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Items: 1 to 50 of 168

1.

Podocalyxin is required for maintaining blood-brain barrier function during acute inflammation.

Cait J, Hughes MR, Zeglinski MR, Chan AW, Osterhof S, Scott RW, Canals Hernaez D, Cait A, Vogl AW, Bernatchez P, Underhill TM, Granville DJ, Murphy TH, Roskelley CD, McNagny KM.

Proc Natl Acad Sci U S A. 2019 Feb 20. pii: 201814766. doi: 10.1073/pnas.1814766116. [Epub ahead of print]

PMID:
30787191
2.

Longitudinal monitoring of mesoscopic cortical activity in a mouse model of microinfarcts reveals dissociations with behavioral and motor function.

Balbi M, Vanni MP, Vega MJ, Silasi G, Sekino Y, Boyd JD, LeDue JM, Murphy TH.

J Cereb Blood Flow Metab. 2019 Aug;39(8):1486-1500. doi: 10.1177/0271678X18763428. Epub 2018 Mar 9.

PMID:
29521138
3.

Good Vibrations: Resting-State Functional Connectivity Reflects Entrainment of Vasomotion.

Chan AW, Murphy TH.

Neuron. 2017 Nov 15;96(4):716-717. doi: 10.1016/j.neuron.2017.10.035.

4.

Executive dysfunction and blockage of brain microvessels in a rat model of vascular cognitive impairment.

Langdon KD, Cordova CA, Granter-Button S, Boyd JD, Peeling J, Murphy TH, Corbett D.

J Cereb Blood Flow Metab. 2018 Oct;38(10):1727-1740. doi: 10.1177/0271678X17739219. Epub 2017 Oct 30.

PMID:
29083274
5.

Individualized tracking of self-directed motor learning in group-housed mice performing a skilled lever positioning task in the home cage.

Silasi G, Boyd JD, Bolanos F, LeDue JM, Scott SH, Murphy TH.

J Neurophysiol. 2018 Jan 1;119(1):337-346. doi: 10.1152/jn.00115.2017. Epub 2017 Oct 25.

6.

An Automated Home-Cage System to Assess Learning and Performance of a Skilled Motor Task in a Mouse Model of Huntington's Disease.

Woodard CL, Bolaños F, Boyd JD, Silasi G, Murphy TH, Raymond LA.

eNeuro. 2017 Sep 18;4(5). pii: ENEURO.0141-17.2017. doi: 10.1523/ENEURO.0141-17.2017. eCollection 2017 Sep-Oct.

7.

Cortical functional hyperconnectivity in a mouse model of depression and selective network effects of ketamine.

McGirr A, LeDue J, Chan AW, Xie Y, Murphy TH.

Brain. 2017 Aug 1;140(8):2210-2225. doi: 10.1093/brain/awx142.

PMID:
28899017
8.

Automated touch sensing in the mouse tapered beam test using Raspberry Pi.

Ardesch DJ, Balbi M, Murphy TH.

J Neurosci Methods. 2017 Nov 1;291:221-226. doi: 10.1016/j.jneumeth.2017.08.030. Epub 2017 Aug 30.

PMID:
28860079
9.

Enhancing the Alignment of the Preclinical and Clinical Stroke Recovery Research Pipeline: Consensus-Based Core Recommendations From the Stroke Recovery and Rehabilitation Roundtable Translational Working Group.

Corbett D, Carmichael ST, Murphy TH, Jones TA, Schwab ME, Jolkkonen J, Clarkson AN, Dancause N, Weiloch T, Johansen-Berg H, Nilsson M, McCullough LD, Joy MT.

Neurorehabil Neural Repair. 2017 Aug;31(8):699-707. doi: 10.1177/1545968317724285.

PMID:
28803530
10.

Targeted ischemic stroke induction and mesoscopic imaging assessment of blood flow and ischemic depolarization in awake mice.

Balbi M, Vanni MP, Silasi G, Sekino Y, Bolanos L, LeDue JM, Murphy TH.

Neurophotonics. 2017 Jul;4(3):035001. doi: 10.1117/1.NPh.4.3.035001. Epub 2017 Jul 14.

11.

Enhancing the alignment of the preclinical and clinical stroke recovery research pipeline: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable translational working group.

