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Items: 1 to 50 of 176

1.

Proteome-based classification of Nonmuscle Invasive Bladder Cancer.

Stroggilos R, Mokou M, Latosinska A, Makridakis M, Lygirou V, Mavrogeorgis E, Drekolias D, Frantzi M, Mullen W, Fragkoulis C, Stasinopoulos K, Papadopoulos G, Stathouros G, Lazaris AC, Makrythanasis P, Ntoumas K, Mischak H, Zoidakis J, Vlahou A.

Int J Cancer. 2019 Jul 8. doi: 10.1002/ijc.32556. [Epub ahead of print]

PMID:
31286493
2.

Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs.

Pelander L, Brunchault V, Buffin-Meyer B, Klein J, Breuil B, Zürbig P, Magalhães P, Mullen W, Elliott J, Syme H, Schanstra JP, Häggström J, Ljungvall I.

Vet J. 2019 Jul;249:73-79. doi: 10.1016/j.tvjl.2019.05.010. Epub 2019 May 27.

3.

Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment.

Schanstra JP, Luong TT, Makridakis M, Van Linthout S, Lygirou V, Latosinska A, Alesutan I, Boehme B, Schelski N, Von Lewinski D, Mullen W, Nicklin S, Delles C, Feuillet G, Denis C, Lang F, Pieske B, Bascands JL, Mischak H, Saulnier-Blache JS, Voelkl J, Vlahou A, Klein J.

JCI Insight. 2019 May 16;4(10). pii: 125638. doi: 10.1172/jci.insight.125638. eCollection 2019 May 16.

4.

Proteomics based identification of KDM5 histone demethylases associated with cardiovascular disease.

Mokou M, Klein J, Makridakis M, Bitsika V, Bascands JL, Saulnier-Blache JS, Mullen W, Sacherer M, Zoidakis J, Pieske B, Mischak H, Roubelakis MG, Schanstra JP, Vlahou A.

EBioMedicine. 2019 Mar;41:91-104. doi: 10.1016/j.ebiom.2019.02.040. Epub 2019 Feb 28.

5.

Proteomics in Kidney Allograft Transplantation-Application of Molecular Pathway Analysis for Kidney Allograft Disease Phenotypic Biomarker Selection.

Marx D, Metzger J, Olagne J, Belczacka I, Faguer S, Colombat M, Husi H, Mullen W, Gwinner W, Caillard S.

Proteomics Clin Appl. 2019 Mar;13(2):e1800091. doi: 10.1002/prca.201800091. Epub 2019 Feb 4. Review.

PMID:
30680934
6.

Proteomic Evidence of Biological Aging in a Child with a Compound Heterozygous ZMPSTE24 Mutation.

Lucas-Herald AK, Zürbig P, Mason A, Kinning E, Brown CE, Mansoorian B, Mullen W, Ahmed SF, Delles C.

Proteomics Clin Appl. 2019 Mar;13(2):e1800135. doi: 10.1002/prca.201800135. Epub 2018 Dec 27.

7.

Urinary Glycopeptide Analysis for the Investigation of Novel Biomarkers.

Belczacka I, Pejchinovski M, Krochmal M, Magalhães P, Frantzi M, Mullen W, Vlahou A, Mischak H, Jankowski V.

Proteomics Clin Appl. 2019 May;13(3):e1800111. doi: 10.1002/prca.201800111. Epub 2018 Oct 18.

PMID:
30334612
8.

Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost.

Salin K, Villasevil EM, Anderson GJ, Auer SK, Selman C, Hartley RC, Mullen W, Chinopoulos C, Metcalfe NB.

Funct Ecol. 2018 Sep;32(9):2149-2157. doi: 10.1111/1365-2435.13125. Epub 2018 May 29.

9.

Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease.

Lygirou V, Latosinska A, Makridakis M, Mullen W, Delles C, Schanstra JP, Zoidakis J, Pieske B, Mischak H, Vlahou A.

J Transl Med. 2018 Apr 17;16(1):104. doi: 10.1186/s12967-018-1476-9.

10.

Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria.

Currie GE, von Scholten BJ, Mary S, Flores Guerrero JL, Lindhardt M, Reinhard H, Jacobsen PK, Mullen W, Parving HH, Mischak H, Rossing P, Delles C.

Cardiovasc Diabetol. 2018 Apr 6;17(1):50. doi: 10.1186/s12933-018-0697-9.

11.

Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease.

