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Items: 2

1.

Phenytoin metabolism by human cytochrome P450: involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation.

Cuttle L, Munns AJ, Hogg NA, Scott JR, Hooper WD, Dickinson RG, Gillam EM.

Drug Metab Dispos. 2000 Aug;28(8):945-50.

PMID:
10901705
2.

Bioactivation of phenytoin by human cytochrome P450: characterization of the mechanism and targets of covalent adduct formation.

Munns AJ, De Voss JJ, Hooper WD, Dickinson RG, Gillam EM.

Chem Res Toxicol. 1997 Sep;10(9):1049-58.

PMID:
9305589

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