Corbett D, Carmichael ST, Murphy TH, Jones TA, Schwab ME, Jolkkonen J, Clarkson AN, Dancause N, Wieloch T, Johansen-Berg H, Nilsson M, McCullough LD, Joy MT.

Int J Stroke. 2017 Jul;12(5):462-471. doi: 10.1177/1747493017711814. Erratum in: Int J Stroke. 2018 Jan;13(1):NP1.

PMID:
28697710
12.

Mesoscale Mapping of Mouse Cortex Reveals Frequency-Dependent Cycling between Distinct Macroscale Functional Modules.

Vanni MP, Chan AW, Balbi M, Silasi G, Murphy TH.

J Neurosci. 2017 Aug 2;37(31):7513-7533. doi: 10.1523/JNEUROSCI.3560-16.2017. Epub 2017 Jul 3.

13.

Mesoscale brain explorer, a flexible python-based image analysis and visualization tool.

Haupt D, Vanni MP, Bolanos F, Mitelut C, LeDue JM, Murphy TH.

Neurophotonics. 2017 Jul;4(3):031210. doi: 10.1117/1.NPh.4.3.031210. Epub 2017 May 19.

14.

Automating mouse weighing in group homecages with Raspberry Pi micro-computers.

Noorshams O, Boyd JD, Murphy TH.

J Neurosci Methods. 2017 Jun 15;285:1-5. doi: 10.1016/j.jneumeth.2017.05.002. Epub 2017 May 3.

PMID:
28476590
15.

A Visual Guide to Sorting Electrophysiological Recordings Using 'SpikeSorter'.

Swindale NV, Mitelut C, Murphy TH, Spacek MA.

J Vis Exp. 2017 Feb 10;(120). doi: 10.3791/55217.

16.

Mapping cortical mesoscopic networks of single spiking cortical or sub-cortical neurons.

Xiao D, Vanni MP, Mitelut CC, Chan AW, LeDue JM, Xie Y, Chen AC, Swindale NV, Murphy TH.

Elife. 2017 Feb 4;6. pii: e19976. doi: 10.7554/eLife.19976.

17.

Large Scale Cortical Functional Networks Associated with Slow-Wave and Spindle-Burst-Related Spontaneous Activity.

McVea DA, Murphy TH, Mohajerani MH.

Front Neural Circuits. 2016 Dec 21;10:103. doi: 10.3389/fncir.2016.00103. eCollection 2016. Review.

18.

Recent progress in translational research on neurovascular and neurodegenerative disorders.

Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, Rueger MA, Saur D, Savitz SI, Schilling S, Spratt NJ, Turner RJ, Vemuganti R, Vivien D, Yepes M, Zille M, Boltze J; ISN&N meeting contributors.

Restor Neurol Neurosci. 2017;35(1):87-103. doi: 10.3233/RNN-160690. Review.

19.

Cost effective raspberry pi-based radio frequency identification tagging of mice suitable for automated in vivo imaging.

Bolaños F, LeDue JM, Murphy TH.

J Neurosci Methods. 2017 Jan 30;276:79-83. doi: 10.1016/j.jneumeth.2016.11.011. Epub 2016 Nov 27.

PMID:
27899319
20.

Mapping synaptic glutamate transporter dysfunction in vivo to regions surrounding Aβ plaques by iGluSnFR two-photon imaging.

Hefendehl JK, LeDue J, Ko RW, Mahler J, Murphy TH, MacVicar BA.

Nat Commun. 2016 Nov 11;7:13441. doi: 10.1038/ncomms13441.

21.

Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2.

Connor SA, Ammendrup-Johnsen I, Chan AW, Kishimoto Y, Murayama C, Kurihara N, Tada A, Ge Y, Lu H, Yan R, LeDue JM, Matsumoto H, Kiyonari H, Kirino Y, Matsuzaki F, Suzuki T, Murphy TH, Wang YT, Yamamoto T, Craig AM.

Neuron. 2016 Sep 7;91(5):1052-1068. doi: 10.1016/j.neuron.2016.08.016.

22.

High-throughput automated home-cage mesoscopic functional imaging of mouse cortex.

Murphy TH, Boyd JD, Bolaños F, Vanni MP, Silasi G, Haupt D, LeDue JM.