Liu Y, Pejchinovski M, Wang X, Fu X, Castelletti D, Watnick TJ, Arcaro A, Siwy J, Mullen W, Mischak H, Serra AL.

Sci Rep. 2018 Apr 3;8(1):5584. doi: 10.1038/s41598-018-22938-x.

12.

Comparison of Urine and Plasma Peptidome Indicates Selectivity in Renal Peptide Handling.

Magalhães P, Pontillo C, Pejchinovski M, Siwy J, Krochmal M, Makridakis M, Carrick E, Klein J, Mullen W, Jankowski J, Vlahou A, Mischak H, Schanstra JP, Zürbig P, Pape L.

Proteomics Clin Appl. 2018 Sep;12(5):e1700163. doi: 10.1002/prca.201700163. Epub 2018 Apr 23.

PMID:
29611317
13.

Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability.

Williams JJL, Alotaiq N, Mullen W, Burchmore R, Liu L, Baillie GS, Schaper F, Pilch PF, Palmer TM.

Nat Commun. 2018 Jan 12;9(1):168. doi: 10.1038/s41467-017-02585-y.

14.

Association of kidney fibrosis with urinary peptides: a path towards non-invasive liquid biopsies?

Magalhães P, Pejchinovski M, Markoska K, Banasik M, Klinger M, Švec-Billá D, Rychlík I, Rroji M, Restivo A, Capasso G, Bob F, Schiller A, Ortiz A, Perez-Gomez MV, Cannata P, Sanchez-Niño MD, Naumovic R, Brkovic V, Polenakovic M, Mullen W, Vlahou A, Zürbig P, Pape L, Ferrario F, Denis C, Spasovski G, Mischak H, Schanstra JP.

Sci Rep. 2017 Dec 5;7(1):16915. doi: 10.1038/s41598-017-17083-w.

15.

Polyphenols and health: Interactions between fibre, plant polyphenols and the gut microbiota.

Edwards CA, Havlik J, Cong W, Mullen W, Preston T, Morrison DJ, Combet E.

Nutr Bull. 2017 Dec;42(4):356-360. doi: 10.1111/nbu.12296. Epub 2017 Nov 10.

16.

Prediction of Chronic Kidney Disease Stage 3 by CKD273, a Urinary Proteomic Biomarker.

Pontillo C, Zhang ZY, Schanstra JP, Jacobs L, Zürbig P, Thijs L, Ramírez-Torres A, Heerspink HJL, Lindhardt M, Klein R, Orchard T, Porta M, Bilous RW, Charturvedi N, Rossing P, Vlahou A, Schepers E, Glorieux G, Mullen W, Delles C, Verhamme P, Vanholder R, Staessen JA, Mischak H, Jankowski J.

Kidney Int Rep. 2017 Nov;2(6):1066-1075. doi: 10.1016/j.ekir.2017.06.004.

17.

High Resolution Mass Spectrometric Analysis of Secoiridoids and Metabolites as Biomarkers of Acute Olive Oil Intake-An Approach to Study Interindividual Variability in Humans.

Silva S, Garcia-Aloy M, Figueira ME, Combet E, Mullen W, Bronze MR.

Mol Nutr Food Res. 2018 Jan;62(2). doi: 10.1002/mnfr.201700065. Epub 2017 Dec 19.

PMID:
29068138
18.

Comparative proteome and peptidome analysis of the cephalic fluid secreted by Arapaima gigas (Teleostei: Osteoglossidae) during and outside parental care.

Torati LS, Migaud H, Doherty MK, Siwy J, Mullen W, Mesquita PEC, Albalat A.

PLoS One. 2017 Oct 24;12(10):e0186692. doi: 10.1371/journal.pone.0186692. eCollection 2017.

19.

Proteomics analysis of bladder cancer invasion: Targeting EIF3D for therapeutic intervention.

Latosinska A, Mokou M, Makridakis M, Mullen W, Zoidakis J, Lygirou V, Frantzi M, Katafigiotis I, Stravodimos K, Hupe MC, Dobrzynski M, Kolch W, Merseburger AS, Mischak H, Roubelakis MG, Vlahou A.

Oncotarget. 2017 Apr 20;8(41):69435-69455. doi: 10.18632/oncotarget.17279. eCollection 2017 Sep 19.

20.

Characterisation of a pucBA deletion mutant from Rhodopseudomonas palustris lacking all but the pucBAd genes.

