Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 220

1.

Long-term treatment with recombinant human pentraxin 2 protein in patients with idiopathic pulmonary fibrosis: an open-label extension study.

Raghu G, van den Blink B, Hamblin MJ, Brown AW, Golden JA, Ho LA, Wijsenbeek MS, Vasakova M, Pesci A, Antin-Ozerkis DE, Meyer KC, Kreuter M, Moran D, Santin-Janin H, Aubin F, Mulder GJ, Gupta R, Richeldi L.

Lancet Respir Med. 2019 Aug;7(8):657-664. doi: 10.1016/S2213-2600(19)30172-9. Epub 2019 May 20.

PMID:
31122893
2.

Effect of Recombinant Human Pentraxin 2 vs Placebo on Change in Forced Vital Capacity in Patients With Idiopathic Pulmonary Fibrosis: A Randomized Clinical Trial.

Raghu G, van den Blink B, Hamblin MJ, Brown AW, Golden JA, Ho LA, Wijsenbeek MS, Vasakova M, Pesci A, Antin-Ozerkis DE, Meyer KC, Kreuter M, Santin-Janin H, Mulder GJ, Bartholmai B, Gupta R, Richeldi L.

JAMA. 2018 Jun 12;319(22):2299-2307. doi: 10.1001/jama.2018.6129.

3.

Reply to letter to the editor.

de Ree H, van den Berg M, Brand T, Mulder GJ, Simons R, Veldhuijzen van Zanten B, Westerink RH.

Neurotoxicology. 2015 Jan;46:167-8. doi: 10.1016/j.neuro.2014.12.014. Epub 2015 Jan 13. No abstract available.

PMID:
25595098
4.

Health risk assessment of exposure to TriCresyl Phosphates (TCPs) in aircraft: a commentary.

de Ree H, van den Berg M, Brand T, Mulder GJ, Simons R, Veldhuijzen van Zanten B, Westerink RH.

Neurotoxicology. 2014 Dec;45:209-15. doi: 10.1016/j.neuro.2014.08.011. Epub 2014 Sep 3.

PMID:
25193069
5.

Acquiring orphans.

Rooswinkel R, Mulder GJ, van Deventer S.

Nat Biotechnol. 2014 Mar;32(3):213-6. doi: 10.1038/nbt.2836. No abstract available.

PMID:
24727767
6.

Building for big pharma.

Giniatullina A, Boorsma M, Mulder GJ, van Deventer S.

Nat Biotechnol. 2013 Apr;31(4):284-7. No abstract available.

PMID:
23563416
7.

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia.

Cavazzana-Calvo M, Payen E, Negre O, Wang G, Hehir K, Fusil F, Down J, Denaro M, Brady T, Westerman K, Cavallesco R, Gillet-Legrand B, Caccavelli L, Sgarra R, Maouche-Chrétien L, Bernaudin F, Girot R, Dorazio R, Mulder GJ, Polack A, Bank A, Soulier J, Larghero J, Kabbara N, Dalle B, Gourmel B, Socie G, Chrétien S, Cartier N, Aubourg P, Fischer A, Cornetta K, Galacteros F, Beuzard Y, Gluckman E, Bushman F, Hacein-Bey-Abina S, Leboulch P.

Nature. 2010 Sep 16;467(7313):318-22. doi: 10.1038/nature09328.

8.

Pharmacokinetic and pharmacodynamic evaluation of liposomal amikacin for inhalation in cystic fibrosis patients with chronic pseudomonal infection.

Okusanya OO, Bhavnani SM, Hammel J, Minic P, Dupont LJ, Forrest A, Mulder GJ, Mackinson C, Ambrose PG, Gupta R.

Antimicrob Agents Chemother. 2009 Sep;53(9):3847-54. doi: 10.1128/AAC.00872-08. Epub 2009 May 18.

9.

[Selective serotonin reuptake inhibitors (SSRI's) are not indicated for children and adolescents with depression].

