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Items: 1 to 50 of 85

1.

Transglutaminase in Receptor and Neurotransmitter-Regulated Functions.

Muma NA.

Med One. 2018;3(6). pii: e180012. doi: 10.20900/mo.20180012. Epub 2018 Dec 5.

2.

Receptor-stimulated transamidation induces activation of Rac1 and Cdc42 and the regulation of dendritic spines.

Mi Z, Si T, Kapadia K, Li Q, Muma NA.

Neuropharmacology. 2017 May 1;117:93-105. doi: 10.1016/j.neuropharm.2017.01.034. Epub 2017 Feb 1.

3.
4.

Serotonylation and Transamidation of Other Monoamines.

Muma NA, Mi Z.

ACS Chem Neurosci. 2015 Jul 15;6(7):961-9. doi: 10.1021/cn500329r. Epub 2015 Feb 5. Review.

PMID:
25615632
5.

GPER1 stimulation alters posttranslational modification of RGSz1 and induces desensitization of 5-HT1A receptor signaling in the rat hypothalamus.

McAllister CE, Mi Z, Mure M, Li Q, Muma NA.

Neuroendocrinology. 2014;100(2-3):228-39. doi: 10.1159/000369467. Epub 2014 Nov 7.

6.

Estradiol potentiates 8-OH-DPAT-induced sumoylation of 5-HT₁A receptor: characterization and subcellular distribution of sumoylated 5-HT₁A receptors.

Li Q, Muma NA.

Psychoneuroendocrinology. 2013 Nov;38(11):2542-53. doi: 10.1016/j.psyneuen.2013.05.016. Epub 2013 Jun 18.

7.

Estradiol accelerates the effects of fluoxetine on serotonin 1A receptor signaling.

Li Q, Sullivan NR, McAllister CE, Van de Kar LD, Muma NA.

Psychoneuroendocrinology. 2013 Jul;38(7):1145-57. doi: 10.1016/j.psyneuen.2012.11.005. Epub 2012 Dec 5.

8.

RGS proteins: impact on the treatment of depression and anxiety.

Muma NA.

Int J Neuropsychopharmacol. 2012 Oct;15(9):1199-200. doi: 10.1017/S1461145711002008. Epub 2012 Jan 25. No abstract available.

PMID:
22277123
9.

GPR30 is necessary for estradiol-induced desensitization of 5-HT1A receptor signaling in the paraventricular nucleus of the rat hypothalamus.

McAllister CE, Creech RD, Kimball PA, Muma NA, Li Q.

Psychoneuroendocrinology. 2012 Aug;37(8):1248-60. doi: 10.1016/j.psyneuen.2011.12.018. Epub 2012 Jan 20.

10.

Estradiol induces partial desensitization of serotonin 1A receptor signaling in the paraventricular nucleus of the hypothalamus and alters expression and interaction of RGSZ1 and Gαz.

Creech RD, Li Q, Carrasco GA, Van de Kar LD, Muma NA.

Neuropharmacology. 2012 Apr;62(5-6):2040-9. doi: 10.1016/j.neuropharm.2012.01.001. Epub 2012 Jan 10.

11.

Phospholipase C, Ca2+, and calmodulin signaling are required for 5-HT2A receptor-mediated transamidation of Rac1 by transglutaminase.

Dai Y, Dudek NL, Li Q, Muma NA.

Psychopharmacology (Berl). 2011 Feb;213(2-3):403-12. doi: 10.1007/s00213-010-1984-7. Epub 2010 Aug 18.

12.

Transglutaminase activation in neurodegenerative diseases.

Jeitner TM, Muma NA, Battaile KP, Cooper AJ.

Future Neurol. 2009 Jul 1;4(4):449-467.

13.

Estradiol-induced desensitization of 5-HT1A receptor signaling in the paraventricular nucleus of the hypothalamus is independent of estrogen receptor-beta.

Rossi DV, Dai Y, Thomas P, Carrasco GA, DonCarlos LL, Muma NA, Li Q.

Psychoneuroendocrinology. 2010 Aug;35(7):1023-33. doi: 10.1016/j.psyneuen.2010.01.003. Epub 2010 Feb 6.

14.

Striatal expression of a calmodulin fragment improved motor function, weight loss, and neuropathology in the R6/2 mouse model of Huntington's disease.

Dai Y, Dudek NL, Li Q, Fowler SC, Muma NA.

