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Items: 1 to 50 of 276

1.

Nanoparticle-Aided Characterization of Arterial Endothelial Architecture during Atherosclerosis Progression and Metabolic Therapy.

Beldman TJ, Malinova TS, Desclos E, Grootemaat AE, Misiak ALS, van der Velden S, van Roomen CPAA, Beckers L, van Veen HA, Krawczyk PM, Hoebe RA, Sluimer JC, Neele AE, de Winther MPJ, van der Wel NN, Lutgens E, Mulder WJM, Huveneers S, Kluza E.

ACS Nano. 2019 Jul 10. doi: 10.1021/acsnano.8b08875. [Epub ahead of print]

PMID:
31268670
2.

Multimodal Positron Emission Tomography Imaging to Quantify Uptake of 89Zr-Labeled Liposomes in the Atherosclerotic Vessel Wall.

Lobatto ME, Binderup T, Robson PM, Giesen LFP, Calcagno C, Witjes J, Fay F, Baxter S, Wessel CH, Eldib M, Bini J, Carlin SD, Stroes ESG, Storm G, Kjaer A, Lewis JS, Reiner T, Fayad ZA, Mulder WJM, Pérez-Medina C.

Bioconjug Chem. 2019 Jun 7. doi: 10.1021/acs.bioconjchem.9b00256. [Epub ahead of print]

PMID:
31095372
3.

Author Correction: Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates.

Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R.

Nat Biomed Eng. 2018 Aug;2(8):623. doi: 10.1038/s41551-018-0281-3.

PMID:
31015637
4.

Therapeutic targeting of trained immunity.

Mulder WJM, Ochando J, Joosten LAB, Fayad ZA, Netea MG.

Nat Rev Drug Discov. 2019 Jul;18(7):553-566. doi: 10.1038/s41573-019-0025-4. Review.

PMID:
30967658
5.

Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates.

Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R.

Nat Biomed Eng. 2018 May;2(5):279-292. doi: 10.1038/s41551-018-0221-2. Epub 2018 Apr 16. Erratum in: Nat Biomed Eng. 2018 Aug;2(8):623.

6.

Accuracy of NGS HLA typing data influenced by STR.

van Deutekom HWM, Mulder W, Rozemuller EH.

Hum Immunol. 2019 Jul;80(7):461-464. doi: 10.1016/j.humimm.2019.03.007. Epub 2019 Mar 26.

PMID:
30926353
7.

Hybrid PET/MR Kernelised Expectation Maximisation Reconstruction for Improved Image-Derived Estimation of the Input Function from the Aorta of Rabbits.

Deidda D, Karakatsanis NA, Robson PM, Calcagno C, Senders ML, Mulder WJM, Fayad ZA, Aykroyd RG, Tsoumpas C.

Contrast Media Mol Imaging. 2019 Jan 16;2019:3438093. doi: 10.1155/2019/3438093. eCollection 2019.

8.

Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance.

Braza MS, van Leent MMT, Lameijer M, Sanchez-Gaytan BL, Arts RJW, Pérez-Medina C, Conde P, Garcia MR, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress RJ, Salem F, Rialdi A, Reiner T, Boros P, Strijkers GJ, Calcagno CC, Ginhoux F, Marazzi I, Lutgens E, Nicolaes GAF, Weber C, Swirski FK, Nahrendorf M, Fisher EA, Duivenvoorden R, Fayad ZA, Netea MG, Mulder WJM, Ochando J.

Immunity. 2018 Nov 20;49(5):819-828.e6. doi: 10.1016/j.immuni.2018.09.008. Epub 2018 Nov 6.

PMID:
30413362
9.

Monocyte and Macrophage Dynamics in the Cardiovascular System: JACC Macrophage in CVD Series (Part 3).

Fayad ZA, Swirski FK, Calcagno C, Robbins CS, Mulder W, Kovacic JC.

J Am Coll Cardiol. 2018 Oct 30;72(18):2198-2212. doi: 10.1016/j.jacc.2018.08.2150. Review.

PMID:
30360828
10.

Imaging Tropoelastin in Atherosclerosis.

Duivenvoorden R, Mulder WJM.

Circ Cardiovasc Imaging. 2018 Aug;11(8):e008147. doi: 10.1161/CIRCIMAGING.118.008147. No abstract available.

11.