Nat Commun. 2016 Jun 13;7:11611. doi: 10.1038/ncomms11611.

23.

Intact skull chronic windows for mesoscopic wide-field imaging in awake mice.

Silasi G, Xiao D, Vanni MP, Chen AC, Murphy TH.

J Neurosci Methods. 2016 Jul 15;267:141-9. doi: 10.1016/j.jneumeth.2016.04.012. Epub 2016 Apr 19.

24.

Re-Establishment of Cortical Motor Output Maps and Spontaneous Functional Recovery via Spared Dorsolaterally Projecting Corticospinal Neurons after Dorsal Column Spinal Cord Injury in Adult Mice.

Hilton BJ, Anenberg E, Harrison TC, Boyd JD, Murphy TH, Tetzlaff W.

J Neurosci. 2016 Apr 6;36(14):4080-92. doi: 10.1523/JNEUROSCI.3386-15.2016.

25.

Real-time imaging of glutamate clearance reveals normal striatal uptake in Huntington disease mouse models.

Parsons MP, Vanni MP, Woodard CL, Kang R, Murphy TH, Raymond LA.

Nat Commun. 2016 Apr 7;7:11251. doi: 10.1038/ncomms11251.

26.

Resolution of High-Frequency Mesoscale Intracortical Maps Using the Genetically Encoded Glutamate Sensor iGluSnFR.

Xie Y, Chan AW, McGirr A, Xue S, Xiao D, Zeng H, Murphy TH.

J Neurosci. 2016 Jan 27;36(4):1261-72. doi: 10.1523/JNEUROSCI.2744-15.2016.

27.

Special Section Guest Editorial:Special Section on Light Microscopy of Connectivity.

Zeng S, Murphy TH.

Neurophotonics. 2015 Oct;2(4):041401. doi: 10.1117/1.NPh.2.4.041401. Epub 2015 Nov 30. No abstract available.

28.

COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex.

Lacroix A, Toussay X, Anenberg E, Lecrux C, Ferreirós N, Karagiannis A, Plaisier F, Chausson P, Jarlier F, Burgess SA, Hillman EM, Tegeder I, Murphy TH, Hamel E, Cauli B.

J Neurosci. 2015 Aug 26;35(34):11791-810. doi: 10.1523/JNEUROSCI.0651-15.2015.

29.

Neocortical Rebound Depolarization Enhances Visual Perception.

Funayama K, Minamisawa G, Matsumoto N, Ban H, Chan AW, Matsuki N, Murphy TH, Ikegaya Y.

PLoS Biol. 2015 Aug 14;13(8):e1002231. doi: 10.1371/journal.pbio.1002231. eCollection 2015 Aug.

30.

Mesoscale infraslow spontaneous membrane potential fluctuations recapitulate high-frequency activity cortical motifs.

Chan AW, Mohajerani MH, LeDue JM, Wang YT, Murphy TH.

Nat Commun. 2015 Jul 20;6:7738. doi: 10.1038/ncomms8738.

31.

Network analysis of mesoscale optical recordings to assess regional, functional connectivity.

Lim DH, LeDue JM, Murphy TH.

Neurophotonics. 2015 Oct;2(4):041405. doi: 10.1117/1.NPh.2.4.041405. Epub 2015 Jun 22.

32.

Optogenetic stimulation of GABA neurons can decrease local neuronal activity while increasing cortical blood flow.

Anenberg E, Chan AW, Xie Y, LeDue JM, Murphy TH.

J Cereb Blood Flow Metab. 2015 Oct;35(10):1579-86. doi: 10.1038/jcbfm.2015.140. Epub 2015 Jun 17.

33.

Two-Photon Imaging of Neuronal Structural Plasticity in Mice during and after Ischemia.

Murphy TH.

Cold Spring Harb Protoc. 2015 Jun 1;2015(6):548-57. doi: 10.1101/pdb.prot087486.

PMID:
26034310
34.

A mouse model of small-vessel disease that produces brain-wide-identified microocclusions and regionally selective neuronal injury.

Silasi G, She J, Boyd JD, Xue S, Murphy TH.

J Cereb Blood Flow Metab. 2015 May;35(5):734-8. doi: 10.1038/jcbfm.2015.8. Epub 2015 Feb 18.

35.

