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Items: 1 to 50 of 73

1.

IκB-ζ Expression Requires Both TYK2/STAT3 Activity and IL-17-Regulated mRNA Stabilization.

Muromoto R, Tawa K, Ohgakiuchi Y, Sato A, Saino Y, Hirashima K, Minoguchi H, Kitai Y, Kashiwakura JI, Shimoda K, Oritani K, Matsuda T.

Immunohorizons. 2019 May 16;3(5):172-185. doi: 10.4049/immunohorizons.1900023.

PMID:
31356171
2.

STAP-2 positively regulates FcεRI-mediated basophil activation and basophil-dependent allergic inflammatory reactions.

Kashiwakura JI, Yamashita S, Yoshihara M, Inui K, Saitoh K, Sekine Y, Muromoto R, Kitai Y, Oritani K, Matsuda T.

Int Immunol. 2019 Apr 26;31(5):349-356. doi: 10.1093/intimm/dxz013.

PMID:
30726917
3.

Synthesis of Chiral cis-Cyclopropane Bearing Indole and Chromone as Potential TNFα Inhibitors.

Kanada R, Tanabe M, Muromoto R, Sato Y, Kuwahara T, Fukuda H, Arisawa M, Matsuda T, Watanabe M, Shuto S.

J Org Chem. 2018 Aug 3;83(15):7672-7682. doi: 10.1021/acs.joc.8b00466. Epub 2018 Jul 24.

PMID:
30004223
4.

STAP-2 protein promotes prostate cancer growth by enhancing epidermal growth factor receptor stabilization.

Kitai Y, Iwakami M, Saitoh K, Togi S, Isayama S, Sekine Y, Muromoto R, Kashiwakura JI, Yoshimura A, Oritani K, Matsuda T.

J Biol Chem. 2017 Nov 24;292(47):19392-19399. doi: 10.1074/jbc.M117.802884. Epub 2017 Oct 6.

5.

Anti-IL-17A blocking antibody reduces cyclosporin A-induced relapse in experimental autoimmune encephalomyelitis mice.

Saitoh K, Kon S, Nakatsuru T, Inui K, Ihara T, Matsumoto N, Kitai Y, Muromoto R, Matsuda T.

Biochem Biophys Rep. 2016 Aug 26;8:139-145. doi: 10.1016/j.bbrep.2016.08.021. eCollection 2016 Dec.

6.

Biochanin A enhances RORγ activity through STAT3-mediated recruitment of NCOA1.

Takahashi M, Muromoto R, Kojima H, Takeuchi S, Kitai Y, Kashiwakura JI, Matsuda T.

Biochem Biophys Res Commun. 2017 Aug 5;489(4):503-508. doi: 10.1016/j.bbrc.2017.05.181. Epub 2017 Jun 1.

7.

A Novel α9 Integrin Ligand, XCL1/Lymphotactin, Is Involved in the Development of Murine Models of Autoimmune Diseases.

Matsumoto N, Kon S, Nakatsuru T, Miyashita T, Inui K, Saitoh K, Kitai Y, Muromoto R, Kashiwakura JI, Uede T, Matsuda T.

J Immunol. 2017 Jul 1;199(1):82-90. doi: 10.4049/jimmunol.1601329. Epub 2017 May 26.

8.

STAP-2 interacts with Pyk2 and enhances Pyk2 activity in T-cells.

Saitoh K, Tsuchiya T, Kashiwakura JI, Muromoto R, Kitai Y, Sekine Y, Oritani K, Matsuda T.

Biochem Biophys Res Commun. 2017 Jun 17;488(1):81-87. doi: 10.1016/j.bbrc.2017.05.010. Epub 2017 May 3.

9.

Design and Synthesis of Cyclopropane Congeners of Resolvin E2, an Endogenous Proresolving Lipid Mediator, as Its Stable Equivalents.

