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Items: 1 to 50 of 351

1.

CCL2-Mediated Reversal of Impaired Skin Wound Healing in Diabetic Mice by Normalization of Neovascularization and Collagen Accumulation.

Ishida Y, Kuninaka Y, Nosaka M, Furuta M, Kimura A, Taruya A, Yamamoto H, Shimada E, Akiyama M, Mukaida N, Kondo T.

J Invest Dermatol. 2019 Jun 24. pii: S0022-202X(19)31786-5. doi: 10.1016/j.jid.2019.05.022. [Epub ahead of print]

PMID:
31247201
2.

Retinoblastoma Inactivation Induces a Protumoral Microenvironment via Enhanced CCL2 Secretion.

Li F, Kitajima S, Kohno S, Yoshida A, Tange S, Sasaki S, Okada N, Nishimoto Y, Muranaka H, Nagatani N, Suzuki M, Masuda S, Thai TC, Nishiuchi T, Tanaka T, Barbie DA, Mukaida N, Takahashi C.

Cancer Res. 2019 Aug 1;79(15):3903-3915. doi: 10.1158/0008-5472.CAN-18-3604. Epub 2019 Jun 12.

PMID:
31189648
3.

Lung Macrophages: Multifunctional Regulator Cells for Metastatic Cells.

Mukaida N, Nosaka T, Nakamoto Y, Baba T.

Int J Mol Sci. 2018 Dec 29;20(1). pii: E116. doi: 10.3390/ijms20010116. Review.

4.

Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.

Nishimura T, Nakata A, Chen X, Nishi K, Meguro-Horike M, Sasaki S, Kita K, Horike SI, Saitoh K, Kato K, Igarashi K, Murayama T, Kohno S, Takahashi C, Mukaida N, Yano S, Soga T, Tojo A, Gotoh N.

Oncogene. 2019 Apr;38(14):2464-2481. doi: 10.1038/s41388-018-0589-1. Epub 2018 Dec 7.

5.

Prevention of lipopolysaccharide-induced preterm labor by the lack of CX3CL1-CX3CR1 interaction in mice.

Mizoguchi M, Ishida Y, Nosaka M, Kimura A, Kuninaka Y, Yahata T, Nanjo S, Toujima S, Minami S, Ino K, Mukaida N, Kondo T.

PLoS One. 2018 Nov 6;13(11):e0207085. doi: 10.1371/journal.pone.0207085. eCollection 2018.

6.

Contribution of the TNF-α (Tumor Necrosis Factor-α)-TNF-Rp55 (Tumor Necrosis Factor Receptor p55) Axis in the Resolution of Venous Thrombus.

Nosaka M, Ishida Y, Kimura A, Kuninaka Y, Taruya A, Furuta M, Mukaida N, Kondo T.

Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2638-2650. doi: 10.1161/ATVBAHA.118.311194.

PMID:
30354252
7.

Resveratrol stimulation induces interleukin-8 gene transcription via NF-κB.

Thiel G, Ulrich M, Mukaida N, Rössler OG.

Pharmacol Res. 2018 Aug;134:238-245. doi: 10.1016/j.phrs.2018.07.003. Epub 2018 Jul 6.

PMID:
30018026
8.

Emergence of immunotherapy as a novel way to treat hepatocellular carcinoma.

Mukaida N, Nakamoto Y.

World J Gastroenterol. 2018 May 7;24(17):1839-1858. doi: 10.3748/wjg.v24.i17.1839. Review.

9.

Involvement of Prokineticin 2-expressing Neutrophil Infiltration in 5-Fluorouracil-induced Aggravation of Breast Cancer Metastasis to Lung.

Sasaki S, Baba T, Muranaka H, Tanabe Y, Takahashi C, Matsugo S, Mukaida N.

Mol Cancer Ther. 2018 Jul;17(7):1515-1525. doi: 10.1158/1535-7163.MCT-17-0845. Epub 2018 Apr 11.

