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Items: 1 to 50 of 299

1.

Abnormal Newborn Screen in a WHIM Syndrome Infant.

Evans MO 2nd, McDermott DH, Murphy PM, Petersen MM.

J Clin Immunol. 2019 Sep 6. doi: 10.1007/s10875-019-00686-5. [Epub ahead of print] No abstract available.

PMID:
31493092
2.

Case Report: Ocular toxoplasmosis in a WHIM syndrome immunodeficiency patient.

McDermott DH, Heusinkveld LE, Zein WM, Sen HN, Marquesen MM, Parta M, Rosenzweig SD, Fahle GA, Keller MD, Wiley HE, Murphy PM.

Version 2. F1000Res. 2019 Jan 2 [revised 2019 Jan 1];8:2. doi: 10.12688/f1000research.16825.2. eCollection 2019.

3.

WHIM Syndrome: from Pathogenesis Towards Personalized Medicine and Cure.

Heusinkveld LE, Majumdar S, Gao JL, McDermott DH, Murphy PM.

J Clin Immunol. 2019 Aug;39(6):532-556. doi: 10.1007/s10875-019-00665-w. Epub 2019 Jul 16.

PMID:
31313072
4.

ACR Ultrasound Liver Reporting and Data System: Multicenter Assessment of Clinical Performance at One Year.

Millet JD, Kamaya A, Choi HH, Dahiya N, Murphy PM, Naveed MZ, O'Boyle M, Parra LA, Perez MG, Pirmoazen AM, Rodgers SK, Wasnik AP, Maturen KE.

J Am Coll Radiol. 2019 Jun 4. pii: S1546-1440(19)30607-6. doi: 10.1016/j.jacr.2019.05.020. [Epub ahead of print]

PMID:
31173745
5.

Image Annotation by Eye Tracking: Accuracy and Precision of Centerlines of Obstructed Small-Bowel Segments Placed Using Eye Trackers.

Lucas A, Wang K, Santillan C, Hsiao A, Sirlin CB, Murphy PM.

J Digit Imaging. 2019 Oct;32(5):855-864. doi: 10.1007/s10278-018-0169-5.

PMID:
31144146
6.

Plerixafor for the Treatment of WHIM Syndrome. Reply.

McDermott DH, Murphy PM.

N Engl J Med. 2019 Apr 18;380(16):e25. doi: 10.1056/NEJMc1901646. No abstract available.

PMID:
30995388
7.

IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus.

Spolski R, West EE, Li P, Veenbergen S, Yung S, Kazemian M, Oh J, Yu ZX, Freeman AF, Holland SM, Murphy PM, Leonard WJ.

Elife. 2019 Apr 16;8. pii: e45501. doi: 10.7554/eLife.45501.

8.

Low-Level Parasite Persistence Drives Vasculitis and Myositis in Skeletal Muscle of Mice Chronically Infected with Trypanosoma cruzi.

Weaver JD, Hoffman VJ, Roffe E, Murphy PM.

Infect Immun. 2019 May 21;87(6). pii: e00081-19. doi: 10.1128/IAI.00081-19. Print 2019 Jun.

PMID:
30936158
9.
10.

Plerixafor for the Treatment of WHIM Syndrome.

McDermott DH, Pastrana DV, Calvo KR, Pittaluga S, Velez D, Cho E, Liu Q, Trout HH 3rd, Neves JF, Gardner PJ, Bianchi DA, Blair EA, Landon EM, Silva SL, Buck CB, Murphy PM.

N Engl J Med. 2019 Jan 10;380(2):163-170. doi: 10.1056/NEJMoa1808575.

11.

Adaptive Immunodeficiency in WHIM Syndrome.

Majumdar S, Murphy PM.

Int J Mol Sci. 2018 Dec 20;20(1). pii: E3. doi: 10.3390/ijms20010003. Review.

12.

WHIM syndrome: Immunopathogenesis, treatment and cure strategies.

McDermott DH, Murphy PM.

Immunol Rev. 2019 Jan;287(1):91-102. doi: 10.1111/imr.12719. Review.

PMID:
30565238
13.

Metagenomic Discovery of 83 New Human Papillomavirus Types in Patients with Immunodeficiency.

