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Hepatic stearoyl CoA desaturase 1 deficiency increases glucose uptake in adipose tissue partially through the PGC-1α-FGF21 axis in mice.

AlJohani A, Khan MI, Bonneville A, Guo C, Jeffery J, O'Neill L, Syed DN, Lewis SA, Burhans M, Mukhtar H, Ntambi JM.

J Biol Chem. 2019 Nov 5. pii: jbc.RA119.009868. doi: 10.1074/jbc.RA119.009868. [Epub ahead of print]


Relative Abundance of Ammonia Oxidizing Archaea and Bacteria Influences Soil Nitrification Responses to Temperature.

Mukhtar H, Lin YP, Lin CM, Lin YR.

Microorganisms. 2019 Nov 4;7(11). pii: E526. doi: 10.3390/microorganisms7110526.


Hepatic Stearoyl-CoA desaturase-1 deficiency-mediated activation of mTORC1- PGC-1α axis regulates ER stress during high-carbohydrate feeding.

Aljohani A, Khan MI, Syed DN, Abram B, Lewis S, Neill LO, Mukhtar H, Ntambi JM.

Sci Rep. 2019 Oct 31;9(1):15761. doi: 10.1038/s41598-019-52339-7.


Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models.

Chamcheu JC, Esnault S, Adhami VM, Noll AL, Banang-Mbeumi S, Roy T, Singh SS, Huang S, Kousoulas KG, Mukhtar H.

Cells. 2019 Sep 15;8(9). pii: E1089. doi: 10.3390/cells8091089.


Assessing thermodynamic parameter sensitivity for simulating temperature responses of soil nitrification.

Mukhtar H, Lin YP, Lin CM, Petway JR.

Environ Sci Process Impacts. 2019 Sep 18;21(9):1596-1608. doi: 10.1039/c9em00310j.


Recovery of reproductive function of female zebrafish from the toxic effects of microcystin-LR exposure.

Kawan A, Zhang T, Liu W, Mukhtar H, Zhan C, Zhang X.

Aquat Toxicol. 2019 Sep;214:105240. doi: 10.1016/j.aquatox.2019.105240. Epub 2019 Jul 5.


Antioxidant activity, α-glucosidase inhibition and phytochemical profiling of Hyophorbe lagenicaulis leaf extracts.

William J, John P, Mumtaz MW, Ch AR, Adnan A, Mukhtar H, Sharif S, Raza SA, Akhtar MT.

PeerJ. 2019 Jun 20;7:e7022. doi: 10.7717/peerj.7022. eCollection 2019.


Cyclic peptide: a safe and effective alternative to synthetic aflatoxin B1-competitive antigens.

Mukhtar H, Ma L, Pang Q, Zhou Y, Wang X, Xu T, Hammock BD, Wang J.

Anal Bioanal Chem. 2019 Jul;411(17):3881-3890. doi: 10.1007/s00216-019-01862-7. Epub 2019 May 31.


Metabolite profiling of Cycas revoluta leaf extract and docking studies on alpha-glucosidase inhibitory molecular targets by phytochemicals.

Arshad M, Mumtaz MW, Chaudhary AR, Rashid U, Ali M, Mukhtar H, Adnan A, Raza SA.

Pak J Pharm Sci. 2019 Mar;32(2 (Supplementary)):871-874.


Probing the Performance of Glucose Oxidase Treated Graphene-Based Field Effect Transistors.

Siddique S, Mukhtar H.

J Nanosci Nanotechnol. 2019 Nov 1;19(11):7442-7446. doi: 10.1166/jnn.2019.16723.


Fisetin and 5-fluorouracil: Effective combination for PIK3CA-mutant colorectal cancer.

Khan N, Jajeh F, Eberhardt EL, Miller DD, Albrecht DM, Van Doorn R, Hruby MD, Maresh ME, Clipson L, Mukhtar H, Halberg RB.

Int J Cancer. 2019 Dec 1;145(11):3022-3032. doi: 10.1002/ijc.32367. Epub 2019 May 10.


Assessing the relative importance of social determinants of health in malaria and anemia classification based on machine learning techniques.

Sow B, Mukhtar H, Ahmad HF, Suguri H.

Inform Health Soc Care. 2019 Mar 27:1-13. doi: 10.1080/17538157.2019.1582056. [Epub ahead of print]


Investigation of antiplasmodial efficacy of lupeol and ursolic acid isolated from Ficus benjamina leaves extract.

Singh A, Mukhtar HM, Kaur H, Kaur L.

