Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 109

1.

Intestinal barrier tightening by a cell-penetrating antibody to Bin1, a candidate target for immunotherapy of ulcerative colitis.

Thomas S, Hoxha K, Alexander W, Gilligan J, Dilbarova R, Whittaker K, Kossenkov A, Prendergast GC, Mullin JM.

J Cell Biochem. 2018 Sep 30. doi: 10.1002/jcb.27716. [Epub ahead of print]

PMID:
30269357
2.

Accuracy of phase-contrast velocimetry in systems with skewed intravoxel velocity distributions.

Vallatos A, Al-Mubarak HFI, Mullin JM, Holmes WM.

J Magn Reson. 2018 Nov;296:121-129. doi: 10.1016/j.jmr.2018.09.002. Epub 2018 Sep 5.

PMID:
30245475
3.

Cobalt chloride compromises transepithelial barrier properties of CaCo-2 BBe human gastrointestinal epithelial cell layers.

DiGuilio KM, Valenzano MC, Rybakovsky E, Mullin JM.

BMC Gastroenterol. 2018 Jan 5;18(1):2. doi: 10.1186/s12876-017-0731-5.

4.

Improvement of Human-Oral-Epithelial-Barrier Function and of Tight Junctions by Micronutrients.

Rybakovsky E, Valenzano MC, Deis R, DiGuilio KM, Thomas S, Mullin JM.

J Agric Food Chem. 2017 Dec 20;65(50):10950-10958. doi: 10.1021/acs.jafc.7b04203. Epub 2017 Dec 7.

PMID:
29172516
5.

The Host Microbiome Regulates and Maintains Human Health: A Primer and Perspective for Non-Microbiologists.

Thomas S, Izard J, Walsh E, Batich K, Chongsathidkiet P, Clarke G, Sela DA, Muller AJ, Mullin JM, Albert K, Gilligan JP, DiGuilio K, Dilbarova R, Alexander W, Prendergast GC.

Cancer Res. 2017 Apr 15;77(8):1783-1812. doi: 10.1158/0008-5472.CAN-16-2929. Epub 2017 Mar 14. Review.

6.

Zinc reduces epithelial barrier compromise induced by human seminal plasma.

Mullin JM, Diguilio KM, Valenzano MC, Deis R, Thomas S, Zurbach EP, Abdulhaqq S, Montaner LJ.

PLoS One. 2017 Mar 9;12(3):e0170306. doi: 10.1371/journal.pone.0170306. eCollection 2017.

7.

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results.

Margolskee A, Darwich AS, Pepin X, Aarons L, Galetin A, Rostami-Hodjegan A, Carlert S, Hammarberg M, Hilgendorf C, Johansson P, Karlsson E, Murphy D, Tannergren C, Thörn H, Yasin M, Mazuir F, Nicolas O, Ramusovic S, Xu C, Pathak SM, Korjamo T, Laru J, Malkki J, Pappinen S, Tuunainen J, Dressman J, Hansmann S, Kostewicz E, He H, Heimbach T, Wu F, Hoft C, Laplanche L, Pang Y, Bolger MB, Huehn E, Lukacova V, Mullin JM, Szeto KX, Costales C, Lin J, McAllister M, Modi S, Rotter C, Varma M, Wong M, Mitra A, Bevernage J, Biewenga J, Van Peer A, Lloyd R, Shardlow C, Langguth P, Mishenzon I, Nguyen MA, Brown J, Lennernäs H, Abrahamsson B.

Eur J Pharm Sci. 2017 Jan 1;96:610-625. doi: 10.1016/j.ejps.2016.10.036. Epub 2016 Nov 2.

PMID:
27816631
8.

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes.

