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Impact of Pseudomonas aeruginosa Isolation on Mortality and Outcomes in an Outpatient Chronic Obstructive Pulmonary Disease Cohort.

Jacobs DM, Ochs-Balcom HM, Noyes K, Zhao J, Leung WY, Pu CY, Murphy TF, Sethi S.

Open Forum Infect Dis. 2020 Jan 4;7(1):ofz546. doi: 10.1093/ofid/ofz546. eCollection 2020 Jan.


ReVac: a reverse vaccinology computational pipeline for prioritization of prokaryotic protein vaccine candidates.

D'Mello A, Ahearn CP, Murphy TF, Tettelin H.

BMC Genomics. 2019 Dec 16;20(1):981. doi: 10.1186/s12864-019-6195-y.


The Vatican on gender theory and the responsibilities of medicine.

Murphy TF.

Bioethics. 2019 Nov;33(9):981-983. doi: 10.1111/bioe.12669. No abstract available.


Discovery and Contribution of Nontypeable Haemophilus influenzae NTHI1441 to Human Respiratory Epithelial Cell Invasion.

Ahearn CP, Kirkham C, Chaves LD, Kong Y, Pettigrew MM, Murphy TF.

Infect Immun. 2019 Oct 18;87(11). pii: e00462-19. doi: 10.1128/IAI.00462-19. Print 2019 Nov.


Biogenetic ties and parent-child relationships: The misplaced critique.

Murphy TF.

Bioethics. 2019 Nov;33(9):1029-1034. doi: 10.1111/bioe.12621. Epub 2019 Aug 6.


Extending Health Insurance for Body Modifications for Gender Transitions.

Murphy TF.

Am J Bioeth. 2018 Dec;18(12):19-21. doi: 10.1080/15265161.2018.1531164. No abstract available.


The Laminin Interactome: A Multifactorial Laminin-Binding Strategy by Nontypeable Haemophilus influenzae for Effective Adherence and Colonization.

Su YC, Mattsson E, Singh B, Jalalvand F, Murphy TF, Riesbeck K.

J Infect Dis. 2019 Aug 9;220(6):1049-1060. doi: 10.1093/infdis/jiz217.


Small-Molecule Inhibitors of Haemophilus influenzae IgA1 Protease.

Shehaj L, Choudary SK, Makwana KM, Gallo MC, Murphy TF, Kritzer JA.

ACS Infect Dis. 2019 Jul 12;5(7):1129-1138. doi: 10.1021/acsinfecdis.9b00004. Epub 2019 May 3.


Adolescents and Body Modification for Gender Identity Expression.

Murphy TF.

Med Law Rev. 2019 Nov 1;27(4):623-639. doi: 10.1093/medlaw/fwz006.


Closed Complete Genome Sequences of Two Nontypeable Haemophilus influenzae Strains Containing Novel modA Alleles from the Sputum of Patients with Chronic Obstructive Pulmonary Disease.

Atack JM, Murphy TF, Bakaletz LO, Seib KL, Jennings MP.

Microbiol Resour Announc. 2018 Jul 19;7(2). pii: e00821-18. doi: 10.1128/MRA.00821-18. eCollection 2018 Jul.


Persistence of Moraxella catarrhalis in Chronic Obstructive Pulmonary Disease and Regulation of the Hag/MID Adhesin.

Murphy TF, Brauer AL, Pettigrew MM, LaFontaine ER, Tettelin H.

J Infect Dis. 2019 Apr 16;219(9):1448-1455. doi: 10.1093/infdis/jiy680.


Differential distribution of IgA-protease genotypes in mucosal and invasive isolates of Haemophilus influenzae in Sweden.

Resman F, Manat G, Lindh V, Murphy TF, Riesbeck K.

BMC Infect Dis. 2018 Nov 22;18(1):592. doi: 10.1186/s12879-018-3464-3.


Moraxella catarrhalis Restriction-Modification Systems Are Associated with Phylogenetic Lineage and Disease.