Southall J, Henry SL, Gardiner AT, Roszak AW, Mullen W, Carey AM, Kelly SM, de Percin Northumberland CO, Cogdell RJ.

Photosynth Res. 2018 Mar;135(1-3):9-21. doi: 10.1007/s11120-017-0386-7. Epub 2017 May 31.

21.

Urine peptidomic biomarkers for diagnosis of patients with systematic lupus erythematosus.

Pejchinovski M, Siwy J, Mullen W, Mischak H, Petri MA, Burkly LC, Wei R.

Lupus. 2018 Jan;27(1):6-16. doi: 10.1177/0961203317707827. Epub 2017 May 5.

22.

Polymerization-Incompetent Uromodulin in the Pregnant Stroke-Prone Spontaneously Hypertensive Rat.

Mary S, Small HY, Siwy J, Mullen W, Giri A, Delles C.

Hypertension. 2017 May;69(5):910-918. doi: 10.1161/HYPERTENSIONAHA.116.08826. Epub 2017 Mar 27.

23.

Using the MitoB method to assess levels of reactive oxygen species in ecological studies of oxidative stress.

Salin K, Auer SK, Villasevil EM, Anderson GJ, Cairns AG, Mullen W, Hartley RC, Metcalfe NB.

Sci Rep. 2017 Jan 24;7:41228. doi: 10.1038/srep41228.

24.

Tissue Proteomics in Vascular Disease.

Albalat A, Mullen W, Husi H, Mischak H.

Methods Mol Biol. 2017;1527:53-60. doi: 10.1007/978-1-4939-6625-7_4. Review.

PMID:
28116706
25.

Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups.

Siebert S, Porter D, Paterson C, Hampson R, Gaya D, Latosinska A, Mischak H, Schanstra J, Mullen W, McInnes I.

Sci Rep. 2017 Jan 16;7:40473. doi: 10.1038/srep40473.

26.

Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis.

Siwy J, Zürbig P, Argiles A, Beige J, Haubitz M, Jankowski J, Julian BA, Linde PG, Marx D, Mischak H, Mullen W, Novak J, Ortiz A, Persson F, Pontillo C, Rossing P, Rupprecht H, Schanstra JP, Vlahou A, Vanholder R.

Nephrol Dial Transplant. 2017 Dec 1;32(12):2079-2089. doi: 10.1093/ndt/gfw337.

27.

Non-invasive FFRCT revealing severe inducible ischaemia in an anomalous right coronary artery.

Zimmermann FM, Kobayashi Y, Mullen WL, Fearon WF.

Eur Heart J. 2017 Sep 1;38(33):2569. doi: 10.1093/eurheartj/ehw542. No abstract available.

PMID:
27941015
28.

The proteome pattern cGvHD_MS14 allows early and accurate prediction of chronic GvHD after allogeneic stem cell transplantation.

Weissinger EM, Human C, Metzger J, Hambach L, Wolf D, Greinix HT, Dickinson AM, Mullen W, Jonigk D, Kuzmina Z, Kreipe H, Schweier P, Böhm O, Türüchanow I, Ihlenburg-Schwarz D, Raad J, Durban A, Schiemann M, Könecke C, Diedrich H, Holler E, Beutel G, Krauter J, Ganser A, Stadler M.

Leukemia. 2017 Mar;31(3):654-662. doi: 10.1038/leu.2016.259. Epub 2016 Sep 28.

PMID:
27677743
29.

Tomato Juice Consumption Modifies the Urinary Peptide Profile in Sprague-Dawley Rats with Induced Hepatic Steatosis.

Martín-Pozuelo G, González-Barrio R, Barberá GG, Albalat A, García-Alonso J, Mullen W, Mischak H, Periago MJ.

Int J Mol Sci. 2016 Oct 26;17(11). pii: E1789.

30.

Mitogen-Activated Protein Kinase 14 Promotes AKI.

Ortiz A, Husi H, Gonzalez-Lafuente L, Valiño-Rivas L, Fresno M, Sanz AB, Mullen W, Albalat A, Mezzano S, Vlahou T, Mischak H, Sanchez-Niño MD.

J Am Soc Nephrol. 2017 Mar;28(3):823-836. doi: 10.1681/ASN.2015080898. Epub 2016 Sep 12.

31.

Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 1. High abundance proteins, acute phase proteins and peptidomics.

Thomas FC, Mullen W, Tassi R, Ramírez-Torres A, Mudaliar M, McNeilly TN, Zadoks RN, Burchmore R, David Eckersall P.

