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Genomic Epidemiology of Major Extraintestinal Pathogenic Escherichia coli Lineages Causing Urinary Tract Infections in Young Women Across Canada.

Fibke CD, Croxen MA, Geum HM, Glass M, Wong E, Avery BP, Daignault D, Mulvey MR, Reid-Smith RJ, Parmley EJ, Portt A, Boerlin P, Manges AR.

Open Forum Infect Dis. 2019 Oct 9;6(11):ofz431. doi: 10.1093/ofid/ofz431. eCollection 2019 Nov.


An exploratory randomized-controlled trial of the efficacy of the Src-kinase inhibitor saracatinib as a novel analgesic for cancer-induced bone pain.

Danson S, Mulvey MR, Turner L, Horsman J, Escott K, Coleman RE, Ahmedzai SH, Bennett MI, Andrew D.

J Bone Oncol. 2019 Sep 18;19:100261. doi: 10.1016/j.jbo.2019.100261. eCollection 2019 Dec.


Trends in antimicrobial resistance over 10 years among key bacterial pathogens from Canadian hospitals: results of the CANWARD study 2007-16.

Lagacé-Wiens PRS, Adam HJ, Poutanen S, Baxter MR, Denisuik AJ, Golden AR, Nichol KA, Walkty A, Karlowsky JA, Mulvey MR, Golding G, Hoban DJ, Zhanel GG; Canadian Antimicrobial Resistance Alliance (CARA) and CANWARD .

J Antimicrob Chemother. 2019 Aug 1;74(Supplement_4):iv22-iv31. doi: 10.1093/jac/dkz284.


Dramatic rise in the proportion of ESBL-producing Escherichia coli and Klebsiella pneumoniae among clinical isolates identified in Canadian hospital laboratories from 2007 to 2016.

Denisuik AJ, Karlowsky JA, Adam HJ, Baxter MR, Lagacé-Wiens PRS, Mulvey MR, Hoban DJ, Zhanel GG; Canadian Antimicrobial Resistance Alliance (CARA) and CANWARD .

J Antimicrob Chemother. 2019 Aug 1;74(Supplement_4):iv64-iv71. doi: 10.1093/jac/dkz289.


Comparison of antimicrobial resistance patterns in Streptococcus pneumoniae from respiratory and blood cultures in Canadian hospitals from 2007-16.

Golden AR, Baxter MR, Davidson RJ, Martin I, Demczuk W, Mulvey MR, Karlowsky JA, Hoban DJ, Zhanel GG, Adam HJ; Canadian Antimicrobial Resistance Alliance (CARA) and CANWARD .

J Antimicrob Chemother. 2019 Aug 1;74(Supplement_4):iv39-iv47. doi: 10.1093/jac/dkz286.


Characterization of carbapenem-resistant and XDR Pseudomonas aeruginosa in Canada: results of the CANWARD 2007-16 study.

McCracken MG, Adam HJ, Blondeau JM, Walkty AJ, Karlowsky JA, Hoban DJ, Zhanel GG, Mulvey MR; Canadian Antimicrobial Resistance Alliance (CARA) and CANWARD .

J Antimicrob Chemother. 2019 Aug 1;74(Supplement_4):iv32-iv38. doi: 10.1093/jac/dkz285.


42936 pathogens from Canadian hospitals: 10 years of results (2007-16) from the CANWARD surveillance study.

Zhanel GG, Adam HJ, Baxter MR, Fuller J, Nichol KA, Denisuik AJ, Golden AR, Hink R, Lagacé-Wiens PRS, Walkty A, Mulvey MR, Schweizer F, Bay D, Hoban DJ, Karlowsky JA; Canadian Antimicrobial Resistance Alliance (CARA) and CANWARD .

J Antimicrob Chemother. 2019 Aug 1;74(Supplement_4):iv5-iv21. doi: 10.1093/jac/dkz283.


Commensal Strains of Neisseria Use DNA to Poison Their Pathogenic Rivals.

Fleming BA, Mulvey MA.

Cell Host Microbe. 2019 Aug 14;26(2):156-158. doi: 10.1016/j.chom.2019.07.014.


Population dynamics of an Escherichia coli ST131 lineage during recurrent urinary tract infection.