Pastrana DV, Peretti A, Welch NL, Borgogna C, Olivero C, Badolato R, Notarangelo LD, Gariglio M, FitzGerald PC, McIntosh CE, Reeves J, Starrett GJ, Bliskovsky V, Velez D, Brownell I, Yarchoan R, Wyvill KM, Uldrick TS, Maldarelli F, Lisco A, Sereti I, Gonzalez CM, Androphy EJ, McBride AA, Van Doorslaer K, Garcia F, Dvoretzky I, Liu JS, Han J, Murphy PM, McDermott DH, Buck CB.

mSphere. 2018 Dec 12;3(6). pii: e00645-18. doi: 10.1128/mSphereDirect.00645-18.

14.

Chemokine Subversion by Human Herpesviruses.

Pontejo SM, Murphy PM, Pease JE.

J Innate Immun. 2018;10(5-6):465-478. doi: 10.1159/000492161. Epub 2018 Aug 30. Review.

15.

Cxcr4-haploinsufficient bone marrow transplantation corrects leukopenia in an unconditioned WHIM syndrome model.

Gao JL, Yim E, Siwicki M, Yang A, Liu Q, Azani A, Owusu-Ansah A, McDermott DH, Murphy PM.

J Clin Invest. 2018 Aug 1;128(8):3312-3318. doi: 10.1172/JCI120375. Epub 2018 Jun 25.

16.

Multisystem multitasking by CXCL12 and its receptors CXCR4 and ACKR3.

Murphy PM, Heusinkveld L.

Cytokine. 2018 Sep;109:2-10. doi: 10.1016/j.cyto.2017.12.022. Epub 2018 Feb 15. Review.

17.

Mechanisms of Sustained Neutrophilia in Patient WHIM-09, Cured of WHIM Syndrome by Chromothripsis.

Liu Q, Li Z, Y Yang A, Gao JL, S Velez D, J Cho E, McDermott DH, Murphy PM.

J Clin Immunol. 2018 Jan;38(1):77-87. doi: 10.1007/s10875-017-0457-8. Epub 2017 Nov 24.

18.

A novel HFO-based method for unsupervised localization of the seizure onset zone in drug-resistant epilepsy.

Murphy PM, von Paternos AJ, Santaniello S.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:1054-1057. doi: 10.1109/EMBC.2017.8037008.

PMID:
29060055
19.

Pathogenesis, diagnosis and therapeutic strategies in WHIM syndrome immunodeficiency.

Heusinkveld LE, Yim E, Yang A, Azani AB, Liu Q, Gao JL, McDermott DH, Murphy PM.

Expert Opin Orphan Drugs. 2017;5(10):813-825. doi: 10.1080/21678707.2017.1375403. Epub 2017 Sep 25.

20.

Chemokines encoded by herpesviruses.

Pontejo SM, Murphy PM.

J Leukoc Biol. 2017 Nov;102(5):1199-1217. doi: 10.1189/jlb.4RU0417-145RR. Epub 2017 Aug 28. Review.

21.

Biochemical and biophysical characterization of cytokine-like protein 1 (CYTL1).

Tomczak A, Singh K, Gittis AG, Lee J, Garboczi DN, Murphy PM.

Cytokine. 2017 Aug;96:238-246. doi: 10.1016/j.cyto.2017.04.023. Epub 2017 May 4.

22.

Two glycosaminoglycan-binding domains of the mouse cytomegalovirus-encoded chemokine MCK-2 are critical for oligomerization of the full-length protein.

Pontejo SM, Murphy PM.

J Biol Chem. 2017 Jun 9;292(23):9613-9626. doi: 10.1074/jbc.M117.785121. Epub 2017 Apr 21.

23.

WHIM Syndrome Caused by Waldenström's Macroglobulinemia-Associated Mutation CXCR4 (L329fs).

Liu Q, Pan C, Lopez L, Gao J, Velez D, Anaya-O'Brien S, Ulrick J, Littel P, Corns JS, Ellenburg DT, Malech HL, Murphy PM, McDermott DH.

J Clin Immunol. 2016 May;36(4):397-405. doi: 10.1007/s10875-016-0276-3. Epub 2016 Apr 8.

PMID:
27059040
24.

CXCR1 Regulates Pulmonary Anti-Pseudomonas Host Defense.

