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Items: 1 to 50 of 203

1.

Animal Models of Hypertension: A Scientific Statement From the American Heart Association.

Lerman LO, Kurtz TW, Touyz RM, Ellison DH, Chade AR, Crowley SD, Mattson DL, Mullins JJ, Osborn J, Eirin A, Reckelhoff JF, Iadecola C, Coffman TM.

Hypertension. 2019 Jun;73(6):e87-e120. doi: 10.1161/HYP.0000000000000090.

PMID:
30866654
2.

The Efficacy of Puromycin and Adriamycin for Induction of Glomerular Failure in Larval Zebrafish Validated by an Assay of Glomerular Permeability Dynamics.

Rider SA, Bruton FA, Collins RG, Conway BR, Mullins JJ.

Zebrafish. 2018 Jun;15(3):234-242. doi: 10.1089/zeb.2017.1527. Epub 2018 Feb 26.

3.

mCCDcl1 cells show plasticity consistent with the ability to transition between principal and intercalated cells.

Assmus AM, Mansley MK, Mullins LJ, Peter A, Mullins JJ.

Am J Physiol Renal Physiol. 2018 May 1;314(5):F820-F831. doi: 10.1152/ajprenal.00354.2017. Epub 2017 Dec 20.

4.

Phenotypic dissection of the mouse Ren1d knockout by complementation with human renin.

Buckley C, Nelson RJ, Mullins LJ, Sharp MGF, Fleming S, Kenyon CJ, Semprini S, Steppan D, Peti-Peterdi J, Kurtz A, Christian H, Mullins JJ.

J Biol Chem. 2018 Jan 26;293(4):1151-1162. doi: 10.1074/jbc.RA117.000160. Epub 2017 Nov 9.

5.

Asymmetric BMP4 signalling improves the realism of kidney organoids.

Mills CG, Lawrence ML, Munro DAD, Elhendawi M, Mullins JJ, Davies JA.

Sci Rep. 2017 Nov 1;7(1):14824. doi: 10.1038/s41598-017-14809-8.

6.

Characterization of Triptolide-Induced Hepatotoxicity by Imaging and Transcriptomics in a Novel Zebrafish Model.

Vliegenthart ADB, Wei C, Buckley C, Berends C, de Potter CMJ, Schneemann S, Del Pozo J, Tucker C, Mullins JJ, Webb DJ, Dear JW.

Toxicol Sci. 2017 Oct 1;159(2):380-391. doi: 10.1093/toxsci/kfx144.

7.

Transcription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses.

Menzies RI, Zhao X, Mullins LJ, Mullins JJ, Cairns C, Wrobel N, Dunbar DR, Bailey MA, Kenyon CJ.

Endocr Connect. 2017 Oct;6(7):446-457. doi: 10.1530/EC-17-0092. Epub 2017 Jul 18.

8.

Precise spatio-temporal control of rapid optogenetic cell ablation with mem-KillerRed in Zebrafish.

Buckley C, Carvalho MT, Young LK, Rider SA, McFadden C, Berlage C, Verdon RF, Taylor JM, Girkin JM, Mullins JJ.

Sci Rep. 2017 Jul 11;7(1):5096. doi: 10.1038/s41598-017-05028-2.

9.

Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury.

Menzies RI, Booth JWR, Mullins JJ, Bailey MA, Tam FWK, Norman JT, Unwin RJ.

EBioMedicine. 2017 May;19:73-83. doi: 10.1016/j.ebiom.2017.04.011. Epub 2017 Apr 20.

10.

Rapid Fabrication of Cell-Laden Alginate Hydrogel 3D Structures by Micro Dip-Coating.

Ghanizadeh Tabriz A, Mills CG, Mullins JJ, Davies JA, Shu W.

Front Bioeng Biotechnol. 2017 Feb 24;5:13. doi: 10.3389/fbioe.2017.00013. eCollection 2017.

11.

