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Items: 45


Knockout of Dual-Specificity Protein Phosphatase 5 Protects Against Hypertension-Induced Renal Injury.

Zhang C, He X, Murphy SR, Zhang H, Wang S, Ge Y, Gao W, Williams JM, Geurts AM, Roman RJ, Fan F.

J Pharmacol Exp Ther. 2019 Aug;370(2):206-217. doi: 10.1124/jpet.119.258954. Epub 2019 May 22.


Arachidonic acid metabolites of CYP4A and CYP4F are altered in women with preeclampsia.

Plenty NL, Faulkner JL, Cotton J, Spencer SK, Wallace K, LaMarca B, Murphy SR.

Prostaglandins Other Lipid Mediat. 2018 May;136:15-22. doi: 10.1016/j.prostaglandins.2018.03.001. Epub 2018 Mar 26.


β-Adrenergic Inhibition Prevents Action Potential and Calcium Handling Changes during Regional Myocardial Ischemia.

Murphy SR, Wang L, Wang Z, Domondon P, Lang D, Habecker BA, Myles RC, Ripplinger CM.

Front Physiol. 2017 Aug 28;8:630. doi: 10.3389/fphys.2017.00630. eCollection 2017.


Evaluating the landscape of fear between apex predatory sharks and mobile sea turtles across a large dynamic seascape.

Hammerschlag N, Broderick AC, Coker JW, Coyne MS, Dodd M, Frick MG, Godfrey MH, Godley BJ, Griffin DB, Hartog K, Murphy SR, Murphy TM, Nelson ER, Williams KL, Witt MJ, Hawkes LA.

Ecology. 2015 Aug;96(8):2117-26.


Emerging drugs for preeclampsia--the endothelium as a target.

Sasser JM, Murphy SR, Granger JP.

Expert Opin Emerg Drugs. 2015;20(4):527-30. doi: 10.1517/14728214.2015.1062875. Epub 2015 Jul 3. Review.


Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage.

Shibuya Y, Niu Z, Bryleva EY, Harris BT, Murphy SR, Kheirollah A, Bowen ZD, Chang CCY, Chang TY.

Neurobiol Aging. 2015 Jul;36(7):2248-2259. doi: 10.1016/j.neurobiolaging.2015.04.002. Epub 2015 Apr 7.


Regulation of soluble fms-like tyrosine kinase-1 production in response to placental ischemia/hypoxia: role of angiotensin II.

Murphy SR, Cockrell K.

Physiol Rep. 2015 Feb 25;3(2). pii: e12310. doi: 10.14814/phy2.12310. Print 2015 Feb 1.


Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4A1 transgenic Dahl salt-sensitive rat.

Fan F, Geurts AM, Murphy SR, Pabbidi MR, Jacob HJ, Roman RJ.

Am J Physiol Regul Integr Comp Physiol. 2015 Mar 1;308(5):R379-90. doi: 10.1152/ajpregu.00256.2014. Epub 2014 Dec 24.


Placental ischemia in pregnant rats impairs cerebral blood flow autoregulation and increases blood-brain barrier permeability.

Warrington JP, Fan F, Murphy SR, Roman RJ, Drummond HA, Granger JP, Ryan MJ.

Physiol Rep. 2014 Aug 28;2(8). pii: e12134. doi: 10.14814/phy2.12134. Print 2014 Aug 1.


Ozone-induced airway epithelial cell death, the neurokinin-1 receptor pathway, and the postnatal developing lung.

Murphy SR, Oslund KL, Hyde DM, Miller LA, Van Winkle LS, Schelegle ES.

Am J Physiol Lung Cell Mol Physiol. 2014 Sep 15;307(6):L471-81. doi: 10.1152/ajplung.00324.2013. Epub 2014 Jul 25.


Role of 20-HETE in the impaired myogenic and TGF responses of the Af-Art of Dahl salt-sensitive rats.

Ge Y, Murphy SR, Fan F, Williams JM, Falck JR, Liu R, Roman RJ.

Am J Physiol Renal Physiol. 2014 Sep 1;307(5):F509-15. doi: 10.1152/ajprenal.00273.2014. Epub 2014 Jul 9.


Acat1 knockdown gene therapy decreases amyloid-β in a mouse model of Alzheimer's disease.

Murphy SR, Chang CC, Dogbevia G, Bryleva EY, Bowen Z, Hasan MT, Chang TY.

Mol Ther. 2013 Aug;21(8):1497-506. doi: 10.1038/mt.2013.118. Epub 2013 Jun 18.


Fetal exposure of rhesus macaques to bisphenol a alters cellular development of the conducting airway by changing epithelial secretory product expression.

Van Winkle LS, Murphy SR, Boetticher MV, VandeVoort CA.