Darwich AS, Margolskee A, Pepin X, Aarons L, Galetin A, Rostami-Hodjegan A, Carlert S, Hammarberg M, Hilgendorf C, Johansson P, Karlsson E, Murphy D, Tannergren C, Thörn H, Yasin M, Mazuir F, Nicolas O, Ramusovic S, Xu C, Pathak SM, Korjamo T, Laru J, Malkki J, Pappinen S, Tuunainen J, Dressman J, Hansmann S, Kostewicz E, He H, Heimbach T, Wu F, Hoft C, Pang Y, Bolger MB, Huehn E, Lukacova V, Mullin JM, Szeto KX, Costales C, Lin J, McAllister M, Modi S, Rotter C, Varma M, Wong M, Mitra A, Bevernage J, Biewenga J, Van Peer A, Lloyd R, Shardlow C, Langguth P, Mishenzon I, Nguyen MA, Brown J, Lennernäs H, Abrahamsson B.

Eur J Pharm Sci. 2017 Jan 1;96:626-642. doi: 10.1016/j.ejps.2016.09.037. Epub 2016 Sep 28.

PMID:
27693299
9.

Sieving characteristics of cytokine- and peroxide-induced epithelial barrier leak: Inhibition by berberine.

DiGuilio KM, Mercogliano CM, Born J, Ferraro B, To J, Mixson B, Smith A, Valenzano MC, Mullin JM.

World J Gastrointest Pathophysiol. 2016 May 15;7(2):223-34. doi: 10.4291/wjgp.v7.i2.223.

10.

Methionine restriction fundamentally supports health by tightening epithelial barriers.

Mullin JM, Skrovanek SM, Ramalingam A, DiGuilio KM, Valenzano MC.

Ann N Y Acad Sci. 2016 Jan;1363:59-67. doi: 10.1111/nyas.12955. Epub 2015 Dec 8. Review.

PMID:
26646941
11.

Remodeling of Tight Junctions and Enhancement of Barrier Integrity of the CACO-2 Intestinal Epithelial Cell Layer by Micronutrients.

Valenzano MC, DiGuilio K, Mercado J, Teter M, To J, Ferraro B, Mixson B, Manley I, Baker V, Moore BA, Wertheimer J, Mullin JM.

PLoS One. 2015 Jul 30;10(7):e0133926. doi: 10.1371/journal.pone.0133926. eCollection 2015.

12.

Novel Colitis Immunotherapy Targets Bin1 and Improves Colon Cell Barrier Function.

Thomas S, Mercado JM, DuHadaway J, DiGuilio K, Mullin JM, Prendergast GC.

Dig Dis Sci. 2016 Feb;61(2):423-32. doi: 10.1007/s10620-015-3804-8. Epub 2015 Jul 21.

PMID:
26195312
13.

Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.

Pawlikowski JS, Brock C, Chen SC, Al-Olabi L, Nixon C, McGregor F, Paine S, Chanudet E, Lambie W, Holmes WM, Mullin JM, Richmond A, Wu H, Blyth K, King A, Kinsler VA, Adams PD.

J Invest Dermatol. 2015 Nov;135(11):2902. doi: 10.1038/jid.2015.230. Epub 2015 Jul 16. No abstract available.

14.

Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.

Pawlikowski JS, Brock C, Chen SC, Al-Olabi L, Nixon C, McGregor F, Paine S, Chanudet E, Lambie W, Holmes WM, Mullin JM, Richmond A, Wu H, Blyth K, King A, Kinsler VA, Adams PD.

J Invest Dermatol. 2015 Aug;135(8):2093-2101. doi: 10.1038/jid.2015.114. Epub 2015 Mar 27. Erratum in: J Invest Dermatol. 2015 Nov;135(11):2902.

15.

Retrofitting the battlements: tight junction remodeling as a novel antimicrobial approach.

Mullin JM, Raines J, Livornese LL Jr.

Future Med Chem. 2015;7(1):9-13. doi: 10.4155/fmc.14.146. No abstract available.

PMID:
25582329
16.

Zinc and gastrointestinal disease.

Skrovanek S, DiGuilio K, Bailey R, Huntington W, Urbas R, Mayilvaganan B, Mercogliano G, Mullin JM.

