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Items: 45


Qualifying X-ray and Stimulated Raman Spectromicroscopy for Mapping Cutaneous Drug Penetration.

Wanjiku B, Yamamoto K, Klossek A, Schumacher F, Pischon H, Mundhenk L, Rancan F, Judd MM, Ahmed M, Zoschke C, Kleuser B, Rühl E, Schäfer-Korting M.

Anal Chem. 2019 Jun 4;91(11):7208-7214. doi: 10.1021/acs.analchem.9b00519. Epub 2019 May 15.


Soft X-ray microscopy for probing of topical tacrolimus delivery via micelles.

Yamamoto K, Klossek A, Fuchs K, Watts B, Raabe J, Flesch R, Rancan F, Pischon H, Radbruch M, Gruber AD, Mundhenk L, Vogt A, Blume-Peytavi U, Schrade P, Bachmann S, Gurny R, Rühl E.

Eur J Pharm Biopharm. 2019 Jun;139:68-75. doi: 10.1016/j.ejpb.2019.03.006. Epub 2019 Mar 6.


Quantification and characterization of radical production in human, animal and 3D skin models during sun irradiation measured by EPR spectroscopy.

Albrecht S, Elpelt A, Kasim C, Reble C, Mundhenk L, Pischon H, Hedtrich S, Witzel C, Lademann J, Zastrow L, Beckers I, Meinke MC.

Free Radic Biol Med. 2019 Feb 1;131:299-308. doi: 10.1016/j.freeradbiomed.2018.12.022. Epub 2018 Dec 18.


Grayanotoxin I Intoxication in Pet Pigs.

Pischon H, Petrick A, Müller M, Köster N, Pietsch J, Mundhenk L.

Vet Pathol. 2018 Nov;55(6):896-899. doi: 10.1177/0300985818789482. Epub 2018 Aug 2.


An unexpected diagnosis in a cat with sudden lameness.

Erickson NA, Münzer B, Dunkel M, Mundhenk L.

J Small Anim Pract. 2018 Jul 4. doi: 10.1111/jsap.12899. [Epub ahead of print] No abstract available.


Visualizing Oxidative Cellular Stress Induced by Nanoparticles in the Subcytotoxic Range Using Fluorescence Lifetime Imaging.

Balke J, Volz P, Neumann F, Brodwolf R, Wolf A, Pischon H, Radbruch M, Mundhenk L, Gruber AD, Ma N, Alexiev U.

Small. 2018 Jun;14(23):e1800310. doi: 10.1002/smll.201800310. Epub 2018 May 4.


Soluble mucus component CLCA1 modulates expression of leukotactic cytokines and BPIFA1 in murine alveolar macrophages but not in bone marrow-derived macrophages.

Erickson NA, Dietert K, Enders J, Glauben R, Nouailles G, Gruber AD, Mundhenk L.

Histochem Cell Biol. 2018 Jun;149(6):619-633. doi: 10.1007/s00418-018-1664-y. Epub 2018 Apr 2.


Crosstalk between core-multishell nanocarriers for cutaneous drug delivery and antigen-presenting cells of the skin.

Edlich A, Volz P, Brodwolf R, Unbehauen M, Mundhenk L, Gruber AD, Hedtrich S, Haag R, Alexiev U, Kleuser B.

Biomaterials. 2018 Apr;162:60-70. doi: 10.1016/j.biomaterials.2018.01.058. Epub 2018 Feb 3.


Fatal Neurotoxicosis in Dogs Associated with Tychoplanktic, Anatoxin-a Producing Tychonema sp. in Mesotrophic Lake Tegel, Berlin.

Fastner J, Beulker C, Geiser B, Hoffmann A, Kröger R, Teske K, Hoppe J, Mundhenk L, Neurath H, Sagebiel D, Chorus I.

Toxins (Basel). 2018 Jan 31;10(2). pii: E60. doi: 10.3390/toxins10020060.


Interspecies diversity of chloride channel regulators, calcium-activated 3 genes.

Mundhenk L, Erickson NA, Klymiuk N, Gruber AD.

PLoS One. 2018 Jan 18;13(1):e0191512. doi: 10.1371/journal.pone.0191512. eCollection 2018.