Fukuda H, Muromoto R, Takakura Y, Ishimura K, Kanada R, Fushihara D, Tanabe M, Matsubara K, Hirao T, Hirashima K, Abe H, Arisawa M, Matsuda T, Shuto S.

Org Lett. 2016 Dec 16;18(24):6224-6227. Epub 2016 Nov 28.

PMID:
27978690
10.

A New STAT3-binding Partner, ARL3, Enhances the Phosphorylation and Nuclear Accumulation of STAT3.

Togi S, Muromoto R, Hirashima K, Kitai Y, Okayama T, Ikeda O, Matsumoto N, Kon S, Sekine Y, Oritani K, Matsuda T.

J Biol Chem. 2016 May 20;291(21):11161-71. doi: 10.1074/jbc.M116.724849. Epub 2016 Apr 5.

11.

IL-17A plays a central role in the expression of psoriasis signature genes through the induction of IκB-ζ in keratinocytes.

Muromoto R, Hirao T, Tawa K, Hirashima K, Kon S, Kitai Y, Matsuda T.

Int Immunol. 2016 Sep;28(9):443-52. doi: 10.1093/intimm/dxw011. Epub 2016 Mar 3.

12.

Caspase-dependent cleavage regulates protein levels of Epstein-Barr virus-derived latent membrane protein 1.

Togi S, Hatano Y, Muromoto R, Kawanishi E, Ikeda O, Hirashima K, Kon S, Kitai Y, Yasui T, Oritani K, Matsuda T.

FEBS Lett. 2016 Mar;590(6):808-18. doi: 10.1002/1873-3468.12119. Epub 2016 Mar 4.

13.

Signal transducer and activator of transcription 3 regulation by novel binding partners.

Matsuda T, Muromoto R, Sekine Y, Togi S, Kitai Y, Kon S, Oritani K.

World J Biol Chem. 2015 Nov 26;6(4):324-32. doi: 10.4331/wjbc.v6.i4.324. Review.

14.

CCR7 is involved in BCR-ABL/STAP-2-mediated cell growth in hematopoietic Ba/F3 cells.

Kubo K, Iwakami M, Muromoto R, Inagaki T, Kitai Y, Kon S, Sekine Y, Oritani K, Matsuda T.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):825-31. doi: 10.1016/j.bbrc.2015.06.020. Epub 2015 Jun 21.

15.

Kaposi's sarcoma-associated herpesvirus-encoded LANA associates with glucocorticoid receptor and enhances its transcriptional activities.

Togi S, Nakasuji M, Muromoto R, Ikeda O, Okabe K, Kitai Y, Kon S, Oritani K, Matsuda T.

Biochem Biophys Res Commun. 2015 Jul 31;463(3):395-400. doi: 10.1016/j.bbrc.2015.05.080. Epub 2015 May 29.

16.

STAP-2 Protein Expression in B16F10 Melanoma Cells Positively Regulates Protein Levels of Tyrosinase, Which Determines Organs to Infiltrate in the Body.

Sekine Y, Togi S, Muromoto R, Kon S, Kitai Y, Yoshimura A, Oritani K, Matsuda T.

J Biol Chem. 2015 Jul 10;290(28):17462-73. doi: 10.1074/jbc.M115.658575. Epub 2015 May 28.

17.

PML suppresses IL-6-induced STAT3 activation by interfering with STAT3 and HDAC3 interaction.

Kato M, Muromoto R, Togi S, Iwakami M, Kitai Y, Kon S, Oritani K, Matsuda T.

Biochem Biophys Res Commun. 2015 May 29;461(2):366-71. doi: 10.1016/j.bbrc.2015.04.040. Epub 2015 Apr 17.

18.

Isoflavones enhance interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ.

Kojima H, Takeda Y, Muromoto R, Takahashi M, Hirao T, Takeuchi S, Jetten AM, Matsuda T.

Toxicology. 2015 Mar 2;329:32-9. doi: 10.1016/j.tox.2015.01.007. Epub 2015 Jan 9.

19.

