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Items: 16


Temporal evolution of the microbiome, immune system, and epigenome with disease progression in ALS mice.

Figueroa-Romero C, Guo K, Murdock BJ, Paez-Colasante X, Bassis CM, Mikhail KA, Raue KD, Evans MC, Taubman GF, McDermott AJ, O'Brien PD, Savelieff MG, Hur J, Feldman EL.

Dis Model Mech. 2019 Oct 9. pii: dmm.041947. doi: 10.1242/dmm.041947. [Epub ahead of print]


Toll-like receptors and inflammation in metabolic neuropathy; a role in early versus late disease?

Elzinga S, Murdock BJ, Guo K, Hayes JM, Tabbey MA, Hur J, Feldman EL.

Exp Neurol. 2019 Oct;320:112967. doi: 10.1016/j.expneurol.2019.112967. Epub 2019 May 28.


Transcriptional networks of progressive diabetic peripheral neuropathy in the db/db mouse model of type 2 diabetes: An inflammatory story.

Hinder LM, Murdock BJ, Park M, Bender DE, O'Brien PD, Rumora AE, Hur J, Feldman EL.

Exp Neurol. 2018 Jul;305:33-43. doi: 10.1016/j.expneurol.2018.03.011. Epub 2018 Mar 14.


Correlation of Peripheral Immunity With Rapid Amyotrophic Lateral Sclerosis Progression.

Murdock BJ, Zhou T, Kashlan SR, Little RJ, Goutman SA, Feldman EL.

JAMA Neurol. 2017 Dec 1;74(12):1446-1454. doi: 10.1001/jamaneurol.2017.2255.


Increased ratio of circulating neutrophils to monocytes in amyotrophic lateral sclerosis.

Murdock BJ, Bender DE, Kashlan SR, Figueroa-Romero C, Backus C, Callaghan BC, Goutman SA, Feldman EL.

Neurol Neuroimmunol Neuroinflamm. 2016 Jun 1;3(4):e242. doi: 10.1212/NXI.0000000000000242. eCollection 2016 Aug.


Local GM-CSF-Dependent Differentiation and Activation of Pulmonary Dendritic Cells and Macrophages Protect against Progressive Cryptococcal Lung Infection in Mice.

Chen GH, Teitz-Tennenbaum S, Neal LM, Murdock BJ, Malachowski AN, Dils AJ, Olszewski MA, Osterholzer JJ.

J Immunol. 2016 Feb 15;196(4):1810-21. doi: 10.4049/jimmunol.1501512. Epub 2016 Jan 11.


Local origin of mesenchymal cells in a murine orthotopic lung transplantation model of bronchiolitis obliterans.

Mimura T, Walker N, Aoki Y, Manning CM, Murdock BJ, Myers JL, Lagstein A, Osterholzer JJ, Lama VN.

Am J Pathol. 2015 Jun;185(6):1564-74. doi: 10.1016/j.ajpath.2015.03.002. Epub 2015 Apr 4.


The dual roles of immunity in ALS: injury overrides protection.

Murdock BJ, Bender DE, Segal BM, Feldman EL.

Neurobiol Dis. 2015 May;77:1-12. doi: 10.1016/j.nbd.2015.02.017. Epub 2015 Feb 26. Review.


Early or late IL-10 blockade enhances Th1 and Th17 effector responses and promotes fungal clearance in mice with cryptococcal lung infection.

Murdock BJ, Teitz-Tennenbaum S, Chen GH, Dils AJ, Malachowski AN, Curtis JL, Olszewski MA, Osterholzer JJ.

J Immunol. 2014 Oct 15;193(8):4107-16. doi: 10.4049/jimmunol.1400650. Epub 2014 Sep 15.


Interleukin-17A enhances host defense against cryptococcal lung infection through effects mediated by leukocyte recruitment, activation, and gamma interferon production.

Murdock BJ, Huffnagle GB, Olszewski MA, Osterholzer JJ.

Infect Immun. 2014 Mar;82(3):937-48. doi: 10.1128/IAI.01477-13. Epub 2013 Dec 9.


Implicating exudate macrophages and Ly-6C(high) monocytes in CCR2-dependent lung fibrosis following gene-targeted alveolar injury.

Osterholzer JJ, Olszewski MA, Murdock BJ, Chen GH, Erb-Downward JR, Subbotina N, Browning K, Lin Y, Morey RE, Dayrit JK, Horowitz JC, Simon RH, Sisson TH.

J Immunol. 2013 Apr 1;190(7):3447-57. doi: 10.4049/jimmunol.1200604. Epub 2013 Mar 6.


Early induction of CCL7 downstream of TLR9 signaling promotes the development of robust immunity to cryptococcal infection.

Qiu Y, Zeltzer S, Zhang Y, Wang F, Chen GH, Dayrit J, Murdock BJ, Bhan U, Toews GB, Osterholzer JJ, Standiford TJ, Olszewski MA.

J Immunol. 2012 Apr 15;188(8):3940-8. doi: 10.4049/jimmunol.1103053. Epub 2012 Mar 14.


PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.

Osterholzer JJ, Christensen PJ, Lama V, Horowitz JC, Hattori N, Subbotina N, Cunningham A, Lin Y, Murdock BJ, Morey RE, Olszewski MA, Lawrence DA, Simon RH, Sisson TH.

J Pathol. 2012 Oct;228(2):170-80. doi: 10.1002/path.3992. Epub 2012 Jun 6.


Interleukin-17 drives pulmonary eosinophilia following repeated exposure to Aspergillus fumigatus conidia.

Murdock BJ, Falkowski NR, Shreiner AB, Sadighi Akha AA, McDonald RA, White ES, Toews GB, Huffnagle GB.

Infect Immun. 2012 Apr;80(4):1424-36. doi: 10.1128/IAI.05529-11. Epub 2012 Jan 17.


Repeated exposure to Aspergillus fumigatus conidia results in CD4+ T cell-dependent and -independent pulmonary arterial remodeling in a mixed Th1/Th2/Th17 microenvironment that requires interleukin-4 (IL-4) and IL-10.

Shreiner AB, Murdock BJ, Sadighi Akha AA, Falkowski NR, Christensen PJ, White ES, Hogaboam CM, Huffnagle GB.

Infect Immun. 2012 Jan;80(1):388-97. doi: 10.1128/IAI.05530-11. Epub 2011 Nov 7.


Coevolution of TH1, TH2, and TH17 responses during repeated pulmonary exposure to Aspergillus fumigatus conidia.

Murdock BJ, Shreiner AB, McDonald RA, Osterholzer JJ, White ES, Toews GB, Huffnagle GB.

Infect Immun. 2011 Jan;79(1):125-35. doi: 10.1128/IAI.00508-10. Epub 2010 Nov 1.

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