Blakeway LV, Tan A, Lappan R, Ariff A, Pickering JL, Peacock CS, Blyth CC, Kahler CM, Chang BJ, Lehmann D, Kirkham LS, Murphy TF, Jennings MP, Bakaletz LO, Atack JM, Peak IR, Seib KL.

Genome Biol Evol. 2018 Nov 1;10(11):2932-2946. doi: 10.1093/gbe/evy226.


Lower Airway Bacterial Colonization Patterns and Species-Specific Interactions in Chronic Obstructive Pulmonary Disease.

Jacobs DM, Ochs-Balcom HM, Zhao J, Murphy TF, Sethi S.

J Clin Microbiol. 2018 Sep 25;56(10). pii: e00330-18. doi: 10.1128/JCM.00330-18. Print 2018 Oct.


Changes in IgA Protease Expression Are Conferred by Changes in Genomes during Persistent Infection by Nontypeable Haemophilus influenzae in Chronic Obstructive Pulmonary Disease.

Gallo MC, Kirkham C, Eng S, Bebawee RS, Kong Y, Pettigrew MM, Tettelin H, Murphy TF.

Infect Immun. 2018 Jul 23;86(8). pii: e00313-18. doi: 10.1128/IAI.00313-18. Print 2018 Aug.


So not mothers: responsibility for surrogate orphans.

Parks JA, Murphy TF.

J Med Ethics. 2018 Aug;44(8):551-554. doi: 10.1136/medethics-2017-104331. Epub 2018 Apr 12.


Early Hospital Readmissions after an Acute Exacerbation of Chronic Obstructive Pulmonary Disease in the Nationwide Readmissions Database.

Jacobs DM, Noyes K, Zhao J, Gibson W, Murphy TF, Sethi S, Ochs-Balcom HM.

Ann Am Thorac Soc. 2018 Jul;15(7):837-845. doi: 10.1513/AnnalsATS.201712-913OC.


Haemophilus influenzae genome evolution during persistence in the human airways in chronic obstructive pulmonary disease.

Pettigrew MM, Ahearn CP, Gent JF, Kong Y, Gallo MC, Munro JB, D'Mello A, Sethi S, Tettelin H, Murphy TF.

Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):E3256-E3265. doi: 10.1073/pnas.1719654115. Epub 2018 Mar 19.


Prescription Opioid Dependence in Western New York: Using Data Analytics to Find an Answer to the Opioid Epidemic.

Sinha S, Burstein GR, Leonard KE, Murphy TF, Elkin PL.

Stud Health Technol Inform. 2017;245:594-598.


First Come, First Served in the Intensive Care Unit: Always?

Fleck LM, Murphy TF.

Camb Q Healthc Ethics. 2018 Jan;27(1):52-61. doi: 10.1017/S0963180117000391.


Mapping Protective Regions on a Three-Dimensional Model of the Moraxella catarrhalis Vaccine Antigen Oligopeptide Permease A.

Perez AC, Johnson A, Chen Z, Wilding GE, Malkowski MG, Murphy TF.

Infect Immun. 2018 Feb 20;86(3). pii: e00652-17. doi: 10.1128/IAI.00652-17. Print 2018 Mar.


Azithromycin Pharmacodynamics against Persistent Haemophilus influenzae in Chronic Obstructive Pulmonary Disease.

Tsuji BT, Fisher J, Boadi-Yeboah R, Holden PN, Sethi S, Pettigrew MM, Murphy TF.

Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e01995-17. doi: 10.1128/AAC.01995-17. Print 2018 Feb.


Bioethics, children, and the environment.

Murphy TF.

Bioethics. 2018 Jan;32(1):3-9. doi: 10.1111/bioe.12386. Epub 2017 Sep 5.


A Moraxella catarrhalis vaccine to protect against otitis media and exacerbations of COPD: An update on current progress and challenges.

Perez AC, Murphy TF.