Forde BM, Roberts LW, Phan MD, Peters KM, Fleming BA, Russell CW, Lenherr SM, Myers JB, Barker AP, Fisher MA, Chong TM, Yin WF, Chan KG, Schembri MA, Mulvey MA, Beatson SA.

Nat Commun. 2019 Aug 13;10(1):3643. doi: 10.1038/s41467-019-11571-5.


The relationship between regional pain with or without neuropathic symptoms and chronic widespread pain.

McBeth J, Mulvey MR, Rashid A, Anderson J, Druce K.

Pain. 2019 Aug;160(8):1817-1823. doi: 10.1097/j.pain.0000000000001568.


Jekyll and Hyde: Bugs with Double Personalities that Muddle the Distinction between Commensal and Pathogen.

Brannon JR, Mulvey MA.

J Mol Biol. 2019 Jul 26;431(16):2911-2913. doi: 10.1016/j.jmb.2019.06.014. Epub 2019 Jun 18. No abstract available.


The relationship between regional pain with or without neuropathic symptoms and chronic widespread pain.

McBeth J, Mulvey MR, Rashid A, Anderson J, Druce K.

Pain. 2019 Apr 8. doi: 10.1097/j.pain.0000000000001568. [Epub ahead of print]


[Interventions to support self-management in cancer pain].

ElMokhallalati Y, Mulvey MR, Bennett MI.

Schmerz. 2019 Jun;33(3):255-260. doi: 10.1007/s00482-019-0372-4. Review. German. No abstract available.


Genomic Investigation of the Emergence of Invasive Multidrug-Resistant Salmonella enterica Serovar Dublin in Humans and Animals in Canada.

Mangat CS, Bekal S, Avery BP, Côté G, Daignault D, Doualla-Bell F, Finley R, Lefebvre B, Bharat A, Parmley EJ, Reid-Smith RJ, Longtin J, Irwin RJ, Mulvey MR; Canadian Integrated Program for Antimicrobial Resistance Surveillance Public Health Partnership.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00108-19. doi: 10.1128/AAC.00108-19. Print 2019 Jun.


Multidrug-resistant and extensively drug-resistant Neisseria gonorrhoeae in Canada, 2012-2016.

Martin I, Sawatzky P, Allen V, Lefebvre B, Hoang L, Naidu P, Minion J, Van Caeseele P, Haldane D, Gad RR, Zahariadis G, Corriveau A, German G, Tomas K, Mulvey MR.

Can Commun Dis Rep. 2019 Feb 7;45(2-3):45-53. doi: 10.14745/ccdr.v45i23a01. eCollection 2019 Feb 7.


Two Hypervirulent Klebsiella pneumoniae Isolates Producing a bla KPC-2 Carbapenemase from a Canadian Patient.

Mataseje LF, Boyd DA, Mulvey MR, Longtin Y.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00517-19. doi: 10.1128/AAC.00517-19. Print 2019 Jul.


Diversity of CTX-M-positive Escherichia coli recovered from animals in Canada.

Cormier A, Zhang PLC, Chalmers G, Weese JS, Deckert A, Mulvey M, McAllister T, Boerlin P.

Vet Microbiol. 2019 Apr;231:71-75. doi: 10.1016/j.vetmic.2019.02.031. Epub 2019 Feb 23.


Cancer-Related Neuropathic Pain.

Edwards HL, Mulvey MR, Bennett MI.

Cancers (Basel). 2019 Mar 16;11(3). pii: E373. doi: 10.3390/cancers11030373. Review.


Identification of a novel metallo-β-lactamase, CAM-1, in clinical Pseudomonas aeruginosa isolates from Canada.

Boyd DA, Lisboa LF, Rennie R, Zhanel GG, Dingle TC, Mulvey MR.

J Antimicrob Chemother. 2019 Jun 1;74(6):1563-1567. doi: 10.1093/jac/dkz066.


Molecular Basis for the Potent Inhibition of the Emerging Carbapenemase VCC-1 by Avibactam.

Mangat CS, Vadlamani G, Holicek V, Chu M, Larmour VLC, Vocadlo DJ, Mulvey MR, Mark BL.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02112-18. doi: 10.1128/AAC.02112-18. Print 2019 Apr.


Interventions to support self-management in cancer pain.

ElMokhallalati Y, Mulvey MR, Bennett MI.

Pain Rep. 2018 Oct 5;3(6):e690. doi: 10.1097/PR9.0000000000000690. eCollection 2018 Nov. No abstract available.


