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Items: 1 to 50 of 371

1.

Differential Distribution of the Epigenetic Marker 5-hydroxymethylcytosine Occurs in Hair Follicle Stem Cells during Bulge Activation.

Leavitt D, Wells M, Abarzua P, Murphy GF, Lian CG.

J Cutan Pathol. 2019 Feb 4. doi: 10.1111/cup.13434. [Epub ahead of print]

PMID:
30719726
2.

Nrf2 regulates CD4+ T cell-induced acute graft-versus-host disease in mice.

Tsai JJ, Velardi E, Shono Y, Argyropoulos KV, Holland AM, Smith OM, Yim NL, Rao UK, Kreines FM, Lieberman SR, Young LF, Lazrak A, Youssef S, Fu YY, Liu C, Lezcano C, Murphy GF, Na IK, Jenq RR, Hanash AM, Dudakov JA, van den Brink MRM.

Blood. 2018 Dec 27;132(26):2763-2774. doi: 10.1182/blood-2017-10-812941. Epub 2018 Oct 31.

PMID:
30381375
3.

Targeting antigen-presenting cells by anti-PD-1 nanoparticles augments antitumor immunity.

Ordikhani F, Uehara M, Kasinath V, Dai L, Eskandari SK, Bahmani B, Yonar M, Azzi JR, Haik Y, Sage PT, Murphy GF, Annabi N, Schatton T, Guleria I, Abdi R.

JCI Insight. 2018 Oct 18;3(20). pii: 122700. doi: 10.1172/jci.insight.122700. [Epub ahead of print]

4.

Chronic rejection of human face allografts.

Krezdorn N, Lian CG, Wells M, Wo L, Tasigiorgos S, Xu S, Borges TJ, Frierson RM, Stanek E, Riella LV, Pomahac B, Murphy GF.

Am J Transplant. 2018 Oct 12. doi: 10.1111/ajt.15143. [Epub ahead of print]

PMID:
30312535
5.

Increased levels of circulating MMP3 correlate with severe rejection in face transplantation.

Kollar B, Shubin A, Borges TJ, Tasigiorgos S, Win TS, Lian CG, Dillon ST, Gu X, Wyrobnik I, Murphy GF, Pomahac B, Libermann TA, Riella LV.

Sci Rep. 2018 Oct 8;8(1):14915. doi: 10.1038/s41598-018-33272-7.

6.

Loss of GCNT2/I-branched glycans enhances melanoma growth and survival.

Sweeney JG, Liang J, Antonopoulos A, Giovannone N, Kang S, Mondala TS, Head SR, King SL, Tani Y, Brackett D, Dell A, Murphy GF, Haslam SM, Widlund HR, Dimitroff CJ.

Nat Commun. 2018 Aug 22;9(1):3368. doi: 10.1038/s41467-018-05795-0.

7.

Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer.

Wu D, Hu D, Chen H, Shi G, Fetahu IS, Wu F, Rabidou K, Fang R, Tan L, Xu S, Liu H, Argueta C, Zhang L, Mao F, Yan G, Chen J, Dong Z, Lv R, Xu Y, Wang M, Ye Y, Zhang S, Duquette D, Geng S, Yin C, Lian CG, Murphy GF, Adler GK, Garg R, Lynch L, Yang P, Li Y, Lan F, Fan J, Shi Y, Shi YG.

Nature. 2018 Jul;559(7715):637-641. doi: 10.1038/s41586-018-0350-5. Epub 2018 Jul 18.

PMID:
30022161
8.

Association of Nodal Metastasis and Mortality With Vermilion vs Cutaneous Lip Location in Cutaneous Squamous Cell Carcinoma of the Lip.

Wang DM, Kraft S, Rohani P, Murphy GF, Besaw RJ, Karia PS, Morgan FC, Schmults CD.

JAMA Dermatol. 2018 Jun 1;154(6):701-707. doi: 10.1001/jamadermatol.2018.0792.

PMID:
29801066
9.

ATP-binding cassette member B5 (ABCB5) promotes tumor cell invasiveness in human colorectal cancer.

Guo Q, Grimmig T, Gonzalez G, Giobbie-Hurder A, Berg G, Carr N, Wilson BJ, Banerjee P, Ma J, Gold JS, Nandi B, Huang Q, Waaga-Gasser AM, Lian CG, Murphy GF, Frank MH, Gasser M, Frank NY.

J Biol Chem. 2018 Jul 13;293(28):11166-11178. doi: 10.1074/jbc.RA118.003187. Epub 2018 May 22.

PMID:
29789423
10.

Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.

