Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 644


The Killer Pseudokinase Mixed Lineage Kinase Domain-Like Protein (MLKL).

Murphy JM.

Cold Spring Harb Perspect Biol. 2019 Nov 11. pii: a036376. doi: 10.1101/cshperspect.a036376. [Epub ahead of print]


The PEAK family of pseudokinases, their role in cell signalling and cancer.

Patel O, Roy MJ, Murphy JM, Lucet IS.

FEBS J. 2019 Oct 9. doi: 10.1111/febs.15087. [Epub ahead of print] Review.


Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3.

Petrie EJ, Sandow JJ, Lehmann WIL, Liang LY, Coursier D, Young SN, Kersten WJA, Fitzgibbon C, Samson AL, Jacobsen AV, Lowes KN, Au AE, Jousset Sabroux H, Lalaoui N, Webb AI, Lessene G, Manning G, Lucet IS, Murphy JM.

Cell Rep. 2019 Sep 24;28(13):3309-3319.e5. doi: 10.1016/j.celrep.2019.08.055.


The long-awaited structure of HIPK2.

Murphy JM.

J Biol Chem. 2019 Sep 13;294(37):13560-13561. doi: 10.1074/jbc.H119.010675.


Emerging concepts in pseudoenzyme classification, evolution, and signaling.

Ribeiro AJM, Das S, Dawson N, Zaru R, Orchard S, Thornton JM, Orengo C, Zeqiraj E, Murphy JM, Eyers PA.

Sci Signal. 2019 Aug 13;12(594). pii: eaat9797. doi: 10.1126/scisignal.aat9797. Review.


Eph receptor signalling: from catalytic to non-catalytic functions.

Liang LY, Patel O, Janes PW, Murphy JM, Lucet IS.

Oncogene. 2019 Sep;38(39):6567-6584. doi: 10.1038/s41388-019-0931-2. Epub 2019 Aug 12. Review.


A Quantitative Method to Measure Low Levels of ROS in Nonphagocytic Cells by Using a Chemiluminescent Imaging System.

Kim JS, Jeong K, Murphy JM, Rodriguez YAR, Lim SS.

Oxid Med Cell Longev. 2019 Jun 11;2019:1754593. doi: 10.1155/2019/1754593. eCollection 2019.


A Randomized Feasibility Trial of a Novel, Integrative, and Intensive Virtual Rehabilitation Program for Service Members Post-Acquired Brain Injury.

Buccellato KH, Nordstrom M, Murphy JM, Burdea GC, Polistico K, House G, Kim N, Grampurohit N, Sorensen J, Isaacson BM, Pasquina PF.

Mil Med. 2019 Jul 3. pii: usz150. doi: 10.1093/milmed/usz150. [Epub ahead of print]


Changes in local free-living parasite populations in response to cleaner manipulation over 12 years.

Grutter AS, Blomberg SP, Box S, Bshary R, Ho O, Madin EMP, McClure EC, Meekan MG, Murphy JM, Richardson MA, Sikkel PC, Sims CA, Sun D, Warner RR.

Oecologia. 2019 Aug;190(4):783-797. doi: 10.1007/s00442-019-04451-8. Epub 2019 Jul 2.


The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1β Release.

Rashidi M, Simpson DS, Hempel A, Frank D, Petrie E, Vince A, Feltham R, Murphy J, Chatfield SM, Salvesen GS, Murphy JM, Wicks IP, Vince JE.

J Immunol. 2019 Aug 1;203(3):736-748. doi: 10.4049/jimmunol.1900228. Epub 2019 Jun 17.


Utilization of Child Psychiatry Consultation Embedded in Primary Care for an Urban, Latino Population.

Spencer AE, Chiang C, Plasencia N, Biederman J, Sun Y, Gebara C; MGH Chelsea HealthCare Center, Jellinek M, Murphy JM, Zima BT.

J Health Care Poor Underserved. 2019;30(2):637-652. doi: 10.1353/hpu.2019.0047.


FAK and Pyk2 activity promote TNF-α and IL-1β-mediated pro-inflammatory gene expression and vascular inflammation.

Murphy JM, Jeong K, Rodriguez YAR, Kim JH, Ahn EE, Lim SS.

Sci Rep. 2019 May 20;9(1):7617. doi: 10.1038/s41598-019-44098-2.


Usefulness of a Novel System for Feedback of Patient-Reported Outcome Measures in Children Recovering From Burns.

Riobueno-Naylor A, Romo S, Kazis L, Wang S, Lydon M, Nelson J, Fowler L, Drexler A, Kogosov A, Haile H, Ryan CM, Chang P, Warner P, Palmieri TL, Lee AF, Stoddard F, Murphy JM, Sheridan RL.

