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Genome-wide DNA methylation meta-analysis in the brains of suicide completers.

Policicchio S, Washer S, Viana J, Iatrou A, Burrage J, Hannon E, Turecki G, Kaminsky Z, Mill J, Dempster EL, Murphy TM.

Transl Psychiatry. 2020 Feb 19;10(1):69. doi: 10.1038/s41398-020-0752-7.


Management of Herniated Lumbar Disk Disease and Cauda Equina Syndrome in Pregnancy.

Ahern DP, Gibbons D, Johnson GP, Murphy TM, Schroeder GD, Vaccaro AR, Butler JS.

Clin Spine Surg. 2019 Dec;32(10):412-416. doi: 10.1097/BSD.0000000000000886.


Enhancing the Seeking Safety group intervention with trauma-sensitive yoga practice: A program evaluation.

Murphy TM, Dispenza F, Chang CY, Elston N, Rumsey A, Sinclair M, Curtis-Davidson R.

Complement Ther Clin Pract. 2019 May;35:308-315. doi: 10.1016/j.ctcp.2019.03.006. Epub 2019 Mar 13.


Editorial commentary: Single pill combination pharmacotherapy in the management of hypertension: Time to "triple-down"?

Murphy TM, McEvoy JW.

Trends Cardiovasc Med. 2020 Feb;30(2):78-79. doi: 10.1016/j.tcm.2019.04.001. Epub 2019 Apr 10. No abstract available.


Pulmonary vascular mechanical consequences of ischemic heart failure and implications for right ventricular function.

Philip JL, Murphy TM, Schreier DA, Stevens S, Tabima DM, Albrecht M, Frump AL, Hacker TA, Lahm T, Chesler NC.

Am J Physiol Heart Circ Physiol. 2019 May 1;316(5):H1167-H1177. doi: 10.1152/ajpheart.00319.2018. Epub 2019 Feb 15.


HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo.

Frum T, Murphy TM, Ralston A.

Elife. 2018 Dec 11;7. pii: e42298. doi: 10.7554/eLife.42298.


Iclaprim activity against wild-type and corresponding thymidine kinase-deficient Staphylococcus aureus in a mouse protection model.

Huang DB, Park JH, Murphy TM.

Eur J Clin Microbiol Infect Dis. 2019 Feb;38(2):409-412. doi: 10.1007/s10096-018-3440-2. Epub 2018 Nov 27.


Control of Confounding and Reporting of Results in Causal Inference Studies. Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals.

Lederer DJ, Bell SC, Branson RD, Chalmers JD, Marshall R, Maslove DM, Ost DE, Punjabi NM, Schatz M, Smyth AR, Stewart PW, Suissa S, Adjei AA, Akdis CA, Azoulay É, Bakker J, Ballas ZK, Bardin PG, Barreiro E, Bellomo R, Bernstein JA, Brusasco V, Buchman TG, Chokroverty S, Collop NA, Crapo JD, Fitzgerald DA, Hale L, Hart N, Herth FJ, Iwashyna TJ, Jenkins G, Kolb M, Marks GB, Mazzone P, Moorman JR, Murphy TM, Noah TL, Reynolds P, Riemann D, Russell RE, Sheikh A, Sotgiu G, Swenson ER, Szczesniak R, Szymusiak R, Teboul JL, Vincent JL.

Ann Am Thorac Soc. 2019 Jan;16(1):22-28. doi: 10.1513/AnnalsATS.201808-564PS. No abstract available. Erratum in: Ann Am Thorac Soc. 2019 Feb;16(2):283.


DNA methylation and inflammation marker profiles associated with a history of depression.

Crawford B, Craig Z, Mansell G, White I, Smith A, Spaull S, Imm J, Hannon E, Wood A, Yaghootkar H, Ji Y; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Mullins N, Lewis CM, Mill J, Murphy TM.

Hum Mol Genet. 2018 Aug 15;27(16):2840-2850. doi: 10.1093/hmg/ddy199.


Fluorocycline TP-271 Is Potent against Complicated Community-Acquired Bacterial Pneumonia Pathogens.

Grossman TH, Fyfe C, O'Brien W, Hackel M, Minyard MB, Waites KB, Dubois J, Murphy TM, Slee AM, Weiss WJ, Sutcliffe JA.

mSphere. 2017 Feb 22;2(1). pii: e00004-17. doi: 10.1128/mSphere.00004-17. eCollection 2017 Jan-Feb.


A comparison of HFrEF vs HFpEF's clinical workload and cost in the first year following hospitalization and enrollment in a disease management program.

Murphy TM, Waterhouse DF, James S, Casey C, Fitzgerald E, O'Connell E, Watson C, Gallagher J, Ledwidge M, McDonald K.

