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Items: 1 to 50 of 156

1.

Sustained interleukin-10 delivery reduces inflammation and improves motor function after spinal cord injury.

Hellenbrand DJ, Reichl KA, Travis BJ, Filipp ME, Khalil AS, Pulito DJ, Gavigan AV, Maginot ER, Arnold MT, Adler AG, Murphy WL, Hanna AS.

J Neuroinflammation. 2019 Apr 30;16(1):93. doi: 10.1186/s12974-019-1479-3.

2.

Injectable biomaterials for delivery of interleukin-1 receptor antagonist: Toward improving its therapeutic effect.

Clements AEB, Murphy WL.

Acta Biomater. 2019 Apr 25. pii: S1742-7061(19)30294-6. doi: 10.1016/j.actbio.2019.04.051. [Epub ahead of print] Review.

PMID:
31029831
3.

A microparticle approach for non-viral gene delivery within 3D human mesenchymal stromal cell aggregates.

Khalil AS, Yu X, Dang PN, Alsberg E, Murphy WL.

Acta Biomater. 2019 Apr 18. pii: S1742-7061(19)30281-8. doi: 10.1016/j.actbio.2019.04.038. [Epub ahead of print]

PMID:
31004846
4.

A Reliable and Reproducible Critical-Sized Segmental Femoral Defect Model in Rats Stabilized with a Custom External Fixator.

Kerzner B, Martin HL, Weiser M, Fontana G, Russell N, Murphy WL, Lund EA, Doro CJ.

J Vis Exp. 2019 Mar 24;(145). doi: 10.3791/59206.

PMID:
30958483
5.

VEGF-loaded mineral-coated microparticles improve bone repair and are associated with increased expression of epo and RUNX-2 in murine non-unions.

Orth M, Shenar AK, Scheuer C, Braun BJ, Herath SC, Holstein JH, Histing T, Yu X, Murphy WL, Pohlemann T, Laschke MW, Menger MD.

J Orthop Res. 2019 Apr;37(4):821-831. doi: 10.1002/jor.24267. Epub 2019 Mar 28.

PMID:
30835895
6.

Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels.

Kaushik G, Gil DA, Torr E, Berge ES, Soref C, Uhl P, Fontana G, Antosiewicz-Bourget J, Edington C, Schwartz MP, Griffith LG, Thomson JA, Skala MC, Daly WT, Murphy WL.

Adv Healthc Mater. 2019 Jan;8(2):e1801186. doi: 10.1002/adhm.201801186. Epub 2018 Dec 19.

PMID:
30565891
7.

Synthetic, Chemically Defined Polymer-Coated Microcarriers for the Expansion of Human Mesenchymal Stem Cells.

Krutty JD, Dias AD, Yun J, Murphy WL, Gopalan P.

Macromol Biosci. 2019 Feb;19(2):e1800299. doi: 10.1002/mabi.201800299. Epub 2018 Nov 22.

PMID:
30565870
8.

Dynamic, Bioresponsive Hydrogels via Changes in DNA Aptamer Conformation.

Bae SW, Lee JS, Harms VM, Murphy WL.

Macromol Biosci. 2019 Feb;19(2):e1800353. doi: 10.1002/mabi.201800353. Epub 2018 Nov 22.

PMID:
30565861
10.

Customizable biomaterials as tools for advanced anti-angiogenic drug discovery.

Nguyen EH, Murphy WL.

Biomaterials. 2018 Oct;181:53-66. doi: 10.1016/j.biomaterials.2018.07.041. Epub 2018 Jul 26. Review.

PMID:
30077137
11.

Microparticles Locally Deliver Active Interleukin-1 Receptor Antagonist In Vivo.

Clements AEB, Groves ER, Chamberlain CS, Vanderby R, Murphy WL.

Adv Healthc Mater. 2018 Aug;7(16):e1800263. doi: 10.1002/adhm.201800263. Epub 2018 Jul 4.

PMID:
29974661
12.

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications.

Adamski M, Fontana G, Gershlak JR, Gaudette GR, Le HD, Murphy WL.

J Vis Exp. 2018 May 31;(135). doi: 10.3791/57586.

13.

Dual non-viral gene delivery from microparticles within 3D high-density stem cell constructs for enhanced bone tissue engineering.

McMillan A, Nguyen MK, Gonzalez-Fernandez T, Ge P, Yu X, Murphy WL, Kelly DJ, Alsberg E.

Biomaterials. 2018 Apr;161:240-255. doi: 10.1016/j.biomaterials.2018.01.006. Epub 2018 Jan 3.

14.

Combination of Heparin Binding Peptide and Heparin Cell Surface Coatings for Mesenchymal Stem Cell Spheroid Assembly.

Lei J, Murphy WL, Temenoff JS.