Nat Prod Res. 2019 Jan 2:1-4. doi: 10.1080/14786419.2018.1540476. [Epub ahead of print]


Antioxidant activity, Hypoglycemic potential and metabolite profiling of Hyophorbe indica leaf extract.

William J, John P, Mumtaz MW, Ch AR, Adnan A, Mukhtar H, Sharif S, Raza SA.

Pak J Pharm Sci. 2018 Nov;31(6 (Supplementary):2737-2742.


Tea Polyphenols in Promotion of Human Health.

Khan N, Mukhtar H.

Nutrients. 2018 Dec 25;11(1). pii: E39. doi: 10.3390/nu11010039. Review.


Development and validation of RP-HPLC method for the determination of stigmasterol in the botanical extract of Ficus deltoidea.

Mukhtar HM, Singh A, Soni V, Singh A, Kaur H.

Nat Prod Res. 2019 Oct;33(19):2868-2872. doi: 10.1080/14786419.2018.1503661. Epub 2018 Nov 23.


AKT Inhibition Modulates H3K4 Demethylase Levels in PTEN-Null Prostate Cancer.

Khan MI, Hamid A, Rath S, Ateeq B, Khan Q, Siddiqui IA, Adhami VM, Choudhry H, Zamzami MA, Mukhtar H.

Mol Cancer Ther. 2019 Feb;18(2):356-363. doi: 10.1158/1535-7163.MCT-18-0141. Epub 2018 Nov 16.


Purification and Characterization of a Thermostable Cellobiohydrolase from Thermotoga petrophila.

Haq IU, Tahir SF, Aftab MN, Akram F, Asad-Ur-Rehman, Nawaz A, Mukhtar H.

Protein Pept Lett. 2018;25(11):1003-1014. doi: 10.2174/0929866525666181108101824.


Proproliferative function of adaptor protein GRB10 in prostate carcinoma.

Khan MI, Al Johani A, Hamid A, Ateeq B, Manzar N, Adhami VM, Lall RK, Rath S, Sechi M, Siddiqui IA, Choudhry H, Zamzami MA, Havighurst TC, Huang W, Ntambi JM, Mukhtar H.

FASEB J. 2019 Mar;33(3):3198-3211. doi: 10.1096/fj.201800265RR. Epub 2018 Oct 31.


Fisetin targets YB-1/RSK axis independent of its effect on ERK signaling: insights from in vitro and in vivo melanoma models.

Sechi M, Lall RK, Afolabi SO, Singh A, Joshi DC, Chiu SY, Mukhtar H, Syed DN.

Sci Rep. 2018 Oct 24;8(1):15726. doi: 10.1038/s41598-018-33879-w.


India-United States Dialogue on Traditional Medicine: Toward Collaborative Research and Generation of an Evidence Base.

White JD, O'Keefe BR, Sharma J, Javed G, Nukala V, Ganguly A, Khan IA, Kumar NB, Mukhtar H, Pauli GF, Walker L, Sivaram S, Rajaraman P, Trimble EL.

J Glob Oncol. 2018 Sep;4:1-10. doi: 10.1200/JGO.17.00099. Epub 2017 Nov 16. Review.


ST-elevation myocardial infarction in a migrant population: a registry-based study of patient treatment and outcomes.

Rye E, Lee A, Mukhtar H, Narayan A, Robert Denniss A, Chow C, Kovoor P, Sivagangabalan G.

Intern Med J. 2019 Apr;49(4):502-512. doi: 10.1111/imj.14084.


Chitosan-based nanoformulated (-)-epigallocatechin-3-gallate (EGCG) modulates human keratinocyte-induced responses and alleviates imiquimod-induced murine psoriasiform dermatitis.

Chamcheu JC, Siddiqui IA, Adhami VM, Esnault S, Bharali DJ, Babatunde AS, Adame S, Massey RJ, Wood GS, Longley BJ, Mousa SA, Mukhtar H.

Int J Nanomedicine. 2018 Jul 20;13:4189-4206. doi: 10.2147/IJN.S165966. eCollection 2018.


Nummularic acid, a triterpenoid, from the medicinal plant Fraxinus xanthoxyloides, induces energy crisis to suppress growth of prostate cancer cells.

Younis T, Khan MI, Khan MR, Rasul A, Majid M, Adhami VM, Mukhtar H.

Mol Carcinog. 2018 Oct;57(10):1267-1277. doi: 10.1002/mc.22841. Epub 2018 Jun 5.


Targeting epithelial to mesenchymal transition in prostate cancer by a novel compound, plectranthoic acid, isolated from Ficus microcarpa.

Akhtar N, Syed DN, Lall RK, Mirza B, Mukhtar H.