Int J Cardiol. 2017 Apr 1;232:330-335. doi: 10.1016/j.ijcard.2016.12.057. Epub 2016 Dec 23.


Methylomic profiling of cortex samples from completed suicide cases implicates a role for PSORS1C3 in major depression and suicide.

Murphy TM, Crawford B, Dempster EL, Hannon E, Burrage J, Turecki G, Kaminsky Z, Mill J.

Transl Psychiatry. 2017 Jan 3;7(1):e989. doi: 10.1038/tp.2016.249.


Mixture toxicity of phostebupirim and cyfluthrin: Species-specific responses.

de Perre C, Murphy TM, Lydy MJ.

Environ Toxicol Chem. 2017 Jul;36(7):1947-1954. doi: 10.1002/etc.3724. Epub 2017 Feb 6.


Fate and risk of atrazine and sulfentrazone to nontarget species at an agriculture site.

Thorngren JL, Harwood AD, Murphy TM, Huff Hartz KE, Fung CY, Lydy MJ.

Environ Toxicol Chem. 2017 May;36(5):1301-1310. doi: 10.1002/etc.3664. Epub 2016 Dec 6.


Severe right ventricular fibrosis.

Waterhouse DF, Murphy TM, Galvin J, O'Hanlon R.

Int J Cardiol. 2016 Oct 15;221:837-8. doi: 10.1016/j.ijcard.2016.06.258. Epub 2016 Jul 9. No abstract available.


Identification and Individualization of Lophophora using DNA Analysis of the trnL/trnF Region and rbcL Gene.

Ng AE, Sandoval E, Murphy TM.

J Forensic Sci. 2016 Jan;61 Suppl 1:S226-9. doi: 10.1111/1556-4029.12936. Epub 2015 Aug 27.


Particulate and non-particulate steroids in spinal epidurals: a systematic review and meta-analysis.

Feeley IH, Healy EF, Noel J, Kiely PJ, Murphy TM.

Eur Spine J. 2017 Feb;26(2):336-344. doi: 10.1007/s00586-016-4437-0. Epub 2016 Feb 12. Review.


Fate and transport of agriculturally applied fungicidal compounds, azoxystrobin and propiconazole.

Edwards PG, Murphy TM, Lydy MJ.

Chemosphere. 2016 Mar;146:450-7. doi: 10.1016/j.chemosphere.2015.11.116. Epub 2015 Dec 30.


Methylomic markers of persistent childhood asthma: a longitudinal study of asthma-discordant monozygotic twins.

Murphy TM, Wong CC, Arseneault L, Burrage J, Macdonald R, Hannon E, Fisher HL, Ambler A, Moffitt TE, Caspi A, Mill J.

Clin Epigenetics. 2015 Dec 18;7:130. doi: 10.1186/s13148-015-0163-4. eCollection 2015.


Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci.

Hannon E, Spiers H, Viana J, Pidsley R, Burrage J, Murphy TM, Troakes C, Turecki G, O'Donovan MC, Schalkwyk LC, Bray NJ, Mill J.

Nat Neurosci. 2016 Jan;19(1):48-54. doi: 10.1038/nn.4182. Epub 2015 Nov 30.


Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms.

Fisher HL, Murphy TM, Arseneault L, Caspi A, Moffitt TE, Viana J, Hannon E, Pidsley R, Burrage J, Dempster EL, Wong CC, Pariante CM, Mill J.

Epigenetics. 2015;10(11):1014-23. doi: 10.1080/15592294.2015.1099797.


DNA Methylation Profiling in Inflammatory Bowel Disease Provides New Insights into Disease Pathogenesis.

McDermott E, Ryan EJ, Tosetto M, Gibson D, Burrage J, Keegan D, Byrne K, Crowe E, Sexton G, Malone K, Harris RA, Kellermayer R, Mill J, Cullen G, Doherty GA, Mulcahy H, Murphy TM.

J Crohns Colitis. 2016 Jan;10(1):77-86. doi: 10.1093/ecco-jcc/jjv176. Epub 2015 Sep 28.


Evaluating the landscape of fear between apex predatory sharks and mobile sea turtles across a large dynamic seascape.

Hammerschlag N, Broderick AC, Coker JW, Coyne MS, Dodd M, Frick MG, Godfrey MH, Godley BJ, Griffin DB, Hartog K, Murphy SR, Murphy TM, Nelson ER, Williams KL, Witt MJ, Hawkes LA.

Ecology. 2015 Aug;96(8):2117-26.


An unusual cause of dynamic left ventricular outflow obstruction: An unusual case of dynamic LVOTO.

Waterhouse DF, Murphy TM, McCreery CJ, O'Hanlon R.

Int J Cardiol. 2015 Oct 15;197:282-3. doi: 10.1016/j.ijcard.2015.06.084. Epub 2015 Jul 3. No abstract available.


