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Assessment of the Efficacy of Therapies Following Venetoclax Discontinuation in CLL Reveals BTK inhibition as an Effective Strategy.

Mato AR, Roeker LE, Jacobs R, Hill BT, Lamanna N, Brander D, Shadman M, Ujjani CS, Sarraf Yazdy M, Perini GF, Pinilla-Ibarz JA, Barrientos J, Skarbnik AP, Torka P, Pu JJ, Pagel JM, Gohil S, Fakhri B, Choi M, Coombs CC, Rhodes J, Barr PM, Portell CA, Parry H, Garcia CA, Whitaker KJ, Winter AM, Sitlinger A, Khajavian S, Grajales-Cruz AF, Isaac KM, Shah P, Akhtar OS, Pocock R, Lam K, Voorhees TJ, Schuster SJ, Rodgers TD, Fox CP, Martinez-Calle N, Munir T, Bhavsar EB, Bailey N, Lee JC, Weissbrot HB, Nabhan C, Goodfriend JM, King AC, Zelenetz AD, Dorsey C, Bigelow K, Cheson BD, Allan JN, Eyre TA.

Clin Cancer Res. 2020 Mar 20. pii: clincanres.3815.2019. doi: 10.1158/1078-0432.CCR-19-3815. [Epub ahead of print]


Presentation clinical, haematological and immunophenotypic features of 1081 patients with GPI-deficient (paroxysmal nocturnal haemoglobinuria) cells detected by flow cytometry.

Richards SJ, Dickinson AJ, Cullen MJ, Griffin M, Munir T, McKinley C, Mitchell LD, Newton DJ, Arnold L, Hill A, Hillmen P.

Br J Haematol. 2020 Feb 27. doi: 10.1111/bjh.16427. [Epub ahead of print]


Prevalence of latent tuberculosis infection in healthcare workers in tertiary care hospitals of Pakistan.

Sadaf R, Munir T, Farrukh S, Abbasi S.

Pak J Med Sci. 2020 Jan-Feb;36(2):198-202. doi: 10.12669/pjms.36.2.936.


The Synergistic Use of IL-15 and IL-21 for the Generation of NK Cells From CD3/CD19-Depleted Grafts Improves Their ex vivo Expansion and Cytotoxic Potential Against Neuroblastoma: Perspective for Optimized Immunotherapy Post Haploidentical Stem Cell Transplantation.

Heinze A, Grebe B, Bremm M, Huenecke S, Munir TA, Graafen L, Frueh JT, Merker M, Rettinger E, Soerensen J, Klingebiel T, Bader P, Ullrich E, Cappel C.

Front Immunol. 2019 Dec 3;10:2816. doi: 10.3389/fimmu.2019.02816. eCollection 2019.


Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL.

Kwok M, Oldreive C, Rawstron AC, Goel A, Papatzikas G, Jones RE, Drennan S, Agathanggelou A, Sharma-Oates A, Evans P, Smith E, Dalal S, Mao J, Hollows R, Gordon N, Hamada M, Davies NJ, Parry H, Beggs AD, Munir T, Moreton P, Paneesha S, Pratt G, Taylor AMR, Forconi F, Baird DM, Cazier JB, Moss P, Hillmen P, Stankovic T.

Blood. 2020 Feb 6;135(6):411-428. doi: 10.1182/blood.2019001262.


Role of cotton sticks biochar in immobilization of nickel under induced toxicity condition and growth indices of Trigonella corniculata L.

Younis U, Danish S, Malik SA, Ahmed N, Munir TM, Rasheed MK.

Environ Sci Pollut Res Int. 2020 Jan;27(2):1752-1761. doi: 10.1007/s11356-019-06466-3. Epub 2019 Nov 22.


Alleviation of chromium toxicity in maize by Fe fortification and chromium tolerant ACC deaminase producing plant growth promoting rhizobacteria.

Danish S, Kiran S, Fahad S, Ahmad N, Ali MA, Tahir FA, Rasheed MK, Shahzad K, Li X, Wang D, Mubeen M, Abbas S, Munir TM, Hashmi MZ, Adnan M, Saeed B, Saud S, Khan MN, Ullah A, Nasim W.