Bioconjug Chem. 2018 Apr 18;29(4):878-884. doi: 10.1021/acs.bioconjchem.7b00757. Epub 2018 Jan 23.

15.

Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion.

Nguyen EH, Daly WT, Le NNT, Farnoodian M, Belair DG, Schwartz MP, Lebakken CS, Ananiev GE, Saghiri MA, Knudsen TB, Sheibani N, Murphy WL.

Nat Biomed Eng. 2017;1. pii: 0096. doi: 10.1038/s41551-017-0096. Epub 2017 Jul 11.

16.

Functionalization of microparticles with mineral coatings enhances non-viral transfection of primary human cells.

Khalil AS, Yu X, Xie AW, Fontana G, Umhoefer JM, Johnson HJ, Hookway TA, McDevitt TC, Murphy WL.

Sci Rep. 2017 Oct 27;7(1):14211. doi: 10.1038/s41598-017-14153-x.

17.

Controlled Self-assembly of Stem Cell Aggregates Instructs Pluripotency and Lineage Bias.

Xie AW, Binder BYK, Khalil AS, Schmitt SK, Johnson HJ, Zacharias NA, Murphy WL.

Sci Rep. 2017 Oct 25;7(1):14070. doi: 10.1038/s41598-017-14325-9.

18.

Bioengineering Solutions for Manufacturing Challenges in CAR T Cells.

Piscopo NJ, Mueller KP, Das A, Hematti P, Murphy WL, Palecek SP, Capitini CM, Saha K.

Biotechnol J. 2018 Feb;13(2). doi: 10.1002/biot.201700095. Epub 2017 Sep 18. Review.

19.

Impacts of Interleukin-17 Neutralization on the Inflammatory Response in a Healing Ligament.

Clements AE, Chamberlain CS, Leiferman EM, Murphy WL, Vanderby R.

J Cytokine Biol. 2017 May;2(1). pii: 113. Epub 2017 Apr 6.

20.

Functional characterization of human pluripotent stem cell-derived arterial endothelial cells.

Zhang J, Chu LF, Hou Z, Schwartz MP, Hacker T, Vickerman V, Swanson S, Leng N, Nguyen BK, Elwell A, Bolin J, Brown ME, Stewart R, Burlingham WJ, Murphy WL, Thomson JA.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6072-E6078. doi: 10.1073/pnas.1702295114. Epub 2017 Jul 10.

21.

Nanostructured Mineral Coatings Stabilize Proteins for Therapeutic Delivery.

Yu X, Biedrzycki AH, Khalil AS, Hess D, Umhoefer JM, Markel MD, Murphy WL.

Adv Mater. 2017 Sep;29(33). doi: 10.1002/adma.201701255. Epub 2017 Jul 4.

22.

Endochondral Ossification in Critical-Sized Bone Defects via Readily Implantable Scaffold-Free Stem Cell Constructs.

Dang PN, Herberg S, Varghai D, Riazi H, Varghai D, McMillan A, Awadallah A, Phillips LM, Jeon O, Nguyen MK, Dwivedi N, Yu X, Murphy WL, Alsberg E.

Stem Cells Transl Med. 2017 Jul;6(7):1644-1659. doi: 10.1002/sctm.16-0222. Epub 2017 Jun 8.

23.

Uniform neural tissue models produced on synthetic hydrogels using standard culture techniques.

Barry C, Schmitz MT, Propson NE, Hou Z, Zhang J, Nguyen BK, Bolin JM, Jiang P, McIntosh BE, Probasco MD, Swanson S, Stewart R, Thomson JA, Schwartz MP, Murphy WL.

Exp Biol Med (Maywood). 2017 Nov;242(17):1679-1689. doi: 10.1177/1535370217715028. Epub 2017 Jun 9.

24.

Microcarriers with Synthetic Hydrogel Surfaces for Stem Cell Expansion.

Dias AD, Elicson JM, Murphy WL.

Adv Healthc Mater. 2017 Aug;6(16). doi: 10.1002/adhm.201700072. Epub 2017 May 16.

25.

Level-specific amputations and resulting regenerative outcomes in the mouse distal phalanx.

Chamberlain CS, Jeffery JJ, Leiferman EM, Yildirim T, Sun X, Baer GS, Murphy WL, Vanderby R.

Wound Repair Regen. 2017 May;25(3):443-453. doi: 10.1111/wrr.12544. Epub 2017 Jul 5.

26.

Specific recruitment of circulating angiogenic cells using biomaterials as filters.

Parlato M, Molenda J, Murphy WL.

Acta Biomater. 2017 Jul 1;56:65-79. doi: 10.1016/j.actbio.2017.03.048. Epub 2017 Apr 1.

27.