The novel α4B murine α4 integrin protein splicing variant inhibits α4 protein-dependent cell adhesion.

Kouro H, Kon S, Matsumoto N, Miyashita T, Kakuchi A, Ashitomi D, Saitoh K, Nakatsuru T, Togi S, Muromoto R, Matsuda T.

J Biol Chem. 2014 Jun 6;289(23):16389-98. doi: 10.1074/jbc.M114.553610. Epub 2014 Apr 22.

20.

Signal-transducing adaptor protein-2 regulates macrophage migration into inflammatory sites during dextran sodium sulfate induced colitis.

Fujita N, Oritani K, Ichii M, Yokota T, Saitoh N, Okuzaki D, Sekine Y, Kon S, Muromoto R, Saitoh K, Yoshimura A, Matsuda T, Kanakura Y.

Eur J Immunol. 2014 Jun;44(6):1791-801. doi: 10.1002/eji.201344239. Epub 2014 Apr 15.

21.

Signal-transducing adaptor protein-2 controls the IgE-mediated, mast cell-mediated anaphylactic responses.

Sekine Y, Nishida K, Yamasaki S, Muromoto R, Kon S, Kashiwakura J, Saitoh K, Togi S, Yoshimura A, Oritani K, Matsuda T.

J Immunol. 2014 Apr 15;192(8):3488-95. doi: 10.4049/jimmunol.1300886. Epub 2014 Mar 10.

22.

Tyk2 is a therapeutic target for psoriasis-like skin inflammation.

Ishizaki M, Muromoto R, Akimoto T, Sekine Y, Kon S, Diwan M, Maeda H, Togi S, Shimoda K, Oritani K, Matsuda T.

Int Immunol. 2014 May;26(5):257-67. doi: 10.1093/intimm/dxt062. Epub 2013 Dec 17.

23.

Jun activation domain-binding protein 1 (JAB1) is required for the optimal response to interferons.

Muromoto R, Nakajima M, Hirashima K, Hirao T, Kon S, Shimoda K, Oritani K, Matsuda T.

J Biol Chem. 2013 Oct 25;288(43):30969-79. doi: 10.1074/jbc.M113.485847. Epub 2013 Sep 16.

24.

Y14 positively regulates TNF-α-induced NF-κB transcriptional activity via interacting RIP1 and TRADD beyond an exon junction complex protein.

Togi S, Shiga K, Muromoto R, Kato M, Souma Y, Sekine Y, Kon S, Oritani K, Matsuda T.

J Immunol. 2013 Aug 1;191(3):1436-44. doi: 10.4049/jimmunol.1300501. Epub 2013 Jul 1.

25.

[Moleculary targeted therapy for JAK/STAT signaling].

Matsuda T, Kon S, Muromoto R.

Nihon Rinsho. 2012 Nov;70 Suppl 8:45-51. Japanese. No abstract available.

PMID:
23513810
26.

[Death domain-associated protein (DAXX)-mediated regulation of transcription and cell death].

Muromoto R.

Yakugaku Zasshi. 2012;132(9):979-84. Review. Japanese.

27.

Signal-transducing adaptor protein-2 modulates Fas-mediated T cell apoptosis by interacting with caspase-8.

Sekine Y, Yamamoto C, Kakisaka M, Muromoto R, Kon S, Ashitomi D, Fujita N, Yoshimura A, Oritani K, Matsuda T.

J Immunol. 2012 Jun 15;188(12):6194-204. doi: 10.4049/jimmunol.1103467. Epub 2012 May 18.

28.

Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ.

Kojima H, Muromoto R, Takahashi M, Takeuchi S, Takeda Y, Jetten AM, Matsuda T.

Toxicol Appl Pharmacol. 2012 Mar 15;259(3):338-45. doi: 10.1016/j.taap.2012.01.011. Epub 2012 Jan 24.

29.

STAP-2 interacts with and modulates BCR-ABL-mediated tumorigenesis.

