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Items: 1 to 50 of 130

1.

Mechanosensing tensile solid stresses.

Munn LL, Nia HT.

Proc Natl Acad Sci U S A. 2019 Oct 16. pii: 201916115. doi: 10.1073/pnas.1916115116. [Epub ahead of print] No abstract available.

PMID:
31619566
2.

Vascular regulation of antitumor immunity.

Munn LL, Jain RK.

Science. 2019 Aug 9;365(6453):544-545. doi: 10.1126/science.aaw7875. No abstract available.

PMID:
31395771
3.

The effects of valve leaflet mechanics on lymphatic pumping assessed using numerical simulations.

Li H, Mei Y, Maimon N, Padera TP, Baish JW, Munn LL.

Sci Rep. 2019 Jul 23;9(1):10649. doi: 10.1038/s41598-019-46669-9.

4.

The cancer cell glycocalyx proteoglycan glypican-1 mediates interstitial flow mechanotransduction to enhance cell migration and metastasis.

Moran H, Cancel LM, Mayer MA, Qazi H, Munn LL, Tarbell JM.

Biorheology. 2019 Jun 25. doi: 10.3233/BIR-180203. [Epub ahead of print]

PMID:
31256115
5.

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium.

Seano G, Nia HT, Emblem KE, Datta M, Ren J, Krishnan S, Kloepper J, Pinho MC, Ho WW, Ghosh M, Askoxylakis V, Ferraro GB, Riedemann L, Gerstner ER, Batchelor TT, Wen PY, Lin NU, Grodzinsky AJ, Fukumura D, Huang P, Baish JW, Padera TP, Munn LL, Jain RK.

Nat Biomed Eng. 2019 Mar;3(3):230-245. doi: 10.1038/s41551-018-0334-7. Epub 2019 Jan 7.

6.

Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies.

Voutouri C, Kirkpatrick ND, Chung E, Mpekris F, Baish JW, Munn LL, Fukumura D, Stylianopoulos T, Jain RK.

Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2662-2671. doi: 10.1073/pnas.1818322116. Epub 2019 Jan 30.

7.

Mapping Physical Tumor Microenvironment and Drug Delivery.

Nia HT, Munn LL, Jain RK.

Clin Cancer Res. 2019 Apr 1;25(7):2024-2026. doi: 10.1158/1078-0432.CCR-18-3724. Epub 2019 Jan 10.

PMID:
30630829
8.

Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW.

Angiogenesis. 2018 Aug;21(3):425-532. doi: 10.1007/s10456-018-9613-x. Review.

9.

Quantifying solid stress and elastic energy from excised or in situ tumors.

Nia HT, Datta M, Seano G, Huang P, Munn LL, Jain RK.

Nat Protoc. 2018 May;13(5):1091-1105. doi: 10.1038/nprot.2018.020. Epub 2018 Apr 19.

10.

Reengineering the Physical Microenvironment of Tumors to Improve Drug Delivery and Efficacy: From Mathematical Modeling to Bench to Bedside.

Stylianopoulos T, Munn LL, Jain RK.

Trends Cancer. 2018 Apr;4(4):292-319. doi: 10.1016/j.trecan.2018.02.005. Epub 2018 Mar 13. Review.

11.

Reengineering the Tumor Vasculature: Improving Drug Delivery and Efficacy.

Stylianopoulos T, Munn LL, Jain RK.

Trends Cancer. 2018 Apr;4(4):258-259. doi: 10.1016/j.trecan.2018.02.010. Epub 2018 Mar 17. Review.

12.

Lymphatic function measurements influenced by contrast agent volume and body position.

Bouta EM, Blatter C, Ruggieri TA, Meijer EF, Munn LL, Vakoc BJ, Padera TP.

JCI Insight. 2018 Jan 25;3(2). pii: 96591. doi: 10.1172/jci.insight.96591. eCollection 2018 Jan 25.

13.

SLPI: a new target for stopping metastasis.

Munn LL, Garkavtsev I.

Aging (Albany NY). 2018 Jan 20;10(1):13-14. doi: 10.18632/aging.101372. No abstract available.

14.

Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction.

Jones D, Meijer EFJ, Blatter C, Liao S, Pereira ER, Bouta EM, Jung K, Chin SM, Huang P, Munn LL, Vakoc BJ, Otto M, Padera TP.

Sci Transl Med. 2018 Jan 17;10(424). pii: eaam7964. doi: 10.1126/scitranslmed.aam7964.

15.

Vascular beds maintain pancreatic tumour explants for ex vivo drug screening.

Bazou D, Maimon N, Gruionu G, Grahovac J, Seano G, Liu H, Evans CL, Munn LL.

