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Items: 1 to 50 of 61

1.

Imaging axon regeneration within synthetic nerve conduits.

Fogli B, Corthout N, Kerstens A, Bosse F, Klimaschewski L, Munck S, Schweigreiter R.

Sci Rep. 2019 Jul 12;9(1):10095. doi: 10.1038/s41598-019-46579-w.

2.

Factors influencing Urate Lowering Therapies prescription for asymptomatic hyperuricemia by general practitioners: a qualitative study.

Tourzel E, Munck S, Fournier JP, Maisonneuve H.

Int J Clin Pract. 2019 Sep;73(9):1-11. doi: 10.1111/ijcp.13383. Epub 2019 Jun 28.

PMID:
31250954
3.

Disruption of endocytosis through chemical inhibition of clathrin heavy chain function.

Dejonghe W, Sharma I, Denoo B, De Munck S, Lu Q, Mishev K, Bulut H, Mylle E, De Rycke R, Vasileva M, Savatin DV, Nerinckx W, Staes A, Drozdzecki A, Audenaert D, Yperman K, Madder A, Friml J, Van Damme D, Gevaert K, Haucke V, Savvides SN, Winne J, Russinova E.

Nat Chem Biol. 2019 Jun;15(6):641-649. doi: 10.1038/s41589-019-0262-1. Epub 2019 Apr 22.

PMID:
31011214
4.

Age-associated cholesterol reduction triggers brain insulin resistance by facilitating ligand-independent receptor activation and pathway desensitization.

Martín-Segura A, Ahmed T, Casadomé-Perales Á, Palomares-Perez I, Palomer E, Kerstens A, Munck S, Balschun D, Dotti CG.

Aging Cell. 2019 Jun;18(3):e12932. doi: 10.1111/acel.12932. Epub 2019 Mar 18.

5.

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.

Vriens K, Christen S, Parik S, Broekaert D, Yoshinaga K, Talebi A, Dehairs J, Escalona-Noguero C, Schmieder R, Cornfield T, Charlton C, Romero-Pérez L, Rossi M, Rinaldi G, Orth MF, Boon R, Kerstens A, Kwan SY, Faubert B, Méndez-Lucas A, Kopitz CC, Chen T, Fernandez-Garcia J, Duarte JAG, Schmitz AA, Steigemann P, Najimi M, Hägebarth A, Van Ginderachter JA, Sokal E, Gotoh N, Wong KK, Verfaillie C, Derua R, Munck S, Yuneva M, Beretta L, DeBerardinis RJ, Swinnen JV, Hodson L, Cassiman D, Verslype C, Christian S, Grünewald S, Grünewald TGP, Fendt SM.

Nature. 2019 Feb;566(7744):403-406. doi: 10.1038/s41586-019-0904-1. Epub 2019 Feb 6.

6.

Modernization of Golgi staining techniques for high-resolution, 3-dimensional imaging of individual neurons.

Vints K, Vandael D, Baatsen P, Pavie B, Vernaillen F, Corthout N, Rybakin V, Munck S, Gounko NV.

Sci Rep. 2019 Jan 15;9(1):130. doi: 10.1038/s41598-018-37377-x.

7.

A Label-free Multicolor Optical Surface Tomography (ALMOST) imaging method for nontransparent 3D samples.

Kerstens A, Corthout N, Pavie B, Huang Z, Vernaillen F, Vande Velde G, Munck S.

BMC Biol. 2019 Jan 7;17(1):1. doi: 10.1186/s12915-018-0614-4.

8.

Effect of Diet in Chronic Spontaneous Urticaria: A Systematic Review.

Cornillier H, Giraudeau B, Samimi M, Munck S, Hacard F, Jonville-Bera AP, Jegou MH, d'Acremont G, Pham BN, Chosidow O, Maruani A.

Acta Derm Venereol. 2019 Feb 1;99(2):127-132. doi: 10.2340/00015555-3015.

9.

Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors.

Mishev K, Lu Q, Denoo B, Peurois F, Dejonghe W, Hullaert J, De Rycke R, Boeren S, Bretou M, De Munck S, Sharma I, Goodman K, Kalinowska K, Storme V, Nguyen LSL, Drozdzecki A, Martins S, Nerinckx W, Audenaert D, Vert G, Madder A, Otegui MS, Isono E, Savvides SN, Annaert W, De Vries S, Cherfils J, Winne J, Russinova E.