J Burn Care Res. 2019 Oct 16;40(6):776-784. doi: 10.1093/jbcr/irz082.


Nuclear Focal Adhesion Kinase Controls Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia Through GATA4-Mediated Cyclin D1 Transcription.

Jeong K, Kim JH, Murphy JM, Park H, Kim SJ, Rodriguez YAR, Kong H, Choi C, Guan JL, Taylor JM, Lincoln TM, Gerthoffer WT, Kim JS, Ahn EE, Schlaepfer DD, Lim SS.

Circ Res. 2019 Jul 5;125(2):152-166. doi: 10.1161/CIRCRESAHA.118.314344. Epub 2019 May 17.


Regulated necrosis in kidney ischemia-reperfusion injury.

Pefanis A, Ierino FL, Murphy JM, Cowan PJ.

Kidney Int. 2019 Aug;96(2):291-301. doi: 10.1016/j.kint.2019.02.009. Epub 2019 Mar 7. Review.


Stability constant determination of sulfur and selenium amino acids with Cu(II) and Fe(II).

Murphy JM, Gaertner AAE, Williams T, McMillen CD, Powell BA, Brumaghim JL.

J Inorg Biochem. 2019 Jun;195:20-30. doi: 10.1016/j.jinorgbio.2019.03.001. Epub 2019 Mar 4.


A Dual-Modality Linker Enables Site-Specific Conjugation of Antibody Fragments for 18F-Immuno-PET and Fluorescence Imaging.

Zettlitz KA, Waldmann CM, Tsai WK, Tavaré R, Collins J, Murphy JM, Wu AM.

J Nucl Med. 2019 Oct;60(10):1467-1473. doi: 10.2967/jnumed.118.223560. Epub 2019 Mar 15.


Survival/Adaptation of Bone Marrow-Derived Mesenchymal Stem Cells After Long-Term Starvation Through Selective Processes.

Ferro F, Spelat R, Shaw G, Duffy N, Islam MN, O'Shea PM, O'Toole D, Howard L, Murphy JM.

Stem Cells. 2019 Jun;37(6):813-827. doi: 10.1002/stem.2998. Epub 2019 Mar 25.


Mesenchymal Stem Cell Therapy for Osteoarthritis: The Critical Role of the Cell Secretome.

Mancuso P, Raman S, Glynn A, Barry F, Murphy JM.

Front Bioeng Biotechnol. 2019 Jan 29;7:9. doi: 10.3389/fbioe.2019.00009. eCollection 2019. Review.


Lifetime experience of multiple common mental disorders and 19-year mortality: results from a Canadian population-based cohort.

Kingsbury M, Sucha E, Horton NJ, Sampasa-Kanyinga H, Murphy JM, Gilman SE, Colman I.

Epidemiol Psychiatr Sci. 2019 Feb 4:1-7. doi: 10.1017/S2045796018000859. [Epub ahead of print]


Activated MLKL attenuates autophagy following its translocation to intracellular membranes.

Frank D, Vaux DL, Murphy JM, Vince JE, Lindqvist LM.

J Cell Sci. 2019 Feb 28;132(5). pii: jcs220996. doi: 10.1242/jcs.220996.


SMCHD1 is involved in de novo methylation of the DUX4-encoding D4Z4 macrosatellite.

Dion C, Roche S, Laberthonnière C, Broucqsault N, Mariot V, Xue S, Gurzau AD, Nowak A, Gordon CT, Gaillard MC, El-Yazidi C, Thomas M, Schlupp-Robaglia A, Missirian C, Malan V, Ratbi L, Sefiani A, Wollnik B, Binetruy B, Salort Campana E, Attarian S, Bernard R, Nguyen K, Amiel J, Dumonceaux J, Murphy JM, Déjardin J, Blewitt ME, Reversade B, Robin JD, Magdinier F.

Nucleic Acids Res. 2019 Apr 8;47(6):2822-2839. doi: 10.1093/nar/gkz005.


FAK inhibition reduces metastasis of α4 integrin-expressing melanoma to lymph nodes by targeting lymphatic VCAM-1 expression.

Jeong K, Murphy JM, Rodriguez YAR, Kim JS, Ahn EE, Lim SS.

Biochem Biophys Res Commun. 2019 Feb 19;509(4):1034-1040. doi: 10.1016/j.bbrc.2019.01.050. Epub 2019 Jan 17.


Advance Care Planning in the Nursing Home Setting: A Practice Improvement Evaluation.

Kezirian AC, McGregor MJ, Stead U, Sakaluk T, Spring B, Turgeon S, Slater J, Murphy JM.