Zebrafish mesonephric renin cells are functionally conserved and comprise two distinct morphological populations.

Rider SA, Christian HC, Mullins LJ, Howarth AR, MacRae CA, Mullins JJ.

Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F778-F790. doi: 10.1152/ajprenal.00608.2016. Epub 2017 Feb 8.

12.

Bimodal dynamics of granular organelles in primary renin-expressing cells revealed using TIRF microscopy.

Buckley C, Dun AR, Peter A, Bellamy C, Gross KW, Duncan RR, Mullins JJ.

Am J Physiol Renal Physiol. 2017 Jan 1;312(1):F200-F209. doi: 10.1152/ajprenal.00384.2016. Epub 2016 Nov 9.

13.

Renal disease pathophysiology and treatment: contributions from the rat.

Mullins LJ, Conway BR, Menzies RI, Denby L, Mullins JJ.

Dis Model Mech. 2016 Dec 1;9(12):1419-1433. Review.

14.

Copper Catalysis in Living Systems and In Situ Drug Synthesis.

Clavadetscher J, Hoffmann S, Lilienkampf A, Mackay L, Yusop RM, Rider SA, Mullins JJ, Bradley M.

Angew Chem Int Ed Engl. 2016 Dec 12;55(50):15662-15666. doi: 10.1002/anie.201609837. Epub 2016 Nov 15.

PMID:
27860120
15.

Effects of Cyclin Dependent Kinase 9 inhibition on zebrafish larvae.

Matrone G, Mullins JJ, Tucker CS, Denvir MA.

Cell Cycle. 2016 Nov 16;15(22):3060-3069. Epub 2016 Oct 7.

16.

Human kidney pericytes produce renin.

Stefanska A, Kenyon C, Christian HC, Buckley C, Shaw I, Mullins JJ, Péault B.

Kidney Int. 2016 Dec;90(6):1251-1261. doi: 10.1016/j.kint.2016.07.035. Epub 2016 Sep 24.

17.

Urinary peptidomics in a rodent model of diabetic nephropathy highlights epidermal growth factor as a biomarker for renal deterioration in patients with type 2 diabetes.

Betz BB, Jenks SJ, Cronshaw AD, Lamont DJ, Cairns C, Manning JR, Goddard J, Webb DJ, Mullins JJ, Hughes J, McLachlan S, Strachan MWJ, Price JF, Conway BR.

Kidney Int. 2016 May;89(5):1125-1135. doi: 10.1016/j.kint.2016.01.015. Epub 2016 Mar 7.

PMID:
27083286
18.

Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension.

Evans LC, Ivy JR, Wyrwoll C, McNairn JA, Menzies RI, Christensen TH, Al-Dujaili EA, Kenyon CJ, Mullins JJ, Seckl JR, Holmes MC, Bailey MA.

Circulation. 2016 Apr 5;133(14):1360-70. doi: 10.1161/CIRCULATIONAHA.115.019341. Epub 2016 Mar 7.

19.

ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice.

Jones FE, Bailey MA, Murray LS, Lu Y, McNeilly S, Schlötzer-Schrehardt U, Lennon R, Sado Y, Brownstein DG, Mullins JJ, Kadler KE, Van Agtmael T.

Dis Model Mech. 2016 Feb;9(2):165-76. doi: 10.1242/dmm.021741.

20.

Spatially coordinated dynamic gene transcription in living pituitary tissue.

Featherstone K, Hey K, Momiji H, McNamara AV, Patist AL, Woodburn J, Spiller DG, Christian HC, McNeilly AS, Mullins JJ, Finkenstädt BF, Rand DA, White MR, Davis JR.

Elife. 2016 Feb 1;5:e08494. doi: 10.7554/eLife.08494.

21.

Role of Estrogen Response Element in the Human Prolactin Gene: Transcriptional Response and Timing.

McNamara AV, Adamson AD, Dunham LS, Semprini S, Spiller DG, McNeilly AS, Mullins JJ, Davis JR, White MR.