J Neurosci. 2009 Sep 16;29(37):11550-9. doi: 10.1523/JNEUROSCI.3307-09.2009.

15.

Neuroprotective effects of calmodulin peptide 76-121aa: disruption of calmodulin binding to mutant huntingtin.

Dudek NL, Dai Y, Muma NA.

Brain Pathol. 2010 Jan;20(1):176-89. doi: 10.1111/j.1750-3639.2008.00258.x. Epub 2009 Mar 10.

16.
17.

Extra-nuclear estrogen receptor GPR30 regulates serotonin function in rat hypothalamus.

Xu H, Qin S, Carrasco GA, Dai Y, Filardo EJ, Prossnitz ER, Battaglia G, Doncarlos LL, Muma NA.

Neuroscience. 2009 Feb 18;158(4):1599-607. doi: 10.1016/j.neuroscience.2008.11.028. Epub 2008 Nov 21.

18.

Activation of the JAK-STAT pathway is necessary for desensitization of 5-HT2A receptor-stimulated phospholipase C signalling by olanzapine, clozapine and MDL 100907.

Singh RK, Dai Y, Staudinger JL, Muma NA.

Int J Neuropsychopharmacol. 2009 Jun;12(5):651-65. doi: 10.1017/S1461145708009590. Epub 2008 Oct 31.

19.

Sustained treatment with a 5-HT(2A) receptor agonist causes functional desensitization and reductions in agonist-labeled 5-HT(2A) receptors despite increases in receptor protein levels in rats.

Shi J, Landry M, Carrasco GA, Battaglia G, Muma NA.

Neuropharmacology. 2008 Oct;55(5):687-92. doi: 10.1016/j.neuropharm.2008.06.001. Epub 2008 Jun 7.

20.

Transglutaminase-catalyzed transamidation: a novel mechanism for Rac1 activation by 5-hydroxytryptamine2A receptor stimulation.

Dai Y, Dudek NL, Patel TB, Muma NA.

J Pharmacol Exp Ther. 2008 Jul;326(1):153-62. doi: 10.1124/jpet.107.135046. Epub 2008 Apr 9.

21.

Protective effects of interrupting the binding of calmodulin to mutant huntingtin.

Dudek NL, Dai Y, Muma NA.

J Neuropathol Exp Neurol. 2008 Apr;67(4):355-65. doi: 10.1097/NEN.0b013e31816a9e60.

PMID:
18379433
22.

5-HT1A receptors mediate (+)8-OH-DPAT-stimulation of extracellular signal-regulated kinase (MAP kinase) in vivo in rat hypothalamus: time dependence and regional differences.

Crane JW, Shimizu K, Carrasco GA, Garcia F, Jia C, Sullivan NR, D'Souza DN, Zhang Y, Van de Kar LD, Muma NA, Battaglia G.

Brain Res. 2007 Dec 5;1183:51-9. Epub 2007 Sep 29.

PMID:
17976547
23.

Chronic olanzapine activates the Stat3 signal transduction pathway and alters expression of components of the 5-HT2A receptor signaling system in rat frontal cortex.

Muma NA, Singh RK, Vercillo MS, D'Souza DN, Zemaitaitis B, Garcia F, Damjanoska KJ, Zhang Y, Battaglia G, Van de Kar LD.

Neuropharmacology. 2007 Sep;53(4):552-62. Epub 2007 Jul 1.

24.

Agonist induced-phosphorylation of Galpha11 protein reduces coupling to 5-HT2A receptors.

Shi J, Damjanoska KJ, Singh RK, Carrasco GA, Garcia F, Grippo AJ, Landry M, Sullivan NR, Battaglia G, Muma NA.

J Pharmacol Exp Ther. 2007 Oct;323(1):248-56. Epub 2007 Jul 23.

PMID:
17646429
25.

Transglutaminase is linked to neurodegenerative diseases.

Muma NA.

J Neuropathol Exp Neurol. 2007 Apr;66(4):258-63. Review.

PMID:
17413316
26.

Olanzapine increases RGS7 protein expression via stimulation of the Janus tyrosine kinase-signal transducer and activator of transcription signaling cascade.

Singh RK, Shi J, Zemaitaitis BW, Muma NA.

J Pharmacol Exp Ther. 2007 Jul;322(1):133-40. Epub 2007 Mar 28.

PMID:
17392403
27.

