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Items: 1 to 50 of 63

1.

Integron-Derived Aminoglycoside-Sensing Riboswitches Control Aminoglycoside Acetyltransferase Resistance Gene Expression.

Wang S, He W, Sun W, Zhang J, Chang Y, Chen D, Murchie AIH.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00236-19. doi: 10.1128/AAC.00236-19. Print 2019 Jun.

PMID:
30936094
2.

Osmium tetroxide as a probe of RNA structure.

Zhang J, Li D, Zhang J, Chen D, Murchie AI.

RNA. 2017 Apr;23(4):483-492. doi: 10.1261/rna.057539.116. Epub 2017 Jan 23.

3.

Substrate recognition and modification by the nosiheptide resistance methyltransferase.

Yin S, Jiang H, Chen D, Murchie AI.

PLoS One. 2015 Apr 24;10(4):e0122972. doi: 10.1371/journal.pone.0122972. eCollection 2015.

4.

An aminoglycoside sensing riboswitch controls the expression of aminoglycoside resistance acetyltransferase and adenyltransferases.

Chen D, Murchie AI.

Biochim Biophys Acta. 2014 Oct;1839(10):951-8. doi: 10.1016/j.bbagrm.2014.02.019. Epub 2014 Mar 12.

PMID:
24631585
5.

Riboswitch control of induction of aminoglycoside resistance acetyl and adenyl-transferases.

He W, Zhang X, Zhang J, Jia X, Zhang J, Sun W, Jiang H, Chen D, Murchie AI.

RNA Biol. 2013 Aug;10(8):1266-73. doi: 10.4161/rna.25757. Epub 2013 Jul 15.

6.

Riboswitch regulation of aminoglycoside resistance acetyl and adenyl transferases.

Jia X, Zhang J, Sun W, He W, Jiang H, Chen D, Murchie AI.

Cell. 2013 Jun 20;153(7):1419-20. doi: 10.1016/j.cell.2013.05.050. No abstract available.

7.

Riboswitch control of aminoglycoside antibiotic resistance.

Jia X, Zhang J, Sun W, He W, Jiang H, Chen D, Murchie AI.

Cell. 2013 Jan 17;152(1-2):68-81. doi: 10.1016/j.cell.2012.12.019.

9.

The global transcriptional response of fission yeast to hydrogen sulfide.

Jia X, He W, Murchie AI, Chen D.

PLoS One. 2011;6(12):e28275. doi: 10.1371/journal.pone.0028275. Epub 2011 Dec 2.

10.

Identification and characterization of the mitochondrial RNA polymerase and transcription factor in the fission yeast Schizosaccharomyces pombe.

Jiang H, Sun W, Wang Z, Zhang J, Chen D, Murchie AI.

Nucleic Acids Res. 2011 Jul;39(12):5119-30. doi: 10.1093/nar/gkr103. Epub 2011 Feb 26.

11.

A novel function of the mitochondrial transcription factor Mtf1 in fission yeast; Mtf1 regulates the nuclear transcription of srk1.

Sun W, Wang Z, Jiang H, Zhang J, Bähler J, Chen D, Murchie AI.

Nucleic Acids Res. 2011 Apr;39(7):2690-700. doi: 10.1093/nar/gkq1179. Epub 2010 Dec 7.

12.

Crystal structure of the nosiheptide-resistance methyltransferase of Streptomyces actuosus.

Yang H, Wang Z, Shen Y, Wang P, Jia X, Zhao L, Zhou P, Gong R, Li Z, Yang Y, Chen D, Murchie AI, Xu Y.

Biochemistry. 2010 Aug 3;49(30):6440-50. doi: 10.1021/bi1005915.

PMID:
20550164
13.

Nucleic acid structure and recognition.

Duckett DR, Murchie AI, Clegg RM, Bassi GS, Giraud-Panis MJ, Lilley DM.

Biophys Chem. 1997 Oct;68(1-3):53-62.

PMID:
17029905
14.

Structure-based drug design targeting an inactive RNA conformation: exploiting the flexibility of HIV-1 TAR RNA.