J Tissue Eng Regen Med. 2018 Jan;12(1):e318-e322. doi: 10.1002/term.2481. Epub 2017 Sep 12.

16.

Stress granule-associated protein G3BP2 regulates breast tumor initiation.

Gupta N, Badeaux M, Liu Y, Naxerova K, Sgroi D, Munn LL, Jain RK, Garkavtsev I.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1033-1038. doi: 10.1073/pnas.1525387114. Epub 2017 Jan 17.

17.

Cancer and inflammation.

Munn LL.

Wiley Interdiscip Rev Syst Biol Med. 2017 Mar;9(2). doi: 10.1002/wsbm.1370. Epub 2016 Dec 12. Review.

18.

Synchronization and Random Triggering of Lymphatic Vessel Contractions.

Baish JW, Kunert C, Padera TP, Munn LL.

PLoS Comput Biol. 2016 Dec 9;12(12):e1005231. doi: 10.1371/journal.pcbi.1005231. eCollection 2016 Dec.

19.

Self-assembly of vascularized tissue to support tumor explants in vitro.

Bazou D, Maimon N, Gruionu G, Munn LL.

Integr Biol (Camb). 2016 Dec 5;8(12):1301-1311.

20.

Flow-induced HDAC1 phosphorylation and nuclear export in angiogenic sprouting.

Bazou D, Ng MR, Song JW, Chin SM, Maimon N, Munn LL.

Sci Rep. 2016 Sep 27;6:34046. doi: 10.1038/srep34046.

21.

Heparan sulfate proteoglycans mediate renal carcinoma metastasis.

Qazi H, Shi ZD, Song JW, Cancel LM, Huang P, Zeng Y, Roberge S, Munn LL, Tarbell JM.

Int J Cancer. 2016 Dec 15;139(12):2791-2801. doi: 10.1002/ijc.30397. Epub 2016 Sep 9.

22.

Implantable tissue isolation chambers for analyzing tumor dynamics in vivo.

Gruionu G, Bazou D, Maimon N, Onita-Lenco M, Gruionu LG, Huang P, Munn LL.

Lab Chip. 2016 May 21;16(10):1840-51. doi: 10.1039/c6lc00237d. Epub 2016 Apr 29.

23.

Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival.

Kloepper J, Riedemann L, Amoozgar Z, Seano G, Susek K, Yu V, Dalvie N, Amelung RL, Datta M, Song JW, Askoxylakis V, Taylor JW, Lu-Emerson C, Batista A, Kirkpatrick ND, Jung K, Snuderl M, Muzikansky A, Stubenrauch KG, Krieter O, Wakimoto H, Xu L, Munn LL, Duda DG, Fukumura D, Batchelor TT, Jain RK.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4476-81. doi: 10.1073/pnas.1525360113. Epub 2016 Apr 4.

24.

The Lymphatic System in Disease Processes and Cancer Progression.

Padera TP, Meijer EF, Munn LL.

Annu Rev Biomed Eng. 2016 Jul 11;18:125-58. doi: 10.1146/annurev-bioeng-112315-031200. Epub 2016 Feb 5. Review.

25.

Reply to Davis: Nitric oxide regulates lymphatic contractions.

Kunert C, Baish JW, Liao S, Padera TP, Munn LL.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):E106. doi: 10.1073/pnas.1522233113. Epub 2015 Dec 30. No abstract available.

26.

Solid stress and elastic energy as measures of tumour mechanopathology.

Nia HT, Liu H, Seano G, Datta M, Jones D, Rahbari N, Incio J, Chauhan VP, Jung K, Martin JD, Askoxylakis V, Padera TP, Fukumura D, Boucher Y, Hornicek FJ, Grodzinsky AJ, Baish JW, Munn LL, Jain RK.

Nat Biomed Eng. 2016;1. pii: 0004. doi: 10.1038/s41551-016-0004. Epub 2016 Nov 28.

27.

Mechanobiological oscillators control lymph flow.

Kunert C, Baish JW, Liao S, Padera TP, Munn LL.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):10938-43. doi: 10.1073/pnas.1508330112. Epub 2015 Aug 17.

28.

Mechanobiology of lymphatic contractions.

Munn LL.

Semin Cell Dev Biol. 2015 Feb;38:67-74. doi: 10.1016/j.semcdb.2015.01.010. Epub 2015 Jan 28. Review.

PMID:
25636584
29.

Microfluidic model of angiogenic sprouting.

Song JW, Bazou D, Munn LL.

Methods Mol Biol. 2015;1214:243-54. doi: 10.1007/978-1-4939-1462-3_15.

PMID:
25468609
30.

Compression of pancreatic tumor blood vessels by hyaluronan is caused by solid stress and not interstitial fluid pressure.

