, K M [added].

40.

Progress in the identification of plasma biomarkers of colorectal cancer.

Coghlin C, Murray GI.

Proteomics. 2013 Aug;13(15):2227-8. doi: 10.1002/pmic.201300245.

PMID:
23818135
41.

Expression of neutrophil gelatinase-associated lipocalin in colorectal neoplastic progression: a marker of malignant potential?

McLean MH, Thomson AJ, Murray GI, Fyfe N, Hold GL, El-Omar EM.

Br J Cancer. 2013 Jun 25;108(12):2537-41. doi: 10.1038/bjc.2013.264. Epub 2013 Jun 4.

42.

ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation.

Myant KB, Cammareri P, McGhee EJ, Ridgway RA, Huels DJ, Cordero JB, Schwitalla S, Kalna G, Ogg EL, Athineos D, Timpson P, Vidal M, Murray GI, Greten FR, Anderson KI, Sansom OJ.

Cell Stem Cell. 2013 Jun 6;12(6):761-73. doi: 10.1016/j.stem.2013.04.006. Epub 2013 May 9.

43.

Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1.

Marakalala MJ, Vautier S, Potrykus J, Walker LA, Shepardson KM, Hopke A, Mora-Montes HM, Kerrigan A, Netea MG, Murray GI, Maccallum DM, Wheeler R, Munro CA, Gow NA, Cramer RA, Brown AJ, Brown GD.

PLoS Pathog. 2013;9(4):e1003315. doi: 10.1371/journal.ppat.1003315. Epub 2013 Apr 18.

44.

Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.

Lourenço FC, Munro J, Brown J, Cordero J, Stefanatos R, Strathdee K, Orange C, Feller SM, Sansom OJ, Vidal M, Murray GI, Olson MF.

Gut. 2014 Mar;63(3):480-93. doi: 10.1136/gutjnl-2012-303883. Epub 2013 Apr 12.

45.

Raf kinase inhibitor protein expression combined with peritoneal involvement and lymphovascular invasion predicts prognosis in Dukes' B colorectal cancer patients.

Doyle B, Hagan S, Al-Mulla F, Scott L, Harden S, Paul J, Mulcahy H, Murray GI, Sheahan K, O'Sullivan J, Kolch W.

Histopathology. 2013 Feb;62(3):505-10.

PMID:
23460950
46.

Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis.

Baker AM, Bird D, Welti JC, Gourlaouen M, Lang G, Murray GI, Reynolds AR, Cox TR, Erler JT.

Cancer Res. 2013 Jan 15;73(2):583-94. doi: 10.1158/0008-5472.CAN-12-2447. Epub 2012 Nov 27.

47.

The proteomics of formalin-fixed wax-embedded tissue.

Vincenti DC, Murray GI.

Clin Biochem. 2013 Apr;46(6):546-51. doi: 10.1016/j.clinbiochem.2012.10.002. Epub 2012 Oct 9. Review.

PMID:
23063984
48.

Dectin-1 is not required for controlling Candida albicans colonization of the gastrointestinal tract.

Vautier S, Drummond RA, Redelinghuys P, Murray GI, MacCallum DM, Brown GD.

Infect Immun. 2012 Dec;80(12):4216-22. doi: 10.1128/IAI.00559-12. Epub 2012 Sep 17.

49.

Has the proteome of formalin-fixed wax-embedded tissue been unlocked?

Murray GI.

Nephrol Dial Transplant. 2012 Sep;27(9):3395-8. doi: 10.1093/ndt/gfs342. Epub 2012 Aug 1. No abstract available.

PMID:
22859788
50.

Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia: a case-control and immunohistochemical study.

Smith C, Lochhead P, Basavaraju U, Hold GL, Fyfe N, Murray GI, El-Omar EM.

BMC Res Notes. 2012 Jul 23;5:371. doi: 10.1186/1756-0500-5-371.

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