A Genome-wide Analysis of Human Pluripotent Stem Cell-Derived Endothelial Cells in 2D or 3D Culture.

Zhang J, Schwartz MP, Hou Z, Bai Y, Ardalani H, Swanson S, Steill J, Ruotti V, Elwell A, Nguyen BK, Bolin J, Stewart R, Thomson JA, Murphy WL.

Stem Cell Reports. 2017 Apr 11;8(4):907-918. doi: 10.1016/j.stemcr.2017.02.014. Epub 2017 Mar 23.

28.

Biofunctionalized Plants as Diverse Biomaterials for Human Cell Culture.

Fontana G, Gershlak J, Adamski M, Lee JS, Matsumoto S, Le HD, Binder B, Wirth J, Gaudette G, Murphy WL.

Adv Healthc Mater. 2017 Apr;6(8). doi: 10.1002/adhm.201601225. Epub 2017 Mar 20.

29.

Mineral binding peptides with enhanced binding stability in serum.

Lee JS, Yu X, Wagoner Johnson AJ, Murphy WL.

Biomater Sci. 2017 Mar 28;5(4):663-668. doi: 10.1039/c6bm00928j.

PMID:
28261732
30.

Crossing kingdoms: Using decellularized plants as perfusable tissue engineering scaffolds.

Gershlak JR, Hernandez S, Fontana G, Perreault LR, Hansen KJ, Larson SA, Binder BY, Dolivo DM, Yang T, Dominko T, Rolle MW, Weathers PJ, Medina-Bolivar F, Cramer CL, Murphy WL, Gaudette GR.

Biomaterials. 2017 May;125:13-22. doi: 10.1016/j.biomaterials.2017.02.011. Epub 2017 Feb 10.

31.

Restenosis Inhibition and Re-differentiation of TGFβ/Smad3-activated Smooth Muscle Cells by Resveratrol.

Zhu Y, Takayama T, Wang B, Kent A, Zhang M, Binder BY, Urabe G, Shi Y, DiRenzo D, Goel SA, Zhou Y, Little C, Roenneburg DA, Shi XD, Li L, Murphy WL, Kent KC, Ke J, Guo LW.

Sci Rep. 2017 Feb 6;7:41916. doi: 10.1038/srep41916.

32.

The Influence of Biomaterials on Cytokine Production in 3D Cultures.

Regier MC, Montanez-Sauri SI, Schwartz MP, Murphy WL, Beebe DJ, Sung KE.

Biomacromolecules. 2017 Mar 13;18(3):709-718. doi: 10.1021/acs.biomac.6b01469. Epub 2017 Feb 16.

33.

BMP-2-coated mineral coated microparticles improve bone repair in atrophic non-unions.

Orth M, Kruse NJ, Braun BJ, Scheuer C, Holstein JH, Khalil A, Yu X, Murphy WL, Pohlemann T, Laschke MW, Menger MD.

Eur Cell Mater. 2017 Jan 2;33:1-12. doi: 10.22203/eCM.v033a01.

34.

Microstructural control of modular peptide release from microporous biphasic calcium phosphate.

Polak SJ, Lee JS, Murphy WL, Tadier S, Grémillard L, Lightcap IV, Wagoner Johnson AJ.

Mater Sci Eng C Mater Biol Appl. 2017 Mar 1;72:268-277. doi: 10.1016/j.msec.2016.11.054. Epub 2016 Nov 19.

PMID:
28024586
35.

Tissue engineering and regenerative approaches to improving the healing of large bone defects.

Verrier S, Alini M, Alsberg E, Buchman SR, Kelly D, Laschke MW, Menger MD, Murphy WL, Stegemann JP, Schütz M, Miclau T, Stoddart MJ, Evans C.

Eur Cell Mater. 2016 Jul 19;32:87-110. Review.

36.

FAMILY SCIOMYZIDAE.

Marinoni L, Murphy WL.

Zootaxa. 2016 Jun 14;4122(1):642-7. doi: 10.11646/zootaxa.4122.1.53.

PMID:
27395301
37.

Biology and immature stages of Pherbellia limbata (Diptera: Sciomyzidae), a parasitoid of the terrestrial snail Granaria frumentum.

Nerudová-Horsáková J, Murphy WL, Vala JC.

Zootaxa. 2016 May 30;4117(1):48-62. doi: 10.11646/zootaxa.4117.1.2.

PMID:
27395157
38.

Surface functionalization and dynamics of polymeric cell culture substrates.

Krutty JD, Schmitt SK, Gopalan P, Murphy WL.

Curr Opin Biotechnol. 2016 Aug;40:164-169. doi: 10.1016/j.copbio.2016.05.006. Epub 2016 Jun 14. Review.

PMID:
27314835
39.

Human iPSC-derived endothelial cell sprouting assay in synthetic hydrogel arrays.