World J Gastrointest Pathophysiol. 2014 Nov 15;5(4):496-513. doi: 10.4291/wjgp.v5.i4.496. Review.

17.

Drug delivery of zinc to Barrett's metaplasia by oral administration to Barrett's esophagus patients.

Valenzano MC, Mercado JM, Wang X, Zurbach EP, Raines J, McDonnell E, Morgan M, Farrell C, Rudolph D, Hwang A, Barr M, Cherian D, Bailey R, Raile B, Albert N, Thornton J, Zitin M, Abramson J, Newman G, Daum G, Mercogliano G, Mullin JM.

Ther Deliv. 2014 Mar;5(3):257-64. doi: 10.4155/tde.13.151.

PMID:
24592952
18.

Enhancement of tight junctional barrier function by micronutrients: compound-specific effects on permeability and claudin composition.

Mercado J, Valenzano MC, Jeffers C, Sedlak J, Cugliari MK, Papanikolaou E, Clouse J, Miao J, Wertan NE, Mullin JM.

PLoS One. 2013 Nov 13;8(11):e78775. doi: 10.1371/journal.pone.0078775. eCollection 2013.

19.

Zinc enhancement of LLC-PK(1) renal epithelial barrier function.

Wang X, Valenzano MC, Mercado JM, Zurbach EP, Flounders CJ, Mullin JM.

Clin Nutr. 2014 Apr;33(2):280-6. doi: 10.1016/j.clnu.2013.05.001. Epub 2013 May 7.

PMID:
23755840
20.

Drug interactions produced by proton pump inhibitors: not simply a pH effect.

Mullin JM, Schrogie JJ.

Clin Pharmacol Ther. 2013 Feb;93(2):150. doi: 10.1038/clpt.2012.182. Epub 2012 Nov 21. No abstract available.

PMID:
23169430
21.

Self-assembly and photopolymerization of sub-2 nm one-dimensional organic nanostructures on graphene.

Deshpande A, Sham CH, Alaboson JM, Mullin JM, Schatz GC, Hersam MC.

J Am Chem Soc. 2012 Oct 10;134(40):16759-64. doi: 10.1021/ja307061e. Epub 2012 Sep 7.

PMID:
22928587
22.

Zinc supplementation modifies tight junctions and alters barrier function of CACO-2 human intestinal epithelial layers.

Wang X, Valenzano MC, Mercado JM, Zurbach EP, Mullin JM.

Dig Dis Sci. 2013 Jan;58(1):77-87. doi: 10.1007/s10620-012-2328-8. Epub 2012 Aug 19.

PMID:
22903217
23.

Transepithelial leak in Barrett's esophagus patients: the role of proton pump inhibitors.

Farrell C, Morgan M, Tully O, Wolov K, Kearney K, Ngo B, Mercogliano G, Thornton JJ, Valenzano MC, Mullin JM.

World J Gastroenterol. 2012 Jun 14;18(22):2793-7. doi: 10.3748/wjg.v18.i22.2793.

24.

Bin1 attenuation suppresses experimental colitis by enforcing intestinal barrier function.

Chang MY, Boulden J, Valenzano MC, Soler AP, Muller AJ, Mullin JM, Prendergast GC.

Dig Dis Sci. 2012 Jul;57(7):1813-21. doi: 10.1007/s10620-012-2147-y. Epub 2012 Apr 18.

25.

Proton Pump Inhibitors Interfere With Zinc Absorption and Zinc Body Stores.

Farrell CP, Morgan M, Rudolph DS, Hwang A, Albert NE, Valenzano MC, Wang X, Mercogliano G, Mullin JM.

Gastroenterology Res. 2011 Dec;4(6):243-251. Epub 2011 Nov 20.

26.

Epithelial tight junctional changes in colorectal cancer tissues.

Wang X, Tully O, Ngo B, Zitin M, Mullin JM.

ScientificWorldJournal. 2011 Apr 5;11:826-41. doi: 10.1100/tsw.2011.86. Review.

27.