How Effective Is Tacrolimus in the Imiquimod-Induced Mouse Model of Psoriasis?

Pischon H, Radbruch M, Ostrowski A, Schumacher F, Hönzke S, Kleuser B, Hedtrich S, Fluhr JW, Gruber AD, Mundhenk L.

J Invest Dermatol. 2018 Feb;138(2):455-458. doi: 10.1016/j.jid.2017.09.019. Epub 2017 Sep 22. No abstract available.


Dendritic Core-Multishell Nanocarriers in Murine Models of Healthy and Atopic Skin.

Radbruch M, Pischon H, Ostrowski A, Volz P, Brodwolf R, Neumann F, Unbehauen M, Kleuser B, Haag R, Ma N, Alexiev U, Mundhenk L, Gruber AD.

Nanoscale Res Lett. 2017 Dec;12(1):64. doi: 10.1186/s11671-017-1835-0. Epub 2017 Jan 23.


Stratum corneum targeting by dendritic core-multishell-nanocarriers in a mouse model of psoriasis.

Pischon H, Radbruch M, Ostrowski A, Volz P, Gerecke C, Unbehauen M, Hönzke S, Hedtrich S, Fluhr JW, Haag R, Kleuser B, Alexiev U, Gruber AD, Mundhenk L.

Nanomedicine. 2017 Jan;13(1):317-327. doi: 10.1016/j.nano.2016.09.004. Epub 2016 Oct 1.


Influence of Th2 Cytokines on the Cornified Envelope, Tight Junction Proteins, and ß-Defensins in Filaggrin-Deficient Skin Equivalents.

Hönzke S, Wallmeyer L, Ostrowski A, Radbruch M, Mundhenk L, Schäfer-Korting M, Hedtrich S.

J Invest Dermatol. 2016 Mar;136(3):631-639. doi: 10.1016/j.jid.2015.11.007. Epub 2015 Nov 19.


Role of goblet cell protein CLCA1 in murine DSS colitis.

Erickson NA, Mundhenk L, Giovannini S, Glauben R, Heimesaat MM, Gruber AD.

J Inflamm (Lond). 2016 Feb 4;13:5. doi: 10.1186/s12950-016-0113-8. eCollection 2016.


Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype.

Plog S, Klymiuk N, Binder S, Van Hook MJ, Thoreson WB, Gruber AD, Mundhenk L.

PLoS One. 2015 Oct 16;10(10):e0140050. doi: 10.1371/journal.pone.0140050. eCollection 2015.


The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice.

Erickson NA, Nyström EE, Mundhenk L, Arike L, Glauben R, Heimesaat MM, Fischer A, Bereswill S, Birchenough GM, Gruber AD, Johansson ME.

PLoS One. 2015 Jul 10;10(7):e0131991. doi: 10.1371/journal.pone.0131991. eCollection 2015.


Overview about the localization of nanoparticles in tissue and cellular context by different imaging techniques.

Ostrowski A, Nordmeyer D, Boreham A, Holzhausen C, Mundhenk L, Graf C, Meinke MC, Vogt A, Hadam S, Lademann J, Rühl E, Alexiev U, Gruber AD.

Beilstein J Nanotechnol. 2015 Jan 23;6:263-80. doi: 10.3762/bjnano.6.25. eCollection 2015. Review.


[A gastrointestinal stromal tumour of the caecum in a pony with colic].

Rapp M, Schmitz RR, Meyer A, Mundhenk L, Gehlen H.

Tierarztl Prax Ausg G Grosstiere Nutztiere. 2014;42(5):305-10. German.


AHAPS-functionalized silica nanoparticles do not modulate allergic contact dermatitis in mice.

Ostrowski A, Nordmeyer D, Mundhenk L, Fluhr JW, Lademann J, Graf C, Rühl E, Gruber AD.

Nanoscale Res Lett. 2014 Sep 24;9(1):524. doi: 10.1186/1556-276X-9-524. eCollection 2014.


Murine CLCA5 is uniquely expressed in distinct niches of airway epithelial cells.

Dietert K, Mundhenk L, Erickson NA, Reppe K, Hocke AC, Kummer W, Witzenrath M, Gruber AD.

