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Items: 36

1.

miRNA-135b Contributes to Triple Negative Breast Cancer Molecular Heterogeneity: Different Expression Profile in Basal-like Versus non-Basal-like Phenotypes.

Uva P, Cossu-Rocca P, Loi F, Pira G, Murgia L, OrrĂ¹ S, Floris M, Muroni MR, Sanges F, Carru C, Angius A, De Miglio MR.

Int J Med Sci. 2018 Mar 9;15(6):536-548. doi: 10.7150/ijms.23402. eCollection 2018.

2.

EGFR kinase-dependent and kinase-independent roles in clear cell renal cell carcinoma.

Cossu-Rocca P, Muroni MR, Sanges F, Sotgiu G, Asunis A, Tanca L, Onnis D, Pira G, Manca A, Dore S, Uras MG, Ena S, De Miglio MR.

Am J Cancer Res. 2015 Dec 15;6(1):71-83. eCollection 2016.

3.

Analysis of PIK3CA Mutations and Activation Pathways in Triple Negative Breast Cancer.

Cossu-Rocca P, OrrĂ¹ S, Muroni MR, Sanges F, Sotgiu G, Ena S, Pira G, Murgia L, Manca A, Uras MG, Sarobba MG, Urru S, De Miglio MR.

PLoS One. 2015 Nov 5;10(11):e0141763. doi: 10.1371/journal.pone.0141763. eCollection 2015.

4.

HPV infection and triple-negative breast cancers: an Italian case-control study.

Piana AF, Sotgiu G, Muroni MR, Cossu-Rocca P, Castiglia P, De Miglio MR.

Virol J. 2014 Nov 21;11:190. doi: 10.1186/s12985-014-0190-3.

5.

Tyrosine kinase receptor status in endometrial stromal sarcoma: an immunohistochemical and genetic-molecular analysis.

Cossu-Rocca P, Contini M, Uras MG, Muroni MR, Pili F, Carru C, Bosincu L, Massarelli G, Nogales FF, De Miglio MR.

Int J Gynecol Pathol. 2012 Nov;31(6):570-9. doi: 10.1097/PGP.0b013e31824fe289.

PMID:
23018215
6.

Evaluation of methylation degree from formalin-fixed paraffin-embedded DNA extract by field-amplified sample injection capillary electrophoresis with UV detection.

Zinellu A, Sotgia S, De Murtas V, Cossu-Rocca P, De Miglio MR, Muroni MR, Mura A, Uras MG, Contini M, Deiana L, Carru C.

Anal Bioanal Chem. 2011 Jan;399(3):1181-6. doi: 10.1007/s00216-010-4417-x. Epub 2010 Nov 21.

PMID:
21104070
7.

SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis.

Calvisi DF, Ladu S, Pinna F, Frau M, Tomasi ML, Sini M, Simile MM, Bonelli P, Muroni MR, Seddaiu MA, Lim DS, Feo F, Pascale RM.

Gastroenterology. 2009 Nov;137(5):1816-26.e1-10. doi: 10.1053/j.gastro.2009.08.005. Epub 2009 Aug 15.

PMID:
19686743
8.

The degradation of cell cycle regulators by SKP2/CKS1 ubiquitin ligase is genetically controlled in rodent liver cancer and contributes to determine the susceptibility to the disease.

Calvisi DF, Pinna F, Ladu S, Muroni MR, Frau M, Demartis I, Tomasi ML, Sini M, Simile MM, Seddaiu MA, Feo F, Pascale RM.

Int J Cancer. 2010 Mar 1;126(5):1275-81. doi: 10.1002/ijc.24650.

9.

Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC.

Calvisi DF, Pinna F, Ladu S, Pellegrino R, Simile MM, Frau M, De Miglio MR, Tomasi ML, Sanna V, Muroni MR, Feo F, Pascale RM.

Gut. 2009 May;58(5):679-87. doi: 10.1136/gut.2008.152652. Epub 2009 Jan 9.

PMID:
19136513
10.

Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control.

Calvisi DF, Pinna F, Pellegrino R, Sanna V, Sini M, Daino L, Simile MM, De Miglio MR, Frau M, Tomasi ML, Seddaiu MA, Muroni MR, Feo F, Pascale RM.

Int J Cancer. 2008 Nov 1;123(9):2057-64. doi: 10.1002/ijc.23720.

11.

Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease.

Calvisi DF, Pinna F, Ladu S, Pellegrino R, Muroni MR, Simile MM, Frau M, Tomasi ML, De Miglio MR, Seddaiu MA, Daino L, Sanna V, Feo F, Pascale RM.

