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Items: 1 to 50 of 98

1.

Bevacizumab and temozolomide in patients with first recurrence of WHO grade II and III glioma, without 1p/19q co-deletion (TAVAREC): a randomised controlled phase 2 EORTC trial.

van den Bent MJ, Klein M, Smits M, Reijneveld JC, French PJ, Clement P, de Vos FYF, Wick A, Mulholland PJ, Taphoorn MJB, Lewis J, Weller M, Chinot OL, Kros JM, de Heer I, Verschuere T, Coens C, Golfinopoulos V, Gorlia T, Idbaih A.

Lancet Oncol. 2018 Sep;19(9):1170-1179. doi: 10.1016/S1470-2045(18)30362-0. Epub 2018 Aug 13.

PMID:
30115593
2.

Increasing Brain-Derived Neurotrophic Factor (BDNF) in medial prefrontal cortex selectively reduces excessive drinking in ethanol dependent mice.

Haun HL, Griffin WC, Lopez MF, Solomon MG, Mulholland PJ, Woodward JJ, McGinty JF, Ron D, Becker HC.

Neuropharmacology. 2018 Sep 15;140:35-42. doi: 10.1016/j.neuropharm.2018.07.031. Epub 2018 Jul 26.

PMID:
30056122
3.

Use of a Binocular Optical Coherence Tomography System to Evaluate Strabismus in Primary Position.

Chopra R, Mulholland PJ, Tailor VK, Anderson RS, Keane PA.

JAMA Ophthalmol. 2018 Jul 1;136(7):811-817. doi: 10.1001/jamaophthalmol.2018.1973.

PMID:
29852032
4.

Identification and validation of midbrain Kcnq4 regulation of heavy alcohol consumption in rodents.

McGuier NS, Rinker JA, Cannady R, Fulmer DB, Jones SR, Hoffman M, Mulholland PJ.

Neuropharmacology. 2018 Aug;138:10-19. doi: 10.1016/j.neuropharm.2018.05.020. Epub 2018 May 25.

PMID:
29775679
5.

Optimising the glaucoma signal/noise ratio by mapping changes in spatial summation with area-modulated perimetric stimuli.

Rountree L, Mulholland PJ, Anderson RS, Garway-Heath DF, Morgan JE, Redmond T.

Sci Rep. 2018 Feb 1;8(1):2172. doi: 10.1038/s41598-018-20480-4.

6.

Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior.

Cannady R, Rinker JA, Nimitvilai S, Woodward JJ, Mulholland PJ.

Handb Exp Pharmacol. 2018;248:311. doi: 10.1007/164_2017_90.

PMID:
29374839
7.

Donepezil Reverses Dendritic Spine Morphology Adaptations and Fmr1 Epigenetic Modifications in Hippocampus of Adult Rats After Adolescent Alcohol Exposure.

Mulholland PJ, Teppen TL, Miller KM, Sexton HG, Pandey SC, Swartzwelder HS.

Alcohol Clin Exp Res. 2018 Apr;42(4):706-717. doi: 10.1111/acer.13599. Epub 2018 Feb 15.

PMID:
29336496
8.

Human Factor and Usability Testing of a Binocular Optical Coherence Tomography System.

Chopra R, Mulholland PJ, Dubis AM, Anderson RS, Keane PA.

Transl Vis Sci Technol. 2017 Aug 15;6(4):16. doi: 10.1167/tvst.6.4.16. eCollection 2017 Jul.

9.

Persistent cognitive and morphological alterations induced by repeated exposure of adolescent rats to the abused inhalant toluene.

Braunscheidel KM, Gass JT, Mulholland PJ, Floresco SB, Woodward JJ.

Neurobiol Learn Mem. 2017 Oct;144:136-146. doi: 10.1016/j.nlm.2017.07.007. Epub 2017 Jul 15.

10.

Promising pharmacogenetic targets for treating alcohol use disorder: evidence from preclinical models.

Rinker JA, Mulholland PJ.

Pharmacogenomics. 2017 Apr;18(6):555-570. doi: 10.2217/pgs-2016-0193. Epub 2017 Mar 27. Review.

11.

Prefrontal Cortex KCa2 Channels Regulate mGlu5-Dependent Plasticity and Extinction of Alcohol-Seeking Behavior.

Cannady R, McGonigal JT, Newsom RJ, Woodward JJ, Mulholland PJ, Gass JT.

J Neurosci. 2017 Apr 19;37(16):4359-4369. doi: 10.1523/JNEUROSCI.2873-16.2017. Epub 2017 Mar 20.

12.

Effects of Repeated Ethanol Exposures on NMDA Receptor Expression and Locomotor Sensitization in Mice Expressing Ethanol Resistant NMDA Receptors.

den Hartog CR, Gilstrap M, Eaton B, Lench DH, Mulholland PJ, Homanics GE, Woodward JJ.