Environ Health Perspect. 2013 Aug;121(8):912-8. doi: 10.1289/ehp.1206064. Epub 2013 Jun 11.


Ozone exposure alters serotonin and serotonin receptor expression in the developing lung.

Murphy SR, Schelegle ES, Miller LA, Hyde DM, Van Winkle LS.

Toxicol Sci. 2013 Jul;134(1):168-79. doi: 10.1093/toxsci/kft090. Epub 2013 Apr 9.


Endogenously produced 20-HETE modulates myogenic and TGF response in microperfused afferent arterioles.

Ge Y, Murphy SR, Lu Y, Falck J, Liu R, Roman RJ.

Prostaglandins Other Lipid Mediat. 2013 Apr-May;102-103:42-8. doi: 10.1016/j.prostaglandins.2013.03.001. Epub 2013 Mar 14.


The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteins.

Poirier S, Mayer G, Murphy SR, Garver WS, Chang TY, Schu P, Seidah NG.

Traffic. 2013 Apr;14(4):458-69. doi: 10.1111/tra.12046. Epub 2013 Feb 20.


Control of soluble fms-like tyrosine-1 (sFlt-1) production response to placental ischemia/hypoxia: role of tumor necrosis factor-α.

Murphy SR, LaMarca BB, Parrish M, Cockrell K, Granger JP.

Am J Physiol Regul Integr Comp Physiol. 2013 Jan 15;304(2):R130-5. doi: 10.1152/ajpregu.00069.2012. Epub 2012 Nov 28.


Postnatal exposure history and airways: oxidant stress responses in airway explants.

Murphy SR, Schelegle ES, Edwards PC, Miller LA, Hyde DM, Van Winkle LS.

Am J Respir Cell Mol Biol. 2012 Dec;47(6):815-23. doi: 10.1165/rcmb.2012-0110OC. Epub 2012 Sep 6.


Renoprotective effects of anti-TGF-β antibody and antihypertensive therapies in Dahl S rats.

Murphy SR, Dahly-Vernon AJ, Dunn KM, Chen CC, Ledbetter SR, Williams JM, Roman RJ.

Am J Physiol Regul Integr Comp Physiol. 2012 Jul 1;303(1):R57-69. doi: 10.1152/ajpregu.00263.2011. Epub 2012 Apr 25.


L-arginine supplementation abolishes the blood pressure and endothelin response to chronic increases in plasma sFlt-1 in pregnant rats.

Murphy SR, LaMarca B, Cockrell K, Arany M, Granger JP.

Am J Physiol Regul Integr Comp Physiol. 2012 Jan 15;302(2):R259-63. doi: 10.1152/ajpregu.00319.2011. Epub 2011 Nov 9.


Subchronic toxicity of S-111-S-WB in Sprague Dawley rats.

Mertens JJ, Sved DW, Marit GB, Myers NR, Stetson PL, Murphy SR, Schmit B, Shinohara M, Farr CH.

Int J Toxicol. 2010 Jul;29(4):358-71. doi: 10.1177/1091581810370372. Epub 2010 Jun 2.


The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancy.

Parrish MR, Murphy SR, Rutland S, Wallace K, Wenzel K, Wallukat G, Keiser S, Ray LF, Dechend R, Martin JN, Granger JP, LaMarca B.

Am J Hypertens. 2010 Aug;23(8):911-6. doi: 10.1038/ajh.2010.70. Epub 2010 Apr 29.


Neuronal cholesterol esterification by ACAT1 in Alzheimer's disease.

Chang TY, Chang CC, Bryleva E, Rogers MA, Murphy SR.

IUBMB Life. 2010 Apr;62(4):261-7. doi: 10.1002/iub.305. Review.


Role of endothelin in mediating soluble fms-like tyrosine kinase 1-induced hypertension in pregnant rats.

Murphy SR, LaMarca BB, Cockrell K, Granger JP.

Hypertension. 2010 Feb;55(2):394-8. doi: 10.1161/HYPERTENSIONAHA.109.141473. Epub 2009 Dec 21.


Postnatal lung development of rhesus monkey airways: cellular expression of Clara cell secretory protein.

Coppens JT, Plopper CG, Murphy SR, Van Winkle LS.

Dev Dyn. 2009 Dec;238(12):3016-24. doi: 10.1002/dvdy.22132.


A simple parametric method for reducing sample sizes in gut passage time trials.

Rawsthorne J, Roshier DA, Murphy SR.

Ecology. 2009 Aug;90(8):2328-31.


Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1.

LaMarca B, Parrish M, Ray LF, Murphy SR, Roberts L, Glover P, Wallukat G, Wenzel K, Cockrell K, Martin JN Jr, Ryan MJ, Dechend R.

Hypertension. 2009 Oct;54(4):905-9. doi: 10.1161/HYPERTENSIONAHA.109.137935. Epub 2009 Aug 24.


