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Items: 1 to 50 of 261

1.

Chronic white matter degeneration, but no tau pathology at 1-year post-repetitive mild traumatic brain injury in tau transgenic model.

Mouzon BC, Bachmeier C, Ojo J, Acker C, Ferguson S, Crynen G, Davies P, Mullan M, Stewart W, Crawford FC.

J Neurotrauma. 2018 Jul 11. doi: 10.1089/neu.2018.5720. [Epub ahead of print]

PMID:
29993324
2.

Impact of age on acute post-TBI neuropathology in mice expressing humanized tau: a Chronic Effects of Neurotrauma Consortium Study.

Mouzon B, Saltiel N, Ferguson S, Ojo J, Lungmus C, Lynch C, Algamal M, Morin A, Carper B, Bieler G, Mufson EJ, Stewart W, Mullan M, Crawford F.

Brain Inj. 2018 Jun 21:1-10. doi: 10.1080/02699052.2018.1486457. [Epub ahead of print]

PMID:
29927671
3.

Lifelong behavioral and neuropathological consequences of repetitive mild traumatic brain injury.

Mouzon BC, Bachmeier C, Ojo JO, Acker CM, Ferguson S, Paris D, Ait-Ghezala G, Crynen G, Davies P, Mullan M, Stewart W, Crawford F.

Ann Clin Transl Neurol. 2017 Dec 14;5(1):64-80. doi: 10.1002/acn3.510. eCollection 2018 Jan.

4.

Negative Impact of Female Sex on Outcomes from Repetitive Mild Traumatic Brain Injury in hTau Mice Is Age Dependent: A Chronic Effects of Neurotrauma Consortium Study.

Ferguson SA, Mouzon BC, Lynch C, Lungmus C, Morin A, Crynen G, Carper B, Bieler G, Mufson EJ, Stewart W, Mullan M, Crawford F.

Front Aging Neurosci. 2017 Dec 22;9:416. doi: 10.3389/fnagi.2017.00416. eCollection 2017.

5.

Synoptic operative reporting: assessing the completeness, accuracy, reliability, and efficiency of synoptic reporting for Roux-en-Y gastric bypass.

Stogryn SE, Hardy K, Mullan MJ, Park J, Andrew C, Vergis A.

Surg Endosc. 2018 Apr;32(4):1729-1739. doi: 10.1007/s00464-017-5855-8. Epub 2017 Sep 15.

PMID:
28917006
6.

Alzheimer's disease pathological lesions activate the spleen tyrosine kinase.

Schweig JE, Yao H, Beaulieu-Abdelahad D, Ait-Ghezala G, Mouzon B, Crawford F, Mullan M, Paris D.

Acta Neuropathol Commun. 2017 Sep 6;5(1):69. doi: 10.1186/s40478-017-0472-2.

7.

Plasma cytokine IL-6 levels and subjective cognitive decline: preliminary findings.

Keegan AP, Paris D, Luis CA, Abdullah L, Ait-Ghezala G, Beaulieu-Abdelahad D, Pryor M, Chaykin J, Crynen G, Crawford F, Mullan M.

Int J Geriatr Psychiatry. 2018 Feb;33(2):358-363. doi: 10.1002/gps.4752. Epub 2017 Jun 22.

PMID:
28639714
8.

Pathways linking car transport for young adults and the public health in Northern Ireland: a qualitative study to inform the evaluation of graduated driver licensing.

Christie N, Steinbach R, Green J, Mullan MP, Prior L.

BMC Public Health. 2017 Jun 7;17(1):551. doi: 10.1186/s12889-017-4470-x.

9.

High-Throughput Screening To Identify Potent and Specific Inhibitors of Microbial Sulfate Reduction.

Carlson HK, Mullan MR, Mosqueda LA, Chen S, Arkin MR, Coates JD.

Environ Sci Technol. 2017 Jun 20;51(12):7278-7285. doi: 10.1021/acs.est.7b00686. Epub 2017 May 26.

PMID:
28492331
10.

Phospholipid profiling of plasma from GW veterans and rodent models to identify potential biomarkers of Gulf War Illness.

Emmerich T, Zakirova Z, Klimas N, Sullivan K, Shetty AK, Evans JE, Ait-Ghezala G, Laco GS, Hattiangady B, Shetty GA, Mullan M, Crynen G, Abdullah L, Crawford F.