Plant Cell. 2018 Oct;30(10):2573-2593. doi: 10.1105/tpc.18.00145. Epub 2018 Jul 17.

10.

Chronic spontaneous urticaria in children - a systematic review on interventions and comorbidities.

Cornillier H, Giraudeau B, Munck S, Hacard F, Jonville-Bera AP, d'Acremont G, Pham BN, Maruani A.

Pediatr Allergy Immunol. 2018 May;29(3):303-310. doi: 10.1111/pai.12870. Epub 2018 Mar 15. Review.

PMID:
29392757
11.

Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments.

Guix FX, Sannerud R, Berditchevski F, Arranz AM, Horré K, Snellinx A, Thathiah A, Saido T, Saito T, Rajesh S, Overduin M, Kumar-Singh S, Radaelli E, Corthout N, Colombelli J, Tosi S, Munck S, Salas IH, Annaert W, De Strooper B.

Mol Neurodegener. 2017 Mar 10;12(1):25. doi: 10.1186/s13024-017-0165-0.

12.

Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.

Espuny-Camacho I, Arranz AM, Fiers M, Snellinx A, Ando K, Munck S, Bonnefont J, Lambot L, Corthout N, Omodho L, Vanden Eynden E, Radaelli E, Tesseur I, Wray S, Ebneth A, Hardy J, Leroy K, Brion JP, Vanderhaeghen P, De Strooper B.

Neuron. 2017 Mar 8;93(5):1066-1081.e8. doi: 10.1016/j.neuron.2017.02.001. Epub 2017 Feb 23.

13.

Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF.

Felix J, Kandiah E, De Munck S, Bloch Y, van Zundert GC, Pauwels K, Dansercoer A, Novanska K, Read RJ, Bonvin AM, Vergauwen B, Verstraete K, Gutsche I, Savvides SN.

Nat Commun. 2016 Nov 7;7:13228. doi: 10.1038/ncomms13228.

14.

Inhomogeneity Based Characterization of Distribution Patterns on the Plasma Membrane.

Paparelli L, Corthout N, Pavie B, Wakefield DL, Sannerud R, Jovanovic-Talisman T, Annaert W, Munck S.

PLoS Comput Biol. 2016 Sep 7;12(9):e1005095. doi: 10.1371/journal.pcbi.1005095. eCollection 2016 Sep.

15.

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool.

Sannerud R, Esselens C, Ejsmont P, Mattera R, Rochin L, Tharkeshwar AK, De Baets G, De Wever V, Habets R, Baert V, Vermeire W, Michiels C, Groot AJ, Wouters R, Dillen K, Vints K, Baatsen P, Munck S, Derua R, Waelkens E, Basi GS, Mercken M, Vooijs M, Bollen M, Schymkowitz J, Rousseau F, Bonifacino JS, Van Niel G, De Strooper B, Annaert W.

Cell. 2016 Jun 30;166(1):193-208. doi: 10.1016/j.cell.2016.05.020. Epub 2016 Jun 9.

16.

Analyzing Protein Clusters on the Plasma Membrane: Application of Spatial Statistical Analysis Methods on Super-Resolution Microscopy Images.

Paparelli L, Corthout N, Pavie B, Annaert W, Munck S.

Adv Anat Embryol Cell Biol. 2016;219:95-122. doi: 10.1007/978-3-319-28549-8_4. Review.

PMID:
27207364
17.

Identification of drugs that restore primary cilium expression in cancer cells.

Khan NA, Willemarck N, Talebi A, Marchand A, Binda MM, Dehairs J, Rueda-Rincon N, Daniels VW, Bagadi M, Thimiri Govinda Raj DB, Vanderhoydonc F, Munck S, Chaltin P, Swinnen JV.

Oncotarget. 2016 Mar 1;7(9):9975-92. doi: 10.18632/oncotarget.7198.

18.

High-content analysis of α-synuclein aggregation and cell death in a cellular model of Parkinson's disease.

Macchi F, Deleersnijder A, Van den Haute C, Munck S, Pottel H, Michiels A, Debyser Z, Gerard M, Baekelandt V.

J Neurosci Methods. 2016 Mar 1;261:117-27. doi: 10.1016/j.jneumeth.2015.11.009. Epub 2015 Nov 24.

PMID:
26620202
19.

Hsc70-4 Deforms Membranes to Promote Synaptic Protein Turnover by Endosomal Microautophagy.