Nanoemulsion-Based Delivery of Fluorescent PARP Inhibitors in Mouse Models of Small Cell Lung Cancer.

Gonzales J, Kossatz S, Roberts S, Pirovano G, Brand C, Pérez-Medina C, Donabedian P, de la Cruz MJ, Mulder WJM, Reiner T.

Bioconjug Chem. 2018 Nov 21;29(11):3776-3782. doi: 10.1021/acs.bioconjchem.8b00640. Epub 2018 Nov 7.

12.

Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis.

Senders ML, Hernot S, Carlucci G, van de Voort JC, Fay F, Calcagno C, Tang J, Alaarg A, Zhao Y, Ishino S, Palmisano A, Boeykens G, Meerwaldt AE, Sanchez-Gaytan BL, Baxter S, Zendman L, Lobatto ME, Karakatsanis NA, Robson PM, Broisat A, Raes G, Lewis JS, Tsimikas S, Reiner T, Fayad ZA, Devoogdt N, Mulder WJM, Pérez-Medina C.

JACC Cardiovasc Imaging. 2018 Oct 12. pii: S1936-878X(18)30753-8. doi: 10.1016/j.jcmg.2018.07.027. [Epub ahead of print]

13.

Current and Emerging Preclinical Approaches for Imaging-Based Characterization of Atherosclerosis.

Vigne J, Thackeray J, Essers J, Makowski M, Varasteh Z, Curaj A, Karlas A, Canet-Soulas E, Mulder W, Kiessling F, Schäfers M, Botnar R, Wildgruber M, Hyafil F; Cardiovascular study group of the European Society of Molecular Imaging.

Mol Imaging Biol. 2018 Dec;20(6):869-887. doi: 10.1007/s11307-018-1264-1. Review.

PMID:
30250990
14.

Nanoimmunotherapy to treat ischaemic heart disease.

Duivenvoorden R, Senders ML, van Leent MMT, Pérez-Medina C, Nahrendorf M, Fayad ZA, Mulder WJM.

Nat Rev Cardiol. 2019 Jan;16(1):21-32. doi: 10.1038/s41569-018-0073-1. Review.

PMID:
30209355
15.

Targeting myeloperoxidase in inflammatory atherosclerosis.

Senders ML, Mulder WJM.

Eur Heart J. 2018 Sep 14;39(35):3311-3313. doi: 10.1093/eurheartj/ehy501. No abstract available.

PMID:
30188979
16.

Investigating supramolecular systems using Förster resonance energy transfer.

Teunissen AJP, Pérez-Medina C, Meijerink A, Mulder WJM.

Chem Soc Rev. 2018 Sep 17;47(18):7027-7044. doi: 10.1039/c8cs00278a. Review.

PMID:
30091770
17.

Sonophore-enhanced nanoemulsions for optoacoustic imaging of cancer.

Roberts S, Andreou C, Choi C, Donabedian P, Jayaraman M, Pratt EC, Tang J, Pérez-Medina C, Jason de la Cruz M, Mulder WJM, Grimm J, Kircher M, Reiner T.

Chem Sci. 2018 May 18;9(25):5646-5657. doi: 10.1039/c8sc01706a. eCollection 2018 Jul 7.

18.

Development and Multiparametric Evaluation of Experimental Atherosclerosis in Rabbits.

Senders ML, Lobatto ME, Soler R, Lairez O, Pérez-Medina C, Calcagno C, Fayad ZA, Mulder WJM, Fay F.

Methods Mol Biol. 2018;1816:385-400. doi: 10.1007/978-1-4939-8597-5_30.

PMID:
29987836
19.

Can education improve clinical practice concerning delirium in older hospitalised patients? Results of a pre-test post-test study on an educational intervention for nursing staff.

van Velthuijsen EL, Zwakhalen SMG, Warnier RMJ, Ambergen T, Mulder WJ, Verhey FRJ, Kempen GIJM.

BMC Med Educ. 2018 Apr 2;18(1):59. doi: 10.1186/s12909-018-1177-3.

20.

Reversible Electroporation-Mediated Liposomal Doxorubicin Delivery to Tumors Can Be Monitored With 89Zr-Labeled Reporter Nanoparticles.

Srimathveeravalli G, Abdel-Atti D, Pérez-Medina C, Takaki H, Solomon SB, Mulder WJM, Reiner T.