PLoS One. 2017 Apr 28;12(4):e0176634. doi: 10.1371/journal.pone.0176634. eCollection 2017.

11.

Electronic synoptic reporting: assessing the completeness of synoptic and narrative reports for Roux-en-Y gastric bypass.

Vergis A, Stogryn SE, Mullan MJ, Hardy K.

Surg Obes Relat Dis. 2017 Nov;13(11):1863-1868. doi: 10.1016/j.soard.2017.02.027. Epub 2017 Mar 7.

PMID:
28433464
12.

Complementary proteomic approaches reveal mitochondrial dysfunction, immune and inflammatory dysregulation in a mouse model of Gulf War Illness.

Zakirova Z, Reed J, Crynen G, Horne L, Hassan S, Mathura V, Mullan M, Crawford F, Ait-Ghezala G.

Proteomics Clin Appl. 2017 Sep;11(9-10). doi: 10.1002/prca.201600190. Epub 2017 May 12.

13.

Increased Plasma Beta-Secretase 1 May Predict Conversion to Alzheimer's Disease Dementia in Individuals With Mild Cognitive Impairment.

Shen Y, Wang H, Sun Q, Yao H, Keegan AP, Mullan M, Wilson J, Lista S, Leyhe T, Laske C, Rujescu D, Levey A, Wallin A, Blennow K, Li R, Hampel H.

Biol Psychiatry. 2018 Mar 1;83(5):447-455. doi: 10.1016/j.biopsych.2017.02.007. Epub 2017 Mar 27.

PMID:
28359566
14.

APOE ε4 specific imbalance of arachidonic acid and docosahexaenoic acid in serum phospholipids identifies individuals with preclinical Mild Cognitive Impairment/Alzheimer's Disease.

Abdullah L, Evans JE, Emmerich T, Crynen G, Shackleton B, Keegan AP, Luis C, Tai L, LaDu MJ, Mullan M, Crawford F, Bachmeier C.

Aging (Albany NY). 2017 Mar 23;9(3):964-985. doi: 10.18632/aging.101203.

15.

Translational potential of long-term decreases in mitochondrial lipids in a mouse model of Gulf War Illness.

Abdullah L, Evans JE, Joshi U, Crynen G, Reed J, Mouzon B, Baumann S, Montague H, Zakirova Z, Emmerich T, Bachmeier C, Klimas N, Sullivan K, Mullan M, Ait-Ghezala G, Crawford F.

Toxicology. 2016 Nov 30;372:22-33. doi: 10.1016/j.tox.2016.10.012. Epub 2016 Oct 29.

PMID:
27931520
16.

Acute or Delayed Treatment with Anatabine Improves Spatial Memory and Reduces Pathological Sequelae at Late Time-Points after Repetitive Mild Traumatic Brain Injury.

Ferguson S, Mouzon B, Paris D, Aponte D, Abdullah L, Stewart W, Mullan M, Crawford F.

J Neurotrauma. 2017 Apr 15;34(8):1676-1691. doi: 10.1089/neu.2016.4636. Epub 2017 Jan 20.

17.

Mild TBI Results in a Long-Term Decrease in Circulating Phospholipids in a Mouse Model of Injury.

Emmerich T, Abdullah L, Ojo J, Mouzon B, Nguyen T, Laco GS, Crynen G, Evans JE, Reed J, Mullan M, Crawford F.

Neuromolecular Med. 2017 Mar;19(1):122-135. doi: 10.1007/s12017-016-8436-4. Epub 2016 Aug 19.

PMID:
27540748
18.

European multicentre double-blind placebo-controlled trial of Nilvadipine in mild-to-moderate Alzheimer's disease-the substudy protocols: NILVAD frailty; NILVAD blood and genetic biomarkers; NILVAD cerebrospinal fluid biomarkers; NILVAD cerebral blood flow.

Meulenbroek O, O'Dwyer S, de Jong D, van Spijker G, Kennelly S, Cregg F, Olde Rikkert M, Abdullah L, Wallin A, Walsh C, Coen R, Kenny RA, Daly L, Segurado R, Borjesson-Hanson A, Crawford F, Mullan M, Lucca U, Banzi R, Pasquier F, Breuilh L, Riepe M, Kalman J, Molloy W, Tsolaki M, Howard R, Adams J, Gaynor S, Lawlor B.