Uytterhoeven V, Lauwers E, Maes I, Miskiewicz K, Melo MN, Swerts J, Kuenen S, Wittocx R, Corthout N, Marrink SJ, Munck S, Verstreken P.

Neuron. 2015 Nov 18;88(4):735-48. doi: 10.1016/j.neuron.2015.10.012.

20.

Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models.

Huang Y, Skwarek-Maruszewska A, Horré K, Vandewyer E, Wolfs L, Snellinx A, Saito T, Radaelli E, Corthout N, Colombelli J, Lo AC, Van Aerschot L, Callaerts-Vegh Z, Trabzuni D, Bossers K, Verhaagen J, Ryten M, Munck S, D'Hooge R, Swaab DF, Hardy J, Saido TC, De Strooper B, Thathiah A.

Sci Transl Med. 2015 Oct 14;7(309):309ra164. doi: 10.1126/scitranslmed.aab3492.

PMID:
26468326
21.

High content analysis at single cell level identifies different cellular responses dependent on nanomaterial concentrations.

Manshian BB, Munck S, Agostinis P, Himmelreich U, Soenen SJ.

Sci Rep. 2015 Sep 8;5:13890. doi: 10.1038/srep13890.

22.

Antagonistic Effects of BACE1 and APH1B-γ-Secretase Control Axonal Guidance by Regulating Growth Cone Collapse.

Barão S, Gärtner A, Leyva-Díaz E, Demyanenko G, Munck S, Vanhoutvin T, Zhou L, Schachner M, López-Bendito G, Maness PF, De Strooper B.

Cell Rep. 2015 Sep 1;12(9):1367-76. doi: 10.1016/j.celrep.2015.07.059. Epub 2015 Aug 20.

23.

Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1.

Felix J, De Munck S, Verstraete K, Meuris L, Callewaert N, Elegheert J, Savvides SN.

Structure. 2015 Sep 1;23(9):1621-1631. doi: 10.1016/j.str.2015.06.019. Epub 2015 Jul 30.

24.

[Factors associated with investment in an office medicine project by general practice residents].

Munck S, Massin S, Hofliger P, Darmon D.

Sante Publique. 2015 Jan-Feb;27(1):49-58. French.

PMID:
26164955
25.

High-content imaging and gene expression analysis to study cell-nanomaterial interactions: the effect of surface hydrophobicity.

Manshian BB, Moyano DF, Corthout N, Munck S, Himmelreich U, Rotello VM, Soenen SJ.

Biomaterials. 2014 Dec;35(37):9941-9950. doi: 10.1016/j.biomaterials.2014.08.031. Epub 2014 Sep 15.

PMID:
25218858
26.

HDAC6 is a Bruchpilot deacetylase that facilitates neurotransmitter release.

Miskiewicz K, Jose LE, Yeshaw WM, Valadas JS, Swerts J, Munck S, Feiguin F, Dermaut B, Verstreken P.

Cell Rep. 2014 Jul 10;8(1):94-102. doi: 10.1016/j.celrep.2014.05.051. Epub 2014 Jun 26.

27.

Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents.

Martin MG, Ahmed T, Korovaichuk A, Venero C, Menchón SA, Salas I, Munck S, Herreras O, Balschun D, Dotti CG.

EMBO Mol Med. 2014 Jul;6(7):902-17. doi: 10.15252/emmm.201303711.

28.

The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.

Schiefermeier N, Scheffler JM, de Araujo ME, Stasyk T, Yordanov T, Ebner HL, Offterdinger M, Munck S, Hess MW, Wickström SA, Lange A, Wunderlich W, Fässler R, Teis D, Huber LA.

J Cell Biol. 2014 May 26;205(4):525-40. doi: 10.1083/jcb.201310043. Epub 2014 May 19.

29.

Regulation of branching dynamics by axon-intrinsic asymmetries in Tyrosine Kinase Receptor signaling.

Zschätzsch M, Oliva C, Langen M, De Geest N, Ozel MN, Williamson WR, Lemon WC, Soldano A, Munck S, Hiesinger PR, Sanchez-Soriano N, Hassan BA.

Elife. 2014 Apr 22;3:e01699. doi: 10.7554/eLife.01699.

30.

The fragile X protein binds mRNAs involved in cancer progression and modulates metastasis formation.

Lucá R, Averna M, Zalfa F, Vecchi M, Bianchi F, La Fata G, Del Nonno F, Nardacci R, Bianchi M, Nuciforo P, Munck S, Parrella P, Moura R, Signori E, Alston R, Kuchnio A, Farace MG, Fazio VM, Piacentini M, De Strooper B, Achsel T, Neri G, Neven P, Evans DG, Carmeliet P, Mazzone M, Bagni C.

