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Items: 1 to 50 of 124

1.

A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors.

Hartmann J, Münch RC, Freiling RT, Schneider IC, Dreier B, Samukange W, Koch J, Seeger MA, Plückthun A, Buchholz CJ.

Mol Ther Methods Clin Dev. 2018 Jul 6;10:128-143. doi: 10.1016/j.omtm.2018.07.001. eCollection 2018 Sep 21.

2.

Subspecies in the global human gut microbiome.

Costea PI, Coelho LP, Sunagawa S, Munch R, Huerta-Cepas J, Forslund K, Hildebrand F, Kushugulova A, Zeller G, Bork P.

Mol Syst Biol. 2017 Dec 14;13(12):960. doi: 10.15252/msb.20177589.

3.

Retinal cell death dependent reactive proliferative gliosis in the mouse retina.

Sardar Pasha SPB, Münch R, Schäfer P, Oertel P, Sykes AM, Zhu Y, Karl MO.

Sci Rep. 2017 Aug 25;7(1):9517. doi: 10.1038/s41598-017-09743-8.

4.

Covalent coupling of high-affinity ligands to the surface of viral vector particles by protein trans-splicing mediates cell type-specific gene transfer.

Muik A, Reul J, Friedel T, Muth A, Hartmann KP, Schneider IC, Münch RC, Buchholz CJ.

Biomaterials. 2017 Nov;144:84-94. doi: 10.1016/j.biomaterials.2017.07.032. Epub 2017 Jul 25.

PMID:
28825979
5.

metaSNV: A tool for metagenomic strain level analysis.

Costea PI, Munch R, Coelho LP, Paoli L, Sunagawa S, Bork P.

PLoS One. 2017 Jul 28;12(7):e0182392. doi: 10.1371/journal.pone.0182392. eCollection 2017.

6.

A Precise Temperature-Responsive Bistable Switch Controlling Yersinia Virulence.

Nuss AM, Schuster F, Roselius L, Klein J, Bücker R, Herbst K, Heroven AK, Pisano F, Wittmann C, Münch R, Müller J, Jahn D, Dersch P.

PLoS Pathog. 2016 Dec 22;12(12):e1006091. doi: 10.1371/journal.ppat.1006091. eCollection 2016 Dec.

7.

Enhanced lysis by bispecific oncolytic measles viruses simultaneously using HER2/neu or EpCAM as target receptors.

Hanauer JR, Gottschlich L, Riehl D, Rusch T, Koch V, Friedrich K, Hutzler S, Prüfer S, Friedel T, Hanschmann KM, Münch RC, Jost C, Plückthun A, Cichutek K, Buchholz CJ, Mühlebach MD.

Mol Ther Oncolytics. 2016 Feb 24;3:16003. doi: 10.1038/mto.2016.3. eCollection 2016.

8.

Exclusive Transduction of Human CD4+ T Cells upon Systemic Delivery of CD4-Targeted Lentiviral Vectors.

Zhou Q, Uhlig KM, Muth A, Kimpel J, Lévy C, Münch RC, Seifried J, Pfeiffer A, Trkola A, Coulibaly C, von Laer D, Wels WS, Hartwig UF, Verhoeyen E, Buchholz CJ.

J Immunol. 2015 Sep 1;195(5):2493-501. doi: 10.4049/jimmunol.1500956. Epub 2015 Jul 31.

9.

Polar Fixation of Plasmids during Recombinant Protein Production in Bacillus megaterium Results in Population Heterogeneity.

Münch KM, Müller J, Wienecke S, Bergmann S, Heyber S, Biedendieck R, Münch R, Jahn D.

Appl Environ Microbiol. 2015 Sep 1;81(17):5976-86. doi: 10.1128/AEM.00807-15. Epub 2015 Jun 26.

10.

In vitro incorporation of a cell-binding protein to a lentiviral vector using an engineered split intein enables targeted delivery of genetic cargo.

Chamoun-Emanuelli AM, Wright G, Roger S 3rd, Münch RC, Buchholz CJ, Chen Z.

Biotechnol Bioeng. 2015 Dec;112(12):2611-7. doi: 10.1002/bit.25685. Epub 2015 Aug 12.

PMID:
26108964
11.

Off-target-free gene delivery by affinity-purified receptor-targeted viral vectors.

Münch RC, Muth A, Muik A, Friedel T, Schmatz J, Dreier B, Trkola A, Plückthun A, Büning H, Buchholz CJ.

Nat Commun. 2015 Feb 10;6:6246. doi: 10.1038/ncomms7246.