Shukla SA, Bachireddy P, Schilling B, Galonska C, Zhan Q, Bango C, Langer R, Lee PC, Gusenleitner D, Keskin DB, Babadi M, Mohammad A, Gnirke A, Clement K, Cartun ZJ, Van Allen EM, Miao D, Huang Y, Snyder A, Merghoub T, Wolchok JD, Garraway LA, Meissner A, Weber JS, Hacohen N, Neuberg D, Potts PR, Murphy GF, Lian CG, Schadendorf D, Hodi FS, Wu CJ.

Cell. 2018 Apr 19;173(3):624-633.e8. doi: 10.1016/j.cell.2018.03.026. Epub 2018 Apr 12.

PMID:
29656892
11.

Epigenetic Reprogramming Strategies to Reverse Global Loss of 5-Hydroxymethylcytosine, a Prognostic Factor for Poor Survival in High-grade Serous Ovarian Cancer.

Tucker DW, Getchell CR, McCarthy ET, Ohman AW, Sasamoto N, Xu S, Ko JY, Gupta M, Shafrir A, Medina JE, Lee JJ, MacDonald LA, Malik A, Hasselblatt KT, Li W, Zhang H, Kaplan SJ, Murphy GF, Hirsch MS, Liu JF, Matulonis UA, Terry KL, Lian CG, Dinulescu DM.

Clin Cancer Res. 2018 Mar 15;24(6):1389-1401. doi: 10.1158/1078-0432.CCR-17-1958. Epub 2017 Dec 20.

12.

Immunohistopathological characterization and the impact of topical immunomodulatory therapy in oral chronic graft-versus-host disease: A pilot study.

Motta A, Zhan Q, Larson A, Lerman M, Woo SB, Soiffer RJ, Murphy GF, Treister NS.

Oral Dis. 2018 May;24(4):580-590. doi: 10.1111/odi.12813. Epub 2018 Mar 13.

PMID:
29197137
13.

Biological significance of 5-hydroxymethylcytosine in oral epithelial dysplasia and oral squamous cell carcinoma.

Cuevas-Nunez MC, Gomes CBF, Woo SB, Ramsey MR, Chen XL, Xu S, Xu T, Zhan Q, Murphy GF, Lian CG.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Jan;125(1):59-73.e2. doi: 10.1016/j.oooo.2017.06.006. Epub 2017 Jun 16.

PMID:
28743666
14.

IL-1R Type 1-Deficient Mice Demonstrate an Impaired Host Immune Response against Cutaneous Vaccinia Virus Infection.

Tian T, Jin MQ, Dubin K, King SL, Hoetzenecker W, Murphy GF, Chen CA, Kupper TS, Fuhlbrigge RC.

J Immunol. 2017 Jun 1;198(11):4341-4351. doi: 10.4049/jimmunol.1500106. Epub 2017 May 3.

15.

Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity.

Ghosh A, Smith M, James SE, Davila ML, Velardi E, Argyropoulos KV, Gunset G, Perna F, Kreines FM, Levy ER, Lieberman S, Jay HV, Tuckett AZ, Zakrzewski JL, Tan L, Young LF, Takvorian K, Dudakov JA, Jenq RR, Hanash AM, Motta AC, Murphy GF, Liu C, Schietinger A, Sadelain M, van den Brink MR.

Nat Med. 2017 Feb;23(2):242-249. doi: 10.1038/nm.4258. Epub 2017 Jan 9.

16.

5-Hydroxymethylcytosine is a nuclear biomarker to assess biological potential in histologically ambiguous heavily pigmented melanocytic neoplasms.

Lee JJ, Vilain RE, Granter SR, Hu NR, Bresler SC, Xu S, Frank AH, Mihm MC Jr, Saw RP, Fletcher CD, Scolyer RA, Murphy GF, Lian CG.

J Cutan Pathol. 2017 Mar;44(3):249-255. doi: 10.1111/cup.12880. Epub 2017 Feb 6.

PMID:
28032662
17.

Gene expression profiling of anti-CTLA4-treated metastatic melanoma in patients with treatment-induced autoimmunity.

Bresler SC, Min L, Rodig SJ, Walls AC, Xu S, Geng S, Hodi FS, Murphy GF, Lian CG.

Lab Invest. 2017 Feb;97(2):207-216. doi: 10.1038/labinvest.2016.126. Epub 2016 Dec 5.

18.

Targeting melanoma with front-line therapy does not abrogate Nodal-expressing tumor cells.

Hendrix MJ, Kandela I, Mazar AP, Seftor EA, Seftor RE, Margaryan NV, Strizzi L, Murphy GF, Long GV, Scolyer RA.