Ecotoxicol Environ Saf. 2019 Dec 15;185:109706. doi: 10.1016/j.ecoenv.2019.109706. Epub 2019 Sep 24.


Final analysis from RESONATE: Up to six years of follow-up on ibrutinib in patients with previously treated chronic lymphocytic leukemia or small lymphocytic lymphoma.

Munir T, Brown JR, O'Brien S, Barrientos JC, Barr PM, Reddy NM, Coutre S, Tam CS, Mulligan SP, Jaeger U, Kipps TJ, Moreno C, Montillo M, Burger JA, Byrd JC, Hillmen P, Dai S, Szoke A, Dean JP, Woyach JA.

Am J Hematol. 2019 Dec;94(12):1353-1363. doi: 10.1002/ajh.25638. Epub 2019 Oct 13.


Ibrutinib Plus Venetoclax in Relapsed/Refractory Chronic Lymphocytic Leukemia: The CLARITY Study.

Hillmen P, Rawstron AC, Brock K, Muñoz-Vicente S, Yates FJ, Bishop R, Boucher R, MacDonald D, Fegan C, McCaig A, Schuh A, Pettitt A, Gribben JG, Patten PEM, Devereux S, Bloor A, Fox CP, Forconi F, Munir T.

J Clin Oncol. 2019 Oct 20;37(30):2722-2729. doi: 10.1200/JCO.19.00894. Epub 2019 Jul 11.


Ibrutinib induces chromatin reorganisation of chronic lymphocytic leukaemia cells.

Holmes KB, Sadreev II, Rawstron AC, Munir T, Westhead DR, Hillmen P, Lefevre PF.

Oncogenesis. 2019 May 10;8(5):32. doi: 10.1038/s41389-019-0142-2.


A cross-sectional study of methicillin-resistant Staphylococcus aureus at the equine-human interface.

Waqar N, Amin Q, Munir T, Ikram MS, Shahzad N, Mirza A, Ali A, Arshad MI.

Trop Anim Health Prod. 2019 Sep;51(7):1927-1933. doi: 10.1007/s11250-019-01888-0. Epub 2019 Apr 10.


Clinical and morphological predictors of outcome in older aplastic anemia patients treated with eltrombopag.

Fattizzo B, Kulasekararaj AG, Hill A, Benson-Quarm N, Griffin M, Munir T, Arnold L, Riley K, Ireland R, De Lavallade H, Potter V, Consonni D, Hillmen P, Mufti GJ, Barcellini W, Marsh JCW.

Haematologica. 2019 Nov;104(11):e494-e496. doi: 10.3324/haematol.2019.216374. Epub 2019 Mar 19. No abstract available.


Efficacy of venetoclax monotherapy in patients with relapsed chronic lymphocytic leukaemia in the post-BCR inhibitor setting: a UK wide analysis.

Eyre TA, Kirkwood AA, Gohill S, Follows G, Walewska R, Walter H, Cross M, Forconi F, Shah N, Chasty R, Hart A, Broom A, Marr H, Patten PEM, Dann A, Arumainathan A, Munir T, Shankara P, Bloor A, Johnston R, Orchard K, Schuh AH, Fox CP; the UK CLL Forum.

Br J Haematol. 2019 May;185(4):656-669. doi: 10.1111/bjh.15802. Epub 2019 Feb 15.


Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration.

Tsarouchas TM, Wehner D, Cavone L, Munir T, Keatinge M, Lambertus M, Underhill A, Barrett T, Kassapis E, Ogryzko N, Feng Y, van Ham TJ, Becker T, Becker CG.

Nat Commun. 2018 Nov 7;9(1):4670. doi: 10.1038/s41467-018-07036-w.


Mango Fruit Yield and Critical Quality Parameters Respond to Foliar and Soil Applications of Zinc and Boron.

Ahmad I, Bibi F, Ullah H, Munir TM.

Plants (Basel). 2018 Nov 3;7(4). pii: E97. doi: 10.3390/plants7040097.