Lekkerkerker JF, Schobben AF, van Dissel JT, Hekster YA, Hoes AW, Mulder GJ, Neef C, Peeters MF, van Ree JM, Rosmalen CF, Schellekens H, Schellens JH, Silberbusch J.

Ned Tijdschr Geneeskd. 2005 Aug 13;149(33):1870-1; author reply 1871-2. Dutch. No abstract available.

PMID:
16128186
10.

Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.

Huber WW, Teitel CH, Coles BF, King RS, Wiese FW, Kaderlik KR, Casciano DA, Shaddock JG, Mulder GJ, Ilett KF, Kadlubar FF.

Environ Mol Mutagen. 2004;44(4):265-76.

PMID:
15468054
11.

Isolated hepatic perfusion for the treatment of colorectal metastases confined to the liver: recent trends and perspectives.

Rothbarth J, Tollenaar RA, Schellens JH, Nortier JW, Kool LJ, Kuppen PJ, Mulder GJ, van de Velde CJ.

Eur J Cancer. 2004 Aug;40(12):1812-24. Review.

PMID:
15288282
12.

Immunohistochemical detection of melphalan-DNA adducts in colon cancer cells in vitro and human colorectal liver tumours in vivo.

Rothbarth J, Koevoets C, Tollenaar RA, Tilby MJ, van de Velde CJ, Mulder GJ, Kuppen PJ.

Biochem Pharmacol. 2004 May 1;67(9):1771-8.

PMID:
15081876
13.

Rat colon carcinoma cells that survived systemic immune surveillance are less sensitive to NK-cell mediated apoptosis.

Velthuis JH, Stitzinger M, Aalbers RI, de Bont HJ, Mulder GJ, Kuppen PJ, Nagelkerke JF.

Clin Exp Metastasis. 2003;20(8):713-21.

PMID:
14713105
14.

Bcl-2 overexpression does not prevent but retards adriamycin toxicity in CC531 colon carcinoma cells.

Hoetelmans RW, Vahrmeijer AL, Mulder GJ, van de Velde CJ, Nagelkerke JF, van Dierendonck JH.

Chemotherapy. 2003 Dec;49(6):309-15.

PMID:
14671432
15.

An experimental minimally invasive perfusion technique for the treatment of liver metastases.

Rothbarth J, Pijl ME, Tollenaar RA, Tijl F, Ivancev G, Mulder GJ, Kuppen PJ, van de Velde CJ, Schultze Kool LJ.

Eur J Surg Oncol. 2003 Nov;29(9):757-63.

PMID:
14602496
16.

Simple high-performance liquid chromatographic assay for melphalan in perfusate, rat liver and tumour tissue.

Sparidans RW, Silvertand L, Dost F, Rothbarth J, Mulder GJ, Schellens JH, Beijnen JH.

Biomed Chromatogr. 2003 Oct;17(7):458-64.

PMID:
14598330
17.

Interleukin-2 activated NK cells do not use the CD95L- and TRAIL-pathways in the rapid induction of apoptosis of rat colon carcinoma CC531s cells.

Velthuis JH, de Bont HJ, Medema JP, Kuppen PJ, Mulder GJ, Nagelkerke JF.

Immunobiology. 2003;207(2):115-27.

PMID:
12675269
18.

Melphalan antitumor efficacy and hepatotoxicity: the effect of variable infusion duration in the hepatic artery.

Rothbarth J, Woutersen RA, Sparidans RW, van de Velde CJ, Mulder GJ.

J Pharmacol Exp Ther. 2003 Jun;305(3):1098-103. Epub 2003 Feb 20.

PMID:
12606622
19.

The role of various Bcl-2 domains in the anti-proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain.

Hoetelmans RW, Vahrmeijer AL, van Vlierberghe RL, Keijzer R, van de Velde CJ, Mulder GJ, Van Dierendonck JH.

Cell Prolif. 2003 Feb;36(1):35-44.

PMID:
12558659
21.

Inhibition of the multidrug resistance protein 1 (MRP1) by peptidomimetic glutathione-conjugate analogs.

Burg D, Wielinga P, Zelcer N, Saeki T, Mulder GJ, Borst P.