Sekine Y, Ikeda O, Mizushima A, Ueno Y, Muromoto R, Yoshimura A, Kanakura Y, Oritani K, Matsuda T.

Oncogene. 2012 Oct 4;31(40):4384-96. doi: 10.1038/onc.2011.604. Epub 2012 Jan 9.

30.

PDLIM2 inhibits T helper 17 cell development and granulomatous inflammation through degradation of STAT3.

Tanaka T, Yamamoto Y, Muromoto R, Ikeda O, Sekine Y, Grusby MJ, Kaisho T, Matsuda T.

Sci Signal. 2011 Dec 6;4(202):ra85. doi: 10.1126/scisignal.2001637.

31.

Krüppel-associated box-associated protein 1 negatively regulates TNF-α-induced NF-κB transcriptional activity by influencing the interactions among STAT3, p300, and NF-κB/p65.

Kamitani S, Togi S, Ikeda O, Nakasuji M, Sakauchi A, Sekine Y, Muromoto R, Oritani K, Matsuda T.

J Immunol. 2011 Sep 1;187(5):2476-83. doi: 10.4049/jimmunol.1003243. Epub 2011 Aug 1.

32.

Tyk2 deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice.

Ishizaki M, Muromoto R, Akimoto T, Ohshiro Y, Takahashi M, Sekine Y, Maeda H, Shimoda K, Oritani K, Matsuda T.

Int Immunol. 2011 Sep;23(9):575-82. doi: 10.1093/intimm/dxr057. Epub 2011 Jul 16.

33.

Involvement of tyrosine kinase-2 in both the IL-12/Th1 and IL-23/Th17 axes in vivo.

Ishizaki M, Akimoto T, Muromoto R, Yokoyama M, Ohshiro Y, Sekine Y, Maeda H, Shimoda K, Oritani K, Matsuda T.

J Immunol. 2011 Jul 1;187(1):181-9. doi: 10.4049/jimmunol.1003244. Epub 2011 May 23.

34.

Noncanonical K27-linked polyubiquitination of TIEG1 regulates Foxp3 expression and tumor growth.

Peng DJ, Zeng M, Muromoto R, Matsuda T, Shimoda K, Subramaniam M, Spelsberg TC, Wei WZ, Venuprasad K.

J Immunol. 2011 May 15;186(10):5638-47. doi: 10.4049/jimmunol.1003801. Epub 2011 Apr 6.

35.

Zipper-interacting protein kinase (ZIPK) modulates canonical Wnt/beta-catenin signaling through interaction with Nemo-like kinase and T-cell factor 4 (NLK/TCF4).

Togi S, Ikeda O, Kamitani S, Nakasuji M, Sekine Y, Muromoto R, Nanbo A, Oritani K, Kawai T, Akira S, Matsuda T.

J Biol Chem. 2011 May 27;286(21):19170-7. doi: 10.1074/jbc.M110.189829. Epub 2011 Mar 30.

36.

Involvement of STAP-2 in Brk-mediated phosphorylation and activation of STAT5 in breast cancer cells.

Ikeda O, Mizushima A, Sekine Y, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T.

Cancer Sci. 2011 Apr;102(4):756-61. doi: 10.1111/j.1349-7006.2010.01842.x. Epub 2011 Jan 23.

37.

Functional involvement of Daxx in gp130-mediated cell growth and survival in BaF3 cells.

Muromoto R, Kuroda M, Togi S, Sekine Y, Nanbo A, Shimoda K, Oritani K, Matsuda T.

Eur J Immunol. 2010 Dec;40(12):3570-80. doi: 10.1002/eji.201040688. Epub 2010 Nov 11.

38.

Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells.

Ikeda O, Sekine Y, Mizushima A, Nakasuji M, Miyasaka Y, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T.

J Biol Chem. 2010 Dec 3;285(49):38093-103. doi: 10.1074/jbc.M110.162388. Epub 2010 Oct 7.

39.

BS69 cooperates with TRAF3 in the regulation of Epstein-Barr virus-derived LMP1/CTAR1-induced NF-kappaB activation.