10.

Protective Roles of Interferon-γ in Cardiac Hypertrophy Induced by Sustained Pressure Overload.

Kimura A, Ishida Y, Furuta M, Nosaka M, Kuninaka Y, Taruya A, Mukaida N, Kondo T.

J Am Heart Assoc. 2018 Mar 19;7(6). pii: e008145. doi: 10.1161/JAHA.117.008145.

11.

Erratum to 'Inhibition of human cytomegalovirus replication by tricin is associated with depressed CCL2 expression' [Antiviral Research (2017) 15-19].

Akai Y, Sadanari H, Takemoto M, Uchide N, Daikoku T, Mukaida N, Murayama T.

Antiviral Res. 2018 Mar;151:105. doi: 10.1016/j.antiviral.2018.02.008. No abstract available.

PMID:
29519616
12.

Alveolar Macrophages Drive Hepatocellular Carcinoma Lung Metastasis by Generating Leukotriene B4.

Nosaka T, Baba T, Tanabe Y, Sasaki S, Nishimura T, Imamura Y, Yurino H, Hashimoto S, Arita M, Nakamoto Y, Mukaida N.

J Immunol. 2018 Mar 1;200(5):1839-1852. doi: 10.4049/jimmunol.1700544. Epub 2018 Jan 29.

13.

Essential involvement of the CX3CL1-CX3CR1 axis in bleomycin-induced pulmonary fibrosis via regulation of fibrocyte and M2 macrophage migration.

Ishida Y, Kimura A, Nosaka M, Kuninaka Y, Hemmi H, Sasaki I, Kaisho T, Mukaida N, Kondo T.

Sci Rep. 2017 Dec 4;7(1):16833. doi: 10.1038/s41598-017-17007-8.

14.

Stimulation of transient receptor potential M3 (TRPM3) channels increases interleukin-8 gene promoter activity involving AP-1 and extracellular signal-regulated protein kinase.

Rubil S, Lesch A, Mukaida N, Thiel G.

Cytokine. 2018 Mar;103:133-141. doi: 10.1016/j.cyto.2017.09.020. Epub 2017 Oct 2.

PMID:
28982580
15.

Inhibition of human cytomegalovirus replication by tricin is associated with depressed CCL2 expression.

Akai Y, Sadanari H, Takemoto M, Uchide N, Daikoku T, Mukaida N, Murayama T.

Antiviral Res. 2017 Dec;148:15-19. doi: 10.1016/j.antiviral.2017.09.018. Epub 2017 Sep 28. Erratum in: Antiviral Res. 2018 Mar;151:105.

PMID:
28965916
16.

Chemokines as a Conductor of Bone Marrow Microenvironment in Chronic Myeloid Leukemia.

Mukaida N, Tanabe Y, Baba T.

Int J Mol Sci. 2017 Aug 22;18(8). pii: E1824. doi: 10.3390/ijms18081824. Review.

17.

DPP-4 Inhibition by Linagliptin Attenuates Obesity-Related Inflammation and Insulin Resistance by Regulating M1/M2 Macrophage Polarization.

Zhuge F, Ni Y, Nagashimada M, Nagata N, Xu L, Mukaida N, Kaneko S, Ota T.

Diabetes. 2016 Oct;65(10):2966-79. doi: 10.2337/db16-0317. Epub 2016 Jul 21.

18.
19.

Fibroblasts, an inconspicuous but essential player in colon cancer development and progression.

Mukaida N, Sasaki S.

World J Gastroenterol. 2016 Jun 21;22(23):5301-16. doi: 10.3748/wjg.v22.i23.5301. Review.

20.

Gemcitabine induces cell senescence in human pancreatic cancer cell lines.

Song Y, Baba T, Mukaida N.

Biochem Biophys Res Commun. 2016 Aug 26;477(3):515-9. doi: 10.1016/j.bbrc.2016.06.063. Epub 2016 Jun 14.