Mol Biosyst. 2016 Aug 16;12(9):2735-47. doi: 10.1039/c6mb00239k.

32.

A urinary proteome-based classifier for the early detection of decline in glomerular filtration.

Pontillo C, Jacobs L, Staessen JA, Schanstra JP, Rossing P, Heerspink HJL, Siwy J, Mullen W, Vlahou A, Mischak H, Vanholder R, Zürbig P, Jankowski J.

Nephrol Dial Transplant. 2017 Sep 1;32(9):1510-1516. doi: 10.1093/ndt/gfw239.

PMID:
27387473
33.

Proteomic Analysis of Vitreous Humor in Retinal Vein Occlusion.

Reich M, Dacheva I, Nobl M, Siwy J, Schanstra JP, Mullen W, Koch FH, Kopitz J, Kretz FT, Auffarth GU, Koss MJ.

PLoS One. 2016 Jun 30;11(6):e0158001. doi: 10.1371/journal.pone.0158001. eCollection 2016.

34.

Acute kidney injury prediction in cardiac surgery patients by a urinary peptide pattern: a case-control validation study.

Metzger J, Mullen W, Husi H, Stalmach A, Herget-Rosenthal S, Groesdonk HV, Mischak H, Klingele M.

Crit Care. 2016 May 26;20(1):157. doi: 10.1186/s13054-016-1344-z.

35.

Urine proteome analysis in heart failure with reduced ejection fraction complicated by chronic kidney disease: feasibility, and clinical and pathogenetic correlates.

Farmakis D, Koeck T, Mullen W, Parissis J, Gogas BD, Nikolaou M, Lekakis J, Mischak H, Filippatos G.

Eur J Heart Fail. 2016 Jul;18(7):822-9. doi: 10.1002/ejhf.544. Epub 2016 May 25.

36.

Integrative analysis of extracellular and intracellular bladder cancer cell line proteome with transcriptome: improving coverage and validity of -omics findings.

Latosinska A, Makridakis M, Frantzi M, Borràs DM, Janssen B, Mullen W, Zoidakis J, Merseburger AS, Jankowski V, Mischak H, Vlahou A.

Sci Rep. 2016 May 11;6:25619. doi: 10.1038/srep25619.

37.

Development of a MALDI MS-based platform for early detection of acute kidney injury.

Carrick E, Vanmassenhove J, Glorieux G, Metzger J, Dakna M, Pejchinovski M, Jankowski V, Mansoorian B, Husi H, Mullen W, Mischak H, Vanholder R, Van Biesen W.

Proteomics Clin Appl. 2016 Jul;10(7):732-42. doi: 10.1002/prca.201500117. Epub 2016 May 17.

38.

High-Throughput LC-MS/MS Proteomic Analysis of a Mouse Model of Mesiotemporal Lobe Epilepsy Predicts Microglial Activation Underlying Disease Development.

Bitsika V, Duveau V, Simon-Areces J, Mullen W, Roucard C, Makridakis M, Mermelekas G, Savvopoulos P, Depaulis A, Vlahou A.

J Proteome Res. 2016 May 6;15(5):1546-62. doi: 10.1021/acs.jproteome.6b00003. Epub 2016 Apr 19.

PMID:
27057777
39.

Development and Validation of Urine-based Peptide Biomarker Panels for Detecting Bladder Cancer in a Multi-center Study.

Frantzi M, van Kessel KE, Zwarthoff EC, Marquez M, Rava M, Malats N, Merseburger AS, Katafigiotis I, Stravodimos K, Mullen W, Zoidakis J, Makridakis M, Pejchinovski M, Critselis E, Lichtinghagen R, Brand K, Dakna M, Roubelakis MG, Theodorescu D, Vlahou A, Mischak H, Anagnou NP.

Clin Cancer Res. 2016 Aug 15;22(16):4077-86. doi: 10.1158/1078-0432.CCR-15-2715. Epub 2016 Mar 29.

40.

Effects of a beverage rich in (poly)phenols on established and novel risk markers for vascular disease in medically uncomplicated overweight or obese subjects: A four week randomized placebo-controlled trial.

Mullan A, Delles C, Ferrell W, Mullen W, Edwards CA, McColl JH, Roberts SA, Lean ME, Sattar N.

Atherosclerosis. 2016 Mar;246:169-76. doi: 10.1016/j.atherosclerosis.2016.01.004. Epub 2016 Jan 6.