Mol Pharmacol. 2002 Nov;62(5):1160-6.

PMID:
12391280
22.

Reduced liver uptake of arterially infused melphalan during retrograde rat liver perfusion with unaffected liver tumor uptake.

Rothbarth J, Sparidans RW, Beijnen JH, Schultze-Kool LJ, Putter H, van de Velde CJ, Mulder GJ.

J Pharmacol Exp Ther. 2002 Nov;303(2):736-40.

PMID:
12388659
23.

Differential regulation of doxorubicin-induced mitochondrial dysfunction and apoptosis by Bcl-2 in mammary adenocarcinoma (MTLn3) cells.

Huigsloot M, Tijdens IB, Mulder GJ, van de Water B.

J Biol Chem. 2002 Sep 27;277(39):35869-79. Epub 2002 Jul 9.

24.

The role of calpains in apoptotic changes in isolated hepatocytes after attack by Natural Killer cells.

Blom WM, de Bont HJ, Mulder GJ, Nagelkerke JF.

Environ Toxicol Pharmacol. 2002 Jul;11(3-4):159-65.

PMID:
21782598
25.

Modulation of cytostatic efficacy of melphalan by glutathione: mechanisms and efficacy.

Rothbarth J, Vahrmeijer AL, Mulder GJ.

Chem Biol Interact. 2002 May 20;140(2):93-107. Review. No abstract available.

PMID:
12076518
26.

Inhibition of glutathione S-transferase in rat hepatocytes by a glycine-tetrazole modified S-alkyl-GSH analogue.

Burg D, Hameetman L, Filippov DV, van der Marel GA, Mulder GJ.

Bioorg Med Chem Lett. 2002 Jun 17;12(12):1579-82.

PMID:
12039566
27.

Distinct intracellular signaling in tumor necrosis factor-related apoptosis-inducing ligand- and CD95 ligand-mediated apoptosis.

Velthuis JH, Rouschop KM, De Bont HJ, Mulder GJ, Nagelkerke JF.

J Biol Chem. 2002 Jul 5;277(27):24631-7. Epub 2002 Apr 29.

28.

Apoptosis induced by extracellular ATP in the mouse neuroblastoma cell line N1E-115: studies on involvement of P2 receptors and adenosine.

Schrier SM, Florea BI, Mulder GJ, Nagelkerke JF, IJzerman AP.

Biochem Pharmacol. 2002 Mar 15;63(6):1119-26.

PMID:
11931844
29.

Adenosine-induced caspase activity in N1E-115 cells.

Schier SM, Ijzerman AP, Mulder GJ, Nagelkerke JF.

Adv Exp Med Biol. 2000;486:223-6. No abstract available.

PMID:
11783488
30.

Peptidomimetic glutathione analogues as novel gammaGT stable GST inhibitors.

Burg D, Filippov DV, Hermanns R, van der Marel GA, van Boom JH, Mulder GJ.

Bioorg Med Chem. 2002 Jan;10(1):195-205.

PMID:
11738622
31.
32.

Remodeling of the actin cytoskeleton of target hepatocytes and NK cells during induction of apoptosis.

Blom WM, de Bont HJ, Meijerman I, Kuppen PJ, van Der Meulen H, Mulder GJ, Nagelkerke JF.

Cell Motil Cytoskeleton. 2001 Jun;49(2):78-92.

PMID:
11443738
33.

Extracellular adenosine-induced apoptosis in mouse neuroblastoma cells: studies on involvement of adenosine receptors and adenosine uptake.

Schrier SM, van Tilburg EW, van der Meulen H, Ijzerman AP, Mulder GJ, Nagelkerke JF.

Biochem Pharmacol. 2001 Feb 15;61(4):417-25.

PMID:
11226375
34.

Loss of nuclear p53 protein in preneoplastic rat hepatocytes is accompanied by Mdm2 and Bcl-2 overexpression and by defective response to DNA damage in vivo.

Van Gijssel HE, Ohlson LC, Torndal UB, Mulder GJ, Eriksson LC, Porsch-Hällström I, Meerman JH.

