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Recent advances with Treg depleting fusion protein toxins for cancer immunotherapy.

Kumar P, Kumar A, Parveen S, Murphy JR, Bishai W.

Immunotherapy. 2019 Sep;11(13):1117-1128. doi: 10.2217/imt-2019-0060. Epub 2019 Jul 30.


Plasmodium vivax Infection in Multiple Family Members in Texas, USA.

Al Hammoud R, Murphy JR, Chang ML.

Case Rep Infect Dis. 2019 Jun 9;2019:8568710. doi: 10.1155/2019/8568710. eCollection 2019.


Corynebacterium diphtheriae: Diphtheria Toxin, the tox Operon, and Its Regulation by Fe2+ Activation of apo-DtxR.

Parveen S, Bishai WR, Murphy JR.

Microbiol Spectr. 2019 Jul;7(4). doi: 10.1128/microbiolspec.GPP3-0063-2019.


Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti-PD-1 in melanoma.

Cheung LS, Fu J, Kumar P, Kumar A, Urbanowski ME, Ihms EA, Parveen S, Bullen CK, Patrick GJ, Harrison R, Murphy JR, Pardoll DM, Bishai WR.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3100-3105. doi: 10.1073/pnas.1815087116. Epub 2019 Feb 4.


Maternal peripartum antibiotic exposure and the risk of postpartum depression.

Murphy JR, Paul S, Dunlop AL, Corwin EJ.

Res Nurs Health. 2018 Jul 19. doi: 10.1002/nur.21881. [Epub ahead of print]


Imported Congenital Rubella Syndrome, United States, 2017.

Al Hammoud R, Murphy JR, Pérez N.

Emerg Infect Dis. 2018 Apr;24(4):800-801. doi: 10.3201/eid2404.171540.


Molecular Detection and Identification of Rickettsia Species in Ticks (Acari: Ixodidae) Collected From Belize, Central America.

Polsomboon S, Hoel DF, Murphy JR, Linton YM, Motoki M, Robbins RG, Bautista K, Bricen O I, Achee NL, Grieco JP, Ching WM, Chao CC.

J Med Entomol. 2017 Nov 7;54(6):1718-1726. doi: 10.1093/jme/tjx141.


Suppressor Cell-Depleting Immunotherapy With Denileukin Diftitox is an Effective Host-Directed Therapy for Tuberculosis.

Gupta S, Cheung L, Pokkali S, Winglee K, Guo H, Murphy JR, Bishai WR.

J Infect Dis. 2017 Jun 15;215(12):1883-1887. doi: 10.1093/infdis/jix208.


Synthesis and Characterization of Ultrathin Silver Sulfide Nanoplatelets.

Kubie L, King LA, Kern ME, Murphy JR, Kattel S, Yang Q, Stecher JT, Rice WD, Parkinson BA.

ACS Nano. 2017 Aug 22;11(8):8471-8477. doi: 10.1021/acsnano.7b04280. Epub 2017 Aug 9.


Angiostrongylus cantonensis Meningitis and Myelitis, Texas, USA.

Al Hammoud R, Nayes SL, Murphy JR, Heresi GP, Butler IJ, Pérez N.

Emerg Infect Dis. 2017 Jun;23(6):1037-1038. doi: 10.3201/eid2306.161683.


Plasma Interferon-Gamma-Inducible Protein 10 Level Associates With Abnormal Memory B Cells Phenotypes in Perinatal HIV Infection.

Contreras GA, Murphy JR, Heresi GP.

Pediatr Infect Dis J. 2017 Sep;36(9):e219-e222. doi: 10.1097/INF.0000000000001612.


Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin.

Jones P, Storer RI, Sabnis YA, Wakenhut FM, Whitlock GA, England KS, Mukaiyama T, Dehnhardt CM, Coe JW, Kortum SW, Chrencik JE, Brown DG, Jones RM, Murphy JR, Yeoh T, Morgan P, Kilty I.