PMID:
26797134
41.

Urinary Peptide Analysis Differentiates Pancreatic Cancer From Chronic Pancreatitis.

Schönemeier B, Metzger J, Klein J, Husi H, Bremer B, Armbrecht N, Dakna M, Schanstra JP, Rosendahl J, Wiegand J, Jäger M, Mullen W, Breuil B, Plentz RR, Lichtinghagen R, Brand K, Kühnel F, Mischak H, Manns MP, Lankisch TO.

Pancreas. 2016 Aug;45(7):1018-26. doi: 10.1097/MPA.0000000000000573.

PMID:
26784907
42.

Proteomics of vitreous in neovascular age-related macular degeneration.

Nobl M, Reich M, Dacheva I, Siwy J, Mullen W, Schanstra JP, Choi CY, Kopitz J, Kretz FT, Auffarth GU, Koch F, Koss MJ.

Exp Eye Res. 2016 May;146:107-17. doi: 10.1016/j.exer.2016.01.001. Epub 2016 Jan 6.

PMID:
26769219
43.

Synthesis of an azido-tagged low affinity ratiometric calcium sensor.

Caldwell ST, Cairns AG, Olson M, Chalmers S, Sandison M, Mullen W, McCarron JG, Hartley RC.

Tetrahedron. 2015 Dec 23;71(51):9571-9578.

44.

Urinary proteomic profiling in severe obesity and obstructive sleep apnoea with CPAP treatment.

Seetho IW, Ramírez-Torres A, Albalat A, Mullen W, Mischak H, Parker RJ, Craig S, Duffy N, Hardy KJ, Burniston JG, Wilding JP.

Sleep Sci. 2015 Apr-Jun;8(2):58-67. doi: 10.1016/j.slsci.2015.06.004. Epub 2015 Jul 17.

45.

Identification of ageing-associated naturally occurring peptides in human urine.

Nkuipou-Kenfack E, Bhat A, Klein J, Jankowski V, Mullen W, Vlahou A, Dakna M, Koeck T, Schanstra JP, Zürbig P, Rudolph KL, Schumacher B, Pich A, Mischak H.

Oncotarget. 2015 Oct 27;6(33):34106-17. doi: 10.18632/oncotarget.5896.

46.

Individuals with higher metabolic rates have lower levels of reactive oxygen species in vivo.

Salin K, Auer SK, Rudolf AM, Anderson GJ, Cairns AG, Mullen W, Hartley RC, Selman C, Metcalfe NB.

Biol Lett. 2015 Sep;11(9):20150538. doi: 10.1098/rsbl.2015.0538.

47.

Comparative Analysis of Label-Free and 8-Plex iTRAQ Approach for Quantitative Tissue Proteomic Analysis.

Latosinska A, Vougas K, Makridakis M, Klein J, Mullen W, Abbas M, Stravodimos K, Katafigiotis I, Merseburger AS, Zoidakis J, Mischak H, Vlahou A, Jankowski V.

PLoS One. 2015 Sep 2;10(9):e0137048. doi: 10.1371/journal.pone.0137048. eCollection 2015. Erratum in: PLoS One. 2015;10(10):e0139268.

48.

Comparison of Depletion Strategies for the Enrichment of Low-Abundance Proteins in Urine.

Filip S, Vougas K, Zoidakis J, Latosinska A, Mullen W, Spasovski G, Mischak H, Vlahou A, Jankowski J.

PLoS One. 2015 Jul 24;10(7):e0133773. doi: 10.1371/journal.pone.0133773. eCollection 2015.

49.

New perspectives on bioactivity of olive oil: evidence from animal models, human interventions and the use of urinary proteomic biomarkers.

Silva S, Combet E, Figueira ME, Koeck T, Mullen W, Bronze MR.

Proc Nutr Soc. 2015 Aug;74(3):268-81. doi: 10.1017/S0029665115002323. Review.

PMID:
26186673
50.

New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis.

Glorieux G, Mullen W, Duranton F, Filip S, Gayrard N, Husi H, Schepers E, Neirynck N, Schanstra JP, Jankowski J, Mischak H, Argilés À, Vanholder R, Vlahou A, Klein J.

Nephrol Dial Transplant. 2015 Nov;30(11):1842-52. doi: 10.1093/ndt/gfv254. Epub 2015 Jul 9.

PMID:
26160894

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