BMJ Open. 2016 Jul 19;6(7):e011584. doi: 10.1136/bmjopen-2016-011584.

19.

Chronic Repetitive Mild Traumatic Brain Injury Results in Reduced Cerebral Blood Flow, Axonal Injury, Gliosis, and Increased T-Tau and Tau Oligomers.

Ojo JO, Mouzon B, Algamal M, Leary P, Lynch C, Abdullah L, Evans J, Mullan M, Bachmeier C, Stewart W, Crawford F.

J Neuropathol Exp Neurol. 2016 Jul;75(7):636-55. doi: 10.1093/jnen/nlw035. Epub 2016 May 31.

20.

Sub-Chronic Neuropathological and Biochemical Changes in Mouse Visual System after Repetitive Mild Traumatic Brain Injury.

Tzekov R, Dawson C, Orlando M, Mouzon B, Reed J, Evans J, Crynen G, Mullan M, Crawford F.

PLoS One. 2016 Apr 18;11(4):e0153608. doi: 10.1371/journal.pone.0153608. eCollection 2016.

21.

Comparison of the psychometric properties of four dementia knowledge measures: Which test should be used with dementia care staff?

Sullivan KA, Mullan MA.

Australas J Ageing. 2017 Mar;36(1):38-45. doi: 10.1111/ajag.12299. Epub 2016 Mar 11.

PMID:
26970426
22.

Plasma Lipidomic Profiling in a Military Population of Mild Traumatic Brain Injury and Post-Traumatic Stress Disorder with Apolipoprotein E ɛ4-Dependent Effect.

Emmerich T, Abdullah L, Crynen G, Dretsch M, Evans J, Ait-Ghezala G, Reed J, Montague H, Chaytow H, Mathura V, Martin J, Pelot R, Ferguson S, Bishop A, Phillips J, Mullan M, Crawford F.

J Neurotrauma. 2016 Jul 15;33(14):1331-48. doi: 10.1089/neu.2015.4061. Epub 2016 Mar 9.

PMID:
26714394
23.

Ultrastructural Changes in the White and Gray Matter of Mice at Chronic Time Points After Repeated Concussive Head Injury.

Ojo JO, Bachmeier C, Mouzon BC, Tzekov R, Mullan M, Davies H, Stewart MG, Crawford F.

J Neuropathol Exp Neurol. 2015 Oct;74(10):1012-35. doi: 10.1097/NEN.0000000000000247.

PMID:
26360375
24.

Correction: Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD.

Verma M, Beaulieu-Abdelahad D, Ait-Ghezala G, Li R, Crawford F, Mullan M, Paris D.

PLoS One. 2015 Jul 31;10(7):e0134776. doi: 10.1371/journal.pone.0134776. eCollection 2015.

25.

Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD.

Verma M, Beaulieu-Abdelahad D, Ait-Ghezala G, Li R, Crawford F, Mullan M, Paris D.

PLoS One. 2015 May 26;10(5):e0128224. doi: 10.1371/journal.pone.0128224. eCollection 2015. Erratum in: PLoS One. 2015;10(7):e0134776.

26.

Gulf War agent exposure causes impairment of long-term memory formation and neuropathological changes in a mouse model of Gulf War Illness.

Zakirova Z, Tweed M, Crynen G, Reed J, Abdullah L, Nissanka N, Mullan M, Mullan MJ, Mathura V, Crawford F, Ait-Ghezala G.

PLoS One. 2015 Mar 18;10(3):e0119579. doi: 10.1371/journal.pone.0119579. eCollection 2015.

27.

Positive attitudes and person-centred care predict of sense of competence in dementia care staff.

Mullan MA, Sullivan KA.

Aging Ment Health. 2016;20(4):407-14. doi: 10.1080/13607863.2015.1018865. Epub 2015 Mar 11.

PMID:
25760319
28.

Monofluorophosphate is a selective inhibitor of respiratory sulfate-reducing microorganisms.

Carlson HK, Stoeva MK, Justice NB, Sczesnak A, Mullan MR, Mosqueda LA, Kuehl JV, Deutschbauer AM, Arkin AP, Coates JD.