Carcinogenesis. 2008 Aug;29(8):1639-47. doi: 10.1093/carcin/bgn155. Epub 2008 Jun 25.

PMID:
18579559
12.

Dual-specificity phosphatase 1 ubiquitination in extracellular signal-regulated kinase-mediated control of growth in human hepatocellular carcinoma.

Calvisi DF, Pinna F, Meloni F, Ladu S, Pellegrino R, Sini M, Daino L, Simile MM, De Miglio MR, Virdis P, Frau M, Tomasi ML, Seddaiu MA, Muroni MR, Feo F, Pascale RM.

Cancer Res. 2008 Jun 1;68(11):4192-200. doi: 10.1158/0008-5472.CAN-07-6157.

13.

Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis.

Calvisi DF, Simile MM, Ladu S, Pellegrino R, De Murtas V, Pinna F, Tomasi ML, Frau M, Virdis P, De Miglio MR, Muroni MR, Pascale RM, Feo F.

Int J Cancer. 2007 Dec 1;121(11):2410-20.

14.

Identification and chromosome mapping of loci predisposing to colorectal cancer that control Wnt/beta-catenin pathway and progression of early lesions in the rat.

De Miglio MR, Virdis P, Calvisi DF, Mele D, Muroni MR, Frau M, Pinna F, Tomasi ML, Simile MM, Pascale RM, Feo F.

Carcinogenesis. 2007 Nov;28(11):2367-74. Epub 2007 May 17.

PMID:
17510081
15.

Mapping a sex hormone-sensitive gene determining female resistance to liver carcinogenesis in a congenic F344.BN-Hcs4 rat.

De Miglio MR, Virdis P, Calvisi DF, Frau M, Muroni MR, Simile MM, Daino L, Careddu GM, Sanna-Passino E, Pascale RM, Feo F.

Cancer Res. 2006 Nov 1;66(21):10384-90.

16.

Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer.

Pascale RM, Simile MM, Calvisi DF, Frau M, Muroni MR, Seddaiu MA, Daino L, Muntoni MD, De Miglio MR, Thorgeirsson SS, Feo F.

Hepatology. 2005 Dec;42(6):1310-9.

PMID:
16317707
17.

Hepatocellular carcinoma as a complex polygenic disease. Interpretive analysis of recent developments on genetic predisposition.

Feo F, De Miglio MR, Simile MM, Muroni MR, Calvisi DF, Frau M, Pascale RM.

Biochim Biophys Acta. 2006 Apr;1765(2):126-47. Epub 2005 Sep 15. Review.

PMID:
16216419
18.

Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-{kappa}B and Mat1A genes in the early stages of rat liver carcinogenesis.

Simile MM, Pagnan G, Pastorino F, Brignole C, De Miglio MR, Muroni MR, Asara G, Frau M, Seddaiu MA, Calvisi DF, Feo F, Ponzoni M, Pascale RM.

Carcinogenesis. 2005 Feb;26(2):417-27. Epub 2004 Oct 21.

PMID:
15498786
19.

Polygenic control of hepatocarcinogenesis in Copenhagen x F344 rats.

De Miglio MR, Pascale RM, Simile MM, Muroni MR, Virdis P, Kwong KM, Wong LK, Bosinco GM, Pulina FR, Calvisi DF, Frau M, Wood GA, Archer MC, Feo F.

Int J Cancer. 2004 Aug 10;111(1):9-16.

20.

Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells.

Simile MM, De Miglio MR, Muroni MR, Frau M, Asara G, Serra S, Muntoni MD, Seddaiu MA, Daino L, Feo F, Pascale RM.

Carcinogenesis. 2004 Mar;25(3):333-41. Epub 2003 Nov 6.

PMID:
14604889
21.

Phenotypic reversion of rat neoplastic liver nodules is under genetic control.

De Miglio MR, Simile MM, Muroni MR, Calvisi DF, Virdis P, Asara G, Frau M, Bosinco GM, Seddaiu MA, Daino L, Feo F, Pascale RM.

Int J Cancer. 2003 May 20;105(1):70-5.

22.

Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis.

De Miglio MR, Pascale RM, Simile MM, Muroni MR, Calvisi DF, Virdis P, Bosinco GM, Frau M, Seddaiu MA, Ladu S, Feo F.

Cancer Res. 2002 Aug 1;62(15):4459-63.

23.

Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis.

Pascale RM, Simile MM, De Miglio MR, Muroni MR, Calvisi DF, Asara G, Casabona D, Frau M, Seddaiu MA, Feo F.

Hepatology. 2002 Jun;35(6):1341-50.

PMID:
12029619
24.