Histochem Cell Biol. 2015 Mar;143(3):277-87. doi: 10.1007/s00418-014-1279-x. Epub 2014 Sep 12.


mCLCA3 modulates IL-17 and CXCL-1 induction and leukocyte recruitment in murine Staphylococcus aureus pneumonia.

Dietert K, Reppe K, Mundhenk L, Witzenrath M, Gruber AD.

PLoS One. 2014 Jul 17;9(7):e102606. doi: 10.1371/journal.pone.0102606. eCollection 2014.


Skin barrier disruptions in tape stripped and allergic dermatitis models have no effect on dermal penetration and systemic distribution of AHAPS-functionalized silica nanoparticles.

Ostrowski A, Nordmeyer D, Boreham A, Brodwolf R, Mundhenk L, Fluhr JW, Lademann J, Graf C, Rühl E, Alexiev U, Gruber AD.

Nanomedicine. 2014 Oct;10(7):1571-81. doi: 10.1016/j.nano.2014.04.004. Epub 2014 Apr 22.


Synthesis and biological evaluation of radio and dye labeled amino functionalized dendritic polyglycerol sulfates as multivalent anti-inflammatory compounds.

Gröger D, Paulus F, Licha K, Welker P, Weinhart M, Holzhausen C, Mundhenk L, Gruber AD, Abram U, Haag R.

Bioconjug Chem. 2013 Sep 18;24(9):1507-14. doi: 10.1021/bc400047f. Epub 2013 Aug 22.


Tissue and cellular localization of nanoparticles using ³⁵S labeling and light microscopic autoradiography.

Holzhausen C, Gröger D, Mundhenk L, Welker P, Haag R, Gruber AD.

Nanomedicine. 2013 May;9(4):465-8. doi: 10.1016/j.nano.2013.02.003. Epub 2013 Feb 19.


Synthesis of porcine pCLCA2 protein during late differentiation of keratinocytes of epidermis and hair follicle inner root sheath.

Plog S, Mundhenk L, Langbein L, Gruber AD.

Cell Tissue Res. 2012 Dec;350(3):445-53. doi: 10.1007/s00441-012-1482-9. Epub 2012 Sep 12.


Iron overload syndrome in the black rhinoceros (Diceros bicornis): microscopical lesions and comparison with other rhinoceros species.

Olias P, Mundhenk L, Bothe M, Ochs A, Gruber AD, Klopfleisch R.

J Comp Pathol. 2012 Nov;147(4):542-9. doi: 10.1016/j.jcpa.2012.07.005. Epub 2012 Aug 27.


mCLCA3 does not contribute to calcium-activated chloride conductance in murine airways.

Mundhenk L, Johannesson B, Anagnostopoulou P, Braun J, Bothe MK, Schultz C, Mall MA, Gruber AD.

Am J Respir Cell Mol Biol. 2012 Jul;47(1):87-93. doi: 10.1165/rcmb.2010-0508OC. Epub 2012 Feb 23.


Impaired autoproteolytic cleavage of mCLCA6, a murine integral membrane protein expressed in enterocytes, leads to cleavage at the plasma membrane instead of the endoplasmic reticulum.

Bothe MK, Mundhenk L, Beck CL, Kaup M, Gruber AD.

Mol Cells. 2012 Mar;33(3):251-7. doi: 10.1007/s10059-012-2217-1. Epub 2012 Feb 15.


Metastatic endocervical adenocarcinoma in a western lowland gorilla (Gorilla g. gorilla): no evidence of virus-induced carcinogenesis.

Olias P, Schulz E, Ehlers B, Ochs A, Mundhenk L, Klopfleisch R.

J Med Primatol. 2012 Apr;41(2):142-6. doi: 10.1111/j.1600-0684.2011.00533.x. Epub 2012 Jan 25.


The porcine chloride channel calcium-activated family member pCLCA4a mirrors lung expression of the human hCLCA4.

Plog S, Grötzsch T, Klymiuk N, Kobalz U, Gruber AD, Mundhenk L.

J Histochem Cytochem. 2012 Jan;60(1):45-56. doi: 10.1369/0022155411426455.


Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis.

Klymiuk N, Mundhenk L, Kraehe K, Wuensch A, Plog S, Emrich D, Langenmayer MC, Stehr M, Holzinger A, Kröner C, Richter A, Kessler B, Kurome M, Eddicks M, Nagashima H, Heinritzi K, Gruber AD, Wolf E.