Front Neurosci. 2017 Feb 21;11:84. doi: 10.3389/fnins.2017.00084. eCollection 2017.

13.

Orbitofrontal Neuroadaptations and Cross-Species Synaptic Biomarkers in Heavy-Drinking Macaques.

Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ.

J Neurosci. 2017 Mar 29;37(13):3646-3660. doi: 10.1523/JNEUROSCI.0133-17.2017. Epub 2017 Mar 7.

14.

Ethanol Dependence Abolishes Monoamine and GIRK (Kir3) Channel Inhibition of Orbitofrontal Cortex Excitability.

Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ.

Neuropsychopharmacology. 2017 Aug;42(9):1800-1812. doi: 10.1038/npp.2017.22. Epub 2017 Jan 31.

15.

Relationship between Psychophysical Measures of Retinal Ganglion Cell Density and In Vivo Measures of Cone Density in Glaucoma.

Matlach J, Mulholland PJ, Cilkova M, Chopra R, Shah N, Redmond T, Dakin SC, Garway-Heath DF, Anderson RS.

Ophthalmology. 2017 Mar;124(3):310-319. doi: 10.1016/j.ophtha.2016.10.029. Epub 2016 Dec 5.

PMID:
27932223
16.

Kv7 channels in the nucleus accumbens are altered by chronic drinking and are targets for reducing alcohol consumption.

McGuier NS, Griffin WC 3rd, Gass JT, Padula AE, Chesler EJ, Mulholland PJ.

Addict Biol. 2016 Nov;21(6):1097-1112. doi: 10.1111/adb.12279. Epub 2015 Jun 23.

17.

Binge-Like Alcohol Exposure During Adolescence Disrupts Dopaminergic Neurotransmission in the Adult Prelimbic Cortex.

Trantham-Davidson H, Centanni SW, Garr SC, New NN, Mulholland PJ, Gass JT, Glover EJ, Floresco SB, Crews FT, Krishnan HR, Pandey SC, Chandler LJ.

Neuropsychopharmacology. 2017 Apr;42(5):1024-1036. doi: 10.1038/npp.2016.190. Epub 2016 Sep 13.

18.

Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking.

Rinker JA, Fulmer DB, Trantham-Davidson H, Smith ML, Williams RW, Lopez MF, Randall PK, Chandler LJ, Miles MF, Becker HC, Mulholland PJ.

Alcohol. 2017 Feb;58:33-45. doi: 10.1016/j.alcohol.2016.05.007. Epub 2016 Jun 27.

19.

A Cancer Research UK First Time in Human Phase I Trial of IMA950 (Novel Multipeptide Therapeutic Vaccine) in Patients with Newly Diagnosed Glioblastoma.

Rampling R, Peoples S, Mulholland PJ, James A, Al-Salihi O, Twelves CJ, McBain C, Jefferies S, Jackson A, Stewart W, Lindner J, Kutscher S, Hilf N, McGuigan L, Peters J, Hill K, Schoor O, Singh-Jasuja H, Halford SE, Ritchie JW.

Clin Cancer Res. 2016 Oct 1;22(19):4776-4785. Epub 2016 May 25.

20.

Signals from the Fourth Dimension Regulate Drug Relapse.

Mulholland PJ, Chandler LJ, Kalivas PW.

Trends Neurosci. 2016 Jul;39(7):472-485. doi: 10.1016/j.tins.2016.04.007. Epub 2016 May 10. Review.

21.

FMRP Mediates Chronic Ethanol-Induced Changes in NMDA, Kv4.2, and KChIP3 Expression in the Hippocampus.

Spencer KB, Mulholland PJ, Chandler LJ.

Alcohol Clin Exp Res. 2016 Jun;40(6):1251-61. doi: 10.1111/acer.13060. Epub 2016 May 5. Erratum in: Alcohol Clin Exp Res. 2016 Sep;40(9):2021.

22.

Spatiotemporal Summation of Perimetric Stimuli in Early Glaucoma.

Mulholland PJ, Redmond T, Garway-Heath DF, Zlatkova MB, Anderson RS.

Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6473-82. doi: 10.1167/iovs.15-16921.

PMID:
26447981
23.

The Effect of Age on the Temporal Summation of Achromatic Perimetric Stimuli.

Mulholland PJ, Redmond T, Garway-Heath DF, Zlatkova MB, Anderson RS.

Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6467-72. doi: 10.1167/iovs.15-16920.

PMID:
26447980
24.

Effect of varying CRT refresh rate on the measurement of temporal summation.

Mulholland PJ, Zlatkova MB, Redmond T, Garway-Heath DF, Anderson RS.

Ophthalmic Physiol Opt. 2015 Sep;35(5):582-90. doi: 10.1111/opo.12227.