Mol Endocrinol. 2016 Feb;30(2):189-200. doi: 10.1210/me.2015-1186. Epub 2015 Dec 21.

22.

CDK9 and its repressor LARP7 modulate cardiomyocyte proliferation and response to injury in the zebrafish heart.

Matrone G, Wilson KS, Maqsood S, Mullins JJ, Tucker CS, Denvir MA.

J Cell Sci. 2015 Dec 15;128(24):4560-71. doi: 10.1242/jcs.175018. Epub 2015 Nov 5.

23.

Mineralocorticoid excess or glucocorticoid insufficiency: renal and metabolic phenotypes in a rat Hsd11b2 knockout model.

Mullins LJ, Kenyon CJ, Bailey MA, Conway BR, Diaz ME, Mullins JJ.

Hypertension. 2015 Sep;66(3):e20. doi: 10.1161/HYP.0000000000000035. No abstract available.

PMID:
26269656
24.

Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart.

Wilson KS, Baily J, Tucker CS, Matrone G, Vass S, Moran C, Chapman KE, Mullins JJ, Kenyon C, Hadoke PW, Denvir MA.

Mol Cell Endocrinol. 2015 Oct 15;414:120-31. doi: 10.1016/j.mce.2015.07.025. Epub 2015 Jul 26.

25.

Renin expression in developing zebrafish is associated with angiogenesis and requires the Notch pathway and endothelium.

Rider SA, Mullins LJ, Verdon RF, MacRae CA, Mullins JJ.

Am J Physiol Renal Physiol. 2015 Sep 15;309(6):F531-9. doi: 10.1152/ajprenal.00247.2015. Epub 2015 Jul 22.

26.

Inhibition of the purinergic P2X7 receptor improves renal perfusion in angiotensin-II-infused rats.

Menzies RI, Howarth AR, Unwin RJ, Tam FW, Mullins JJ, Bailey MA.

Kidney Int. 2015 Nov;88(5):1079-87. doi: 10.1038/ki.2015.182. Epub 2015 Jun 24.

27.

Temporal cohesion of the structural, functional and molecular characteristics of the developing zebrafish heart.

Matrone G, Wilson KS, Mullins JJ, Tucker CS, Denvir MA.

Differentiation. 2015 Jun;89(5):117-27. doi: 10.1016/j.diff.2015.05.001. Epub 2015 Jun 19.

28.

Mineralocorticoid Excess or Glucocorticoid Insufficiency: Renal and Metabolic Phenotypes in a Rat Hsd11b2 Knockout Model.

Mullins LJ, Kenyon CJ, Bailey MA, Conway BR, Diaz ME, Mullins JJ.

Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15. Erratum in: Hypertension. 2015 Sep;66(3):e20.

29.

Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats.

Holland PR, Pannozzo MA, Bastin ME, McNeilly AD, Ferguson KJ, Caughey S, Jansen MA, Merrifield GD, Marshall I, Mullins JJ, Wardlaw JM, Sutherland C, Horsburgh K.

J Cereb Blood Flow Metab. 2015 Feb;35(2):188-92. doi: 10.1038/jcbfm.2014.201. Epub 2014 Nov 19.

30.

Hypertrophy in the Distal Convoluted Tubule of an 11β-Hydroxysteroid Dehydrogenase Type 2 Knockout Model.

Hunter RW, Ivy JR, Flatman PW, Kenyon CJ, Craigie E, Mullins LJ, Bailey MA, Mullins JJ.

J Am Soc Nephrol. 2015 Jul;26(7):1537-48. doi: 10.1681/ASN.2013060634. Epub 2014 Oct 27.

31.

Targeted laser ablation of the zebrafish larval heart induces models of heart block, valvular regurgitation, and outflow tract obstruction.

Matrone G, Maqsood S, Taylor J, Mullins JJ, Tucker CS, Denvir MA.