PMID:
25665714
12.

'Isotopo' a database application for facile analysis and management of mass isotopomer data.

Ahmed Z, Zeeshan S, Huber C, Hensel M, Schomburg D, Münch R, Eylert E, Eisenreich W, Dandekar T.

Database (Oxford). 2014 Sep 9;2014. pii: bau077. doi: 10.1093/database/bau077. Print 2014.

13.

Modelling and analysis of a gene-regulatory feed-forward loop with basal expression of the second regulator.

Roselius L, Langemann D, Müller J, Hense BA, Filges S, Jahn D, Münch R.

J Theor Biol. 2014 Dec 21;363:290-9. doi: 10.1016/j.jtbi.2014.08.043. Epub 2014 Sep 1.

PMID:
25193818
14.

Deodorization of garlic breath volatiles by food and food components.

Munch R, Barringer SA.

J Food Sci. 2014 Apr;79(4):C526-33. doi: 10.1111/1750-3841.12394. Epub 2014 Mar 4.

PMID:
24592995
15.

Specific gene delivery to liver sinusoidal and artery endothelial cells.

Abel T, El Filali E, Waern J, Schneider IC, Yuan Q, Münch RC, Hick M, Warnecke G, Madrahimov N, Kontermann RE, Schüttrumpf J, Müller UC, Seppen J, Ott M, Buchholz CJ.

Blood. 2013 Sep 19;122(12):2030-8. doi: 10.1182/blood-2012-11-468579. Epub 2013 Jul 24.

16.

Software LS-MIDA for efficient mass isotopomer distribution analysis in metabolic modelling.

Ahmed Z, Zeeshan S, Huber C, Hensel M, Schomburg D, Münch R, Eisenreich W, Dandekar T.

BMC Bioinformatics. 2013 Jul 9;14:218. doi: 10.1186/1471-2105-14-218.

17.

You are what you talk: quorum sensing induces individual morphologies and cell division modes in Dinoroseobacter shibae.

Patzelt D, Wang H, Buchholz I, Rohde M, Gröbe L, Pradella S, Neumann A, Schulz S, Heyber S, Münch K, Münch R, Jahn D, Wagner-Döbler I, Tomasch J.

ISME J. 2013 Dec;7(12):2274-86. doi: 10.1038/ismej.2013.107. Epub 2013 Jul 4.

18.

The receptor attachment function of measles virus hemagglutinin can be replaced with an autonomous protein that binds Her2/neu while maintaining its fusion-helper function.

Rasbach A, Abel T, Münch RC, Boller K, Schneider-Schaulies J, Buchholz CJ.

J Virol. 2013 Jun;87(11):6246-56. doi: 10.1128/JVI.03298-12. Epub 2013 Mar 27.

19.

DARPin-targeting of measles virus: unique bispecificity, effective oncolysis, and enhanced safety.

Friedrich K, Hanauer JR, Prüfer S, Münch RC, Völker I, Filippis C, Jost C, Hanschmann KM, Cattaneo R, Peng KW, Plückthun A, Buchholz CJ, Cichutek K, Mühlebach MD.

Mol Ther. 2013 Apr;21(4):849-59. doi: 10.1038/mt.2013.16. Epub 2013 Feb 5.

20.

Crp induces switching of the CsrB and CsrC RNAs in Yersinia pseudotuberculosis and links nutritional status to virulence.

Heroven AK, Sest M, Pisano F, Scheb-Wetzel M, Steinmann R, Böhme K, Klein J, Münch R, Schomburg D, Dersch P.

Front Cell Infect Microbiol. 2012 Dec 17;2:158. doi: 10.3389/fcimb.2012.00158. eCollection 2012.

21.

Displaying high-affinity ligands on adeno-associated viral vectors enables tumor cell-specific and safe gene transfer.

Münch RC, Janicki H, Völker I, Rasbach A, Hallek M, Büning H, Buchholz CJ.

Mol Ther. 2013 Jan;21(1):109-18. doi: 10.1038/mt.2012.186. Epub 2012 Sep 11.

22.

TLM-Tracker: software for cell segmentation, tracking and lineage analysis in time-lapse microscopy movies.

Klein J, Leupold S, Biegler I, Biedendieck R, Münch R, Jahn D.

Bioinformatics. 2012 Sep 1;28(17):2276-7. doi: 10.1093/bioinformatics/bts424. Epub 2012 Jul 5.

PMID:
22772947
23.

Effects of the ERES pathogenicity region regulator Ralp3 on Streptococcus pyogenes serotype M49 virulence factor expression.