Lab Invest. 2017 Feb;97(2):176-186. doi: 10.1038/labinvest.2016.107. Epub 2016 Oct 24.

19.

Histopathologic spectrum of hypersensitivity reactions associated with anti-CD52 therapy (alemtuzumab).

Clark SL, Tse JY, Fisher DC, LeBeouf NR, Murphy GF, Kupper TS, Clark RA, Lian CG.

J Cutan Pathol. 2016 Nov;43(11):989-993. doi: 10.1111/cup.12800. Epub 2016 Sep 9. Erratum in: J Cutan Pathol. 2017 Feb;44(2):220.

20.

Toward an Objective Diagnostic Test for Bacterial Cellulitis.

Pallin DJ, Bry L, Dwyer RC, Lipworth AD, Leung DY, Camargo CA Jr, Kupper TS, Filbin MR, Murphy GF.

PLoS One. 2016 Sep 22;11(9):e0162947. doi: 10.1371/journal.pone.0162947. eCollection 2016.

21.

Failure of antibiotics in cellulitis trials: a systematic review and meta-analysis.

Obaitan I, Dwyer R, Lipworth AD, Kupper TS, Camargo CA Jr, Hooper DC, Murphy GF, Pallin DJ.

Am J Emerg Med. 2016 Aug;34(8):1645-52. doi: 10.1016/j.ajem.2016.05.064. Epub 2016 May 26. Review.

PMID:
27344098
22.

Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice.

Shono Y, Docampo MD, Peled JU, Perobelli SM, Velardi E, Tsai JJ, Slingerland AE, Smith OM, Young LF, Gupta J, Lieberman SR, Jay HV, Ahr KF, Porosnicu Rodriguez KA, Xu K, Calarfiore M, Poeck H, Caballero S, Devlin SM, Rapaport F, Dudakov JA, Hanash AM, Gyurkocza B, Murphy GF, Gomes C, Liu C, Moss EL, Falconer SB, Bhatt AS, Taur Y, Pamer EG, van den Brink MRM, Jenq RR.

Sci Transl Med. 2016 May 18;8(339):339ra71. doi: 10.1126/scitranslmed.aaf2311.

23.

TET2 Negatively Regulates Nestin Expression in Human Melanoma.

Gomes CB, Zechin KG, Xu S, Stelini RF, Nishimoto IN, Zhan Q, Xu T, Qin G, Treister NS, Murphy GF, Lian CG.

Am J Pathol. 2016 Jun;186(6):1427-34. doi: 10.1016/j.ajpath.2016.01.020. Epub 2016 Apr 18.

24.

Decreased tumor-infiltrating lymphocytes in nodular melanomas compared with matched superficial spreading melanomas.

Lin RL, Wang TJ, Joyce CJ, Mihm MC Jr, Murphy GF, Lian CG, Lin JY.

Melanoma Res. 2016 Oct;26(5):524-7. doi: 10.1097/CMR.0000000000000253.

PMID:
26974966
25.

The Genetic Evolution of Melanoma.

Lian CG, Murphy GF.

N Engl J Med. 2016 Mar 10;374(10):994-5. doi: 10.1056/NEJMc1515834. No abstract available.

PMID:
26962742
26.

ABCB5-Targeted Chemoresistance Reversal Inhibits Merkel Cell Carcinoma Growth.

Kleffel S, Lee N, Lezcano C, Wilson BJ, Sobolewski K, Saab KR, Mueller H, Zhan Q, Posch C, Elco CP, DoRosario A, Garcia SS, Thakuria M, Wang YE, Wang LC, Murphy GF, Frank MH, Schatton T.

J Invest Dermatol. 2016 Apr;136(4):838-846. doi: 10.1016/j.jid.2015.12.038. Epub 2016 Jan 29.

27.

Codominant Role of Interferon-γ- and Interleukin-17-Producing T Cells During Rejection in Full Facial Transplant Recipients.

Borges TJ, O'Malley JT, Wo L, Murakami N, Smith B, Azzi J, Tripathi S, Lane JD, Bueno EM, Clark RA, Tullius SG, Chandraker A, Lian CG, Murphy GF, Strom TB, Pomahac B, Najafian N, Riella LV.

Am J Transplant. 2016 Jul;16(7):2158-71. doi: 10.1111/ajt.13705. Epub 2016 Apr 7.

28.

Transformation of Face Transplants: Volumetric and Morphologic Graft Changes Resemble Aging After Facial Allotransplantation.