Environ Sci Technol. 2015 Mar 17;49(6):3727-36. doi: 10.1021/es505843z. Epub 2015 Mar 4.

PMID:
25698072
29.

Mechanisms of direct inhibition of the respiratory sulfate-reduction pathway by (per)chlorate and nitrate.

Carlson HK, Kuehl JV, Hazra AB, Justice NB, Stoeva MK, Sczesnak A, Mullan MR, Iavarone AT, Engelbrektson A, Price MN, Deutschbauer AM, Arkin AP, Coates JD.

ISME J. 2015 Jun;9(6):1295-305. doi: 10.1038/ismej.2014.216. Epub 2014 Nov 18.

30.

The spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation.

Paris D, Ait-Ghezala G, Bachmeier C, Laco G, Beaulieu-Abdelahad D, Lin Y, Jin C, Crawford F, Mullan M.

J Biol Chem. 2014 Dec 5;289(49):33927-44. doi: 10.1074/jbc.M114.608091. Epub 2014 Oct 20.

31.

NILVAD protocol: a European multicentre double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease.

Lawlor B, Kennelly S, O'Dwyer S, Cregg F, Walsh C, Coen R, Kenny RA, Howard R, Murphy C, Adams J, Daly L, Segurado R, Gaynor S, Crawford F, Mullan M, Lucca U, Banzi R, Pasquier F, Breuilh L, Riepe M, Kalman J, Wallin A, Borjesson A, Molloy W, Tsolaki M, Olde Rikkert M.

BMJ Open. 2014 Oct 9;4(10):e006364. doi: 10.1136/bmjopen-2014-006364. Erratum in: BMJ Open. 2015;5(9):e006364.

32.

Lipidomic analyses identify injury-specific phospholipid changes 3 mo after traumatic brain injury.

Abdullah L, Evans JE, Ferguson S, Mouzon B, Montague H, Reed J, Crynen G, Emmerich T, Crocker M, Pelot R, Mullan M, Crawford F.

FASEB J. 2014 Dec;28(12):5311-21. doi: 10.1096/fj.14-258228. Epub 2014 Sep 10.

PMID:
25208845
33.

Apolipoprotein E isoform-specific effects on lipoprotein receptor processing.

Bachmeier C, Shackleton B, Ojo J, Paris D, Mullan M, Crawford F.

Neuromolecular Med. 2014 Dec;16(4):686-96.

34.

Neurobehavioral, neuropathological and biochemical profiles in a novel mouse model of co-morbid post-traumatic stress disorder and mild traumatic brain injury.

Ojo JO, Greenberg MB, Leary P, Mouzon B, Bachmeier C, Mullan M, Diamond DM, Crawford F.

Front Behav Neurosci. 2014 Jun 23;8:213. doi: 10.3389/fnbeh.2014.00213. eCollection 2014.

35.

General paediatric surgery: a survey of Northern Ireland general surgery specialist registrars.

Mullan MJ, Grannell M, Dick AC.

Ulster Med J. 2014 Jan;83(1):50-1. No abstract available.

36.

Repetitive mild traumatic brain injury causes optic nerve and retinal damage in a mouse model.

Tzekov R, Quezada A, Gautier M, Biggins D, Frances C, Mouzon B, Jamison J, Mullan M, Crawford F.

J Neuropathol Exp Neurol. 2014 Apr;73(4):345-61. doi: 10.1097/NEN.0000000000000059.

PMID:
24607965
37.

Vision function abnormalities in Alzheimer disease.

Tzekov R, Mullan M.

Surv Ophthalmol. 2014 Jul-Aug;59(4):414-33. doi: 10.1016/j.survophthal.2013.10.002. Epub 2013 Oct 22. Review.

PMID:
24309127
38.

Chronic neuropathological and neurobehavioral changes in a repetitive mild traumatic brain injury model.

Mouzon BC, Bachmeier C, Ferro A, Ojo JO, Crynen G, Acker CM, Davies P, Mullan M, Stewart W, Crawford F.

Ann Neurol. 2014 Feb;75(2):241-54. doi: 10.1002/ana.24064. Epub 2014 Feb 20.

PMID:
24243523
39.

Chronic elevation of phosphocholine containing lipids in mice exposed to Gulf War agents pyridostigmine bromide and permethrin.