Optogenetic mapping after stroke reveals network-wide scaling of functional connections and heterogeneous recovery of the peri-infarct.

Lim DH, LeDue JM, Mohajerani MH, Murphy TH.

J Neurosci. 2014 Dec 3;34(49):16455-66. doi: 10.1523/JNEUROSCI.3384-14.2014. Erratum in: J Neurosci. 2015 Jun 17;35(24):9247.

36.
38.

Stroke and the connectome: how connectivity guides therapeutic intervention.

Silasi G, Murphy TH.

Neuron. 2014 Sep 17;83(6):1354-68. doi: 10.1016/j.neuron.2014.08.052. Review. Erratum in: Neuron. 2014 Oct 22;84(2):511.

39.

Removing the brakes on post-stroke plasticity drives recovery from the intact hemisphere and spinal cord.

Silasi G, Murphy TH.

Brain. 2014 Mar;137(Pt 3):648-50. doi: 10.1093/brain/awu016. No abstract available.

PMID:
24549809
40.

Motor maps and the cortical control of movement.

Harrison TC, Murphy TH.

Curr Opin Neurobiol. 2014 Feb;24(1):88-94. doi: 10.1016/j.conb.2013.08.018. Epub 2013 Sep 21. Review.

PMID:
24492084
41.

Ministrokes in channelrhodopsin-2 transgenic mice reveal widespread deficits in motor output despite maintenance of cortical neuronal excitability.

Anenberg E, Arstikaitis P, Niitsu Y, Harrison TC, Boyd JD, Hilton BJ, Tetzlaff W, Murphy TH.

J Neurosci. 2014 Jan 22;34(4):1094-104. doi: 10.1523/JNEUROSCI.1442-13.2014.

42.

Spontaneous cortical activity alternates between motifs defined by regional axonal projections.

Mohajerani MH, Chan AW, Mohsenvand M, LeDue J, Liu R, McVea DA, Boyd JD, Wang YT, Reimers M, Murphy TH.

Nat Neurosci. 2013 Oct;16(10):1426-35. doi: 10.1038/nn.3499. Epub 2013 Aug 25.

43.

Improved methods for chronic light-based motor mapping in mice: automated movement tracking with accelerometers, and chronic EEG recording in a bilateral thin-skull preparation.

Silasi G, Boyd JD, Ledue J, Murphy TH.

Front Neural Circuits. 2013 Jul 25;7:123. doi: 10.3389/fncir.2013.00123. eCollection 2013.

44.

Displacement of sensory maps and disorganization of motor cortex after targeted stroke in mice.

Harrison TC, Silasi G, Boyd JD, Murphy TH.

Stroke. 2013 Aug;44(8):2300-6. doi: 10.1161/STROKEAHA.113.001272. Epub 2013 Jun 6.

PMID:
23743973
45.

Resistance of optogenetically evoked motor function to global ischemia and reperfusion in mouse in vivo.

Xie Y, Chen S, Anenberg E, Murphy TH.

J Cereb Blood Flow Metab. 2013 Aug;33(8):1148-52. doi: 10.1038/jcbfm.2013.89. Epub 2013 Jun 5.

46.

Optogenetic approaches for functional mouse brain mapping.

Lim DH, Ledue J, Mohajerani MH, Vanni MP, Murphy TH.

Front Neurosci. 2013 Apr 10;7:54. doi: 10.3389/fnins.2013.00054. eCollection 2013.

47.

Towards a circuit mechanism for movement tuning in motor cortex.

Harrison TC, Murphy TH.

Front Neural Circuits. 2013 Jan 18;6:127. doi: 10.3389/fncir.2012.00127. eCollection 2012.

49.

Voltage-sensitive dye imaging reveals dynamic spatiotemporal properties of cortical activity after spontaneous muscle twitches in the newborn rat.

McVea DA, Mohajerani MH, Murphy TH.

J Neurosci. 2012 Aug 8;32(32):10982-94. doi: 10.1523/JNEUROSCI.1322-12.2012.

50.

Distinct cortical circuit mechanisms for complex forelimb movement and motor map topography.

Harrison TC, Ayling OG, Murphy TH.

Neuron. 2012 Apr 26;74(2):397-409. doi: 10.1016/j.neuron.2012.02.028.

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