Hum Vaccin Immunother. 2017 Oct 3;13(10):2322-2331. doi: 10.1080/21645515.2017.1356951. Review.


Stringently Defined Otitis Prone Children Demonstrate Deficient Naturally Induced Mucosal Antibody Response to Moraxella catarrhalis Proteins.

Ren D, Murphy TF, Lafontaine ER, Pichichero ME.

Front Immunol. 2017 Aug 11;8:953. doi: 10.3389/fimmu.2017.00953. eCollection 2017.


Serum antibody response to Moraxella catarrhalis proteins in stringently defined otitis prone children.

Ren D, Almudevar AL, Murphy TF, Lafontaine ER, Campagnari AA, Luke-Marshall N, Pichichero ME.

Vaccine. 2019 Jul 26;37(32):4637-4645. doi: 10.1016/j.vaccine.2017.07.027. Epub 2017 Jul 26.


A Cation-Binding Surface Protein as a Vaccine Antigen To Prevent Moraxella catarrhalis Otitis Media and Infections in Chronic Obstructive Pulmonary Disease.

Murphy TF, Brauer AL, Johnson A, Wilding GE, Koszelak-Rosenblum M, Malkowski MG.

Clin Vaccine Immunol. 2017 Sep 5;24(9). pii: e00130-17. doi: 10.1128/CVI.00130-17. Print 2017 Sep.


Pathways to genetic parenthood for same-sex couples.

Murphy TF.

J Med Ethics. 2018 Dec;44(12):823-824. doi: 10.1136/medethics-2017-104291. Epub 2017 Apr 27.


Insights on persistent airway infection by non-typeable Haemophilus influenzae in chronic obstructive pulmonary disease.

Ahearn CP, Gallo MC, Murphy TF.

Pathog Dis. 2017 Jun 1;75(4). doi: 10.1093/femspd/ftx042. Review.


Panel 6: Vaccines.

Pettigrew MM, Alderson MR, Bakaletz LO, Barenkamp SJ, Hakansson AP, Mason KM, Nokso-Koivisto J, Patel J, Pelton SI, Murphy TF.

Otolaryngol Head Neck Surg. 2017 Apr;156(4_suppl):S76-S87. doi: 10.1177/0194599816632178. Review.


Sex before the State: Civic Sex, Reproductive Innovations, and Gendered Parental Identity.

Murphy TF.

Camb Q Healthc Ethics. 2017 Apr;26(2):267-277. doi: 10.1017/S0963180116000864.


Potential impact of a Moraxella catarrhalis vaccine in COPD.

Perez AC, Murphy TF.

Vaccine. 2019 Sep 3;37(37):5551-5558. doi: 10.1016/j.vaccine.2016.12.066. Epub 2017 Feb 6. Review.


Antimicrobial activity of antisense peptide-peptide nucleic acid conjugates against non-typeable Haemophilus influenzae in planktonic and biofilm forms.

Otsuka T, Brauer AL, Kirkham C, Sully EK, Pettigrew MM, Kong Y, Geller BL, Murphy TF.

J Antimicrob Chemother. 2017 Jan;72(1):137-144. Epub 2016 Sep 28.


Should fertility clinics divest themselves of pornography?

Murphy TF.

Reprod Biomed Soc Online. 2016 Dec 13;3:30-35. doi: 10.1016/j.rbms.2016.10.003. eCollection 2016 Dec.


Should Mental Health Screening and Psychotherapy Be Required Prior to Body Modification for Gender Expression?

Murphy TF.

AMA J Ethics. 2016 Nov 1;18(11):1079-1085. doi: 10.1001/journalofethics.2016.18.11.ecas2-1611.


Comparative Genomic Analysis of Haemophilus haemolyticus and Nontypeable Haemophilus influenzae and a New Testing Scheme for Their Discrimination.

Hu F, Rishishwar L, Sivadas A, Mitchell GJ, Jordan IK, Murphy TF, Gilsdorf JR, Mayer LW, Wang X.