CMR detection of membraneous ventricular septal aneurysm causing ventricular tachycardia.

Murphy TM, Waterhouse DF, Maher V, O'Hanlon R.

Diagn Interv Imaging. 2015 Sep;96(9):963-4. doi: 10.1016/j.diii.2014.12.009. Epub 2015 Apr 24. No abstract available.


LV Apical Rupture Complicating Acute Myocardial Infarction: The Role of CMR.

Waterhouse DF, Murphy TM, McCarthy J, O'Neill J, O'Hanlon R.

Heart Lung Circ. 2015 Jul;24(7):e93-6. doi: 10.1016/j.hlc.2014.12.167. Epub 2015 Feb 24.


Eravacycline (TP-434) is efficacious in animal models of infection.

Grossman TH, Murphy TM, Slee AM, Lofland D, Sutcliffe JA.

Antimicrob Agents Chemother. 2015 May;59(5):2567-71. doi: 10.1128/AAC.04354-14. Epub 2015 Feb 17.


Ovalbumin sensitization of guinea pig at birth prevents the ontogenetic decrease in airway smooth muscle responsiveness.

Chitano P, Wang L, Degan S, Worthington CL, Pozzato V, Hussaini SH, Turner WC, Dorscheid DR, Murphy TM.

Physiol Rep. 2014 Dec 11;2(12). pii: e12241. doi: 10.14814/phy2.12241. Print 2014 Dec 1.


Surgical management of complex multiloculated hydrocephalus in infants and children.

Akbari SH, Holekamp TF, Murphy TM, Mercer D, Leonard JR, Smyth MD, Park TS, Limbrick DD Jr.

Childs Nerv Syst. 2015 Feb;31(2):243-9. doi: 10.1007/s00381-014-2596-z. Epub 2014 Nov 29.


Fate and effects of clothianidin in fields using conservation practices.

de Perre C, Murphy TM, Lydy MJ.

Environ Toxicol Chem. 2015 Feb;34(2):258-65. doi: 10.1002/etc.2800. Epub 2015 Jan 6.


Anxiety is associated with higher levels of global DNA methylation and altered expression of epigenetic and interleukin-6 genes.

Murphy TM, O'Donovan A, Mullins N, O'Farrelly C, McCann A, Malone K.

Psychiatr Genet. 2015 Apr;25(2):71-8. doi: 10.1097/YPG.0000000000000055.


Assessing the fate and effects of an insecticidal formulation.

de Perre C, Williard KW, Schoonover JE, Young BG, Murphy TM, Lydy MJ.

Environ Toxicol Chem. 2015 Jan;34(1):197-207. doi: 10.1002/etc.2786. Epub 2014 Dec 4.


Print-to-Pattern Dry Film Photoresist Lithography.

Garland SP, Murphy TM Jr, Pan T.

J Micromech Microeng. 2014 May 1;24(5):057002.


The ROAD to a focused view of airway smooth muscle and inflammatory cells in asthmatic sensitization: a tribute to Newman Stephens.

Murphy TM.

J Physiol. 2014 Jul 15;592(14):2915-6. doi: 10.1113/jphysiol.2014.275362. No abstract available.


Clinico-pathological analysis of renal cell carcinoma demonstrates decreasing tumour grade over a 17-year period.

Nason GJ, McGuire BB, Kelly ME, Murphy TM, Looney AT, Byrne DP, Mulvin DW, Galvin DJ, Quinlan DM, Lennon GM.

Can Urol Assoc J. 2014 Mar;8(3-4):125-32. doi: 10.5489/cuaj.1721.


Epigenetics in health and disease: heralding the EWAS era.

Murphy TM, Mill J.

Lancet. 2014 Jun 7;383(9933):1952-4. doi: 10.1016/S0140-6736(14)60269-5. Epub 2014 Mar 13. No abstract available.


Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents.

Tari LW, Li X, Trzoss M, Bensen DC, Chen Z, Lam T, Zhang J, Lee SJ, Hough G, Phillipson D, Akers-Rodriguez S, Cunningham ML, Kwan BP, Nelson KJ, Castellano A, Locke JB, Brown-Driver V, Murphy TM, Ong VS, Pillar CM, Shinabarger DL, Nix J, Lightstone FC, Wong SE, Nguyen TB, Shaw KJ, Finn J.

PLoS One. 2013 Dec 26;8(12):e84409. doi: 10.1371/journal.pone.0084409. eCollection 2013.


Panmictic structure of the Cryptosporidium parvum population in Irish calves: influence of prevalence and host movement.

De Waele V, Van den Broeck F, Huyse T, McGrath G, Higgins I, Speybroeck N, Berzano M, Raleigh P, Mulcahy GM, Murphy TM.

Appl Environ Microbiol. 2013 Apr;79(8):2534-41. doi: 10.1128/AEM.03613-12. Epub 2013 Feb 8.