J Soc Work End Life Palliat Care. 2018 Oct-Dec;14(4):328-345. doi: 10.1080/15524256.2018.1547673. Epub 2019 Jan 17.


Transitional Mentor Education Program Pilot: Preparing Nurses to Adapt to Changing Acute Care Settings.

Shermont H, Pignataro S, Moonan M, Memmolo S, Murphy JM.

J Nurses Prof Dev. 2019 Jan/Feb;35(1):32-38. doi: 10.1097/NND.0000000000000508.


The Structural Basis of Necroptotic Cell Death Signaling.

Petrie EJ, Czabotar PE, Murphy JM.

Trends Biochem Sci. 2019 Jan;44(1):53-63. doi: 10.1016/j.tibs.2018.11.002. Epub 2018 Nov 30. Review.


The anticonvulsive Phenhydan® suppresses extrinsic cell death.

Moerke C, Jaco I, Dewitz C, Müller T, Jacobsen AV, Gautheron J, Fritsch J, Schmitz J, Bräsen JH, Günther C, Murphy JM, Kunzendorf U, Meier P, Krautwald S.

Cell Death Differ. 2019 Sep;26(9):1631-1645. doi: 10.1038/s41418-018-0232-2. Epub 2018 Nov 15.


Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway.

Jansz N, Nesterova T, Keniry A, Iminitoff M, Hickey PF, Pintacuda G, Masui O, Kobelke S, Geoghegan N, Breslin KA, Willson TA, Rogers K, Kay GF, Fox AH, Koseki H, Brockdorff N, Murphy JM, Blewitt ME.

Cell Rep. 2018 Nov 13;25(7):1912-1923.e9. doi: 10.1016/j.celrep.2018.10.044.


The Use of a Brief Measure to Assess Longitudinal Changes in Appearance Concerns for Youth Recovering From Burn Injuries.

Weed VF, Canenguez K, Romo S, Wang SL, Kazis L, Lee AF, Herndon D, Palmieri TL, Warner P, Haile H, Sheridan RL, Murphy JM.

J Burn Care Res. 2019 Jan 1;40(1):97-103. doi: 10.1093/jbcr/iry054.


Genetic variation and population structure among larval Lethenteron spp. within the Yukon River drainage, Alaska.

Shink KG, Sutton TM, Murphy JM, López JA.

J Fish Biol. 2018 Dec;93(6):1130-1140. doi: 10.1111/jfb.13833. Epub 2018 Nov 21.


ADAP is an upstream regulator that precedes SLP-76 at sites of TCR engagement and stabilizes signaling microclusters.

Lewis JB, Scangarello FA, Murphy JM, Eidell KP, Sodipo MO, Ophir MJ, Sargeant R, Seminario MC, Bunnell SC.

J Cell Sci. 2018 Nov 8;131(21). pii: jcs215517. doi: 10.1242/jcs.215517.


Neurological soft signs and cognitive performance in early childhood.

Alamiri B, Nelson C, Fitzmaurice GM, Murphy JM, Gilman SE.

Dev Psychol. 2018 Nov;54(11):2043-2052. doi: 10.1037/dev0000566. Epub 2018 Sep 27.


A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes.

Foglizzo M, Middleton AJ, Burgess AE, Crowther JM, Dobson RCJ, Murphy JM, Day CL, Mace PD.

Nat Commun. 2018 Sep 26;9(1):3932. doi: 10.1038/s41467-018-06186-1.


Automated concentration of [18F]fluoride into microliter volumes.

Chao PH, Lazari M, Hanet S, Narayanam MK, Murphy JM, van Dam RM.

Appl Radiat Isot. 2018 Nov;141:138-148. doi: 10.1016/j.apradiso.2018.06.017. Epub 2018 Jun 23.


Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters.

Jansz N, Keniry A, Trussart M, Bildsoe H, Beck T, Tonks ID, Mould AW, Hickey P, Breslin K, Iminitoff M, Ritchie ME, McGlinn E, Kay GF, Murphy JM, Blewitt ME.

Nat Struct Mol Biol. 2018 Sep;25(9):766-777. doi: 10.1038/s41594-018-0111-z. Epub 2018 Aug 20.


Screening for Attention-Deficit/Hyperactivity Disorder and Comorbidities in a Diverse, Urban Primary Care Setting.

Spencer AE, Plasencia N, Sun Y, Lucke C, Haile H, Cronin R, Faraone SV, Jellinek M, Murphy JM, Biederman J.

Clin Pediatr (Phila). 2018 Oct;57(12):1442-1452. doi: 10.1177/0009922818787329. Epub 2018 Jul 13.


Cryo-EM structure of an essential Plasmodium vivax invasion complex.