Hepatology. 2000 Oct;32(4 Pt 1):701-10.

PMID:
11003613
35.

Cytotoxicity and biotransformation of the anticancer drug perillyl alcohol in PC12 cells and in the rat.

Boon PJ, van der Boon D, Mulder GJ.

Toxicol Appl Pharmacol. 2000 Aug 15;167(1):55-62.

PMID:
10936079
36.

Cleavage of the actin-capping protein alpha -adducin at Asp-Asp-Ser-Asp633-Ala by caspase-3 is preceded by its phosphorylation on serine 726 in cisplatin-induced apoptosis of renal epithelial cells.

van de Water B, Tijdens IB, Verbrugge A, Huigsloot M, Dihal AA, Stevens JL, Jaken S, Mulder GJ.

J Biol Chem. 2000 Aug 18;275(33):25805-13.

37.

Development of resistance to glutathione depletion-induced cell death in CC531 colon carcinoma cells: association with increased expression of bcl-2.

Vahrmeijer AL, Hoetelmans RW, Mulder GJ, Schutrups J, van Vlierberghe RL, van de Velde CJ, van Dierendonck JH.

Biochem Pharmacol. 2000 Jun 15;59(12):1557-62.

PMID:
10799652
38.

Increased local cytostatic drug exposure by isolated hepatic perfusion: a phase I clinical and pharmacologic evaluation of treatment with high dose melphalan in patients with colorectal cancer confined to the liver.

Vahrmeijer AL, van Dierendonck JH, Keizer HJ, Beijnen JH, Tollenaar RA, Pijl ME, Marinelli A, Kuppen PJ, van Bockel JH, Mulder GJ, van de Velde CJ.

Br J Cancer. 2000 May;82(9):1539-46.

39.
40.

Prevention of cycloheximide-induced apoptosis in hepatocytes by adenosine and by caspase inhibitors.

Blom WM, de Bont HJ, Meijerman I, Mulder GJ, Nagelkerke JF.

Biochem Pharmacol. 1999 Dec 15;58(12):1891-8.

PMID:
10591143
42.

Glutathione conjugation of 4-hydroxy-trans-2,3-nonenal in the rat in vivo, the isolated perfused liver and erythrocytes.

Boon PJ, Marinho HS, Oosting R, Mulder GJ.

Toxicol Appl Pharmacol. 1999 Sep 15;159(3):214-23.

PMID:
10486308
43.

Effect of glutathione depletion on inhibition of cell cycle progression and induction of apoptosis by melphalan (L-phenylalanine mustard) in human colorectal cancer cells.

Vahrmeijer AL, van Dierendonck JH, Schutrups J, van de Velde CJ, Mulder GJ.

Biochem Pharmacol. 1999 Aug 15;58(4):655-64.

PMID:
10413303
45.

Cisplatin effects on F-actin and matrix proteins precede renal tubular cell detachment and apoptosis in vitro.

Kruidering M, van de Water B, Zhan Y, Baelde JJ, Heer E, Mulder GJ, Stevens JL, Nagelkerke JF.

Cell Death Differ. 1998 Jul;5(7):601-14.

46.
47.

Interleukin-2-activated natural killer cells can induce both apoptosis and necrosis in rat hepatocytes.

Blom WM, De Bont HJ, Meijerman I, Kuppen PJ, Mulder GJ, Nagelkerke JF.

Hepatology. 1999 Mar;29(3):785-92.

PMID:
10051480
48.

Inhibition of glutathione conjugation in the rat in vivo by analogues of glutathione conjugates.

Ouwerkerk-Mahadevan S, Mulder GJ.

Chem Biol Interact. 1998 Apr 24;111-112:163-76.

PMID:
9679552
50.

Nuclear accumulation of G-actin in isolated rat hepatocytes by adenine nucleotides.

Meijerman I, Blom WM, de Bont HJ, Mulder GJ, Nagelkerke JF.

Biochem Biophys Res Commun. 1997 Nov 26;240(3):697-700.

PMID:
9398629

Supplemental Content

Loading ...
Support Center