EMBO Mol Med. 2013 Oct;5(10):1523-36. doi: 10.1002/emmm.201302847. Epub 2013 Sep 16. Erratum in: EMBO Mol Med. 2014 Apr;6(4):567.

31.

Role of PFKFB3-driven glycolysis in vessel sprouting.

De Bock K, Georgiadou M, Schoors S, Kuchnio A, Wong BW, Cantelmo AR, Quaegebeur A, Ghesquière B, Cauwenberghs S, Eelen G, Phng LK, Betz I, Tembuyser B, Brepoels K, Welti J, Geudens I, Segura I, Cruys B, Bifari F, Decimo I, Blanco R, Wyns S, Vangindertael J, Rocha S, Collins RT, Munck S, Daelemans D, Imamura H, Devlieger R, Rider M, Van Veldhoven PP, Schuit F, Bartrons R, Hofkens J, Fraisl P, Telang S, Deberardinis RJ, Schoonjans L, Vinckier S, Chesney J, Gerhardt H, Dewerchin M, Carmeliet P.

Cell. 2013 Aug 1;154(3):651-63. doi: 10.1016/j.cell.2013.06.037.

32.

Integration of Microfractionation, qNMR and zebrafish screening for the in vivo bioassay-guided isolation and quantitative bioactivity analysis of natural products.

Bohni N, Cordero-Maldonado ML, Maes J, Siverio-Mota D, Marcourt L, Munck S, Kamuhabwa AR, Moshi MJ, Esguerra CV, de Witte PA, Crawford AD, Wolfender JL.

PLoS One. 2013 May 21;8(5):e64006. doi: 10.1371/journal.pone.0064006. Print 2013.

33.

Rer1p maintains ciliary length and signaling by regulating γ-secretase activity and Foxj1a levels.

Jurisch-Yaksi N, Rose AJ, Lu H, Raemaekers T, Munck S, Baatsen P, Baert V, Vermeire W, Scales SJ, Verleyen D, Vandepoel R, Tylzanowski P, Yaksi E, de Ravel T, Yost HJ, Froyen G, Arrington CB, Annaert W.

J Cell Biol. 2013 Mar 18;200(6):709-20. doi: 10.1083/jcb.201208175. Epub 2013 Mar 11.

34.

β-arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease.

Thathiah A, Horré K, Snellinx A, Vandewyer E, Huang Y, Ciesielska M, De Kloe G, Munck S, De Strooper B.

Nat Med. 2013 Jan;19(1):43-9. doi: 10.1038/nm.3023. Epub 2012 Dec 2.

PMID:
23202293
35.

Loss of PPP2R2A inhibits homologous recombination DNA repair and predicts tumor sensitivity to PARP inhibition.

Kalev P, Simicek M, Vazquez I, Munck S, Chen L, Soin T, Danda N, Chen W, Sablina A.

Cancer Res. 2012 Dec 15;72(24):6414-24. doi: 10.1158/0008-5472.CAN-12-1667. Epub 2012 Oct 18.

36.

A pilot randomized controlled trial of an early multidisciplinary model to prevent disability following traumatic injury.

Browne AL, Appleton S, Fong K, Wood F, Coll F, de Munck S, Newnham E, Schug SA.

Disabil Rehabil. 2013 Jul;35(14):1149-63. doi: 10.3109/09638288.2012.721047. Epub 2012 Oct 22.

PMID:
23083416
37.

Comparative motif discovery combined with comparative transcriptomics yields accurate targetome and enhancer predictions.

Naval-Sánchez M, Potier D, Haagen L, Sánchez M, Munck S, Van de Sande B, Casares F, Christiaens V, Aerts S.

Genome Res. 2013 Jan;23(1):74-88. doi: 10.1101/gr.140426.112. Epub 2012 Oct 15.

38.

KIF1Bβ transports dendritically localized mRNPs in neurons and is recruited to synapses in an activity-dependent manner.

Charalambous DC, Pasciuto E, Mercaldo V, Pilo Boyl P, Munck S, Bagni C, Santama N.

Cell Mol Life Sci. 2013 Jan;70(2):335-56. doi: 10.1007/s00018-012-1108-0. Epub 2012 Sep 4.

PMID:
22945799
39.

Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells.