Siemens N, Fiedler T, Normann J, Klein J, Münch R, Patenge N, Kreikemeyer B.

J Bacteriol. 2012 Jul;194(14):3618-26. doi: 10.1128/JB.00227-12. Epub 2012 Apr 27.

24.

InFiRe -- a novel computational method for the identification of insertion sites in transposon mutagenized bacterial genomes.

Shevchuk O, Roselius L, Günther G, Klein J, Jahn D, Steinert M, Münch R.

Bioinformatics. 2012 Feb 1;28(3):306-10. doi: 10.1093/bioinformatics/btr672. Epub 2011 Dec 6.

PMID:
22155866
25.

A short story about a big magic bug.

Bunk B, Schulz A, Stammen S, Münch R, Warren MJ, Rohde M, Jahn D, Biedendieck R.

Bioeng Bugs. 2010 Mar-Apr;1(2):85-91. doi: 10.4161/bbug.1.2.11101. Epub 2010 Jan 4.

26.

GeneReporter--sequence-based document retrieval and annotation.

Bartsch A, Bunk B, Haddad I, Klein J, Münch R, Johl T, Kärst U, Jänsch L, Jahn D, Retter I.

Bioinformatics. 2011 Apr 1;27(7):1034-5. doi: 10.1093/bioinformatics/btr047. Epub 2011 Feb 9.

27.

DARPins: an efficient targeting domain for lentiviral vectors.

Münch RC, Mühlebach MD, Schaser T, Kneissl S, Jost C, Plückthun A, Cichutek K, Buchholz CJ.

Mol Ther. 2011 Apr;19(4):686-93. doi: 10.1038/mt.2010.298. Epub 2011 Jan 11.

28.

Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors.

Anliker B, Abel T, Kneissl S, Hlavaty J, Caputi A, Brynza J, Schneider IC, Münch RC, Petznek H, Kontermann RE, Koehl U, Johnston IC, Keinänen K, Müller UC, Hohenadl C, Monyer H, Cichutek K, Buchholz CJ.

Nat Methods. 2010 Nov;7(11):929-35. doi: 10.1038/nmeth.1514. Epub 2010 Oct 10.

PMID:
20935652
29.

Anaerobic adaptation in Pseudomonas aeruginosa: definition of the Anr and Dnr regulons.

Trunk K, Benkert B, Quäck N, Münch R, Scheer M, Garbe J, Jänsch L, Trost M, Wehland J, Buer J, Jahn M, Schobert M, Jahn D.

Environ Microbiol. 2010 Jun;12(6):1719-33. doi: 10.1111/j.1462-2920.2010.02252.x.

PMID:
20553552
30.

Relapsing fever Borrelia binds to neolacto glycans and mediates rosetting of human erythrocytes.

Guo BP, Teneberg S, Münch R, Terunuma D, Hatano K, Matsuoka K, Angström J, Borén T, Bergström S.

Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19280-5. doi: 10.1073/pnas.0905470106. Epub 2009 Nov 2.

31.

PRODORIC (release 2009): a database and tool platform for the analysis of gene regulation in prokaryotes.

Grote A, Klein J, Retter I, Haddad I, Behling S, Bunk B, Biegler I, Yarmolinetz S, Jahn D, Münch R.

Nucleic Acids Res. 2009 Jan;37(Database issue):D61-5. doi: 10.1093/nar/gkn837. Epub 2008 Oct 30.

32.

ROSY--a flexible and universal database and bioinformatics tool platform for Roseobacter related species.

Pommerenke C, Gabriel I, Bunk B, Münch R, Haddad I, Tielen P, Wagner-Döbler I, Jahn D.

In Silico Biol. 2008;8(2):177-86.

PMID:
18928204
33.

Strepto-DB, a database for comparative genomics of group A (GAS) and B (GBS) streptococci, implemented with the novel database platform 'Open Genome Resource' (OGeR).

Klein J, Münch R, Biegler I, Haddad I, Retter I, Jahn D.

Nucleic Acids Res. 2009 Jan;37(Database issue):D494-8. doi: 10.1093/nar/gkn674. Epub 2008 Oct 14.

34.

ProdoNet: identification and visualization of prokaryotic gene regulatory and metabolic networks.

Klein J, Leupold S, Münch R, Pommerenke C, Johl T, Kärst U, Jänsch L, Jahn D, Retter I.

Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W460-4. doi: 10.1093/nar/gkn217. Epub 2008 Apr 25.

35.