J Mol Med (Berl). 2012 May;90(5):597-608. doi: 10.1007/s00109-011-0839-y. Epub 2011 Dec 15.


The murine goblet cell protein mCLCA3 is a zinc-dependent metalloprotease with autoproteolytic activity.

Bothe MK, Mundhenk L, Kaup M, Weise C, Gruber AD.

Mol Cells. 2011 Dec;32(6):535-41. doi: 10.1007/s10059-011-0158-8. Epub 2011 Nov 9.


Exploiting Fluorescence Lifetime Plasticity in FLIM: Target Molecule Localization in Cells and Tissues.

Boreham A, Kim TY, Spahn V, Stein C, Mundhenk L, Gruber AD, Haag R, Welker P, Licha K, Alexiev U.

ACS Med Chem Lett. 2011 Aug 9;2(10):724-8. doi: 10.1021/ml200092m. eCollection 2011 Oct 13.


Sheep rumen and omasum primary cultures and source epithelia: barrier function aligns with expression of tight junction proteins.

Stumpff F, Georgi MI, Mundhenk L, Rabbani I, Fromm M, Martens H, Günzel D.

J Exp Biol. 2011 Sep 1;214(Pt 17):2871-82. doi: 10.1242/jeb.055582.


Quantitative expression analyses of candidates for alternative anion conductance in cystic fibrosis mouse models.

Braun J, Mundhenk L, Range F, Gruber AD.

J Cyst Fibros. 2010 Sep;9(5):351-64. doi: 10.1016/j.jcf.2010.06.003. Epub 2010 Jul 10.


Tissue and cellular expression patterns of porcine CFTR: similarities to and differences from human CFTR.

Plog S, Mundhenk L, Bothe MK, Klymiuk N, Gruber AD.

J Histochem Cytochem. 2010 Sep;58(9):785-97. doi: 10.1369/jhc.2010.955377. Epub 2010 May 24.


Murine mCLCA5 is expressed in granular layer keratinocytes of stratified epithelia.

Braun J, Bothe MK, Mundhenk L, Beck CL, Gruber AD.

Histochem Cell Biol. 2010 Mar;133(3):285-99. doi: 10.1007/s00418-009-0667-0. Epub 2009 Dec 11.


Genomic, tissue expression, and protein characterization of pCLCA1, a putative modulator of cystic fibrosis in the pig.

Plog S, Mundhenk L, Klymiuk N, Gruber AD.

J Histochem Cytochem. 2009 Dec;57(12):1169-81. doi: 10.1369/jhc.2009.954594. Epub 2009 Sep 15.


Psittacid herpesvirus DNA in a pancreatic duct carcinoma in a macaw.

Mundhenk L, Müller K, Lierz M, Lüschow D, Stahl T, Müller H, Johne R.

Vet Rec. 2009 Mar 7;164(10):306-8. No abstract available.


Murine mCLCA6 is an integral apical membrane protein of non-goblet cell enterocytes and co-localizes with the cystic fibrosis transmembrane conductance regulator.

Bothe MK, Braun J, Mundhenk L, Gruber AD.

J Histochem Cytochem. 2008 May;56(5):495-509. doi: 10.1369/jhc.2008.950592. Epub 2008 Feb 18.


Both cleavage products of the mCLCA3 protein are secreted soluble proteins.

Mundhenk L, Alfalah M, Elble RC, Pauli BU, Naim HY, Gruber AD.

J Biol Chem. 2006 Oct 6;281(40):30072-80. Epub 2006 Aug 8.


The putative chloride channel hCLCA2 has a single C-terminal transmembrane segment.

Elble RC, Walia V, Cheng HC, Connon CJ, Mundhenk L, Gruber AD, Pauli BU.

J Biol Chem. 2006 Oct 6;281(40):29448-54. Epub 2006 Jul 27.


Overexpression of eCLCA1 in small airways of horses with recurrent airway obstruction.

Anton F, Leverkoehne I, Mundhenk L, Thoreson WB, Gruber AD.

J Histochem Cytochem. 2005 Aug;53(8):1011-21. Epub 2005 May 6.

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