Tumor necrosis factor blockade for treatment of inflammatory bowel disease: efficacy and safety.

Ngo B, Farrell CP, Barr M, Wolov K, Bailey R, Mullin JM, Thornton JJ.

Curr Mol Pharmacol. 2010 Nov;3(3):145-52. Review.

PMID:
20799925
28.

Dietary methionine restriction improves colon tight junction barrier function and alters claudin expression pattern.

Ramalingam A, Wang X, Gabello M, Valenzano MC, Soler AP, Ko A, Morin PJ, Mullin JM.

Am J Physiol Cell Physiol. 2010 Nov;299(5):C1028-35. doi: 10.1152/ajpcell.00482.2009. Epub 2010 Aug 25.

29.

Na,K-ATPase subunits as markers for epithelial-mesenchymal transition in cancer and fibrosis.

Rajasekaran SA, Huynh TP, Wolle DG, Espineda CE, Inge LJ, Skay A, Lassman C, Nicholas SB, Harper JF, Reeves AE, Ahmed MM, Leatherman JM, Mullin JM, Rajasekaran AK.

Mol Cancer Ther. 2010 Jun;9(6):1515-24. doi: 10.1158/1535-7163.MCT-09-0832. Epub 2010 May 25.

30.

Omeprazole induces gastric transmucosal permeability to the peptide bradykinin.

Gabello M, Valenzano MC, Zurbach EP, Mullin JM.

World J Gastroenterol. 2010 Mar 7;16(9):1097-103.

31.

Water and alanine: from puddles(32) to ponds(49).

Mullin JM, Gordon MS.

J Phys Chem B. 2009 Oct 29;113(43):14413-20. doi: 10.1021/jp904826v.

PMID:
19788284
32.

Systematic fragmentation method and the effective fragment potential: an efficient method for capturing molecular energies.

Mullin JM, Roskop LB, Pruitt SR, Collins MA, Gordon MS.

J Phys Chem A. 2009 Sep 17;113(37):10040-9. doi: 10.1021/jp9036183.

PMID:
19739681
33.

Age-related changes of claudin expression in mouse liver, kidney, and pancreas.

D'Souza T, Sherman-Baust CA, Poosala S, Mullin JM, Morin PJ.

J Gerontol A Biol Sci Med Sci. 2009 Nov;64(11):1146-53. doi: 10.1093/gerona/glp118. Epub 2009 Aug 19.

34.

Modification of tight junction structure and permeability by nutritional means.

Mullin JM, Skrovanek SM, Valenzano MC.

Ann N Y Acad Sci. 2009 May;1165:99-112. doi: 10.1111/j.1749-6632.2009.04028.x.

PMID:
19538294
35.

Omeprazole induces gastric permeability to digoxin.

Gabello M, Valenzano MC, Barr M, Zurbach P, Mullin JM.

Dig Dis Sci. 2010 May;55(5):1255-63. doi: 10.1007/s10620-009-0851-z. Epub 2009 Jun 10.

PMID:
19513837
36.

Alanine: then there was water.

Mullin JM, Gordon MS.

J Phys Chem B. 2009 Jun 25;113(25):8657-69. doi: 10.1021/jp901459y.

PMID:
19485320
37.

Proton pump inhibitors: actions and reactions.

Mullin JM, Gabello M, Murray LJ, Farrell CP, Bellows J, Wolov KR, Kearney KR, Rudolph D, Thornton JJ.

Drug Discov Today. 2009 Jul;14(13-14):647-60. doi: 10.1016/j.drudis.2009.03.014. Epub 2009 Apr 8. Review.

PMID:
19443264
38.

Accurate methods for large molecular systems.

Gordon MS, Mullin JM, Pruitt SR, Roskop LB, Slipchenko LV, Boatz JA.

J Phys Chem B. 2009 Jul 23;113(29):9646-63. doi: 10.1021/jp811519x.

PMID:
19368406
39.

In ovo non-invasive quantification of the myocardial function and mass of chick embryos using magnetic resonance imaging.