Single exposure to a serotonin 1A receptor agonist, (+)8-hydroxy-2-(di-n-propylamino)-tetralin, produces a prolonged heterologous desensitization of serotonin 2A receptors in neuroendocrine neurons in vivo.

Carrasco GA, Van de Kar LD, Jia C, Xu H, Chen Z, Chadda R, Garcia F, Muma NA, Battaglia G.

J Pharmacol Exp Ther. 2007 Mar;320(3):1078-86. Epub 2006 Dec 11.

PMID:
17159160
28.

Phosphorylation of Galpha11 protein contributes to agonist-induced desensitization of 5-HT2A receptor signaling.

Shi J, Zemaitaitis B, Muma NA.

Mol Pharmacol. 2007 Jan;71(1):303-13. Epub 2006 Oct 20.

PMID:
17056873
29.

Cocaine-mediated supersensitivity of 5-HT2A receptors in hypothalamic paraventricular nucleus is a withdrawal-induced phenomenon.

Carrasco GA, Van de Kar LD, Sullivan NR, Landry M, Garcia F, Muma NA, Battaglia G.

Neuroscience. 2006 Nov 17;143(1):7-13. Epub 2006 Oct 19.

30.

Alterations in 5-HT2A receptor signaling in male and female transgenic rats over-expressing either Gq or RGS-insensitive Gq protein.

Shi J, Damjanoska KJ, Zemaitaitis B, Garcia F, Carrasco G, Sullivan NR, She Y, Young KH, Battaglia G, Van De kar LD, Howland DS, Muma NA.

Neuropharmacology. 2006 Sep;51(3):524-35.

PMID:
16769091
31.

Paroxetine is effective in desensitizing 5-HT1A receptor function in adult offspring exposed prenatally to cocaine.

Chen Z, Tetzlaff J, Sripathirathan K, Carrasco GA, Shankaran M, Van De Kar LD, Muma NA, Battaglia G.

Psychopharmacology (Berl). 2005 Jul;180(2):316-26. Epub 2005 Apr 28.

PMID:
15864558
32.

Mutant huntingtin protein: a substrate for transglutaminase 1, 2, and 3.

Zainelli GM, Dudek NL, Ross CA, Kim SY, Muma NA.

J Neuropathol Exp Neurol. 2005 Jan;64(1):58-65.

PMID:
15715085
33.

Tau protein is cross-linked by transglutaminase in P301L tau transgenic mice.

Halverson RA, Lewis J, Frausto S, Hutton M, Muma NA.

J Neurosci. 2005 Feb 2;25(5):1226-33.

34.

Chronic mild stress induces behavioral and physiological changes, and may alter serotonin 1A receptor function, in male and cycling female rats.

Grippo AJ, Sullivan NR, Damjanoska KJ, Crane JW, Carrasco GA, Shi J, Chen Z, Garcia F, Muma NA, Van de Kar LD.

Psychopharmacology (Berl). 2005 Jun;179(4):769-80. Epub 2004 Dec 24.

PMID:
15619113
35.

Estrogen reduces serotonin-1A receptor-mediated oxytocin release and Galpha(i/o/z) proteins in the hypothalamus of ovariectomized rats.

D'Souza DN, Zhang Y, Damjanoska KJ, Carrasco GA, Sullivan NR, Garcia F, Battaglia G, Doncarlos LL, Muma NA, Van de Kar LD.

Neuroendocrinology. 2004;80(1):31-41.

PMID:
15385710
36.

Estrogen treatment increases the levels of regulator of G protein signaling-Z1 in the hypothalamic paraventricular nucleus: possible role in desensitization of 5-hydroxytryptamine1A receptors.

Carrasco GA, Barker SA, Zhang Y, Damjanoska KJ, Sullivan NR, Garcia F, D'souza DN, Muma NA, van De Kar LD.

Neuroscience. 2004;127(2):261-7.

PMID:
15262317
37.

Short-term cocaine treatment causes neuroadaptive changes in Galphaq and Galpha11 proteins in rats undergoing withdrawal.

Carrasco GA, Damjanoska KJ, D'Souza DN, Zhang Y, Garcia F, Battaglia G, Muma NA, Van de Kar LD.

J Pharmacol Exp Ther. 2004 Oct;311(1):349-55. Epub 2004 Jun 2.

PMID:
15175423
38.

Desensitization of 5-HT1A receptors by 5-HT2A receptors in neuroendocrine neurons in vivo.