Frequent loss of heterozygosity at the Hcr1 (hepatocarcinogenesis resistance) locus on chromosome 10 in primary hepatocellular carcinomas from LFF1 rat strain.

De Miglio MR, Muroni MR, Simile MM, Virdis P, Asara G, Frau M, Calvisi DF, Seddaiu MA, Pascale RM, Feo F.

Hepatology. 2001 May;33(5):1110-7.

PMID:
11343238
25.

5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication.

Simile MM, Banni S, Angioni E, Carta G, De Miglio MR, Muroni MR, Calvisi DF, Carru A, Pascale RM, Feo F.

J Hepatol. 2001 Mar;34(3):386-94.

PMID:
11322199
26.

Genetic alterations in liver carcinogenesis: implications for new preventive and therapeutic strategies.

Feo F, Pascale RM, Simile MM, De Miglio MR, Muroni MR, Calvisi D.

Crit Rev Oncog. 2000;11(1):19-62. Review.

PMID:
10795626
27.

Implication of Bcl-2 family genes in basal and D-amphetamine-induced apoptosis in preneoplastic and neoplastic rat liver lesions.

De Miglio MR, Muroni MR, Simile MM, Calvisi DF, Tolu P, Deiana L, Carru A, Bonelli G, Feo F, Pascale RM.

Hepatology. 2000 Apr;31(4):956-65.

PMID:
10733553
28.

Identification of genetic loci controlling hepatocarcinogenesis on rat chromosomes 7 and 10.

De Miglio MR, Canzian F, Pascale RM, Simile MM, Muroni MR, Calvisi D, Romeo G, Feo F.

Cancer Res. 1999 Sep 15;59(18):4651-7.

29.

Correlation of c-myc overexpression and amplification with progression of preneoplastic liver lesions to malignancy in the poorly susceptible Wistar rat strain.

De Miglio MR, Simile MM, Muroni MR, Pusceddu S, Calvisi D, Carru A, Seddaiu MA, Daino L, Deiana L, Pascale RM, Feo F.

Mol Carcinog. 1999 May;25(1):21-9.

PMID:
10331741
30.

Transferrin and transferrin receptor gene expression and iron uptake in hepatocellular carcinoma in the rat.

Pascale RM, De Miglio MR, Muroni MR, Simile MM, Daino L, Seddaiu MA, Pusceddu S, Gaspa L, Calvisi D, Manenti G, Feo F.

Hepatology. 1998 Feb;27(2):452-61.

PMID:
9462644
31.

c-myc amplification in pre-malignant and malignant lesions induced in rat liver by the resistant hepatocyte model.

Pascale RM, De Miglio MR, Muroni MR, Simile MM, Daino L, Seddaiu MA, Nufris A, Gaspa L, Deiana L, Feo F.

Int J Cancer. 1996 Sep 27;68(1):136-42.

32.

The BN rat strain carries dominant hepatocarcinogen resistance loci.

Pascale RM, Simile MM, DeMiglio MR, Muroni MR, Gaspa L, Dragani TA, Feo F.

Carcinogenesis. 1996 Aug;17(8):1765-8.

PMID:
8761440
33.

Persistent chemopreventive effect of S-adenosyl-L-methionine on the development of liver putative preneoplastic lesions induced by thiobenzamide in diethylnitrosamine-initiated rats.

Simile MM, Saviozzi M, De Miglio MR, Muroni MR, Nufris A, Pascale RM, Malvaldi G, Feo F.

Carcinogenesis. 1996 Jul;17(7):1533-7.

PMID:
8706260
34.

Inhibition by dehydroepiandrosterone of growth and progression of persistent liver nodules in experimental rat liver carcinogenesis.

Simile M, Pascale RM, De Miglio MR, Nufris A, Daino L, Seddaiu MA, Muroni MR, Rao KN, Feo F.

Int J Cancer. 1995 Jul 17;62(2):210-5.

PMID:
7622298
35.

Inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase activity and gene expression by dehydroepiandrosterone in preneoplastic liver nodules.

Pascale RM, Simile MM, De Miglio MR, Nufris A, Seddaiu MA, Muroni MR, Danni O, Rao KN, Feo F.

Carcinogenesis. 1995 Jul;16(7):1537-42.

PMID:
7614686
36.

l-5-formyltetrahydrofolate and l-5-methyltetrahydrofolate rescue in L1210 leukemia treated with high methotrexate doses.

Simile MM, DeMiglio MR, Nufris A, Pascale RM, Muroni MR, Feo F.

Res Commun Chem Pathol Pharmacol. 1993 Aug;81(2):251-4.

PMID:
8210704

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