Phosphorous recovery through struvite crystallization: Challenges for future design.

Li B, Boiarkina I, Yu W, Huang HM, Munir T, Wang GQ, Young BR.

Sci Total Environ. 2019 Jan 15;648:1244-1256. doi: 10.1016/j.scitotenv.2018.07.166. Epub 2018 Aug 5. Review.


Significant hemolysis is not required for thrombosis in paroxysmal nocturnal hemoglobinuria.

Griffin M, Hillmen P, Munir T, Richards S, Arnold L, Riley K, Hill A.

Haematologica. 2019 Mar;104(3):e94-e96. doi: 10.3324/haematol.2018.198846. Epub 2018 Oct 4. No abstract available.


Venetoclax for Patients With Chronic Lymphocytic Leukemia With 17p Deletion: Results From the Full Population of a Phase II Pivotal Trial.

Stilgenbauer S, Eichhorst B, Schetelig J, Hillmen P, Seymour JF, Coutre S, Jurczak W, Mulligan SP, Schuh A, Assouline S, Wendtner CM, Roberts AW, Davids MS, Bloehdorn J, Munir T, Böttcher S, Zhou L, Salem AH, Desai M, Chyla B, Arzt J, Kim SY, Verdugo M, Gordon G, Hallek M, Wierda WG.

J Clin Oncol. 2018 Jul 1;36(19):1973-1980. doi: 10.1200/JCO.2017.76.6840. Epub 2018 May 1. Erratum in: J Clin Oncol. 2019 Sep 1;37(25):2299.


Phenotypic Identification, Frequency Distribution and Antibiogram of Carbapenemase Producing Enterobacteriaceae in Clinical Isolates.

Ansari M, Munir T, Saad N.

J Coll Physicians Surg Pak. 2018 Apr;28(4):274-278. doi: 10.29271/jcpsp.2018.04.274.


Concurrent treatment of aplastic anemia/paroxysmal nocturnal hemoglobinuria syndrome with immunosuppressive therapy and eculizumab: a UK experience.

Griffin M, Kulasekararaj A, Gandhi S, Munir T, Richards S, Arnold L, Benson-Quarm N, Copeland N, Duggins I, Riley K, Hillmen P, Marsh J, Hill A.

Haematologica. 2018 Aug;103(8):e345-e347. doi: 10.3324/haematol.2017.183046. Epub 2018 Mar 15. No abstract available.


Draft Genome Sequence of a Salmonella enterica Serovar Typhi Strain Resistant to Fourth-Generation Cephalosporin and Fluoroquinolone Antibiotics.

Gul D, Potter RF, Riaz H, Ashraf ST, Wallace MA, Munir T, Ali A, Burnham CA, Dantas G, Andleeb S.

Genome Announc. 2017 Oct 19;5(42). pii: e00850-17. doi: 10.1128/genomeA.00850-17.


Assessment of ibrutinib plus rituximab in front-line CLL (FLAIR trial): study protocol for a phase III randomised controlled trial.

Collett L, Howard DR, Munir T, McParland L, Oughton JB, Rawstron AC, Hockaday A, Dimbleby C, Phillips D, McMahon K, Hulme C, Allsup D, Bloor A, Hillmen P.

Trials. 2017 Aug 22;18(1):387. doi: 10.1186/s13063-017-2138-6.


Highly selective SYK inhibitor, GSK143, abrogates survival signals in chronic lymphocytic leukaemia.

Varghese AM, Rawstron A, Newton D, Tooze RM, Munir T, Dickson M, Doody GM, Hillmen P.

Br J Haematol. 2018 Sep;182(6):927-930. doi: 10.1111/bjh.14884. Epub 2017 Aug 2. No abstract available.


GA101 (obinutuzumab) monocLonal Antibody as Consolidation Therapy In CLL (GALACTIC) trial: study protocol for a phase II/III randomised controlled trial.

Oughton JB, Collett L, Howard DR, Hockaday A, Munir T, McMahon K, McParland L, Dimbleby C, Phillips D, Rawstron AC, Hillmen P.

Trials. 2017 Jul 26;18(1):353. doi: 10.1186/s13063-017-2107-0.