PMID:
26303451
25.

Chronic Intermittent Ethanol Exposure Enhances the Excitability and Synaptic Plasticity of Lateral Orbitofrontal Cortex Neurons and Induces a Tolerance to the Acute Inhibitory Actions of Ethanol.

Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ.

Neuropsychopharmacology. 2016 Mar;41(4):1112-27. doi: 10.1038/npp.2015.250. Epub 2015 Aug 9.

26.

Chronic intermittent ethanol induced axon and myelin degeneration is attenuated by calpain inhibition.

Samantaray S, Knaryan VH, Patel KS, Mulholland PJ, Becker HC, Banik NL.

Brain Res. 2015 Oct 5;1622:7-21. doi: 10.1016/j.brainres.2015.06.014. Epub 2015 Jun 20.

27.

Chronic intermittent ethanol exposure and withdrawal leads to adaptations in nucleus accumbens core postsynaptic density proteome and dendritic spines.

Uys JD, McGuier NS, Gass JT, Griffin WC 3rd, Ball LE, Mulholland PJ.

Addict Biol. 2016 May;21(3):560-74. doi: 10.1111/adb.12238. Epub 2015 Mar 17.

28.

Homer2 deletion alters dendritic spine morphology but not alcohol-associated adaptations in GluN2B-containing N-methyl-D-aspartate receptors in the nucleus accumbens.

McGuier NS, Padula AE, Mulholland PJ, Chandler LJ.

Front Pharmacol. 2015 Feb 23;6:28. doi: 10.3389/fphar.2015.00028. eCollection 2015.

29.

KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction.

Padula AE, Griffin WC 3rd, Lopez MF, Nimitvilai S, Cannady R, McGuier NS, Chesler EJ, Miles MF, Williams RW, Randall PK, Woodward JJ, Becker HC, Mulholland PJ.

Neuropsychopharmacology. 2015 Jul;40(8):1928-39. doi: 10.1038/npp.2015.42. Epub 2015 Feb 9.

30.

Estimating the critical duration for temporal summation of standard achromatic perimetric stimuli.

Mulholland PJ, Redmond T, Garway-Heath DF, Zlatkova MB, Anderson RS.

Invest Ophthalmol Vis Sci. 2014 Dec 16;56(1):431-7. doi: 10.1167/iovs.14-15304.

PMID:
25515580
31.

Neuroplasticity of A-type potassium channel complexes induced by chronic alcohol exposure enhances dendritic calcium transients in hippocampus.

Mulholland PJ, Spencer KB, Hu W, Kroener S, Chandler LJ.

Psychopharmacology (Berl). 2015 Jun;232(11):1995-2006. doi: 10.1007/s00213-014-3835-4. Epub 2014 Dec 17.

32.

Withdrawal from chronic intermittent alcohol exposure increases dendritic spine density in the lateral orbitofrontal cortex of mice.

McGuier NS, Padula AE, Lopez MF, Woodward JJ, Mulholland PJ.

Alcohol. 2015 Feb;49(1):21-7. doi: 10.1016/j.alcohol.2014.07.017. Epub 2014 Nov 3.

33.

Adolescent alcohol exposure alters GABAA receptor subunit expression in adult hippocampus.

Centanni SW, Teppen T, Risher ML, Fleming RL, Moss JL, Acheson SK, Mulholland PJ, Pandey SC, Chandler LJ, Swartzwelder HS.

Alcohol Clin Exp Res. 2014 Nov;38(11):2800-8. doi: 10.1111/acer.12562.

34.

Neurochemical mechanisms of alcohol withdrawal.

Becker HC, Mulholland PJ.

Handb Clin Neurol. 2014;125:133-56. doi: 10.1016/B978-0-444-62619-6.00009-4. Review.

PMID:
25307573
35.

Glutathione and redox signaling in substance abuse.

Uys JD, Mulholland PJ, Townsend DM.

Biomed Pharmacother. 2014 Jul;68(6):799-807. doi: 10.1016/j.biopha.2014.06.001. Epub 2014 Jun 24. Review.

36.

Chronic alcohol disrupts dopamine receptor activity and the cognitive function of the medial prefrontal cortex.

Trantham-Davidson H, Burnett EJ, Gass JT, Lopez MF, Mulholland PJ, Centanni SW, Floresco SB, Chandler LJ.

J Neurosci. 2014 Mar 5;34(10):3706-18. doi: 10.1523/JNEUROSCI.0623-13.2014. Erratum in: J Neurosci. 2014 Apr 30;34(18):6422.

37.

Novel anticonvulsants for reducing alcohol consumption: A review of evidence from preclinical rodent drinking models.

Padula AE, McGuier NS, Griffin WC, Lopez MF, Becker HC, Mulholland PJ.