Zhang Y, Gray TS, D'Souza DN, Carrasco GA, Damjanoska KJ, Dudas B, Garcia F, Zainelli GM, Sullivan Hanley NR, Battaglia G, Muma NA, Van de Kar LD.

J Pharmacol Exp Ther. 2004 Jul;310(1):59-66. Epub 2004 Apr 2.

PMID:
15064330
39.

Calmodulin regulates transglutaminase 2 cross-linking of huntingtin.

Zainelli GM, Ross CA, Troncoso JC, Fitzgerald JK, Muma NA.

J Neurosci. 2004 Feb 25;24(8):1954-61.

40.

Agonist-induced serotonin 2A receptor desensitization in the rat frontal cortex and hypothalamus.

Damjanoska KJ, Heidenreich BA, Kindel GH, D'Souza DN, Zhang Y, Garcia F, Battaglia G, Wolf WA, Van de Kar LD, Muma NA.

J Pharmacol Exp Ther. 2004 Jun;309(3):1043-50. Epub 2004 Feb 19.

PMID:
14976228
41.

A region-specific increase in Galphaq and Galpha11 proteins in brains of rats during cocaine withdrawal.

Carrasco GA, Zhang Y, Damjanoska KJ, D'Souza DN, Garcia F, Battaglia G, Muma NA, Van de Kar LD.

J Pharmacol Exp Ther. 2003 Dec;307(3):1012-9. Epub 2003 Oct 8.

PMID:
14534355
42.

Chronic fluoxetine differentially affects 5-hydroxytryptamine (2A) receptor signaling in frontal cortex, oxytocin- and corticotropin-releasing factor-containing neurons in rat paraventricular nucleus.

Damjanoska KJ, Van de Kar LD, Kindel GH, Zhang Y, D'Souza DN, Garcia F, Battaglia G, Muma NA.

J Pharmacol Exp Ther. 2003 Aug;306(2):563-71. Epub 2003 Apr 29.

PMID:
12721328
43.

Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol- l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine(2C) receptor agonist.

Damjanoska KJ, Muma NA, Zhang Y, D'Souza DN, Garcia F, Carrasco GA, Kindel GH, Haskins KA, Shankaran M, Petersen BR, Van De Kar LD.

J Pharmacol Exp Ther. 2003 Mar;304(3):1209-16.

PMID:
12604698
44.

Transglutaminase activity, protein, and mRNA expression are increased in progressive supranuclear palsy.

Zemaitaitis MO, Kim SY, Halverson RA, Troncoso JC, Lee JM, Muma NA.

J Neuropathol Exp Neurol. 2003 Feb;62(2):173-84.

PMID:
12578227
45.

Ovariectomy-induced increases in hypothalamic serotonin-1A receptor function in rats are prevented by estradiol.

Raap DK, DonCarlos LL, Garcia F, Zhang Y, Muma NA, Battaglia G, Van de Kar LD.

Neuroendocrinology. 2002 Dec;76(6):348-56.

PMID:
12566942
46.

Transglutaminase cross-links in intranuclear inclusions in Huntington disease.

Zainelli GM, Ross CA, Troncoso JC, Muma NA.

J Neuropathol Exp Neurol. 2003 Jan;62(1):14-24.

PMID:
12528814
48.

Evidence that 5-HT2A receptors in the hypothalamic paraventricular nucleus mediate neuroendocrine responses to (-)DOI.

Zhang Y, Damjanoska KJ, Carrasco GA, Dudas B, D'Souza DN, Tetzlaff J, Garcia F, Hanley NR, Scripathirathan K, Petersen BR, Gray TS, Battaglia G, Muma NA, Van de Kar LD.

J Neurosci. 2002 Nov 1;22(21):9635-42.

49.

An R5L tau mutation in a subject with a progressive supranuclear palsy phenotype.

Poorkaj P, Muma NA, Zhukareva V, Cochran EJ, Shannon KM, Hurtig H, Koller WC, Bird TD, Trojanowski JQ, Lee VM, Schellenberg GD.

Ann Neurol. 2002 Oct;52(4):511-6.

PMID:
12325083
50.

Treatment of cycling female rats with fluoxetine induces desensitization of hypothalamic 5-HT(1A) receptors with no change in 5-HT(2A) receptors.

Van de Kar LD, Raap DK, Battaglia G, Muma NA, Garcia F, DonCarlos LL.

Neuropharmacology. 2002 Jul;43(1):45-54.

PMID:
12213258

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