J Med Chem. 2017 Jan 26;60(2):767-786. doi: 10.1021/acs.jmedchem.6b01634. Epub 2017 Jan 4.


Regulatory B Cells Induce Formation of IL-10-Expressing T Cells in Mice with Autoimmune Neuroinflammation.

Pennati A, Ng S, Wu Y, Murphy JR, Deng J, Rangaraju S, Asress S, Blanchfield JL, Evavold B, Galipeau J.

J Neurosci. 2016 Dec 14;36(50):12598-12610. Epub 2016 Nov 7.


CD31 Expression on CD4+ Cells: A Simple Method for Quantitation of Recent Thymus Emigrant CD4 Cells.

Zakhour R, Tran DQ, Heresi GP, Degaffe G, Bell CS, Donnachie E, Zhang W, Pérez N, Benjamins LJ, Del Bianco G, Rodriguez G, Murphy JR.

Am J Trop Med Hyg. 2016 Oct 5;95(4):970-972. Epub 2016 Aug 15.


The Impact of a Concussion-U Educational Program on Knowledge of and Attitudes about Concussion.

Eagles ME, Bradbury-Squires DJ, Powell MF, Murphy JR, Campbell GD, Maroun FB.

Can J Neurol Sci. 2016 Sep;43(5):659-64. doi: 10.1017/cjn.2016.263. Epub 2016 Jul 28.


Effects of Preexposure to DEET on the Downstream Blood-Feeding Behaviors of Aedes aegypti (Diptera: Culicidae) Mosquitoes.

Sugiharto VA, Grieco JP, Murphy JR, Olsen CH, Colacicco-Mayhugh MG, Stewart VA, Achee NL, Turell MJ.

J Med Entomol. 2016 Sep 1;53(5):1100-1104. doi: 10.1093/jme/tjw066.


Functional Dissection of the Bipartite Active Site of the Class I Coenzyme A (CoA)-Transferase Succinyl-CoA:Acetate CoA-Transferase.

Murphy JR, Mullins EA, Kappock TJ.

Front Chem. 2016 May 23;4:23. doi: 10.3389/fchem.2016.00023. eCollection 2016.


Dengue Virus-1 Infection Did Not Alter the Behavioral Response of Aedes aegypti (Diptera: Culicidae) to DEET.

Sugiharto VA, Murphy JR, Turell MJ, Olsen CH, Stewart VA, Colacicco-Mayhugh MG, Grieco JP, Achee NL.

J Med Entomol. 2016 May;53(3):687-691. Epub 2016 Mar 29.


Recent Thymus Emigrant CD4+ T Cells Predict HIV Disease Progression in Patients With Perinatally Acquired HIV.

Zakhour R, Tran DQ, Degaffe G, Bell CS, Donnachie E, Zhang W, Pérez N, Benjamins LJ, Del Bianco G, Rodriguez G, Murphy JR, Heresi GP.

Clin Infect Dis. 2016 Apr 15;62(8):1029-1035. doi: 10.1093/cid/ciw030. Epub 2016 Feb 21.


Incidence and predictors of antiretroviral resistance in perinatally HIV-1 infected children and adolescents.

Contreras GA, Bell CS, Del Bianco G, Pérez N, Benjamins L, Kleinosky MT, Rodriguez G, Murphy JR, Heresi GP.

J Infect. 2016 Mar;72(3):353-61. doi: 10.1016/j.jinf.2015.12.005. Epub 2015 Dec 19.


The Infant Microbiome: Implications for Infant Health and Neurocognitive Development.

Yang I, Corwin EJ, Brennan PA, Jordan S, Murphy JR, Dunlop A.

Nurs Res. 2016 Jan-Feb;65(1):76-88. doi: 10.1097/NNR.0000000000000133. Review.


Mn(2+)-Doped CdSe/CdS Core/Multishell Colloidal Quantum Wells Enabling Tunable Carrier-Dopant Exchange Interactions.