Kueckelhaus M, Turk M, Kumamaru KK, Wo L, Bueno EM, Lian CG, Alhefzi M, Aycart MA, Fischer S, De Girolami U, Murphy GF, Rybicki FJ, Pomahac B.

Am J Transplant. 2016 Mar;16(3):968-78. doi: 10.1111/ajt.13544. Epub 2015 Dec 7.

29.

Epigenetic markers in melanoma.

Guo W, Xu T, Lee JJ, Murphy GF, Lian CG.

Melanoma Manag. 2015 Nov;2(4):367-382. doi: 10.2217/mmt.15.30. Epub 2015 Nov 24. Review.

30.

Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma.

Lee JJ, Cook M, Mihm MC, Xu S, Zhan Q, Wang TJ, Murphy GF, Lian CG.

Oncotarget. 2015 Nov 10;6(35):37995-8004. doi: 10.18632/oncotarget.6062.

31.

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.

Kleffel S, Posch C, Barthel SR, Mueller H, Schlapbach C, Guenova E, Elco CP, Lee N, Juneja VR, Zhan Q, Lian CG, Thomi R, Hoetzenecker W, Cozzio A, Dummer R, Mihm MC Jr, Flaherty KT, Frank MH, Murphy GF, Sharpe AH, Kupper TS, Schatton T.

Cell. 2015 Sep 10;162(6):1242-56. doi: 10.1016/j.cell.2015.08.052.

32.

ABCB5 Identifies Immunoregulatory Dermal Cells.

Schatton T, Yang J, Kleffel S, Uehara M, Barthel SR, Schlapbach C, Zhan Q, Dudeney S, Mueller H, Lee N, de Vries JC, Meier B, Vander Beken S, Kluth MA, Ganss C, Sharpe AH, Waaga-Gasser AM, Sayegh MH, Abdi R, Scharffetter-Kochanek K, Murphy GF, Kupper TS, Frank NY, Frank MH.

Cell Rep. 2015 Sep 8;12(10):1564-74. doi: 10.1016/j.celrep.2015.08.010. Epub 2015 Aug 28.

33.

Cutaneous Squamous Cell Carcinomas of the Lower Extremities Show Distinct Clinical and Pathologic Features.

Solus JF, Murphy GF, Kraft S.

Int J Surg Pathol. 2016 Feb;24(1):29-36. doi: 10.1177/1066896915599058. Epub 2015 Aug 10.

PMID:
26261102
34.

Targeted next-generation sequencing reveals high frequency of mutations in epigenetic regulators across treatment-naïve patient melanomas.

Lee JJ, Sholl LM, Lindeman NI, Granter SR, Laga AC, Shivdasani P, Chin G, Luke JJ, Ott PA, Hodi FS, Mihm MC Jr, Lin JY, Werchniak AE, Haynes HA, Bailey N, Liu R, Murphy GF, Lian CG.

Clin Epigenetics. 2015 Jun 9;7:59. doi: 10.1186/s13148-015-0091-3. eCollection 2015.

35.

Impact of the 2009 AJCC staging guidelines for melanoma on the number of mitotic figures reported by dermatopathologists at one institution.

Larson AR, Rothschild B, Walls AC, Granter SR, Qureshi AA, Murphy GF, Laga AC.

J Cutan Pathol. 2015 Aug;42(8):536-41. doi: 10.1111/cup.12517. Epub 2015 May 26.

PMID:
25929156
36.

Targeting nodal in conjunction with dacarbazine induces synergistic anticancer effects in metastatic melanoma.

Hardy KM, Strizzi L, Margaryan NV, Gupta K, Murphy GF, Scolyer RA, Hendrix MJ.

Mol Cancer Res. 2015 Apr;13(4):670-80. doi: 10.1158/1541-7786.MCR-14-0077. Epub 2015 Mar 12.

37.

Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential.

Yazawa EM, Geddes-Sweeney JE, Cedeno-Laurent F, Walley KC, Barthel SR, Opperman MJ, Liang J, Lin JY, Schatton T, Laga AC, Mihm MC, Qureshi AA, Widlund HR, Murphy GF, Dimitroff CJ.

J Invest Dermatol. 2015 Jul;135(7):1849-1862. doi: 10.1038/jid.2015.95. Epub 2015 Mar 10.

38.

Ponatinib-induced pityriasiform, folliculocentric and ichthyosiform cutaneous toxicities.

Alloo A, Sheu J, Butrynski JE, DeAngelo DJ, George S, Murphy GF, LeBoeuf NR.

Br J Dermatol. 2015 Aug;173(2):574-7. doi: 10.1111/bjd.13692. Epub 2015 Jul 14. No abstract available.

PMID:
25736577
39.