Transport of LDL-derived cholesterol from the NPC1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex.

Urano Y, Watanabe H, Murphy SR, Shibuya Y, Geng Y, Peden AA, Chang CC, Chang TY.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16513-8. doi: 10.1073/pnas.0807450105. Epub 2008 Oct 22. Erratum in: Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19561.


The cotranslational maturation program for the type II membrane glycoprotein influenza neuraminidase.

Wang N, Glidden EJ, Murphy SR, Pearse BR, Hebert DN.

J Biol Chem. 2008 Dec 5;283(49):33826-37. doi: 10.1074/jbc.M806897200. Epub 2008 Oct 10.


Pathophysiology of hypertension in response to placental ischemia during pregnancy: a central role for endothelin?

LaMarca BD, Alexander BT, Gilbert JS, Ryan MJ, Sedeek M, Murphy SR, Granger JP.

Gend Med. 2008;5 Suppl A:S133-8. doi: 10.1016/j.genm.2008.03.013. Review.


Inflammatory cytokines in the pathophysiology of hypertension during preeclampsia.

LaMarca BD, Ryan MJ, Gilbert JS, Murphy SR, Granger JP.

Curr Hypertens Rep. 2007 Dec;9(6):480-5. Review.


Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction.

Gilbert JS, Ryan MJ, LaMarca BB, Sedeek M, Murphy SR, Granger JP.

Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H541-50. Epub 2007 Nov 30. Review.


An oral two-generation reproductive toxicity study of S-111-S-WB in rats.

Stump DG, Holson JF, Murphy SR, Farr CH, Schmit B, Shinohara M.

Reprod Toxicol. 2008 Jan;25(1):7-20. Epub 2007 Oct 7.


The toxicology of perfluorooctanoate.

Kennedy GL Jr, Butenhoff JL, Olsen GW, O'Connor JC, Seacat AM, Perkins RG, Biegel LB, Murphy SR, Farrar DG.

Crit Rev Toxicol. 2004 Jul-Aug;34(4):351-84. Review.


Two-generation reproduction and developmental neurotoxicity study with sodium chlorite in the rat.

Gill MW, Swanson MS, Murphy SR, Bailey GP.

J Appl Toxicol. 2000 Jul-Aug;20(4):291-303.


Determination of selected fate and aquatic toxicity characteristics of acrylic acid and a series of acrylic esters.

Staples CA, Murphy SR, McLaughlin JE, Leung HW, Cascieri TC, Farr CH.

Chemosphere. 2000 Jan;40(1):29-38.


Repeated dose toxicity study (28 days) in rats and mice with N-methylpyrrolidone (NMP).

Malek DE, Malley LA, Slone TW, Elliott GS, Kennedy GL, Mellert W, Deckardt K, Gembardt C, Hildebrand B, Murphy SR, Bower DB, Wright GA.

Drug Chem Toxicol. 1997 Feb-May;20(1-2):63-77.


Oncogenicity testing of 2-ethylhexanol in Fischer 344 rats and B6C3F1 mice.

Astill BD, Gingell R, Guest D, Hellwig J, Hodgson JR, Kuettler K, Mellert W, Murphy SR, Sielken RL Jr, Tyler TR.

Fundam Appl Toxicol. 1996 May;31(1):29-41.


Prechronic toxicity studies on 2-ethylhexanol in F334 rats and B6C3F1 mice.

Astill BD, Deckardt K, Gembardt C, Gingell R, Guest D, Hodgson JR, Mellert W, Murphy SR, Tyler TR.

Fundam Appl Toxicol. 1996 Jan;29(1):31-9.


Comparison of the maximum tolerated dose (MTD) dermal response in three strains of mice following repeated exposure to acrylic acid.

McLaughlin JE, Parno J, Garner FM, Clary JJ, Thomas WC, Murphy SR.

Food Chem Toxicol. 1995 Jun;33(6):507-13.


Differential passage time of mistletoe fruits through the gut of honeyeaters and flowerpeckers: effects on seedling establishment.

Murphy SR, Reid N, Yan Z, Venables WN.

Oecologia. 1993 Mar;93(2):171-176. doi: 10.1007/BF00317667.


The developmental toxicity of 2-ethylhexanol applied dermally to pregnant Fischer 344 rats.

Tyl RW, Fisher LC, Kubena MF, Vrbanic MA, Gingell R, Guest D, Hodgson JR, Murphy SR, Tyler TR, Astill BD.

Fundam Appl Toxicol. 1992 Aug;19(2):176-85.


"Myopathic" changes in chronically denervated muscle.

Drachman DB, Murphy SR, Nigam MP, Hills JR.

Arch Neurol. 1967 Jan;16(1):14-24. No abstract available.


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