Extended follow-up and impact of high-risk prognostic factors from the phase 3 RESONATE study in patients with previously treated CLL/SLL.

Brown JR, Hillmen P, O'Brien S, Barrientos JC, Reddy NM, Coutre SE, Tam CS, Mulligan SP, Jaeger U, Barr PM, Furman RR, Kipps TJ, Cymbalista F, Thornton P, Caligaris-Cappio F, Delgado J, Montillo M, DeVos S, Moreno C, Pagel JM, Munir T, Burger JA, Chung D, Lin J, Gau L, Chang B, Cole G, Hsu E, James DF, Byrd JC.

Leukemia. 2018 Jan;32(1):83-91. doi: 10.1038/leu.2017.175. Epub 2017 Jun 8.


Results of the randomized phase IIB ARCTIC trial of low-dose rituximab in previously untreated CLL.

Howard DR, Munir T, McParland L, Rawstron AC, Milligan D, Schuh A, Hockaday A, Allsup DJ, Marshall S, Duncombe AS, O'Dwyer JL, Smith AF, Longo R, Varghese A, Hillmen P.

Leukemia. 2017 Nov;31(11):2416-2425. doi: 10.1038/leu.2017.96. Epub 2017 Mar 24.


Management of thrombosis in paroxysmal nocturnal hemoglobinuria: a clinician's guide.

Griffin M, Munir T.

Ther Adv Hematol. 2017 Mar;8(3):119-126. doi: 10.1177/2040620716681748. Epub 2016 Dec 21. Review.


Results of the randomized phase IIB ADMIRE trial of FCR with or without mitoxantrone in previously untreated CLL.

Munir T, Howard DR, McParland L, Pocock C, Rawstron AC, Hockaday A, Varghese A, Hamblin M, Bloor A, Pettitt A, Fegan C, Blundell J, Gribben JG, Phillips D, Hillmen P.

Leukemia. 2017 Oct;31(10):2085-2093. doi: 10.1038/leu.2017.65. Epub 2017 Apr 20.


Chemotherapy plus Ofatumumab at Standard or Mega dose in relapsed CLL (COSMIC) trial: study protocol for a phase II randomised controlled trial.

Howard DR, Munir T, Hockaday A, Rawstron AC, Collett L, Oughton JB, Allsup D, Bloor A, Phillips D, Hillmen P.

Trials. 2016 Sep 20;17(1):456. doi: 10.1186/s13063-016-1581-0.


Single-center Series of Bone Marrow Biopsy-Defined Large Granular Lymphocyte Leukemia: High Rates of Sustained Response to Oral Methotrexate.

Munir T, Bishton MJ, Carter I, McMillan A, O'Connor S, Sovani V, Haynes AP, Fox CP.

Clin Lymphoma Myeloma Leuk. 2016 Dec;16(12):705-712. doi: 10.1016/j.clml.2016.08.014. Epub 2016 Aug 10.


Extended Spectrum Beta Lactamase producing Cephalosporin resistant Salmonella Typhi, reported from Rawalpindi, Pakistan.

Munir T, Lodhi M, Ansari JK, Andleeb S, Ahmed M.

J Pak Med Assoc. 2016 Aug;66(8):1035-6.


ICU Pathogens: A Continuous Challenge.

Hafeez A, Munir T, Najeeb S, Rehman S, Gilani M, Ansari M, Saad N.

J Coll Physicians Surg Pak. 2016 Jul;26(7):577-80. doi: 2374.


Methicillin resistant coagulase negative staphylococcus: From colonizer to a pathogen.

Gilani M, Usman J, Latif M, Munir T, Gill MM, Anjum R, Babar N.

Pak J Pharm Sci. 2016 Jul;29(4):1117-21.


Venetoclax in relapsed or refractory chronic lymphocytic leukaemia with 17p deletion: a multicentre, open-label, phase 2 study.