Delikanli S, Akgul MZ, Murphy JR, Barman B, Tsai Y, Scrace T, Zhang P, Bozok B, Hernández-Martínez PL, Christodoulides J, Cartwright AN, Petrou A, Demir HV.

ACS Nano. 2015 Dec 22;9(12):12473-9. doi: 10.1021/acsnano.5b05903. Epub 2015 Nov 26.


An active site-tail interaction in the structure of hexahistidine-tagged Thermoplasma acidophilum citrate synthase.

Murphy JR, Donini S, Kappock TJ.

Acta Crystallogr F Struct Biol Commun. 2015 Oct;71(Pt 10):1292-9. doi: 10.1107/S2053230X15015939. Epub 2015 Sep 23.


Detection of Dengue Virus in Mosquito Extracts and Human Clinical Samples Using a Field Expedient Molecular Platform.

Pal S, Richardson JH, Murphy JR, Krairojananan P, Kongtak P, Jaichapor B, Kankaew P, Ekanayake S, Davis TJ, Maserang DL, Teng DH, Crisp RJ, Wu SJ, Coleman RE, McAvin JC, Swaby JA.

Mil Med. 2015 Sep;180(9):937-42. doi: 10.7205/MILMED-D-14-00428.


Forkhead box protein 3(+) regulatory T cells and Helios(+) subset in perinatally acquired HIV.

Degaffe G, Zakhour R, Zhang W, Contreras GA, Bell CS, Rodriguez G, Del Bianco G, Pérez N, Benjamins LJ, Murphy JR, Heresi GP, Tran DQ.

Clin Exp Immunol. 2015 Apr;180(1):108-17. doi: 10.1111/cei.12560.


Neuromuscular fatigue of the knee extensors during repeated maximal intensity intermittent-sprints on a cycle ergometer.

Pearcey GE, Murphy JR, Behm DG, Hay DC, Power KE, Button DC.

Muscle Nerve. 2015 Apr;51(4):569-79. doi: 10.1002/mus.24342. Epub 2015 Feb 11.


Using infective mosquitoes to challenge monkeys with Plasmodium knowlesi in malaria vaccine studies.

Murphy JR, Weiss WR, Fryauff D, Dowler M, Savransky T, Stoyanov C, Muratova O, Lambert L, Orr-Gonzalez S, Zeleski KL, Hinderer J, Fay MP, Joshi G, Gwadz RW, Richie TL, Villasante EF, Richardson JH, Duffy PE, Chen J.

Malar J. 2014 Jun 3;13:215. doi: 10.1186/1475-2875-13-215.


Persistently high perinatal transmission of HIV: assessment of risk factors.

Del Bianco G, Bell CS, Benjamins LJ, Pérez N, Rodriguez G, Murphy JR, Heresi GP.

Pediatr Infect Dis J. 2014 Jun;33(6):e151-7. doi: 10.1097/INF.0000000000000199.


Cardiovascular disease is associated with COPD severity and reduced functional status and quality of life.

Black-Shinn JL, Kinney GL, Wise AL, Regan EA, Make B, Krantz MJ, Barr RG, Murphy JR, Lynch D, Silverman EK, Crapo JD, Hokanson JE; COPDGene Investigators.

COPD. 2014 Sep;11(5):546-51. doi: 10.3109/15412555.2014.898029. Epub 2014 May 15.


Prepubescent males are less susceptible to neuromuscular fatigue following resistance exercise.

Murphy JR, Button DC, Chaouachi A, Behm DG.

Eur J Appl Physiol. 2014 Apr;114(4):825-35. doi: 10.1007/s00421-013-2809-2. Epub 2014 Jan 8.


Detection of NH1N1 influenza virus in nonrespiratory sites among children.

Wootton SH, Aguilera EA, Wanger A, Jewell A, Patel K, Murphy JR, Piedra PA.

Pediatr Infect Dis J. 2014 Jan;33(1):95-6. doi: 10.1097/INF.0b013e3182a09de7.


Commercial DNA extraction kits impact observed microbial community composition in permafrost samples.