Chauhan VP, Boucher Y, Ferrone CR, Roberge S, Martin JD, Stylianopoulos T, Bardeesy N, DePinho RA, Padera TP, Munn LL, Jain RK.

Cancer Cell. 2014 Jul 14;26(1):14-5. doi: 10.1016/j.ccr.2014.06.003. No abstract available.

31.

Imaging the lymphatic system.

Munn LL, Padera TP.

Microvasc Res. 2014 Nov;96:55-63. doi: 10.1016/j.mvr.2014.06.006. Epub 2014 Jun 21. Review.

32.

Dynamics of tissue topology during cancer invasion and metastasis.

Munn LL.

Phys Biol. 2013 Dec;10(6):065003. doi: 10.1088/1478-3975/10/6/065003. Epub 2013 Dec 4.

33.

Cancer cell glycocalyx mediates mechanotransduction and flow-regulated invasion.

Qazi H, Palomino R, Shi ZD, Munn LL, Tarbell JM.

Integr Biol (Camb). 2013 Nov;5(11):1334-43. doi: 10.1039/c3ib40057c. Epub 2013 Sep 30.

34.

Measuring interstitial diffusion, convection, and binding parameters in mouse tumors.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2013 Jul 1;2013(7):678-80. doi: 10.1101/pdb.prot075721.

PMID:
23818670
35.

Measuring interstitial pH and pO2 in mouse tumors.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2013 Jul 1;2013(7):675-7. doi: 10.1101/pdb.prot075713.

PMID:
23818669
36.

Measuring leukocyte-endothelial interactions in mice.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2013 Jun 1;2013(6):561-3. doi: 10.1101/pdb.prot075085.

PMID:
23734020
37.

Can we identify predictive biomarkers for antiangiogenic therapy of cancer using mathematical modeling?

Duda DG, Munn LL, Jain RK.

J Natl Cancer Inst. 2013 Jun 5;105(11):762-5. doi: 10.1093/jnci/djt114. Epub 2013 May 13. No abstract available.

38.

Measuring vascular permeability in mice.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2013 May 1;2013(5):444-6. doi: 10.1101/pdb.prot074344.

PMID:
23637370
39.

Measuring angiogenesis and hemodynamics in mice.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2013 Apr 1;2013(4):354-8. doi: 10.1101/pdb.prot073916.

PMID:
23547161
40.

Lung window preparation in mice.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2013 Jan 1;2013(1). pii: pdb.prot072678. doi: 10.1101/pdb.prot072678.

PMID:
23282642
41.

Liver tumor preparation in mice.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2012 Dec 1;2012(12). pii: pdb.prot072371. doi: 10.1101/pdb.prot072371.

PMID:
23209146
42.

Pancreatic tumor preparation in mice.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2012 Dec 1;2012(12). pii: pdb.prot072363. doi: 10.1101/pdb.prot072363.

PMID:
23209145
43.

Lymphatic vessels in health and disease.

Kesler CT, Liao S, Munn LL, Padera TP.

Wiley Interdiscip Rev Syst Biol Med. 2013 Jan-Feb;5(1):111-24. doi: 10.1002/wsbm.1201. Epub 2012 Dec 3. Review.

44.

Lymphangiography of the mouse ear.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2012 Nov 1;2012(11):1179-80. doi: 10.1101/pdb.prot072116.

PMID:
23118365
45.

Lymphangiography of the mouse tail.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2012 Nov 1;2012(11):1177-8. doi: 10.1101/pdb.prot072108.

PMID:
23118364
46.

RhoA mediates flow-induced endothelial sprouting in a 3-D tissue analogue of angiogenesis.

Song JW, Daubriac J, Tse JM, Bazou D, Munn LL.

Lab Chip. 2012 Dec 7;12(23):5000-6. doi: 10.1039/c2lc40389g.

47.

Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy.

Huang Y, Yuan J, Righi E, Kamoun WS, Ancukiewicz M, Nezivar J, Santosuosso M, Martin JD, Martin MR, Vianello F, Leblanc P, Munn LL, Huang P, Duda DG, Fukumura D, Jain RK, Poznansky MC.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17561-6. doi: 10.1073/pnas.1215397109. Epub 2012 Oct 8.

48.

Mammary fat pad tumor preparation in mice.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2012 Oct 1;2012(10):1115-6. doi: 10.1101/pdb.prot071514.

PMID:
23028076
49.

Mammary fat pad chamber preparation in mice.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2012 Oct 1;2012(10):1113-4. doi: 10.1101/pdb.prot071506.

PMID:
23028075
50.

Corneal pocket assay in rabbits.

Jain RK, Munn LL, Fukumura D.

Cold Spring Harb Protoc. 2012 Sep 1;2012(9):1017-8. doi: 10.1101/pdb.prot070052.

PMID:
22949714

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