Holmes WM, McCabe C, Mullin JM, Condon B, Bain MM.

NMR Biomed. 2009 Aug;22(7):745-52. doi: 10.1002/nbm.1386.

PMID:
19322809
40.

Transmucosal gastric leak induced by proton pump inhibitors.

Murray LJ, Gabello M, Rudolph DS, Farrell CP, Morgan M, Martin AP, Underwood JC, Valenzano MC, Mullin JM.

Dig Dis Sci. 2009 Jul;54(7):1408-17. doi: 10.1007/s10620-008-0528-z. Epub 2008 Nov 18.

PMID:
19015985
41.

Esomeprazole induces upper gastrointestinal tract transmucosal permeability increase.

Mullin JM, Valenzano MC, Whitby M, Lurie D, Schmidt JD, Jain V, Tully O, Kearney K, Lazowick D, Mercogliano G, Thornton JJ.

Aliment Pharmacol Ther. 2008 Dec 1;28(11-12):1317-25. doi: 10.1111/j.1365-2036.2008.03824.x. Epub 2008 Aug 4.

42.

Images in cardiovascular medicine. Noninvasive self-gated magnetic resonance cardiac imaging of developing chick embryos in ovo.

Holmes WM, McCabe C, Mullin JM, Condon B, Bain MM.

Circulation. 2008 May 27;117(21):e346-7. doi: 10.1161/CIRCULATIONAHA.107.747154. No abstract available.

PMID:
18506012
43.

Absence of Na+/sugar cotransport activity in Barrett's metaplasia.

Murray LJ, Tully O, Rudolph DS, Whitby M, Valenzano MC, Mercogliano G, Thornton JJ, Mullin JM.

World J Gastroenterol. 2008 Mar 7;14(9):1365-9.

44.

Serial postmortem relaxometry in the normal rat brain and following stroke.

Fagan AJ, Mullin JM, Gallagher L, Hadley DM, Macrae IM, Condon B.

J Magn Reson Imaging. 2008 Mar;27(3):469-75. doi: 10.1002/jmri.21246.

PMID:
18219613
45.

Measuring quaternary ammonium cleaning agents with ion selective electrodes.

Plesha MA, Van Wie BJ, Mullin JM, Kidwell DA.

Anal Chim Acta. 2006 Jun 16;570(2):186-94. Epub 2006 Jun 2.

PMID:
17723398
46.

Noninvasive monitoring of chick development in ovo using a 7T MRI system from day 12 of incubation through to hatching.

Bain MM, Fagan AJ, Mullin JM, McNaught I, McLean J, Condon B.

J Magn Reson Imaging. 2007 Jul;26(1):198-201.

PMID:
17659540
47.

Restriction of sulfur-containing amino acids alters claudin composition and improves tight junction barrier function.

Skrovanek S, Valenzano MC, Mullin JM.

Am J Physiol Regul Integr Comp Physiol. 2007 Sep;293(3):R1046-55. Epub 2007 Jun 13.

48.

Transepithelial leak in Barrett's esophagus.

Mullin JM, Valenzano MC, Trembeth S, Allegretti PD, Verrecchio JJ, Schmidt JD, Jain V, Meddings JB, Mercogliano G, Thornton JJ.

Dig Dis Sci. 2006 Dec;51(12):2326-36. Epub 2006 Nov 14.

PMID:
17103306
49.

Ras mutation impairs epithelial barrier function to a wide range of nonelectrolytes.

Mullin JM, Leatherman JM, Valenzano MC, Huerta ER, Verrechio J, Smith DM, Snetselaar K, Liu M, Francis MK, Sell C.

Mol Biol Cell. 2005 Dec;16(12):5538-50. Epub 2005 Sep 21.

50.

Occludin: structure, function and regulation.

Feldman GJ, Mullin JM, Ryan MP.

Adv Drug Deliv Rev. 2005 Apr 25;57(6):883-917. Review.

PMID:
15820558

Supplemental Content

Loading ...
Support Center