Coen K, Flannagan RS, Baron S, Carraro-Lacroix LR, Wang D, Vermeire W, Michiels C, Munck S, Baert V, Sugita S, Wuytack F, Hiesinger PR, Grinstein S, Annaert W.

J Cell Biol. 2012 Jul 9;198(1):23-35. doi: 10.1083/jcb.201201076. Epub 2012 Jul 2.

40.

Identification and characterization of MEL-3, a novel AR antagonist that suppresses prostate cancer cell growth.

Helsen C, Marchand A, Chaltin P, Munck S, Voet A, Verstuyf A, Claessens F.

Mol Cancer Ther. 2012 Jun;11(6):1257-68. doi: 10.1158/1535-7163.MCT-11-0763. Epub 2012 Apr 10.

41.

Sub-diffraction imaging on standard microscopes through photobleaching microscopy with non-linear processing.

Munck S, Miskiewicz K, Sannerud R, Menchon SA, Jose L, Heintzmann R, Verstreken P, Annaert W.

J Cell Sci. 2012 May 1;125(Pt 9):2257-66. doi: 10.1242/jcs.098939. Epub 2012 Feb 22.

42.

N-cadherin specifies first asymmetry in developing neurons.

Gärtner A, Fornasiero EF, Munck S, Vennekens K, Seuntjens E, Huttner WB, Valtorta F, Dotti CG.

EMBO J. 2012 Apr 18;31(8):1893-903. doi: 10.1038/emboj.2012.41. Epub 2012 Feb 21.

43.

Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-β production by altering Nicastrin maturation and intracellular localization.

Michaki V, Guix FX, Vennekens K, Munck S, Dingwall C, Davis JB, Townsend DM, Tew KD, Feiguin F, De Strooper B, Dotti CG, Wahle T.

J Biol Chem. 2012 Jan 6;287(2):1100-11. doi: 10.1074/jbc.M111.288258. Epub 2011 Nov 15.

44.

Cytokinesis remnants define first neuronal asymmetry in vivo.

Pollarolo G, Schulz JG, Munck S, Dotti CG.

Nat Neurosci. 2011 Nov 13;14(12):1525-33. doi: 10.1038/nn.2976.

PMID:
22081156
45.

ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1.

Sannerud R, Declerck I, Peric A, Raemaekers T, Menendez G, Zhou L, Veerle B, Coen K, Munck S, De Strooper B, Schiavo G, Annaert W.

Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):E559-68. doi: 10.1073/pnas.1100745108. Epub 2011 Aug 8.

46.

Zebrafish bioassay-guided natural product discovery: isolation of angiogenesis inhibitors from East African medicinal plants.

Crawford AD, Liekens S, Kamuhabwa AR, Maes J, Munck S, Busson R, Rozenski J, Esguerra CV, de Witte PA.

PLoS One. 2011 Feb 17;6(2):e14694. doi: 10.1371/journal.pone.0014694.

47.

De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation.

Rysman E, Brusselmans K, Scheys K, Timmermans L, Derua R, Munck S, Van Veldhoven PP, Waltregny D, Daniëls VW, Machiels J, Vanderhoydonc F, Smans K, Waelkens E, Verhoeven G, Swinnen JV.

Cancer Res. 2010 Oct 15;70(20):8117-26. doi: 10.1158/0008-5472.CAN-09-3871. Epub 2010 Sep 28.

48.

A comparative follow-up study of aftercare and compliance of suicide attempters following standardized psychosocial assessment.

Wittouck C, De Munck S, Portzky G, Van Rijsselberghe L, Van Autreve S, van Heeringen K.

Arch Suicide Res. 2010;14(2):135-45. doi: 10.1080/13811111003704746.

PMID:
20455149
49.

Inhibition of FK506 binding proteins reduces alpha-synuclein aggregation and Parkinson's disease-like pathology.

Gerard M, Deleersnijder A, Daniëls V, Schreurs S, Munck S, Reumers V, Pottel H, Engelborghs Y, Van den Haute C, Taymans JM, Debyser Z, Baekelandt V.

J Neurosci. 2010 Feb 17;30(7):2454-63. doi: 10.1523/JNEUROSCI.5983-09.2010.

50.

Epidemiological trends in attempted suicide in adolescents and young adults between 1996 and 2004.

De Munck S, Portzky G, Van Heeringen K.

Crisis. 2009;30(3):115-9. doi: 10.1027/0227-5910.30.3.115.

PMID:
19767266

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