Mol Imaging. 2018 Jan-Dec;17:1536012117749726. doi: 10.1177/1536012117749726.

21.

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.

Seijkens TTP, van Tiel CM, Kusters PJH, Atzler D, Soehnlein O, Zarzycka B, Aarts SABM, Lameijer M, Gijbels MJ, Beckers L, den Toom M, Slütter B, Kuiper J, Duchene J, Aslani M, Megens RTA, van 't Veer C, Kooij G, Schrijver R, Hoeksema MA, Boon L, Fay F, Tang J, Baxter S, Jongejan A, Moerland PD, Vriend G, Bleijlevens B, Fisher EA, Duivenvoorden R, Gerdes N, de Winther MPJ, Nicolaes GA, Mulder WJM, Weber C, Lutgens E.

J Am Coll Cardiol. 2018 Feb 6;71(5):527-542. doi: 10.1016/j.jacc.2017.11.055.

22.

Effects of a Medication Review on Delirium in Older Hospitalised Patients: A Comparative Retrospective Cohort Study.

van Velthuijsen EL, Zwakhalen SMG, Pijpers E, van de Ven LI, Ambergen T, Mulder WJ, Verhey FRJ, Kempen GIJM.

Drugs Aging. 2018 Feb;35(2):153-161. doi: 10.1007/s40266-018-0523-9.

23.

PET/MR Imaging of Malondialdehyde-Acetaldehyde Epitopes With a Human Antibody Detects Clinically Relevant Atherothrombosis.

Senders ML, Que X, Cho YS, Yeang C, Groenen H, Fay F, Calcagno C, Meerwaldt AE, Green S, Miu P, Lobatto ME, Reiner T, Fayad ZA, Witztum JL, Mulder WJM, Pérez-Medina C, Tsimikas S.

J Am Coll Cardiol. 2018 Jan 23;71(3):321-335. doi: 10.1016/j.jacc.2017.11.036.

24.

Neutrophil derived CSF1 induces macrophage polarization and promotes transplantation tolerance.

Braza MS, Conde P, Garcia M, Cortegano I, Brahmachary M, Pothula V, Fay F, Boros P, Werner SA, Ginhoux F, Mulder WJM, Ochando J.

Am J Transplant. 2018 May;18(5):1247-1255. doi: 10.1111/ajt.14645. Epub 2018 Feb 7.

25.

High-Density Lipoprotein Nanobiologics for Precision Medicine.

Mulder WJM, van Leent MMT, Lameijer M, Fisher EA, Fayad ZA, Pérez-Medina C.

Acc Chem Res. 2018 Jan 16;51(1):127-137. doi: 10.1021/acs.accounts.7b00339. Epub 2017 Dec 27. Review.

PMID:
29281244
26.

RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions.

Hogstad B, Berres ML, Chakraborty R, Tang J, Bigenwald C, Serasinghe M, Lim KPH, Lin H, Man TK, Remark R, Baxter S, Kana V, Jordan S, Karoulia Z, Kwan WH, Leboeuf M, Brandt E, Salmon H, McClain K, Poulikakos P, Chipuk J, Mulder WJM, Allen CE, Merad M.

J Exp Med. 2018 Jan 2;215(1):319-336. doi: 10.1084/jem.20161881. Epub 2017 Dec 20.

27.

The use of an electronic clinical rule to discontinue chronically used benzodiazepines and related Z drugs.

Mestres Gonzalvo C, Milosevic V, van Oijen BPC, de Wit HAJM, Hurkens KPGM, Mulder WJ, Janknegt R, Schols JMGA, Verhey FR, Winkens B, van der Kuy PHM.

Eur J Clin Pharmacol. 2018 Feb;74(2):227-231. doi: 10.1007/s00228-017-2369-1. Epub 2017 Nov 10.

PMID:
29127459
28.

Validation of an automated delirium prediction model (DElirium MOdel (DEMO)): an observational study.

Mestres Gonzalvo C, de Wit HAJM, van Oijen BPC, Deben DS, Hurkens KPGM, Mulder WJ, Janknegt R, Schols JMGA, Verhey FR, Winkens B, van der Kuy PM.

BMJ Open. 2017 Nov 8;7(11):e016654. doi: 10.1136/bmjopen-2017-016654.

29.

Cardiovascular Immunotherapy and the Role of Imaging.