Frequency of 16S ribosomal RNA methyltransferase detection among Escherichia coli and Klebsiella pneumoniae clinical isolates obtained from patients in Canadian hospitals (CANWARD, 2013-2017).

Walkty A, Karlowsky JA, Baxter MR, Adam HJ, Boyd D, Bharat A, Mulvey MR, Charles M, Bergevin M, Zhanel GG.

Diagn Microbiol Infect Dis. 2019 Jun;94(2):199-201. doi: 10.1016/j.diagmicrobio.2018.12.005. Epub 2018 Dec 14.


Electronic health record cue identifies epilepsy patients at risk for obstructive sleep apnea.

Mulvey MA, Veerapandiyan A, Marks DA, Ming X.

Neurol Clin Pract. 2018 Dec;8(6):468-471. doi: 10.1212/CPJ.0000000000000502.


Antimicrobial-resistant pathogens in Canadian ICUs: results of the CANWARD 2007 to 2016 study.

Denisuik AJ, Garbutt LA, Golden AR, Adam HJ, Baxter M, Nichol KA, Lagacé-Wiens P, Walkty AJ, Karlowsky JA, Hoban DJ, Mulvey MR, Zhanel GG.

J Antimicrob Chemother. 2019 Mar 1;74(3):645-653. doi: 10.1093/jac/dky477.


Investigation of a Carbapenemase-producing Acinetobacter baumannii outbreak using whole genome sequencing versus a standard epidemiologic investigation.

Bogaty C, Mataseje L, Gray A, Lefebvre B, Lévesque S, Mulvey M, Longtin Y.

Antimicrob Resist Infect Control. 2018 Nov 21;7:140. doi: 10.1186/s13756-018-0437-7. eCollection 2018.


Characterization of a colistin-resistant Salmonella enterica 4,[5],12:i:- harbouring mcr-3.2 on a variant IncHI-2 plasmid identified in Canada.

Mulvey MR, Bharat A, Boyd DA, Irwin RJ, Wylie J.

J Med Microbiol. 2018 Dec;67(12):1673-1675. doi: 10.1099/jmm.0.000854. Epub 2018 Oct 23.


Results from the Canadian Nosocomial Infection Surveillance Program for detection of carbapenemase-producing Acinetobacter spp. in Canadian hospitals, 2010-16.

Boyd DA, Mataseje LF, Pelude L, Mitchell R, Bryce E, Roscoe D, Embree J, Katz K, Kibsey P, Lavallee C, Simor AE, Taylor G, Turgeon N, Langley JM, Amaratunga K, Mulvey MR; Canadian Nosocomial Infection Surveillance Program .

J Antimicrob Chemother. 2019 Feb 1;74(2):315-320. doi: 10.1093/jac/dky416.


A repeated cross-sectional study of the epidemiology of Campylobacter and antimicrobial resistant Enterobacteriaceae in free-living Canada geese in Guelph, Ontario, Canada.

Vogt NA, Pearl DL, Taboada EN, Reid-Smith RJ, Mulvey MR, Janecko N, Mutschall SK, Jardine CM.

Zoonoses Public Health. 2019 Feb;66(1):60-72. doi: 10.1111/zph.12529. Epub 2018 Oct 4.


Evaluation of Oxford Nanopore's MinION Sequencing Device for Microbial Whole Genome Sequencing Applications.

Tyler AD, Mataseje L, Urfano CJ, Schmidt L, Antonation KS, Mulvey MR, Corbett CR.

Sci Rep. 2018 Jul 19;8(1):10931. doi: 10.1038/s41598-018-29334-5.


Molecular characterization of predominant Streptococcus pneumoniae serotypes causing invasive infections in Canada: the SAVE study, 2011-15.

Golden AR, Adam HJ, Karlowsky JA, Baxter M, Nichol KA, Martin I, Demczuk W, Van Caeseele P, Gubbay JB, Lefebvre B, Levett PN, Zahariadis G, Haldane D, Gad R, German G, Gilmour MW, Mulvey MR, Hoban DJ, Zhanel GG; Canadian Antimicrobial Resistance Alliance (CARA).

J Antimicrob Chemother. 2018 Jul 1;73(suppl_7):vii20-vii31. doi: 10.1093/jac/dky157.


Analysis of multidrug resistance in the predominant Streptococcus pneumoniae serotypes in Canada: the SAVE study, 2011-15.