Mining methylome databases.

O'Rourke CJ, Murphy TM, Hollywood D, Perry AS.

Trends Genet. 2013 Feb;29(2):63-5. doi: 10.1016/j.tig.2012.10.015. Epub 2012 Nov 23. No abstract available.


Genetic variation in DNMT3B and increased global DNA methylation is associated with suicide attempts in psychiatric patients.

Murphy TM, Mullins N, Ryan M, Foster T, Kelly C, McClelland R, O'Grady J, Corcoran E, Brady J, Reilly M, Jeffers A, Brown K, Maher A, Bannan N, Casement A, Lynch D, Bolger S, Buckley A, Quinlivan L, Daly L, Kelleher C, Malone KM.

Genes Brain Behav. 2013 Feb;12(1):125-32. doi: 10.1111/j.1601-183X.2012.00865.x. Epub 2012 Oct 26.


Airway contractility and remodeling: links to asthma symptoms.

West AR, Syyong HT, Siddiqui S, Pascoe CD, Murphy TM, Maarsingh H, Deng L, Maksym GN, Bossé Y.

Pulm Pharmacol Ther. 2013 Feb;26(1):3-12. doi: 10.1016/j.pupt.2012.08.009. Epub 2012 Sep 16. Review.


Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer.

Perry AS, O'Hurley G, Raheem OA, Brennan K, Wong S, O'Grady A, Kennedy AM, Marignol L, Murphy TM, Sullivan L, Barrett C, Loftus B, Thornhill J, Hewitt SM, Lawler M, Kay E, Lynch T, Hollywood D.

Int J Cancer. 2013 Apr 15;132(8):1771-80. doi: 10.1002/ijc.27798. Epub 2012 Sep 28. Erratum in: Int J Cancer. 2013 Jun 1;132(11):e163.


IGFBP7 promoter methylation and gene expression analysis in prostate cancer.

Sullivan L, Murphy TM, Barrett C, Loftus B, Thornhill J, Lawler M, Hollywood D, Lynch T, Perry AS.

J Urol. 2012 Oct;188(4):1354-60. doi: 10.1016/j.juro.2012.06.002. Epub 2012 Aug 17. Erratum in: J Urol. 2012 Dec;188(6):2443.


Freedom from Echinococcus multilocularis: an Irish perspective.

Murphy TM, Wahlström H, Dold C, Keegan JD, McCann A, Melville J, Murphy D, McAteer W.

Vet Parasitol. 2012 Nov 23;190(1-2):196-203. doi: 10.1016/j.vetpar.2012.05.009. Epub 2012 May 19.


Peri-parturient rise of Cryptosporidium oocysts in cows: new insights provided by duplex quantitative real-time PCR.

De Waele V, Berzano M, Speybroeck N, Berkvens D, Mulcahy GM, Murphy TM.

Vet Parasitol. 2012 Oct 26;189(2-4):366-8. doi: 10.1016/j.vetpar.2012.05.002. Epub 2012 May 11.


DNA identification of Salvia divinorum samples.

Murphy TM, Bola G.

Forensic Sci Int Genet. 2013 Jan;7(1):189-93. doi: 10.1016/j.fsigen.2012.04.004. Epub 2012 May 9.


The prevalence and distribution of Alaria alata, a potential zoonotic parasite, in foxes in Ireland.

Murphy TM, O'Connell J, Berzano M, Dold C, Keegan JD, McCann A, Murphy D, Holden NM.

Parasitol Res. 2012 Jul;111(1):283-90. doi: 10.1007/s00436-012-2835-8. Epub 2012 Feb 18.


Altered lipid metabolism in Hfe-knockout mice promotes severe NAFLD and early fibrosis.

Tan TC, Crawford DH, Jaskowski LA, Murphy TM, Heritage ML, Subramaniam VN, Clouston AD, Anderson GJ, Fletcher LM.

Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G865-76. doi: 10.1152/ajpgi.00150.2011. Epub 2011 Aug 4.


Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms.

Murphy TM, Ryan M, Foster T, Kelly C, McClelland R, O'Grady J, Corcoran E, Brady J, Reilly M, Jeffers A, Brown K, Maher A, Bannan N, Casement A, Lynch D, Bolger S, Tewari P, Buckley A, Quinlivan L, Daly L, Kelleher C, Malone KM.

Behav Brain Funct. 2011 Jun 28;7:22. doi: 10.1186/1744-9081-7-22.


Modelling Cryptosporidium oocysts transport in small ungauged agricultural catchments.

Tang J, McDonald S, Peng X, Samadder SR, Murphy TM, Holden NM.

Water Res. 2011 Jun;45(12):3665-80. doi: 10.1016/j.watres.2011.04.013. Epub 2011 Apr 23.


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