Mol Carcinog. 2018 May;57(5):653-663. doi: 10.1002/mc.22790. Epub 2018 Feb 27.


VHH Antibodies: Reagents for Mycotoxin Detection in Food Products.

Wang J, Mukhtar H, Ma L, Pang Q, Wang X.

Sensors (Basel). 2018 Feb 6;18(2). pii: E485. doi: 10.3390/s18020485. Review.


Risk factors associated with metabolic syndrome and cardiovascular disease among women with polycystic ovary syndrome in Tabuk, Saudi Arabia.

Shaman AA, Mukhtar HB, Mirghani HO.

Electron Physician. 2017 Nov 25;9(11):5697-5704. doi: 10.19082/5697. eCollection 2017 Nov.


Risk Factors for Early Preterm Birth at King Salman Armed Force Hospital in 2010.

Alansi BA, Mukhtar HB, Alazizi MA, Zuiran AA, Al-Atawi AM, Al-Sabah BA, Al-Yami SS.

Open Access Maced J Med Sci. 2017 Nov 18;5(7):1016-1020. doi: 10.3889/oamjms.2017.103. eCollection 2017 Dec 15.


Evaluating the Potential of Oleaginous Yeasts as Feedstock for Biodiesel Production.

Mukhtar H, Suliman SM, Shabbir A, Mumtaz MW, Rashid U, Rahimuddin SA.

Protein Pept Lett. 2018;25(2):195-201. doi: 10.2174/0929866525666180122112805.


Targeting epigenome with dietary nutrients in cancer: Current advances and future challenges.

Khan MI, Rath S, Adhami VM, Mukhtar H.

Pharmacol Res. 2018 Mar;129:375-387. doi: 10.1016/j.phrs.2017.12.008. Epub 2017 Dec 9. Review.


Synthetic transcription elongation factors license transcription across repressive chromatin.

Erwin GS, Grieshop MP, Ali A, Qi J, Lawlor M, Kumar D, Ahmad I, McNally A, Teider N, Worringer K, Sivasankaran R, Syed DN, Eguchi A, Ashraf M, Jeffery J, Xu M, Park PMC, Mukhtar H, Srivastava AK, Faruq M, Bradner JE, Ansari AZ.

Science. 2017 Dec 22;358(6370):1617-1622. doi: 10.1126/science.aan6414. Epub 2017 Nov 30.


Ousting RAGE in melanoma: A viable therapeutic target?

Syed DN, Aljohani A, Waseem D, Mukhtar H.

Semin Cancer Biol. 2018 Apr;49:20-28. doi: 10.1016/j.semcancer.2017.10.008. Epub 2017 Oct 24. Review.


The Outcome of Assisted Reproductive Techniques among Couples with Male Factors at Prince Khalid Bin Sultan Fertility Centre, Kingdom of Saudi Arabia.

Mukhtar HB, Shaman A, Mirghani HO, Almasalmah AA.

Open Access Maced J Med Sci. 2017 Aug 6;5(5):603-607. doi: 10.3889/oamjms.2017.102. eCollection 2017 Aug 15.


Comparative Antileukemic Activity of a Tetranorditerpene Isolated from Polyalthia longifolia Leaves and the Derivative against Human Leukemia HL-60 Cells.

Afolabi S, Olorundare O, Ninomiya M, Babatunde A, Mukhtar H, Koketsu M.

J Oleo Sci. 2017 Oct 1;66(10):1169-1174. doi: 10.5650/jos.ess17042. Epub 2017 Sep 15.


Genetic Variation and Its Reflection on Posttranslational Modifications in Frequency Clock and Mating Type a-1 Proteins in Sordaria fimicola.

Arif R, Akram F, Jamil T, Mukhtar H, Lee SF, Saleem M.

Biomed Res Int. 2017;2017:1268623. doi: 10.1155/2017/1268623. Epub 2017 Jun 21.


Modeling Nitrogen Dynamics in a Waste Stabilization Pond System Using Flexible Modeling Environment with MCMC.

Mukhtar H, Lin YP, Shipin OV, Petway JR.

Int J Environ Res Public Health. 2017 Jul 12;14(7). pii: E765. doi: 10.3390/ijerph14070765.


Hypoxia driven glycation: Mechanisms and therapeutic opportunities.

Khan MI, Rath S, Adhami VM, Mukhtar H.

Semin Cancer Biol. 2018 Apr;49:75-82. doi: 10.1016/j.semcancer.2017.05.008. Epub 2017 May 22. Review.


Melittin, a major peptide component of bee venom, and its conjugates in cancer therapy.

Rady I, Siddiqui IA, Rady M, Mukhtar H.