Murchie AI, Davis B, Isel C, Afshar M, Drysdale MJ, Bower J, Potter AJ, Starkey ID, Swarbrick TM, Mirza S, Prescott CD, Vaglio P, Aboul-ela F, Karn J.

J Mol Biol. 2004 Feb 20;336(3):625-38.

PMID:
15095977
15.

Rational design of inhibitors of HIV-1 TAR RNA through the stabilisation of electrostatic "hot spots".

Davis B, Afshar M, Varani G, Murchie AI, Karn J, Lentzen G, Drysdale M, Bower J, Potter AJ, Starkey ID, Swarbrick T, Aboul-ela F.

J Mol Biol. 2004 Feb 13;336(2):343-56.

PMID:
14757049
16.

Structural basis for contrasting activities of ribosome binding thiazole antibiotics.

Lentzen G, Klinck R, Matassova N, Aboul-ela F, Murchie AI.

Chem Biol. 2003 Aug;10(8):769-78.

PMID:
12954336
17.

RNA as a drug target.

Drysdale MJ, Lentzen G, Matassova N, Murchie AI, Aboul-Ela F, Afshar M.

Prog Med Chem. 2002;39:73-119. Review.

PMID:
12536671
18.

The bacterial ribosome, a promising focus for structure-based drug design.

Knowles DJ, Foloppe N, Matassova NB, Murchie AI.

Curr Opin Pharmacol. 2002 Oct;2(5):501-6. Review.

PMID:
12324250
19.

RNA folding and misfolding of the hammerhead ribozyme.

Bassi GS, Møllegaard NE, Murchie AI, Lilley DM.

Biochemistry. 1999 Mar 16;38(11):3345-54.

PMID:
10079078
20.

Folding of the four-way RNA junction of the hairpin ribozyme.

Walter F, Murchie AI, Lilley DM.

Biochemistry. 1998 Dec 15;37(50):17629-36.

PMID:
9860879
21.

Structure and activity of the hairpin ribozyme in its natural junction conformation: effect of metal ions.

Walter F, Murchie AI, Thomson JB, Lilley DM.

Biochemistry. 1998 Oct 6;37(40):14195-203.

PMID:
9760257
22.

Folding of the hairpin ribozyme in its natural conformation achieves close physical proximity of the loops.

Murchie AI, Thomson JB, Walter F, Lilley DM.

Mol Cell. 1998 May;1(6):873-81.

23.
24.

Ion-induced folding of the hammerhead ribozyme: a fluorescence resonance energy transfer study.

Bassi GS, Murchie AI, Walter F, Clegg RM, Lilley DM.

EMBO J. 1997 Dec 15;16(24):7481-9.

25.

Exchange between stacking conformers in a four-Way DNA junction.

Grainger RJ, Murchie AI, Lilley DM.

Biochemistry. 1998 Jan 6;37(1):23-32.

PMID:
9425022
26.

Severe helical distortion of the U1A mRNA 3' untranslated region induced by the U1A protein binding site.

Grainger RJ, Murchie AI, Lilley DM.

Biochem Soc Trans. 1997 Nov;25(4):S641. No abstract available.

PMID:
9450069
27.

The crystal structure of a parallel-stranded guanine tetraplex at 0.95 A resolution.

Phillips K, Dauter Z, Murchie AI, Lilley DM, Luisi B.

J Mol Biol. 1997 Oct 17;273(1):171-82.

PMID:
9367755
28.

Severe axial bending of RNA induced by the U1A binding element present in the 3' untranslated region of the U1A mRNA.

Grainger RJ, Murchie AI, Norman DG, Lilley DM.

J Mol Biol. 1997 Oct 17;273(1):84-92.

PMID:
9367748
29.

Global structure of three-way DNA junctions with and without additional unpaired bases: a fluorescence resonance energy transfer analysis.

Stühmeier F, Welch JB, Murchie AI, Lilley DM, Clegg RM.

Biochemistry. 1997 Nov 4;36(44):13530-8.

PMID:
9354621
31.

Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.