Ikeda O, Miyasaka Y, Yoshida R, Mizushima A, Oritani K, Sekine Y, Kuroda M, Yasui T, Fujimuro M, Muromoto R, Nanbo A, Matsuda T.

FEBS Lett. 2010 Mar 5;584(5):865-72. doi: 10.1016/j.febslet.2010.01.060. Epub 2010 Feb 5.

40.

Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells.

Sekine Y, Ikeda O, Tsuji S, Yamamoto C, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T.

J Immunol. 2009 Dec 15;183(12):7966-74. doi: 10.4049/jimmunol.0902096.

41.
42.

The protein content of an adaptor protein, STAP-2 is controlled by E3 ubiquitin ligase Cbl.

Sekine Y, Yamamoto C, Ikeda O, Muromoto R, Nanbo A, Oritani K, Yoshimura A, Matsuda T.

Biochem Biophys Res Commun. 2009 Jun 26;384(2):187-92. doi: 10.1016/j.bbrc.2009.04.109. Epub 2009 May 3.

43.

STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation.

Ikeda O, Miyasaka Y, Sekine Y, Mizushima A, Muromoto R, Nanbo A, Yoshimura A, Matsuda T.

Biochem Biophys Res Commun. 2009 Jun 19;384(1):71-5. doi: 10.1016/j.bbrc.2009.04.076. Epub 2009 Apr 23.

44.

BS69 negatively regulates the canonical NF-kappaB activation induced by Epstein-Barr virus-derived LMP1.

Ikeda O, Sekine Y, Mizushima A, Oritani K, Yasui T, Fujimuro M, Muromoto R, Nanbo A, Matsuda T.

FEBS Lett. 2009 May 19;583(10):1567-74. doi: 10.1016/j.febslet.2009.04.022. Epub 2009 Apr 18.

45.

The exon-junction complex proteins, Y14 and MAGOH regulate STAT3 activation.

Muromoto R, Taira N, Ikeda O, Shiga K, Kamitani S, Togi S, Kawakami S, Sekine Y, Nanbo A, Oritani K, Matsuda T.

Biochem Biophys Res Commun. 2009 Apr 24;382(1):63-8. doi: 10.1016/j.bbrc.2009.02.127. Epub 2009 Feb 28.

46.

HDAC3 influences phosphorylation of STAT3 at serine 727 by interacting with PP2A.

Togi S, Kamitani S, Kawakami S, Ikeda O, Muromoto R, Nanbo A, Matsuda T.

Biochem Biophys Res Commun. 2009 Feb 6;379(2):616-20. doi: 10.1016/j.bbrc.2008.12.132. Epub 2009 Jan 1.

47.

Epstein-Barr virus-derived EBNA2 regulates STAT3 activation.

Muromoto R, Ikeda O, Okabe K, Togi S, Kamitani S, Fujimuro M, Harada S, Oritani K, Matsuda T.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):439-43. doi: 10.1016/j.bbrc.2008.11.053. Epub 2008 Nov 24.

48.
49.

STAP-2 negatively regulates both canonical and noncanonical NF-kappaB activation induced by Epstein-Barr virus-derived latent membrane protein 1.

Ikeda O, Sekine Y, Yasui T, Oritani K, Sugiyma K, Muromoto R, Ohbayashi N, Yoshimura A, Matsuda T.

Mol Cell Biol. 2008 Aug;28(16):5027-42. doi: 10.1128/MCB.00194-08. Epub 2008 Jun 23.

50.

Physical and functional interactions between ZIP kinase and UbcH5.

Ohbayashi N, Okada K, Kawakami S, Togi S, Sato N, Ikeda O, Kamitani S, Muromoto R, Sekine Y, Kawai T, Akira S, Matsuda T.

Biochem Biophys Res Commun. 2008 Aug 8;372(4):708-12. doi: 10.1016/j.bbrc.2008.05.113. Epub 2008 Jun 2.

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