OA Alcohol. 2013 Feb 1;1(1):2.

38.

Technical and implementation issues in using next-generation sequencing of cancers in clinical practice.

Ulahannan D, Kovac MB, Mulholland PJ, Cazier JB, Tomlinson I.

Br J Cancer. 2013 Aug 20;109(4):827-35. doi: 10.1038/bjc.2013.416. Epub 2013 Jul 25. Review.

39.

Optogenetic stimulation of MCH neurons increases sleep.

Konadhode RR, Pelluru D, Blanco-Centurion C, Zayachkivsky A, Liu M, Uhde T, Glen WB Jr, van den Pol AN, Mulholland PJ, Shiromani PJ.

J Neurosci. 2013 Jun 19;33(25):10257-63. doi: 10.1523/JNEUROSCI.1225-13.2013.

40.

Three different brain tumours evolving from a common origin.

Forshew T, Lewis P, Waldman A, Peterson D, Glaser M, Brock C, Sheer D, Mulholland PJ.

Oncogenesis. 2013 Apr 1;2:e41. doi: 10.1038/oncsis.2013.1.

41.

Ethanol reduces neuronal excitability of lateral orbitofrontal cortex neurons via a glycine receptor dependent mechanism.

Badanich KA, Mulholland PJ, Beckley JT, Trantham-Davidson H, Woodward JJ.

Neuropsychopharmacology. 2013 Jun;38(7):1176-88. doi: 10.1038/npp.2013.12. Epub 2013 Jan 11.

42.

Constitutive knockout of the membrane cytoskeleton protein beta adducin decreases mushroom spine density in the nucleus accumbens but does not prevent spine remodeling in response to cocaine.

Jung Y, Mulholland PJ, Wiseman SL, Chandler LJ, Picciotto MR.

Eur J Neurosci. 2013 Jan;37(1):1-9. doi: 10.1111/ejn.12037. Epub 2012 Oct 29.

43.

Chronic ethanol up-regulates the synaptic expression of the nuclear translational regulatory protein AIDA-1 in primary hippocampal neurons.

Mulholland PJ, Jordan BA, Chandler LJ.

Alcohol. 2012 Sep;46(6):569-76. doi: 10.1016/j.alcohol.2012.04.004. Epub 2012 Jun 14.

44.

Chronic alcohol exposure alters behavioral and synaptic plasticity of the rodent prefrontal cortex.

Kroener S, Mulholland PJ, New NN, Gass JT, Becker HC, Chandler LJ.

PLoS One. 2012;7(5):e37541. doi: 10.1371/journal.pone.0037541. Epub 2012 May 30.

45.

Introduction to Young Investigator Award Symposium: Symposium XII: Young Investigator Award.

Roberto M, Kash TL, Mulholland PJ, Marty VN, Gilpin NW, Walker BM.

Alcohol. 2012 Jun;46(4):301-2. doi: 10.1016/j.alcohol.2012.04.001. Epub 2012 Apr 27. No abstract available.

PMID:
22541586
46.

K(Ca)2 channels: novel therapeutic targets for treating alcohol withdrawal and escalation of alcohol consumption.

Mulholland PJ.

Alcohol. 2012 Jun;46(4):309-15. doi: 10.1016/j.alcohol.2011.11.002. Epub 2012 Mar 30. Review.

47.

Glucocorticoid and polyamine interactions in the plasticity of glutamatergic synapses that contribute to ethanol-associated dependence and neuronal injury.

Prendergast MA, Mulholland PJ.

Addict Biol. 2012 Mar;17(2):209-23. doi: 10.1111/j.1369-1600.2011.00375.x. Epub 2011 Oct 4. Review.

48.

NR2B-deficient mice are more sensitive to the locomotor stimulant and depressant effects of ethanol.

Badanich KA, Doremus-Fitzwater TL, Mulholland PJ, Randall PK, Delpire E, Becker HC.

Genes Brain Behav. 2011 Oct;10(7):805-816. doi: 10.1111/j.1601-183X.2011.00720.x. Epub 2011 Aug 15.

49.

Tolerance to cannabinoid-induced behaviors in mice treated chronically with ethanol.

Pava MJ, Blake EM, Green ST, Mizroch BJ, Mulholland PJ, Woodward JJ.

Psychopharmacology (Berl). 2012 Jan;219(1):137-47. doi: 10.1007/s00213-011-2387-0. Epub 2011 Jun 24.

50.

The glutamatergic component of the mesocortical pathway emanating from different subregions of the ventral midbrain.

Gorelova N, Mulholland PJ, Chandler LJ, Seamans JK.

Cereb Cortex. 2012 Feb;22(2):327-36. doi: 10.1093/cercor/bhr107. Epub 2011 Jun 10.

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