Adam HJ, Golden AR, Karlowsky JA, Baxter MR, Nichol KA, Martin I, Demczuk W, Mulvey MR, Gilmour MW, Hoban DJ, Zhanel GG; Canadian Antimicrobial Resistance Alliance (CARA).

J Antimicrob Chemother. 2018 Jul 1;73(suppl_7):vii12-vii19. doi: 10.1093/jac/dky158.


Antimicrobial susceptibility testing of invasive isolates of Streptococcus pneumoniae from Canadian patients: the SAVE study, 2011-15.

Karlowsky JA, Adam HJ, Golden AR, Baxter MR, Nichol KA, Martin I, Demczuk W, Mulvey MR, Gilmour MW, Hoban DJ, Zhanel GG; Canadian Antimicrobial Resistance Alliance (CARA).

J Antimicrob Chemother. 2018 Jul 1;73(suppl_7):vii5-vii11. doi: 10.1093/jac/dky156.


The evolving epidemiology of Clostridium difficile infection in Canadian hospitals during a postepidemic period (2009-2015).

Katz KC, Golding GR, Choi KB, Pelude L, Amaratunga KR, Taljaard M, Alexandre S, Collet JC, Davis I, Du T, Evans GA, Frenette C, Gravel D, Hota S, Kibsey P, Langley JM, Lee BE, Lemieux C, Longtin Y, Mertz D, Mieusement LMD, Minion J, Moore DL, Mulvey MR, Richardson S, Science M, Simor AE, Stagg P, Suh KN, Taylor G, Wong A, Thampi N; Canadian Nosocomial Infection Surveillance Program.

CMAJ. 2018 Jun 25;190(25):E758-E765. doi: 10.1503/cmaj.180013.


Serotype distribution of invasive Streptococcus pneumoniae in adults 65 years of age and over after the introduction of childhood 13-valent pneumococcal conjugate vaccination programs in Canada, 2010-2016.

Demczuk WHB, Martin I, Desai S, Griffith A, Caron-Poulin L, Lefebvre B, McGeer A, Tyrrell GJ, Zhanel GG, Gubbay J, Hoang L, Levett PN, Van Caeseele P, Raafat Gad R, Haldane D, Zahariadis G, German G, Daley Bernier J, Strudwick L, Mulvey MR.

Vaccine. 2018 Jul 25;36(31):4701-4707. doi: 10.1016/j.vaccine.2018.06.018. Epub 2018 Jun 21.


Duration and determinants of hospice-based specialist palliative care: A national retrospective cohort study.

Allsop MJ, Ziegler LE, Mulvey MR, Russell S, Taylor R, Bennett MI.

Palliat Med. 2018 Sep;32(8):1322-1333. doi: 10.1177/0269216318781417. Epub 2018 Jun 6.


Canada-Wide Epidemic of emm74 Group A Streptococcus Invasive Disease.

Teatero S, McGeer A, Tyrrell GJ, Hoang L, Smadi H, Domingo MC, Levett PN, Finkelstein M, Dewar K, Plevneshi A, Athey TBT, Gubbay JB, Mulvey MR, Martin I, Demczuk W, Fittipaldi N.

Open Forum Infect Dis. 2018 Apr 20;5(5):ofy085. doi: 10.1093/ofid/ofy085. eCollection 2018 May.


Canadian recommendations for laboratory interpretation of multiple or extensive drug resistance in clinical isolates of Enterobacteriaceae, Acinetobacter species and Pseudomonas aeruginosa.

German GJ, Gilmour M, Tipples G, Adam HJ, Almohri H, Bullard J, Dingle T, Farrell D, Girouard G, Haldane D, Hoang L, Levett PN, Melano R, Minion J, Needle R, Patel SN, Rennie R, Reyes RC, Longtin J, Mulvey MR.

Can Commun Dis Rep. 2018 Jan 4;44(1):29-34. eCollection 2018 Jan 4.


Utilization of Nucleic Acid Amplification Testing Samples for Antimicrobial Resistance Surveillance in Remote Canadian Communities.

Mulvey MR, Martin I, Wong T.

Sex Transm Dis. 2018 Aug;45(8):e61. doi: 10.1097/OLQ.0000000000000860. No abstract available.


Cooperative Recognition of Internationally Disseminated Ceftriaxone-Resistant Neisseria gonorrhoeae Strain.