Carevic M, Öz H, Fuchs K, Laval J, Schroth C, Frey N, Hector A, Bilich T, Haug M, Schmidt A, Autenrieth SE, Bucher K, Beer-Hammer S, Gaggar A, Kneilling M, Benarafa C, Gao JL, Murphy PM, Schwarz S, Moepps B, Hartl D.

J Innate Immun. 2016;8(4):362-73. doi: 10.1159/000444125. Epub 2016 Mar 8.

25.
26.

Trypanosoma cruzi Causes Paralyzing Systemic Necrotizing Vasculitis Driven by Pathogen-Specific Type I Immunity in Mice.

Roffê E, Marino APMP, Weaver J, Wan W, de Araújo FF, Hoffman V, Santiago HC, Murphy PM.

Infect Immun. 2016 Mar 24;84(4):1123-1136. doi: 10.1128/IAI.01497-15. Print 2016 Apr.

27.

CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.

Swamydas M, Gao JL, Break TJ, Johnson MD, Jaeger M, Rodriguez CA, Lim JK, Green NM, Collar AL, Fischer BG, Lee CC, Perfect JR, Alexander BD, Kullberg BJ, Netea MG, Murphy PM, Lionakis MS.

Sci Transl Med. 2016 Jan 20;8(322):322ra10. doi: 10.1126/scitranslmed.aac7718.

28.

Chromothriptic cure of WHIM syndrome: Implications for bone marrow transplantation.

McDermott DH, Gao JL, Murphy PM.

Rare Dis. 2015 Aug 11;3(1):e1073430. doi: 10.1080/21675511.2015.1073430. eCollection 2015.

29.

Pre-treatment of allogeneic bone marrow recipients with the CXCR4 antagonist AMD3100 transiently enhances hematopoietic chimerism without promoting donor-specific skin allograft tolerance.

Li Z, Xu X, Weiss ID, Jacobson O, Murphy PM.

Transpl Immunol. 2015 Oct;33(2):125-9. doi: 10.1016/j.trim.2015.07.003. Epub 2015 Jul 21.

30.

Viral Chemokine Receptors.

Murphy PM.

Front Immunol. 2015 Jun 5;6:281. doi: 10.3389/fimmu.2015.00281. eCollection 2015. Review. No abstract available.

31.

Characterization of chemokine and chemokine receptor expression during Pneumocystis infection in healthy and immunodeficient mice.

Bishop LR, Lionakis MS, Sassi M, Murphy PM, Hu X, Huang da W, Sherman B, Qiu J, Yang J, Lempicki RA, Kovacs JA.

Microbes Infect. 2015 Sep;17(9):638-50. doi: 10.1016/j.micinf.2015.05.008. Epub 2015 Jun 5.

32.

Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity.

Dworzak J, Renvoisé B, Habchi J, Yates EV, Combadière C, Knowles TP, Dobson CM, Blackstone C, Paulsen O, Murphy PM.

PLoS One. 2015 Jun 3;10(6):e0127730. doi: 10.1371/journal.pone.0127730. eCollection 2015.

33.

An atypical addition to the chemokine receptor nomenclature: IUPHAR Review 15.

Bachelerie F, Graham GJ, Locati M, Mantovani A, Murphy PM, Nibbs R, Rot A, Sozzani S, Thelen M.

Br J Pharmacol. 2015 Aug;172(16):3945-9. doi: 10.1111/bph.13182. Epub 2015 Jun 26. Review.

34.

Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.

Wan W, Liu Q, Lionakis MS, Marino AP, Anderson SA, Swamydas M, Murphy PM.

Cardiovasc Res. 2015 Jun 1;106(3):478-87. doi: 10.1093/cvr/cvv124. Epub 2015 Apr 8.

35.

CXCR4 antagonist AMD3100 redistributes leukocytes from primary immune organs to secondary immune organs, lung, and blood in mice.

Liu Q, Li Z, Gao JL, Wan W, Ganesan S, McDermott DH, Murphy PM.

Eur J Immunol. 2015 Jun;45(6):1855-67. doi: 10.1002/eji.201445245. Epub 2015 Apr 24.

36.

Chromothriptic cure of WHIM syndrome.

McDermott DH, Gao JL, Liu Q, Siwicki M, Martens C, Jacobs P, Velez D, Yim E, Bryke CR, Hsu N, Dai Z, Marquesen MM, Stregevsky E, Kwatemaa N, Theobald N, Long Priel DA, Pittaluga S, Raffeld MA, Calvo KR, Maric I, Desmond R, Holmes KL, Kuhns DB, Balabanian K, Bachelerie F, Porcella SF, Malech HL, Murphy PM.