Stilgenbauer S, Eichhorst B, Schetelig J, Coutre S, Seymour JF, Munir T, Puvvada SD, Wendtner CM, Roberts AW, Jurczak W, Mulligan SP, Böttcher S, Mobasher M, Zhu M, Desai M, Chyla B, Verdugo M, Enschede SH, Cerri E, Humerickhouse R, Gordon G, Hallek M, Wierda WG.

Lancet Oncol. 2016 Jun;17(6):768-778. doi: 10.1016/S1470-2045(16)30019-5. Epub 2016 May 10.


An ultra-deep sequencing strategy to detect sub-clonal TP53 mutations in presentation chronic lymphocytic leukaemia cases using multiple polymerases.

Worrillow L, Baskaran P, Care MA, Varghese A, Munir T, Evans PA, O'Connor SJ, Rawstron A, Hazelwood L, Tooze RM, Hillmen P, Newton DJ.

Oncogene. 2016 Oct 6;35(40):5328-5336. doi: 10.1038/onc.2016.73. Epub 2016 Apr 4.


Dissolved organic carbon in a constructed and natural fens in the Athabasca oil sands region, Alberta, Canada.

Khadka B, Munir TM, Strack M.

Sci Total Environ. 2016 Jul 1;557-558:579-89. doi: 10.1016/j.scitotenv.2016.03.081. Epub 2016 Mar 31.


In Vitro Efficacy of Doripenem against Pseudomonas aeruginosa and Acinetobacter baumannii by E-Test.

Gilani M, Munir T, Latif M, Rehman S, Ansari M, Hafeez A, Najeeb S, Saad N, Gilani M.

J Coll Physicians Surg Pak. 2015 Oct;25(10):726-9. doi: 10.2015/JCPSP.726729.


Early Diagnosis of Typhoid By PCR For FliC-d Gene of Salmonella Typhi in Patients Taking Antibiotics.

Munir T, Lodhi M, Ali S, Hussain Zaidi SB, Razak S.

J Coll Physicians Surg Pak. 2015 Sep;25(9):662-6. doi: 09.2015/JCPSP.662666.


Coagulase negative staphylococci - a fast emerging threat.

Latif M, Usman J, Gilani M, Munir T, Mushtaq M, Anjum R.

J Pak Med Assoc. 2015 Mar;65(3):283-6.


Chronic lymphocytic leukemia.

Munir T.

Hematology. 2015 May;20(4):245-6. doi: 10.1179/1024533215Z.000000000356. No abstract available.


Comparative Efficacy of Ceftaroline with Linezolid against Staphylococcus aureus and Methicillin Resistant Staphylococcus aureus.

Hafeez A, Munir T, Rehman S, Najeeb S, Gilani M, Latif M, Ansari M, Saad N.

J Coll Physicians Surg Pak. 2015 Apr;25(4):247-9. doi: 04.2015/JCPSP.247249.


Comparison of urine dipstick test with conventional urine culture in diagnosis of urinary tract infection.

Najeeb S, Munir T, Rehman S, Hafiz A, Gilani M, Latif M.

J Coll Physicians Surg Pak. 2015 Feb;25(2):108-10. doi: 02.2015/JCPSP.108110.


Teaching obstetrics and gynaecology to male undergraduate medical students: student's perception.

Alam K, Safdar CA, Munir TA, Ghani Z.

J Ayub Med Coll Abbottabad. 2014 Oct-Dec;26(4):539-42.


Frequency and antibiogram of vancomycin resistant enterococcus in a tertiary care hospital.

Babar N, Usman J, Munir T, Gill MM, Anjum R, Gilani M, Latif M.

J Coll Physicians Surg Pak. 2014 Jan;24(1):27-9. doi: 01.2014/JCPSP.2729.


Ogilvie's syndrome (acute colonic pseudo-obstruction) after caesarean section.

Munzar Z, Munir TA, Asad M.

J Coll Physicians Surg Pak. 2013 Apr;23(4):298-300. doi: 04.2013/JCPSP.298300.


Emergency contraception: knowledge, attitude and practices among doctors of a tertiary care hospital.

Alam K, Snover A, Sultana N, Munir TA, Shah SS.

J Ayub Med Coll Abbottabad. 2013 Jan-Jun;25(1-2):141-4.


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