Zupančič E, Fayad ZA, Mulder WJM.

Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):e167-e171. doi: 10.1161/ATVBAHA.117.309227. Review. No abstract available.

30.

Specific Binding of Liposomal Nanoparticles through Inverse Electron-Demand Diels-Alder Click Chemistry.

Brand C, Iacono P, Pérez-Medina C, Mulder WJM, Kircher MF, Reiner T.

ChemistryOpen. 2017 Aug 7;6(5):615-619. doi: 10.1002/open.201700105. eCollection 2017 Oct.

31.

Integrating nanomedicine and imaging.

Pérez-Medina C, Hak S, Reiner T, Fayad ZA, Nahrendorf M, Mulder WJM.

Philos Trans A Math Phys Eng Sci. 2017 Nov 28;375(2107). pii: 20170110. doi: 10.1098/rsta.2017.0110. Review.

32.

The Maastricht Frailty Screening Tool for Hospitalised Patients (MFST-HP) to Identify Non-Frail Patients.

Warnier RMJ, van Rossum E, van Kuijk SMJ, Mulder WJ, Schols JMGA, Kempen GIJM.

Int J Clin Pract. 2017 Sep;71(9). doi: 10.1111/ijcp.13003. Epub 2017 Sep 8.

PMID:
28885763
33.

Cancer Immunotherapy: From local to global.

Mulder WJM, Gnjatic S.

Nat Nanotechnol. 2017 Sep 6;12(9):840-841. doi: 10.1038/nnano.2017.196. No abstract available.

PMID:
28875982
34.

A systematic comparison of clinically viable nanomedicines targeting HMG-CoA reductase in inflammatory atherosclerosis.

Alaarg A, Senders ML, Varela-Moreira A, Pérez-Medina C, Zhao Y, Tang J, Fay F, Reiner T, Fayad ZA, Hennink WE, Metselaar JM, Mulder WJM, Storm G.

J Control Release. 2017 Sep 28;262:47-57. doi: 10.1016/j.jconrel.2017.07.013. Epub 2017 Jul 9.

35.

Medical Advice for Sick-reported Students (MASS) in intermediate vocational education schools: design of a controlled before-and-after study.

Van der Vlis MK, Lugtenberg M, Vanneste YTM, Berends W, Mulder W, Bannink R, Van Grieken A, Raat H, de Kroon MLA.

BMC Public Health. 2017 Jun 29;17(1):608. doi: 10.1186/s12889-017-4530-2.

36.

A new tool for rapid and reliable diagnosis of HLA loss relapses after HSCT.

Ahci M, Toffalori C, Bouwmans E, Crivello P, Brambati C, Pultrone C, Stempelmann K, Bost D, Mazzi B, Beelen DW, Ciceri F, Mulder W, Fleischhauer K, Vago L.

Blood. 2017 Sep 7;130(10):1270-1273. doi: 10.1182/blood-2017-05-784306. Epub 2017 Jun 27. No abstract available.

37.

Energy consumption and water-soluble protein release by cell wall disruption of Nannochloropsis gaditana.

Safi C, Cabas Rodriguez L, Mulder WJ, Engelen-Smit N, Spekking W, van den Broek LAM, Olivieri G, Sijtsma L.

Bioresour Technol. 2017 Sep;239:204-210. doi: 10.1016/j.biortech.2017.05.012. Epub 2017 May 5.

38.

Applying nanomedicine in maladaptive inflammation and angiogenesis.

Alaarg A, Pérez-Medina C, Metselaar JM, Nahrendorf M, Fayad ZA, Storm G, Mulder WJM.

Adv Drug Deliv Rev. 2017 Sep 15;119:143-158. doi: 10.1016/j.addr.2017.05.009. Epub 2017 May 12. Review.

39.

Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis.

Beldman TJ, Senders ML, Alaarg A, Pérez-Medina C, Tang J, Zhao Y, Fay F, Deichmöller J, Born B, Desclos E, van der Wel NN, Hoebe RA, Kohen F, Kartvelishvily E, Neeman M, Reiner T, Calcagno C, Fayad ZA, de Winther MPJ, Lutgens E, Mulder WJM, Kluza E.

ACS Nano. 2017 Jun 27;11(6):5785-5799. doi: 10.1021/acsnano.7b01385. Epub 2017 May 15.

40.