Zebrafish. 2014 Dec;11(6):536-41. doi: 10.1089/zeb.2014.1027.

32.

Tight blood glycaemic and blood pressure control in experimental diabetic nephropathy reduces extracellular matrix production without regression of fibrosis.

Conway BR, Betz B, Sheldrake TA, Manning JR, Dunbar DR, Dobyns A, Hughes J, Mullins JJ.

Nephrology (Carlton). 2014 Dec;19(12):802-13. doi: 10.1111/nep.12335.

33.

Heart on a plate: histological and functional assessment of isolated adult zebrafish hearts maintained in culture.

Pieperhoff S, Wilson KS, Baily J, de Mora K, Maqsood S, Vass S, Taylor J, Del-Pozo J, MacRae CA, Mullins JJ, Denvir MA.

PLoS One. 2014 May 13;9(5):e96771. doi: 10.1371/journal.pone.0096771. eCollection 2014.

34.

Acute inhibition of NCC does not activate distal electrogenic Na+ reabsorption or kaliuresis.

Hunter RW, Craigie E, Homer NZ, Mullins JJ, Bailey MA.

Am J Physiol Renal Physiol. 2014 Feb 15;306(4):F457-67. doi: 10.1152/ajprenal.00339.2013. Epub 2014 Jan 8.

35.

Effect of P2X4 and P2X7 receptor antagonism on the pressure diuresis relationship in rats.

Menzies RI, Unwin RJ, Dash RK, Beard DA, Cowley AW Jr, Carlson BE, Mullins JJ, Bailey MA.

Front Physiol. 2013 Oct 25;4:305. doi: 10.3389/fphys.2013.00305. eCollection 2013.

36.

Physiological roles of glucocorticoids during early embryonic development of the zebrafish (Danio rerio).

Wilson KS, Matrone G, Livingstone DE, Al-Dujaili EA, Mullins JJ, Tucker CS, Hadoke PW, Kenyon CJ, Denvir MA.

J Physiol. 2013 Dec 15;591(24):6209-20. doi: 10.1113/jphysiol.2013.256826. Epub 2013 Oct 28.

37.

Controlled hypertension induces cerebrovascular and gene alterations in Cyp1a1-Ren2 transgenic rats.

Pannozzo MA, Holland PR, Scullion G, Talbot R, Mullins JJ, Horsburgh K.

J Am Soc Hypertens. 2013 Nov-Dec;7(6):411-9. doi: 10.1016/j.jash.2013.07.011. Epub 2013 Oct 8.

PMID:
24119481
38.

Laser-targeted ablation of the zebrafish embryonic ventricle: a novel model of cardiac injury and repair.

Matrone G, Taylor JM, Wilson KS, Baily J, Love GD, Girkin JM, Mullins JJ, Tucker CS, Denvir MA.

Int J Cardiol. 2013 Oct 9;168(4):3913-9. doi: 10.1016/j.ijcard.2013.06.063. Epub 2013 Jul 18.

39.

An anatomically unbiased approach for analysis of renal BOLD magnetic resonance images.

Menzies RI, Zammit-Mangion A, Hollis LM, Lennen RJ, Jansen MA, Webb DJ, Mullins JJ, Dear JW, Sanguinetti G, Bailey MA.

Am J Physiol Renal Physiol. 2013 Sep 15;305(6):F845-52. doi: 10.1152/ajprenal.00113.2013. Epub 2013 Jul 17.

40.

Renal pericytes: multifunctional cells of the kidneys.

Stefańska A, Péault B, Mullins JJ.

Pflugers Arch. 2013 Jun;465(6):767-73. doi: 10.1007/s00424-013-1263-7. Epub 2013 Apr 16. Review. Erratum in: Pflugers Arch. 2013 Jun;465(6):919. Stefańska, A M [corrected to Stefańska, Ania]; Péault, B [corrected to Péault, Bruno]; Mullins, J J [corrected to Mullins, John J].

PMID:
23588377
41.