Cancer Lett. 2017 Aug 28;402:16-31. doi: 10.1016/j.canlet.2017.05.010. Epub 2017 May 20. Review.


Significantly enhanced biomass production of a novel bio-therapeutic strain Lactobacillus plantarum (AS-14) by developing low cost media cultivation strategy.

Manzoor A, Qazi JI, Haq IU, Mukhtar H, Rasool A.

J Biol Eng. 2017 May 5;11:17. doi: 10.1186/s13036-017-0059-2. eCollection 2017.


A Phase II Randomized, Double-blind, Presurgical Trial of Polyphenon E in Bladder Cancer Patients to Evaluate Pharmacodynamics and Bladder Tissue Biomarkers.

Gee JR, Saltzstein DR, Kim K, Kolesar J, Huang W, Havighurst TC, Wollmer BW, Stublaski J, Downs T, Mukhtar H, House MG, Parnes HL, Bailey HH.

Cancer Prev Res (Phila). 2017 May;10(5):298-307. doi: 10.1158/1940-6207.CAPR-16-0167. Epub 2017 Mar 21.


Targeted nanoparticles encapsulating (-)-epigallocatechin-3-gallate for prostate cancer prevention and therapy.

Sanna V, Singh CK, Jashari R, Adhami VM, Chamcheu JC, Rady I, Sechi M, Mukhtar H, Siddiqui IA.

Sci Rep. 2017 Feb 1;7:41573. doi: 10.1038/srep41573.


Sestrin-3 modulation is essential for therapeutic efficacy of cucurbitacin B in lung cancer cells.

Khan N, Jajeh F, Khan MI, Mukhtar E, Shabana SM, Mukhtar H.

Carcinogenesis. 2017 Feb 1;38(2):184-195. doi: 10.1093/carcin/bgw124.


Fisetin Enhances Chemotherapeutic Effect of Cabazitaxel against Human Prostate Cancer Cells.

Mukhtar E, Adhami VM, Siddiqui IA, Verma AK, Mukhtar H.

Mol Cancer Ther. 2016 Dec;15(12):2863-2874. Epub 2016 Oct 7.


Improving the diagnostic stage of the suspected colorectal cancer pathway: A quality improvement project.

Haddow JB, Walshe M, Aggarwal D, Thapar A, Hardman J, Wilson J, Oshowo A, Bhan C, Mukhtar H.

Healthc (Amst). 2016 Sep;4(3):225-34. doi: 10.1016/j.hjdsi.2015.09.004. Epub 2015 Sep 28.


Nanoencapsulation of dietary flavonoid fisetin: Formulation and in vitro antioxidant and α-glucosidase inhibition activities.

Sechi M, Syed DN, Pala N, Mariani A, Marceddu S, Brunetti A, Mukhtar H, Sanna V.

Mater Sci Eng C Mater Biol Appl. 2016 Nov 1;68:594-602. doi: 10.1016/j.msec.2016.06.042. Epub 2016 Jun 14.


Targeting signal transduction pathways of cancer stem cells for therapeutic opportunities of metastasis.

Iqbal W, Alkarim S, AlHejin A, Mukhtar H, Saini KS.

Oncotarget. 2016 Nov 15;7(46):76337-76353. doi: 10.18632/oncotarget.10942. Review.


Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice.

Chamcheu JC, Adhami VM, Esnault S, Sechi M, Siddiqui IA, Satyshur KA, Syed DN, Dodwad SM, Chaves-Rodriquez MI, Longley BJ, Wood GS, Mukhtar H.

Antioxid Redox Signal. 2017 Jan 10;26(2):49-69. doi: 10.1089/ars.2016.6769. Epub 2016 Oct 4.


Dietary flavonoid fisetin increases abundance of high-molecular-mass hyaluronan conferring resistance to prostate oncogenesis.

Lall RK, Syed DN, Khan MI, Adhami VM, Gong Y, Lucey JA, Mukhtar H.

Carcinogenesis. 2016 Sep;37(9):918-928. doi: 10.1093/carcin/bgw071. Epub 2016 Jun 22.


Nutrition in the cause and prevention of cancer: An update.

Adhami VM, Mukhtar H.

Mol Nutr Food Res. 2016 Jun;60(6):1226-7. doi: 10.1002/mnfr.201670064. No abstract available.


Exploring the molecular targets of dietary flavonoid fisetin in cancer.

Syed DN, Adhami VM, Khan N, Khan MI, Mukhtar H.

Semin Cancer Biol. 2016 Oct;40-41:130-140. doi: 10.1016/j.semcancer.2016.04.003. Epub 2016 May 6. Review.

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