Gruszczyk J, Huang RK, Chan LJ, Menant S, Hong C, Murphy JM, Mok YF, Griffin MDW, Pearson RD, Wong W, Cowman AF, Yu Z, Tham WH.

Nature. 2018 Jul;559(7712):135-139. doi: 10.1038/s41586-018-0249-1. Epub 2018 Jun 27.


Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis.

Petrie EJ, Sandow JJ, Jacobsen AV, Smith BJ, Griffin MDW, Lucet IS, Dai W, Young SN, Tanzer MC, Wardak A, Liang LY, Cowan AD, Hildebrand JM, Kersten WJA, Lessene G, Silke J, Czabotar PE, Webb AI, Murphy JM.

Nat Commun. 2018 Jun 21;9(1):2422. doi: 10.1038/s41467-018-04714-7.


Reducing Readmissions Post-tonsillectomy: A Quality Improvement Study on Intravenous Hydration.

Hession-Laband E, Melvin P, Shermont H, Murphy JM, Bukoye B, Amin M.

J Healthc Qual. 2018 Jul/Aug;40(4):217-227. doi: 10.1097/JHQ.0000000000000143.


Hospital-Based Quality Measures for Pediatric Mental Health Care.

Bardach NS, Burkhart Q, Richardson LP, Roth CP, Murphy JM, Parast L, Gidengil CA, Marmet J, Britto MT, Mangione-Smith R.

Pediatrics. 2018 Jun;141(6). pii: e20173554. doi: 10.1542/peds.2017-3554.


FSHD2- and BAMS-associated mutations confer opposing effects on SMCHD1 function.

Gurzau AD, Chen K, Xue S, Dai W, Lucet IS, Ly TTN, Reversade B, Blewitt ME, Murphy JM.

J Biol Chem. 2018 Jun 22;293(25):9841-9853. doi: 10.1074/jbc.RA118.003104. Epub 2018 May 10.


Depressive and anxious symptoms and 20-year mortality: Evidence from the Stirling County study.

Colman I, Kingsbury M, Sucha E, Horton NJ, Murphy JM, Gilman SE.

Depress Anxiety. 2018 Jul;35(7):638-647. doi: 10.1002/da.22750. Epub 2018 May 2.


Advancing national climate change risk assessment to deliver national adaptation plans.

Warren RF, Wilby RL, Brown K, Watkiss P, Betts RA, Murphy JM, Lowe JA.

Philos Trans A Math Phys Eng Sci. 2018 Jun 13;376(2121). pii: 20170295. doi: 10.1098/rsta.2017.0295.


Readily Accessible Ambiphilic Cyclopentadienes for Bioorthogonal Labeling.

Levandowski BJ, Gamache RF, Murphy JM, Houk KN.

J Am Chem Soc. 2018 May 23;140(20):6426-6431. doi: 10.1021/jacs.8b02978. Epub 2018 May 15.


Origins of halogen effects in bioorthogonal sydnone cycloadditions.

Tao H, Liu F, Zeng R, Shao Z, Zou L, Cao Y, Murphy JM, Houk KN, Liang Y.

Chem Commun (Camb). 2018 May 15;54(40):5082-5085. doi: 10.1039/c8cc02128g.


The molecular basis of JAK/STAT inhibition by SOCS1.

Liau NPD, Laktyushin A, Lucet IS, Murphy JM, Yao S, Whitlock E, Callaghan K, Nicola NA, Kershaw NJ, Babon JJ.

Nat Commun. 2018 Apr 19;9(1):1558. doi: 10.1038/s41467-018-04013-1.


Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis.

Raman S, FitzGerald U, Murphy JM.

Front Bioeng Biotechnol. 2018 Mar 14;6:22. doi: 10.3389/fbioe.2018.00022. eCollection 2018. Review.


An evidence-based oral health promotion programme: Lessons from Leicester.

Murphy JM, Burch TE, Dickenson AJ, Wong J, Moore R.

Oral Dis. 2018 Mar;24(1-2):38-43. doi: 10.1111/odi.12743.


Vascular Calcification: Is it rather a Stem/Progenitor Cells Driven Phenomenon?

Leszczynska A, Murphy JM.

Front Bioeng Biotechnol. 2018 Feb 9;6:10. doi: 10.3389/fbioe.2018.00010. eCollection 2018. Review.


The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis.

Davies KA, Tanzer MC, Griffin MDW, Mok YF, Young SN, Qin R, Petrie EJ, Czabotar PE, Silke J, Murphy JM.

Cell Death Differ. 2018 Sep;25(9):1567-1580. doi: 10.1038/s41418-018-0061-3. Epub 2018 Feb 14.

Supplemental Content

Loading ...
Support Center