Belair DG, Schwartz MP, Knudsen T, Murphy WL.

Acta Biomater. 2016 Jul 15;39:12-24. doi: 10.1016/j.actbio.2016.05.020. Epub 2016 May 13.

40.

Orthosilicic acid, Si(OH)4, stimulates osteoblast differentiation in vitro by upregulating miR-146a to antagonize NF-κB activation.

Zhou X, Moussa FM, Mankoci S, Ustriyana P, Zhang N, Abdelmagid S, Molenda J, Murphy WL, Safadi FF, Sahai N.

Acta Biomater. 2016 Jul 15;39:192-202. doi: 10.1016/j.actbio.2016.05.007. Epub 2016 May 6.

PMID:
27163405
41.

Immune modulation with primed mesenchymal stem cells delivered via biodegradable scaffold to repair an Achilles tendon segmental defect.

Aktas E, Chamberlain CS, Saether EE, Duenwald-Kuehl SE, Kondratko-Mittnacht J, Stitgen M, Lee JS, Clements AE, Murphy WL, Vanderby R.

J Orthop Res. 2017 Feb;35(2):269-280. doi: 10.1002/jor.23258. Epub 2016 Apr 25.

42.

Differential regulation of angiogenesis using degradable VEGF-binding microspheres.

Belair DG, Miller MJ, Wang S, Darjatmoko SR, Binder BYK, Sheibani N, Murphy WL.

Biomaterials. 2016 Jul;93:27-37. doi: 10.1016/j.biomaterials.2016.03.021. Epub 2016 Mar 16.

43.

Sustained release of neurotrophin-3 via calcium phosphate-coated sutures promotes axonal regeneration after spinal cord injury.

Hanna A, Thompson DL, Hellenbrand DJ, Lee JS, Madura CJ, Wesley MG, Dillon NJ, Sharma T, Enright CJ, Murphy WL.

J Neurosci Res. 2016 Jul;94(7):645-52. doi: 10.1002/jnr.23730. Epub 2016 Mar 26.

PMID:
27015737
44.

Regulating VEGF signaling in platelet concentrates via specific VEGF sequestering.

Belair DG, Le NN, Murphy WL.

Biomater Sci. 2016 May 26;4(5):819-25. doi: 10.1039/c5bm00633c. Epub 2016 Mar 24.

45.

Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels.

Zanotelli MR, Ardalani H, Zhang J, Hou Z, Nguyen EH, Swanson S, Nguyen BK, Bolin J, Elwell A, Bischel LL, Xie AW, Stewart R, Beebe DJ, Thomson JA, Schwartz MP, Murphy WL.

Acta Biomater. 2016 Apr 15;35:32-41. doi: 10.1016/j.actbio.2016.03.001. Epub 2016 Mar 2.

46.

Peptide Conjugation to a Polymer Coating via Native Chemical Ligation of Azlactones for Cell Culture.

Schmitt SK, Trebatoski DJ, Krutty JD, Xie AW, Rollins B, Murphy WL, Gopalan P.

Biomacromolecules. 2016 Mar 14;17(3):1040-7. doi: 10.1021/acs.biomac.5b01682. Epub 2016 Feb 15.

47.

Controlled Dual Growth Factor Delivery From Microparticles Incorporated Within Human Bone Marrow-Derived Mesenchymal Stem Cell Aggregates for Enhanced Bone Tissue Engineering via Endochondral Ossification.

Dang PN, Dwivedi N, Phillips LM, Yu X, Herberg S, Bowerman C, Solorio LD, Murphy WL, Alsberg E.

Stem Cells Transl Med. 2016 Feb;5(2):206-17. doi: 10.5966/sctm.2015-0115. Epub 2015 Dec 23.

48.

Mineral particles modulate osteo-chondrogenic differentiation of embryonic stem cell aggregates.

Wang Y, Yu X, Baker C, Murphy WL, McDevitt TC.

Acta Biomater. 2016 Jan;29:42-51. doi: 10.1016/j.actbio.2015.10.039. Epub 2015 Oct 24.

49.

Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin.

Pellett S, Schwartz MP, Tepp WH, Josephson R, Scherf JM, Pier CL, Thomson JA, Murphy WL, Johnson EA.

Sci Rep. 2015 Sep 28;5:14566. doi: 10.1038/srep14566.

50.

Human pluripotent stem cell-derived neural constructs for predicting neural toxicity.

Schwartz MP, Hou Z, Propson NE, Zhang J, Engstrom CJ, Santos Costa V, Jiang P, Nguyen BK, Bolin JM, Daly W, Wang Y, Stewart R, Page CD, Murphy WL, Thomson JA.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12516-21. doi: 10.1073/pnas.1516645112. Epub 2015 Sep 21.

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