Vishnivetskaya TA, Layton AC, Lau MC, Chauhan A, Cheng KR, Meyers AJ, Murphy JR, Rogers AW, Saarunya GS, Williams DE, Pfiffner SM, Biggerstaff JP, Stackhouse BT, Phelps TJ, Whyte L, Sayler GS, Onstott TC.

FEMS Microbiol Ecol. 2014 Jan;87(1):217-30. doi: 10.1111/1574-6941.12219. Epub 2013 Oct 17.


Accidental introductions are an important source of invasive plants in the continental United States.

Lehan NE, Murphy JR, Thorburn LP, Bradley BA.

Am J Bot. 2013 Jul;100(7):1287-93. doi: 10.3732/ajb.1300061. Epub 2013 Jul 3.


Prevalence and risk factors associated with resistance-associated mutations to etravirine in a cohort of perinatally HIV-infected children.

Contreras GA, Bell CS, Del Bianco GP, Pérez N, Kleinosky MT, Murphy JR, Heresi GP.

J Antimicrob Chemother. 2013 Oct;68(10):2344-8. doi: 10.1093/jac/dkt198. Epub 2013 Jun 3.


Severe narrowing of left cavernous carotid artery associated with Fusobacterium necrophorum infection.

DeGaffe GH, Murphy JR, Butler IJ, Shelburne J, Heresi GP.

Anaerobe. 2013 Aug;22:118-20. doi: 10.1016/j.anaerobe.2013.04.001. Epub 2013 May 7.


Therapeutic targeting of regulatory T cells enhances tumor-specific CD8+ T cell responses in Epstein-Barr virus associated nasopharyngeal carcinoma.

Fogg M, Murphy JR, Lorch J, Posner M, Wang F.

Virology. 2013 Jul 5;441(2):107-13. doi: 10.1016/j.virol.2013.03.016. Epub 2013 Apr 17.


Transgenic parasites stably expressing full-length Plasmodium falciparum circumsporozoite protein as a model for vaccine down-selection in mice using sterile protection as an endpoint.

Porter MD, Nicki J, Pool CD, DeBot M, Illam RM, Brando C, Bozick B, De La Vega P, Angra D, Spaccapelo R, Crisanti A, Murphy JR, Bennett JW, Schwenk RJ, Ockenhouse CF, Dutta S.

Clin Vaccine Immunol. 2013 Jun;20(6):803-10. doi: 10.1128/CVI.00066-13. Epub 2013 Mar 27.


Reduced duration mismatch negativity in adolescents with psychotic symptoms: further evidence for mismatch negativity as a possible biomarker for vulnerability to psychosis.

Murphy JR, Rawdon C, Kelleher I, Twomey D, Markey PS, Cannon M, Roche RA.

BMC Psychiatry. 2013 Feb 2;13:45. doi: 10.1186/1471-244X-13-45.


Mechanism for calcium ion sensing by the C2A domain of synaptotagmin I.

Gauer JW, Sisk R, Murphy JR, Jacobson H, Sutton RB, Gillispie GD, Hinderliter A.

Biophys J. 2012 Jul 18;103(2):238-46. doi: 10.1016/j.bpj.2012.05.051. Epub 2012 Jul 17.


Quantitative computed tomography of the lungs and airways in healthy nonsmoking adults.

Zach JA, Newell JD Jr, Schroeder J, Murphy JR, Curran-Everett D, Hoffman EA, Westgate PM, Han MK, Silverman EK, Crapo JD, Lynch DA; COPDGene Investigators.

Invest Radiol. 2012 Oct;47(10):596-602.


Mosquito bisection as a variable in estimates of PCR-derived malaria sporozoite rates.

Foley DH, Harrison G, Murphy JR, Dowler M, Rueda LM, Wilkerson RC.

Malar J. 2012 May 2;11:145. doi: 10.1186/1475-2875-11-145.


Prepregnancy obesity and complement system activation in early pregnancy and the subsequent development of preeclampsia.