Investigating the Cellular Specificity in Tumors of a Surface-Converting Nanoparticle by Multimodal Imaging.

Fay F, Hansen L, Hectors SJCG, Sanchez-Gaytan BL, Zhao Y, Tang J, Munitz J, Alaarg A, Braza MS, Gianella A, Aaronson SA, Reiner T, Kjems J, Langer R, Hoeben FJM, Janssen HM, Calcagno C, Strijkers GJ, Fayad ZA, Pérez-Medina C, Mulder WJM.

Bioconjug Chem. 2017 May 17;28(5):1413-1421. doi: 10.1021/acs.bioconjchem.7b00086. Epub 2017 May 5.

41.

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines.

Tang J, Pérez-Medina C, Zhao Y, Sadique A, Mulder WJ, Reiner T.

J Vis Exp. 2017 Mar 4;(121). doi: 10.3791/55271.

42.

A Licence to Prescribe.

Kramers C, Janssen BJ, Knol W, Hessel MHM, Mulder WM, Dumont G, Maassen van den Brink A, Tichelaar J.

Br J Clin Pharmacol. 2017 Aug;83(8):1860-1861. doi: 10.1111/bcp.13257. Epub 2017 Mar 2. No abstract available.

43.

Detection and management of hyperactive and hypoactive delirium in older patients during hospitalization: a retrospective cohort study evaluating daily practice.

van Velthuijsen EL, Zwakhalen SMG, Mulder WJ, Verhey FRJ, Kempen GIJM.

Int J Geriatr Psychiatry. 2018 Nov;33(11):1521-1529. doi: 10.1002/gps.4690. Epub 2017 Feb 14.

44.

Supporting clinical rules engine in the adjustment of medication (SCREAM): protocol of a multicentre, prospective, randomised study.

Mestres Gonzalvo C, de Wit HA, van Oijen BP, Hurkens KP, Janknegt R, Schols JM, Mulder WJ, Verhey FR, Winkens B, van der Kuy PM.

BMC Geriatr. 2017 Jan 26;17(1):35. doi: 10.1186/s12877-017-0426-3.

45.

Real-Time Monitoring of Nanoparticle Formation by FRET Imaging.

Sanchez-Gaytan BL, Fay F, Hak S, Alaarg A, Fayad ZA, Pérez-Medina C, Mulder WJ, Zhao Y.

Angew Chem Int Ed Engl. 2017 Mar 6;56(11):2923-2926. doi: 10.1002/anie.201611288. Epub 2017 Jan 23.

46.

Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.

Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M.

Nat Commun. 2017 Jan 16;8:14064. doi: 10.1038/ncomms14064.

47.

Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study.

Tawakol A, Ishai A, Takx RA, Figueroa AL, Ali A, Kaiser Y, Truong QA, Solomon CJ, Calcagno C, Mani V, Tang CY, Mulder WJ, Murrough JW, Hoffmann U, Nahrendorf M, Shin LM, Fayad ZA, Pitman RK.

Lancet. 2017 Feb 25;389(10071):834-845. doi: 10.1016/S0140-6736(16)31714-7. Epub 2017 Jan 12. Erratum in: Lancet. 2017 Feb 25;389(10071):804. Lancet. 2017 Feb 25;389(10071):804.

PMID:
28088338
48.

Near-Infrared Quantum Dot and 89Zr Dual-Labeled Nanoparticles for in Vivo Cerenkov Imaging.

Zhao Y, Shaffer TM, Das S, Pérez-Medina C, Mulder WJ, Grimm J.

Bioconjug Chem. 2017 Feb 15;28(2):600-608. doi: 10.1021/acs.bioconjchem.6b00687. Epub 2017 Jan 12.

49.

Biorefinery of microalgal soluble proteins by sequential processing and membrane filtration.

Safi C, Olivieri G, Campos RP, Engelen-Smit N, Mulder WJ, van den Broek LAM, Sijtsma L.

Bioresour Technol. 2017 Feb;225:151-158. doi: 10.1016/j.biortech.2016.11.068. Epub 2016 Nov 18.

50.

Imaging-guided revival of nanomedicine?

Senders ML, Fayad ZA, Reiner T, Mulder WJ, Pérez-Medina C.

Nanomedicine (Lond). 2017 Jan;12(2):89-90. Epub 2016 Nov 23. No abstract available.

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