Duckett DR, Drummond JT, Murchie AI, Reardon JT, Sancar A, Lilley DM, Modrich P.

Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6443-7.

32.

The global folding of four-way helical junctions in RNA, including that in U1 snRNA.

Duckett DR, Murchie AI, Lilley DM.

Cell. 1995 Dec 15;83(6):1027-36.

33.

Structure of the four-way DNA junction and its interaction with proteins.

Duckett DR, Murchie AI, Giraud-Panis MJ, Pöhler JR, Lilley DM.

Philos Trans R Soc Lond B Biol Sci. 1995 Jan 30;347(1319):27-36. Review.

PMID:
7746850
34.

Ionic interactions and the global conformations of the hammerhead ribozyme.

Bassi GS, Møllegaard NE, Murchie AI, von Kitzing E, Lilley DM.

Nat Struct Biol. 1995 Jan;2(1):45-55.

PMID:
7719853
35.

Kinking of DNA and RNA helices by bulged nucleotides observed by fluorescence resonance energy transfer.

Gohlke C, Murchie AI, Lilley DM, Clegg RM.

Proc Natl Acad Sci U S A. 1994 Nov 22;91(24):11660-4.

36.
37.

The high-resolution crystal structure of a parallel-stranded guanine tetraplex.

Laughlan G, Murchie AI, Norman DG, Moore MH, Moody PC, Lilley DM, Luisi B.

Science. 1994 Jul 22;265(5171):520-4.

PMID:
8036494
38.

Uranyl photoprobing of a four-way DNA junction: evidence for specific metal ion binding.

Møllegaard NE, Murchie AI, Lilley DM, Nielsen PE.

EMBO J. 1994 Apr 1;13(7):1508-13.

39.

Tetraplex folding of telomere sequences and the inclusion of adenine bases.

Murchie AI, Lilley DM.

EMBO J. 1994 Feb 15;13(4):993-1001.

40.

Mutational analysis of the DNA binding domain A of chromosomal protein HMG1.

Falciola L, Murchie AI, Lilley DM, Bianchi M.

Nucleic Acids Res. 1994 Feb 11;22(3):285-92.

42.

T4 endonuclease VII cleaves DNA containing a cisplatin adduct.

Murchie AI, Lilley DM.

J Mol Biol. 1993 Sep 5;233(1):77-85.

PMID:
8377195
43.

Observing the helical geometry of double-stranded DNA in solution by fluorescence resonance energy transfer.

Clegg RM, Murchie AI, Zechel A, Lilley DM.

Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2994-8.

44.

The four-way DNA junction: a fluorescence resonance energy transfer study.

Clegg RM, Murchie AI, Lilley DM.

Braz J Med Biol Res. 1993 Apr;26(4):405-16.

PMID:
8298513
45.

The structure of DNA junctions and their interaction with enzymes.

Duckett DR, Murchie AI, Bhattacharyya A, Clegg RM, Diekmann S, von Kitzing E, Lilley DM.

Eur J Biochem. 1993 Jan 15;211(1-2):285-95. Review. No abstract available.

46.

Nuclear magnetic resonance study of a deoxyoligonucleotide duplex containing a three base bulge.

Aboul-ela F, Murchie AI, Homans SW, Lilley DM.

J Mol Biol. 1993 Jan 5;229(1):173-88.

PMID:
8380616
47.

NMR study of parallel-stranded tetraplex formation by the hexadeoxynucleotide d(TG4T).

Aboul-ela F, Murchie AI, Lilley DM.

Nature. 1992 Nov 19;360(6401):280-2.

PMID:
1436110
48.

Fluorescence resonance energy transfer analysis of the structure of the four-way DNA junction.

Clegg RM, Murchie AI, Zechel A, Carlberg C, Diekmann S, Lilley DM.

Biochemistry. 1992 May 26;31(20):4846-56.

PMID:
1591245
49.

Helix opening transitions in supercoiled DNA.

Murchie AI, Bowater R, Aboul-ela F, Lilley DM.

Biochim Biophys Acta. 1992 May 7;1131(1):1-15. Review. No abstract available.

PMID:
1581350
50.

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