Irreversible renal damage after transient renin-angiotensin system stimulation: involvement of an AT1-receptor mediated immune response.

Heijnen BF, Nelissen J, van Essen H, Fazzi GE, Cohen Tervaert JW, Peutz-Kootstra CJ, Mullins JJ, Schalkwijk CG, Janssen BJ, Struijker-Boudier HA.

PLoS One. 2013;8(2):e57815. doi: 10.1371/journal.pone.0057815. Epub 2013 Feb 28.

42.

Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats.

Heijnen BF, Pelkmans LP, Danser AH, Garrelds IM, Mullins JJ, De Mey JG, Struijker-Boudier HA, Janssen BJ.

J Renin Angiotensin Aldosterone Syst. 2014 Mar;15(1):69-81. doi: 10.1177/1470320313480537. Epub 2013 Mar 5.

PMID:
23462119
43.

Use of fiber optic technology to measure the effects of anesthesia on luciferase reaction kinetics.

Semprini S, Saunter CD, Ludwig M, Girkin JM, Mullins JJ.

J Am Assoc Lab Anim Sci. 2012 Nov;51(6):820-4.

44.

Failure to downregulate the epithelial sodium channel causes salt sensitivity in Hsd11b2 heterozygote mice.

Craigie E, Evans LC, Mullins JJ, Bailey MA.

Hypertension. 2012 Sep;60(3):684-90. doi: 10.1161/HYPERTENSIONAHA.112.196410. Epub 2012 Jul 9.

45.

A urine-concentrating defect in 11β-hydroxysteroid dehydrogenase type 2 null mice.

Evans LC, Livingstone DE, Kenyon CJ, Jansen MA, Dear JW, Mullins JJ, Bailey MA.

Am J Physiol Renal Physiol. 2012 Aug 15;303(4):F494-502. doi: 10.1152/ajprenal.00165.2012. Epub 2012 May 23.

46.

Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat.

Ashek A, Menzies RI, Mullins LJ, Bellamy CO, Harmar AJ, Kenyon CJ, Flatman PW, Mullins JJ, Bailey MA.

PLoS One. 2012;7(4):e36311. doi: 10.1371/journal.pone.0036311. Epub 2012 Apr 27.

47.

Regression of cardiac hypertrophy in cyp1a1ren-2 transgenic rats.

Peters BS, Dornaika R, Hosten N, Hadlich S, Mullins JJ, Peters J, Rettig R.

J Magn Reson Imaging. 2012 Aug;36(2):373-8. doi: 10.1002/jmri.23661. Epub 2012 Apr 19.

PMID:
22517449
48.

Peritonitis activates transcription of the human prolactin locus in myeloid cells in a humanized transgenic rat model.

Semprini S, McNamara AV, Awais R, Featherstone K, Harper CV, McNeilly JR, Patist A, Rossi AG, Dransfield I, McNeilly AS, Davis JR, White MR, Mullins JJ.

Endocrinology. 2012 Jun;153(6):2724-34. doi: 10.1210/en.2011-1926. Epub 2012 Apr 11.

PMID:
22495675
49.

Techniques for the in vivo assessment of cardio-renal function in zebrafish (Danio rerio) larvae.

Rider SA, Tucker CS, del-Pozo J, Rose KN, MacRae CA, Bailey MA, Mullins JJ.

J Physiol. 2012 Apr 15;590(8):1803-9. doi: 10.1113/jphysiol.2011.224352. Epub 2012 Feb 13.

50.

Optimal elevation of β-cell 11β-hydroxysteroid dehydrogenase type 1 is a compensatory mechanism that prevents high-fat diet-induced β-cell failure.

Turban S, Liu X, Ramage L, Webster SP, Walker BR, Dunbar DR, Mullins JJ, Seckl JR, Morton NM.

Diabetes. 2012 Mar;61(3):642-52. doi: 10.2337/db11-1054. Epub 2012 Feb 7.

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