Lahra MM, Martin I, Demczuk W, Jennison AV, Lee KI, Nakayama SI, Lefebvre B, Longtin J, Ward A, Mulvey MR, Wi T, Ohnishi M, Whiley D.

Emerg Infect Dis. 2018 Apr;24(4). doi: 10.3201/eid2404.171873.


A critical appraisal of gabapentinoids for pain in cancer patients.

Jordan RI, Mulvey MR, Bennett MI.

Curr Opin Support Palliat Care. 2018 Jun;12(2):108-117. doi: 10.1097/SPC.0000000000000337. Review.


Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics.

MacNair CR, Stokes JM, Carfrae LA, Fiebig-Comyn AA, Coombes BK, Mulvey MR, Brown ED.

Nat Commun. 2018 Jan 31;9(1):458. doi: 10.1038/s41467-018-02875-z.


A Comparison of Real-Time Polymerase Chain Reaction Assays for the Detection of Antimicrobial Resistance Markers and Sequence Typing From Clinical Nucleic Acid Amplification Test Samples and Matched Neisseria gonorrhoeae Culture.

Peterson SW, Martin I, Demczuk W, Hoang L, Wylie J, Lefebvre B, Labbé AC, Naidu P, Haldane D, Mulvey MR.

Sex Transm Dis. 2018 Feb;45(2):92-95. doi: 10.1097/OLQ.0000000000000707.


Context-Dependent Requirements for FimH and Other Canonical Virulence Factors in Gut Colonization by Extraintestinal Pathogenic Escherichia coli.

Russell CW, Fleming BA, Jost CA, Tran A, Stenquist AT, Wambaugh MA, Bronner MP, Mulvey MA.

Infect Immun. 2018 Feb 20;86(3). pii: e00746-17. doi: 10.1128/IAI.00746-17. Print 2018 Mar.


Characterization of OXA-48-like carbapenemase producers in Canada, 2011-14.

Mataseje LF, Boyd DA, Fuller J, Haldane D, Hoang L, Lefebvre B, Melano RG, Poutanen S, Van Caeseele P, Mulvey MR.

J Antimicrob Chemother. 2018 Mar 1;73(3):626-633. doi: 10.1093/jac/dkx462.


Self-management toolkit and delivery strategy for end-of-life pain: the mixed-methods feasibility study.

Bennett MI, Mulvey MR, Campling N, Latter S, Richardson A, Bekker H, Blenkinsopp A, Carder P, Closs J, Farrin A, Flemming K, Gallagher J, Meads D, Morley S, O'Dwyer J, Wright-Hughes A, Hartley S.

Health Technol Assess. 2017 Dec;21(76):1-292. doi: 10.3310/hta21760.


Comparison of sequential multiplex PCR, sequetyping and whole genome sequencing for serotyping of Streptococcus pneumoniae.

Mauffrey F, Fournier É, Demczuk W, Martin I, Mulvey M, Martineau C, Lévesque S, Bekal S, Domingo MC, Doualla-Bell F, Longtin J, Lefebvre B.

PLoS One. 2017 Dec 13;12(12):e0189163. doi: 10.1371/journal.pone.0189163. eCollection 2017.


Risk factors for acquisition of multidrug-resistant Escherichia coli and development of community-acquired urinary tract infections.

Ukah UV, Glass M, Avery B, Daignault D, Mulvey MR, Reid-Smith RJ, Parmley EJ, Portt A, Boerlin P, Manges AR.

Epidemiol Infect. 2018 Jan;146(1):46-57. doi: 10.1017/S0950268817002680. Epub 2017 Dec 12.


Characterising the growth in palliative care prescribing 2011-2015: Analysis of national medical and non-medical activity.

Ziegler L, Bennett MI, Mulvey M, Hamilton T, Blenkinsopp A.

Palliat Med. 2018 Apr;32(4):767-774. doi: 10.1177/0269216317739805. Epub 2017 Nov 13.


Neuropathic pain in cancer: systematic review, performance of screening tools and analysis of symptom profiles.

Mulvey MR, Boland EG, Bouhassira D, Freynhagen R, Hardy J, Hjermstad MJ, Mercadante S, Pérez C, Bennett MI.

Br J Anaesth. 2017 Oct 1;119(4):765-774. doi: 10.1093/bja/aex175.

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