J Clin Microbiol. 2016 Dec;54(12):3010-3017. Epub 2016 Oct 5.


What Justifies a Future with Humans in It?

Murphy TF.

Bioethics. 2016 Nov;30(9):751-758. doi: 10.1111/bioe.12290. Epub 2016 Sep 26.


ATP-Binding Cassette (ABC) Transporters of the Human Respiratory Tract Pathogen, Moraxella catarrhalis: Role in Virulence.

Murphy TF, Brauer AL, Johnson A, Kirkham C.

PLoS One. 2016 Jul 8;11(7):e0158689. doi: 10.1371/journal.pone.0158689. eCollection 2016.


Sulfate-binding protein, CysP, is a candidate vaccine antigen of Moraxella catarrhalis.

Murphy TF, Kirkham C, Johnson A, Brauer AL, Koszelak-Rosenblum M, Malkowski MG.

Vaccine. 2016 Jul 19;34(33):3855-61. doi: 10.1016/j.vaccine.2016.05.045. Epub 2016 Jun 14.


Effect of Fluoroquinolones and Macrolides on Eradication and Resistance of Haemophilus influenzae in Chronic Obstructive Pulmonary Disease.

Pettigrew MM, Tsuji BT, Gent JF, Kong Y, Holden PN, Sethi S, Murphy TF.

Antimicrob Agents Chemother. 2016 Jun 20;60(7):4151-8. doi: 10.1128/AAC.00301-16. Print 2016 Jul.


Comparative Analyses of the Lipooligosaccharides from Nontypeable Haemophilus influenzae and Haemophilus haemolyticus Show Differences in Sialic Acid and Phosphorylcholine Modifications.

Post DM, Ketterer MR, Coffin JE, Reinders LM, Munson RS Jr, Bair T, Murphy TF, Foster ED, Gibson BW, Apicella MA.

Infect Immun. 2016 Jan 4;84(3):765-74. doi: 10.1128/IAI.01185-15.


The Vaccine Candidate Substrate Binding Protein SBP2 Plays a Key Role in Arginine Uptake, Which Is Required for Growth of Moraxella catarrhalis.

Otsuka T, Kirkham C, Brauer A, Koszelak-Rosenblum M, Malkowski MG, Murphy TF.

Infect Immun. 2015 Nov 23;84(2):432-8. doi: 10.1128/IAI.00799-15. Print 2016 Feb.


Serum antibody response to Moraxella catarrhalis proteins OMP CD, OppA, Msp22, Hag, and PilA2 after nasopharyngeal colonization and acute otitis media in children.

Ren D, Almudevar AL, Murphy TF, Lafontaine ER, Campagnari AA, Luke-Marshall N, Casey JR, Pichichero ME.

Vaccine. 2015 Oct 26;33(43):5809-5814. doi: 10.1016/j.vaccine.2015.09.023. Epub 2015 Sep 21.


The Tortoise Transformation as a Prospect for Life Extension.

Murphy TF.

J Bioeth Inq. 2015 Dec;12(4):645-9. doi: 10.1007/s11673-015-9645-5. Epub 2015 Jul 2.


Expression of the Oligopeptide Permease Operon of Moraxella catarrhalis Is Regulated by Temperature and Nutrient Availability.

Jones MM, Murphy TF.

Infect Immun. 2015 Sep;83(9):3497-505. doi: 10.1128/IAI.00597-15. Epub 2015 Jun 22.


LGBT People and the Work Ahead in Bioethics.

Murphy TF.

Bioethics. 2015 Jul;29(6):ii-v. doi: 10.1111/bioe.12168. No abstract available.


Expression of IgA Proteases by Haemophilus influenzae in the Respiratory Tract of Adults With Chronic Obstructive Pulmonary Disease.

Murphy TF, Kirkham C, Jones MM, Sethi S, Kong Y, Pettigrew MM.

J Infect Dis. 2015 Dec 1;212(11):1798-805. doi: 10.1093/infdis/jiv299. Epub 2015 May 20.

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