Abdullah L, Evans JE, Montague H, Reed JM, Moser A, Crynen G, Gonzalez A, Zakirova Z, Ross I, Mullan C, Mullan M, Ait-Ghezala G, Crawford F.

Neurotoxicol Teratol. 2013 Nov-Dec;40:74-84. doi: 10.1016/j.ntt.2013.10.002. Epub 2013 Oct 17.

PMID:
24140745
40.
41.

Effect of venlafaxine and desvenlafaxine on drug efflux protein expression and biodistribution in vivo.

Bachmeier C, Levin GM, Beaulieu-Abdelahad D, Reed J, Mullan M.

J Pharm Sci. 2013 Oct;102(10):3838-43. doi: 10.1002/jps.23680. Epub 2013 Jul 29.

PMID:
23897419
42.

Role of the cannabinoid system in the transit of beta-amyloid across the blood-brain barrier.

Bachmeier C, Beaulieu-Abdelahad D, Mullan M, Paris D.

Mol Cell Neurosci. 2013 Sep;56:255-62. doi: 10.1016/j.mcn.2013.06.004. Epub 2013 Jul 3.

PMID:
23831388
43.

Splenic injury after colonoscopy requiring splenectomy.

McBride R, Dasari B, Magowan H, Mullan M, Yousaf M, Mackle E.

BMJ Case Rep. 2013 Jun 3;2013. pii: bcr2013009126. doi: 10.1136/bcr-2013-009126.

44.

Amelioration of experimental autoimmune encephalomyelitis by anatabine.

Paris D, Beaulieu-Abdelahad D, Mullan M, Ait-Ghezala G, Mathura V, Bachmeier C, Crawford F, Mullan MJ.

PLoS One. 2013;8(1):e55392. doi: 10.1371/journal.pone.0055392. Epub 2013 Jan 30.

45.

Repetitive mild traumatic brain injury augments tau pathology and glial activation in aged hTau mice.

Ojo JO, Mouzon B, Greenberg MB, Bachmeier C, Mullan M, Crawford F.

J Neuropathol Exp Neurol. 2013 Feb;72(2):137-51. doi: 10.1097/NEN.0b013e3182814cdf.

PMID:
23334597
46.

Anti-inflammatory activity of anatabine via inhibition of STAT3 phosphorylation.

Paris D, Beaulieu-Abdelahad D, Abdullah L, Bachmeier C, Ait-Ghezala G, Reed J, Verma M, Crawford F, Mullan M.

Eur J Pharmacol. 2013 Jan 5;698(1-3):145-53. doi: 10.1016/j.ejphar.2012.11.017. Epub 2012 Nov 21.

PMID:
23178521
47.

Plasma microRNA biomarkers for detection of mild cognitive impairment.

Sheinerman KS, Tsivinsky VG, Crawford F, Mullan MJ, Abdullah L, Umansky SR.

Aging (Albany NY). 2012 Sep;4(9):590-605.

48.

Repetitive mild traumatic brain injury in a mouse model produces learning and memory deficits accompanied by histological changes.

Mouzon B, Chaytow H, Crynen G, Bachmeier C, Stewart J, Mullan M, Stewart W, Crawford F.

J Neurotrauma. 2012 Dec 10;29(18):2761-73. doi: 10.1089/neu.2012.2498. Epub 2012 Nov 23.

PMID:
22900595
49.

Stimulation of the retinoid X receptor facilitates beta-amyloid clearance across the blood-brain barrier.

Bachmeier C, Beaulieu-Abdelahad D, Crawford F, Mullan M, Paris D.

J Mol Neurosci. 2013 Feb;49(2):270-6. doi: 10.1007/s12031-012-9866-6. Epub 2012 Aug 14.

PMID:
22890420
50.

Lipidomic profiling of phosphocholine-containing brain lipids in mice with sensorimotor deficits and anxiety-like features after exposure to Gulf War agents.

Abdullah L, Evans JE, Bishop A, Reed JM, Crynen G, Phillips J, Pelot R, Mullan MA, Ferro A, Mullan CM, Mullan MJ, Ait-Ghezala G, Crawford FC.

Neuromolecular Med. 2012 Dec;14(4):349-61. doi: 10.1007/s12017-012-8192-z. Epub 2012 Jul 14.

PMID:
22798222

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