SYSTOMONAS--an integrated database for systems biology analysis of Pseudomonas.

Choi C, Münch R, Leupold S, Klein J, Siegel I, Thielen B, Benkert B, Kucklick M, Schobert M, Barthelmes J, Ebeling C, Haddad I, Scheer M, Grote A, Hiller K, Bunk B, Schreiber K, Retter I, Schomburg D, Jahn D.

Nucleic Acids Res. 2007 Jan;35(Database issue):D533-7.

36.

MetaQuant: a tool for the automatic quantification of GC/MS-based metabolome data.

Bunk B, Kucklick M, Jonas R, Münch R, Schobert M, Jahn D, Hiller K.

Bioinformatics. 2006 Dec 1;22(23):2962-5. Epub 2006 Oct 17.

PMID:
17046977
37.

RhlR expression in Pseudomonas aeruginosa is modulated by the Pseudomonas quinolone signal via PhoB-dependent and -independent pathways.

Jensen V, Löns D, Zaoui C, Bredenbruch F, Meissner A, Dieterich G, Münch R, Häussler S.

J Bacteriol. 2006 Dec;188(24):8601-6. Epub 2006 Oct 6.

38.

JVirGel 2.0: computational prediction of proteomes separated via two-dimensional gel electrophoresis under consideration of membrane and secreted proteins.

Hiller K, Grote A, Maneck M, Münch R, Jahn D.

Bioinformatics. 2006 Oct 1;22(19):2441-3. Epub 2006 Jul 26.

PMID:
16870933
39.

JProGO: a novel tool for the functional interpretation of prokaryotic microarray data using Gene Ontology information.

Scheer M, Klawonn F, Münch R, Grote A, Hiller K, Choi C, Koch I, Schobert M, Härtig E, Klages U, Jahn D.

Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W510-5.

40.

The Fnr regulon of Bacillus subtilis.

Reents H, Münch R, Dammeyer T, Jahn D, Härtig E.

J Bacteriol. 2006 Feb;188(3):1103-12.

41.

Virtual Footprint and PRODORIC: an integrative framework for regulon prediction in prokaryotes.

Münch R, Hiller K, Grote A, Scheer M, Klein J, Schobert M, Jahn D.

Bioinformatics. 2005 Nov 15;21(22):4187-9. Epub 2005 Aug 18.

PMID:
16109747
42.

JCat: a novel tool to adapt codon usage of a target gene to its potential expression host.

Grote A, Hiller K, Scheer M, Münch R, Nörtemann B, Hempel DC, Jahn D.

Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W526-31.

43.

Nanoarchaeum equitans creates functional tRNAs from separate genes for their 5'- and 3'-halves.

Randau L, Münch R, Hohn MJ, Jahn D, Söll D.

Nature. 2005 Feb 3;433(7025):537-41.

PMID:
15690044
44.

VBASE2, an integrative V gene database.

Retter I, Althaus HH, Münch R, Müller W.

Nucleic Acids Res. 2005 Jan 1;33(Database issue):D671-4.

45.

Bacillus subtilis ResD induces expression of the potential regulatory genes yclJK upon oxygen limitation.

Härtig E, Geng H, Hartmann A, Hubacek A, Münch R, Ye RW, Jahn D, Nakano MM.

J Bacteriol. 2004 Oct;186(19):6477-84.

46.

PrediSi: prediction of signal peptides and their cleavage positions.

Hiller K, Grote A, Scheer M, Münch R, Jahn D.

Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W375-9.

47.

JVirGel: Calculation of virtual two-dimensional protein gels.

Hiller K, Schobert M, Hundertmark C, Jahn D, Münch R.

Nucleic Acids Res. 2003 Jul 1;31(13):3862-5.

48.

Robert Koch.

Münch R.

Microbes Infect. 2003 Jan;5(1):69-74.

PMID:
12593975
49.

TRANSFAC: transcriptional regulation, from patterns to profiles.

Matys V, Fricke E, Geffers R, Gössling E, Haubrock M, Hehl R, Hornischer K, Karas D, Kel AE, Kel-Margoulis OV, Kloos DU, Land S, Lewicki-Potapov B, Michael H, Münch R, Reuter I, Rotert S, Saxel H, Scheer M, Thiele S, Wingender E.

Nucleic Acids Res. 2003 Jan 1;31(1):374-8.

50.

PRODORIC: prokaryotic database of gene regulation.

Münch R, Hiller K, Barg H, Heldt D, Linz S, Wingender E, Jahn D.

Nucleic Acids Res. 2003 Jan 1;31(1):266-9.

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