Diagnostic Immunohistochemistry in Cutaneous Neoplasia: An Update.

Compton LA, Murphy GF, Lian CG.

Dermatopathology (Basel). 2015 Apr 8;2(1):15-42. doi: 10.1159/000377698. eCollection 2015 Jan-Mar. Review.

40.

Airway recovery after face transplantation.

Fischer S, Wallins JS, Bueno EM, Kueckelhaus M, Chandawarkar A, Diaz-Siso JR, Larson A, Murphy GF, Annino DJ, Caterson EJ, Pomahac B.

Plast Reconstr Surg. 2014 Dec;134(6):946e-54e. doi: 10.1097/PRS.0000000000000752.

PMID:
25415117
41.

Repigmentation of extensive inflammatory vitiligo with raised borders using early and aggressive treatment.

Gunasekera N, Murphy GF, Sheth VM.

Dermatology. 2015;230(1):11-5. doi: 10.1159/000366197. Epub 2014 Nov 18.

PMID:
25413601
42.

Cutaneous paraneoplastic granulomatous eruptions secondary to metastatic carcinoid tumour.

Cohen JM, Nambudiri VE, Kulke MH, Todd DJ, Murphy GF, LeBoeuf NR.

Br J Dermatol. 2015;172(5):1451-4. doi: 10.1111/bjd.13516. Epub 2015 Mar 27. No abstract available.

PMID:
25388104
43.

Hand transplants and the mandate for tolerance.

Koulmanda M, Pomahac B, Fan Z, Murphy GF, Strom TB.

Curr Opin Organ Transplant. 2014 Dec;19(6):545-51. doi: 10.1097/MOT.0000000000000138. Review.

44.

Nestin depletion induces melanoma matrix metalloproteinases and invasion.

Lee CW, Zhan Q, Lezcano C, Frank MH, Huang J, Larson AR, Lin JY, Wan MT, Lin PI, Ma J, Kleffel S, Schatton T, Lian CG, Murphy GF.

Lab Invest. 2014 Dec;94(12):1382-95. doi: 10.1038/labinvest.2014.130. Epub 2014 Nov 3.

45.

Acute rejection in vascularized composite allotransplantation.

Fischer S, Lian CG, Kueckelhaus M, Strom TB, Edelman ER, Clark RA, Murphy GF, Chandraker AK, Riella LV, Tullius SG, Pomahac B.

Curr Opin Organ Transplant. 2014 Dec;19(6):531-44. doi: 10.1097/MOT.0000000000000140. Review.

PMID:
25333831
46.

Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells.

Hubbard-Lucey VM, Shono Y, Maurer K, West ML, Singer NV, Ziegler CG, Lezcano C, Motta AC, Schmid K, Levi SM, Murphy GF, Liu C, Winkler JD, Amaravadi RK, Rogler G, Dickinson AM, Holler E, van den Brink MR, Cadwell K.

Immunity. 2014 Oct 16;41(4):579-91. doi: 10.1016/j.immuni.2014.09.011. Epub 2014 Oct 9.

47.

Systematic review of molecular mechanism of action of negative-pressure wound therapy.

Glass GE, Murphy GF, Esmaeili A, Lai LM, Nanchahal J.

Br J Surg. 2014 Dec;101(13):1627-36. doi: 10.1002/bjs.9636. Epub 2014 Oct 8. Review.

PMID:
25294112
48.

Novel genetic mutations in a sporadic port-wine stain.

Lian CG, Sholl LM, Zakka LR, O TM, Liu C, Xu S, Stanek E, Garcia E, Jia Y, MacConaill LE, Murphy GF, Waner M, Mihm MC Jr.

JAMA Dermatol. 2014 Dec;150(12):1336-40.

PMID:
25188413
49.

Decrease of 5-hydroxymethylcytosine in rat liver with subchronic exposure to genotoxic carcinogens riddelliine and aristolochic acid.

Lian CG, Xu S, Guo W, Yan J, Frank MY, Liu R, Liu C, Chen Y, Murphy GF, Chen T.

Mol Carcinog. 2015 Nov;54(11):1503-7. doi: 10.1002/mc.22201. Epub 2014 Aug 23.

50.

Merkel cell carcinoma expresses vasculogenic mimicry: demonstration in patients and experimental manipulation in xenografts.

Lezcano C, Kleffel S, Lee N, Larson AR, Zhan Q, DoRosario A, Wang LC, Schatton T, Murphy GF.

Lab Invest. 2014 Oct;94(10):1092-102. doi: 10.1038/labinvest.2014.99. Epub 2014 Aug 11.

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