Cell. 2015 Feb 12;160(4):686-699. doi: 10.1016/j.cell.2015.01.014. Epub 2015 Feb 5.

37.

Regulation of motor function and behavior by atypical chemokine receptor 1.

Schneider EH, Fowler SC, Lionakis MS, Swamydas M, Holmes G, Diaz V, Munasinghe J, Peiper SC, Gao JL, Murphy PM.

Behav Genet. 2014 Sep;44(5):498-515. doi: 10.1007/s10519-014-9665-7. Epub 2014 Jul 6.

38.

New nomenclature for atypical chemokine receptors.

Bachelerie F, Graham GJ, Locati M, Mantovani A, Murphy PM, Nibbs R, Rot A, Sozzani S, Thelen M.

Nat Immunol. 2014 Mar;15(3):207-8. doi: 10.1038/ni.2812. No abstract available.

PMID:
24549061
39.

The Concise Guide to PHARMACOLOGY 2013/14: overview.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, Belelli D, Bennett AJ, Birdsall NJ, Boison D, Bonner TI, Brailsford L, Bröer S, Brown P, Calo G, Carter WG, Catterall WA, Chan SL, Chao MV, Chiang N, Christopoulos A, Chun JJ, Cidlowski J, Clapham DE, Cockcroft S, Connor MA, Cox HM, Cuthbert A, Dautzenberg FM, Davenport AP, Dawson PA, Dent G, Dijksterhuis JP, Dollery CT, Dolphin AC, Donowitz M, Dubocovich ML, Eiden L, Eidne K, Evans BA, Fabbro D, Fahlke C, Farndale R, Fitzgerald GA, Fong TM, Fowler CJ, Fry JR, Funk CD, Futerman AH, Ganapathy V, Gaisnier B, Gershengorn MA, Goldin A, Goldman ID, Gundlach AL, Hagenbuch B, Hales TG, Hammond JR, Hamon M, Hancox JC, Hauger RL, Hay DL, Hobbs AJ, Hollenberg MD, Holliday ND, Hoyer D, Hynes NA, Inui KI, Ishii S, Jacobson KA, Jarvis GE, Jarvis MF, Jensen R, Jones CE, Jones RL, Kaibuchi K, Kanai Y, Kennedy C, Kerr ID, Khan AA, Klienz MJ, Kukkonen JP, Lapoint JY, Leurs R, Lingueglia E, Lippiat J, Lolait SJ, Lummis SC, Lynch JW, MacEwan D, Maguire JJ, Marshall IL, May JM, McArdle CA, McGrath JC, Michel MC, Millar NS, Miller LJ, Mitolo V, Monk PN, Moore PK, Moorhouse AJ, Mouillac B, Murphy PM, Neubig RR, Neumaier J, Niesler B, Obaidat A, Offermanns S, Ohlstein E, Panaro MA, Parsons S, Pwrtwee RG, Petersen J, Pin JP, Poyner DR, Prigent S, Prossnitz ER, Pyne NJ, Pyne S, Quigley JG, Ramachandran R, Richelson EL, Roberts RE, Roskoski R, Ross RA, Roth M, Rudnick G, Ryan RM, Said SI, Schild L, Sanger GJ, Scholich K, Schousboe A, Schulte G, Schulz S, Serhan CN, Sexton PM, Sibley DR, Siegel JM, Singh G, Sitsapesan R, Smart TG, Smith DM, Soga T, Stahl A, Stewart G, Stoddart LA, Summers RJ, Thorens B, Thwaites DT, Toll L, Traynor JR, Usdin TB, Vandenberg RJ, Villalon C, Vore M, Waldman SA, Ward DT, Willars GB, Wonnacott SJ, Wright E, Ye RD, Yonezawa A, Zimmermann M.

Br J Pharmacol. 2013 Dec;170(8):1449-58. doi: 10.1111/bph.12444.

40.

A phase 1 clinical trial of long-term, low-dose treatment of WHIM syndrome with the CXCR4 antagonist plerixafor.