Lynch AM, Eckel RH, Murphy JR, Gibbs RS, West NA, Giclas PC, Salmon JE, Holers VM.

Am J Obstet Gynecol. 2012 May;206(5):428.e1-8. doi: 10.1016/j.ajog.2012.02.035. Epub 2012 Mar 7.


A combined pulmonary-radiology workshop for visual evaluation of COPD: study design, chest CT findings and concordance with quantitative evaluation.

COPDGene CT Workshop Group, Barr RG, Berkowitz EA, Bigazzi F, Bode F, Bon J, Bowler RP, Chiles C, Crapo JD, Criner GJ, Curtis JL, Dass C, Dirksen A, Dransfield MT, Edula G, Erikkson L, Friedlander A, Galperin-Aizenberg M, Gefter WB, Gierada DS, Grenier PA, Goldin J, Han MK, Hanania NA, Hansel NN, Jacobson FL, Kauczor HU, Kinnula VL, Lipson DA, Lynch DA, MacNee W, Make BJ, Mamary AJ, Mann H, Marchetti N, Mascalchi M, McLennan G, Murphy JR, Naidich D, Nath H, Newell JD Jr, Pistolesi M, Regan EA, Reilly JJ, Sandhaus R, Schroeder JD, Sciurba F, Shaker S, Sharafkhaneh A, Silverman EK, Steiner RM, Strange C, Sverzellati N, Tashjian JH, van Beek EJ, Washington L, Washko GR, Westney G, Wood SA, Woodruff PG.

COPD. 2012 Apr;9(2):151-9. doi: 10.3109/15412555.2012.654923. Epub 2012 Mar 19.


Demographic, physiologic and radiographic characteristics of COPD patients taking chronic systemic corticosteroids.

Swift I, Satti A, Kim V, Make BJ, Newell J, Steiner RM, Wilson C, Murphy JR, Silverman EK, Criner GJ; COPDGene® Investigators.

COPD. 2012 Feb;9(1):29-35. doi: 10.3109/15412555.2011.634454.


Single genotypes underestimate the prevalence of antiretroviral resistance in patients with perinatally acquired HIV.

Contreras GA, Delbianco G, Bell CS, Kleinosky MT, Murphy JR, Heresi GP.

J Infect. 2012 Jan;64(1):125-6. doi: 10.1016/j.jinf.2011.10.013. Epub 2011 Nov 4. No abstract available.


Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity.

Epstein JE, Tewari K, Lyke KE, Sim BK, Billingsley PF, Laurens MB, Gunasekera A, Chakravarty S, James ER, Sedegah M, Richman A, Velmurugan S, Reyes S, Li M, Tucker K, Ahumada A, Ruben AJ, Li T, Stafford R, Eappen AG, Tamminga C, Bennett JW, Ockenhouse CF, Murphy JR, Komisar J, Thomas N, Loyevsky M, Birkett A, Plowe CV, Loucq C, Edelman R, Richie TL, Seder RA, Hoffman SL.

Science. 2011 Oct 28;334(6055):475-80. doi: 10.1126/science.1211548. Epub 2011 Sep 8.


A Dimensional Bus model for integrating clinical and research data.

Wade TD, Hum RC, Murphy JR.

J Am Med Inform Assoc. 2011 Dec;18 Suppl 1:i96-102. doi: 10.1136/amiajnl-2011-000339. Epub 2011 Aug 19.


Refractory asthma: importance of bronchoscopy to identify phenotypes and direct therapy.

Good JT Jr, Kolakowski CA, Groshong SD, Murphy JR, Martin RJ.

Chest. 2012 Mar;141(3):599-606. doi: 10.1378/chest.11-0741. Epub 2011 Aug 11.


GRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro.

Tamayo AG, Slater L, Taylor-Parker J, Bharti A, Harrison R, Hung DT, Murphy JR.

Mol Microbiol. 2011 Sep;81(5):1390-401. doi: 10.1111/j.1365-2958.2011.07770.x. Epub 2011 Jul 29.

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