McDermott DH, Liu Q, Velez D, Lopez L, Anaya-O'Brien S, Ulrick J, Kwatemaa N, Starling J, Fleisher TA, Priel DA, Merideth MA, Giuntoli RL, Evbuomwan MO, Littel P, Marquesen MM, Hilligoss D, DeCastro R, Grimes GJ, Hwang ST, Pittaluga S, Calvo KR, Stratton P, Cowen EW, Kuhns DB, Malech HL, Murphy PM.

Blood. 2014 Apr 10;123(15):2308-16. doi: 10.1182/blood-2013-09-527226. Epub 2014 Feb 12.

41.

Glycaemic control in insulin requiring diabetes patients receiving exclusive enteral tube feeding in an acute hospital setting.

Murphy PM, Moore E, Flanagan DE.

Diabetes Res Clin Pract. 2014 Mar;103(3):426-9. doi: 10.1016/j.diabres.2013.12.007. Epub 2013 Dec 25.

PMID:
24462281
42.

International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors.

Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH, Locati M, Luster AD, Mantovani A, Matsushima K, Murphy PM, Nibbs R, Nomiyama H, Power CA, Proudfoot AE, Rosenkilde MM, Rot A, Sozzani S, Thelen M, Yoshie O, Zlotnik A.

Pharmacol Rev. 2013 Nov 11;66(1):1-79. doi: 10.1124/pr.113.007724. Print 2014. Review. Erratum in: Pharmacol Rev. 2014 Apr;66(2):467.

43.

CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.

Lionakis MS, Swamydas M, Fischer BG, Plantinga TS, Johnson MD, Jaeger M, Green NM, Masedunskas A, Weigert R, Mikelis C, Wan W, Lee CC, Lim JK, Rivollier A, Yang JC, Laird GM, Wheeler RT, Alexander BD, Perfect JR, Gao JL, Kullberg BJ, Netea MG, Murphy PM.

J Clin Invest. 2013 Dec;123(12):5035-51. doi: 10.1172/JCI71307. Epub 2013 Nov 1.

44.

A divergent variant of the eleventh human polyomavirus species, saint louis polyomavirus.

Pastrana DV, Fitzgerald PC, Phan GQ, Raiji MT, Murphy PM, McDermott DH, Velez D, Bliskovsky V, McBride AA, Buck CB.

Genome Announc. 2013 Oct 24;1(5). pii: e00812-13. doi: 10.1128/genomeA.00812-13.

45.

CCR5 deficiency and severe polio infection in the 1984 outbreak in Finland.

Rosenberg AS, Roivainen M, Hovi T, Liu Q, Murphy PM.

J Med Virol. 2013 Dec;85(12):2139-40. doi: 10.1002/jmv.23739. Epub 2013 Sep 13.

PMID:
24037958
46.

Intraluminal containment of commensal outgrowth in the gut during infection-induced dysbiosis.

Molloy MJ, Grainger JR, Bouladoux N, Hand TW, Koo LY, Naik S, Quinones M, Dzutsev AK, Gao JL, Trinchieri G, Murphy PM, Belkaid Y.

Cell Host Microbe. 2013 Sep 11;14(3):318-28. doi: 10.1016/j.chom.2013.08.003.

47.

Formylpeptide receptor-2 contributes to colonic epithelial homeostasis, inflammation, and tumorigenesis.

Chen K, Liu M, Liu Y, Yoshimura T, Shen W, Le Y, Durum S, Gong W, Wang C, Gao JL, Murphy PM, Wang JM.

J Clin Invest. 2013 Apr;123(4):1694-704.

48.

Regulation of atherogenesis by chemokines and chemokine receptors.

Wan W, Murphy PM.

Arch Immunol Ther Exp (Warsz). 2013 Feb;61(1):1-14. doi: 10.1007/s00005-012-0202-1. Epub 2012 Dec 7. Review.

49.

Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.

Wan W, Lionakis MS, Liu Q, Roffê E, Murphy PM.

Cardiovasc Res. 2013 Mar 1;97(3):580-8. doi: 10.1093/cvr/cvs349. Epub 2012 Nov 24.

50.

Formylpeptide receptors are critical for rapid neutrophil mobilization in host defense against Listeria monocytogenes.

Liu M, Chen K, Yoshimura T, Liu Y, Gong W, Wang A, Gao JL, Murphy PM, Wang JM.

Sci Rep. 2012;2:786. doi: 10.1038/srep00786. Epub 2012 Nov 8.

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