PMID:
27311854
21.

Essential roles of the interaction between cancer cell-derived chemokine, CCL4, and intra-bone CCR5-expressing fibroblasts in breast cancer bone metastasis.

Sasaki S, Baba T, Nishimura T, Hayakawa Y, Hashimoto S, Gotoh N, Mukaida N.

Cancer Lett. 2016 Aug 1;378(1):23-32. doi: 10.1016/j.canlet.2016.05.005. Epub 2016 May 10.

PMID:
27177471
22.

MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice.

Baba T, Tanabe Y, Yoshikawa S, Yamanishi Y, Morishita S, Komatsu N, Karasuyama H, Hirao A, Mukaida N.

Blood. 2016 May 26;127(21):2607-17. doi: 10.1182/blood-2015-10-673087. Epub 2016 Mar 22.

23.

[Chemokines in chronic myeloid leukemia].

Mukaida N, Baba T.

Rinsho Ketsueki. 2016 Feb;57(2):129-36. doi: 10.11406/rinketsu.57.129. Review. Japanese.

PMID:
26935630
24.

Design and synthesis of an in vivo-efficacious PIM3 kinase inhibitor as a candidate anti-pancreatic cancer agent.

Nakano H, Hasegawa T, Saito N, Furukawa K, Mukaida N, Kojima H, Okabe T, Nagano T.

Bioorg Med Chem Lett. 2015 Dec 15;25(24):5687-93. doi: 10.1016/j.bmcl.2015.10.098. Epub 2015 Oct 31.

PMID:
26547690
25.

High-dose cyclophosphamide induces specific tumor immunity with concomitant recruitment of LAMP1/CD107a-expressing CD4-positive T cells into tumor sites.

Naito T, Baba T, Takeda K, Sasaki S, Nakamoto Y, Mukaida N.

Cancer Lett. 2015 Sep 28;366(1):93-9. doi: 10.1016/j.canlet.2015.06.009. Epub 2015 Jun 24.

PMID:
26116901
26.

MicroRNA-33a-mediated downregulation of Pim-3 kinase expression renders human pancreatic cancer cells sensitivity to gemcitabine.

Liang C, Yu XJ, Guo XZ, Sun MH, Wang Z, Song Y, Ni QX, Li HY, Mukaida N, Li YY.

Oncotarget. 2015 Jun 10;6(16):14440-55.

27.

Suppressed rate of carcinogenesis and decreases in tumour volume and lung metastasis in CXCL14/BRAK transgenic mice.

Hata R, Izukuri K, Kato Y, Sasaki S, Mukaida N, Maehata Y, Miyamoto C, Akasaka T, Yang X, Nagashima Y, Takeda K, Kiyono T, Taniguchi M.

Sci Rep. 2015 Mar 13;5:9083. doi: 10.1038/srep09083.

28.

Gemcitabine-induced CXCL8 expression counteracts its actions by inducing tumor neovascularization.

Song Y, Baba T, Li YY, Furukawa K, Tanabe Y, Matsugo S, Sasaki S, Mukaida N.

Biochem Biophys Res Commun. 2015 Mar 6;458(2):341-6. doi: 10.1016/j.bbrc.2015.01.112. Epub 2015 Jan 31.

PMID:
25646691
29.

Lysophosphatidic acid receptor LPAR6 supports the tumorigenicity of hepatocellular carcinoma.

Mazzocca A, Dituri F, De Santis F, Filannino A, Lopane C, Betz RC, Li YY, Mukaida N, Winter P, Tortorella C, Giannelli G, Sabbà C.

Cancer Res. 2015 Feb 1;75(3):532-43. doi: 10.1158/0008-5472.CAN-14-1607. Epub 2015 Jan 14.

30.

Thymidine phosphorylase activates NFκB and stimulates the expression of angiogenic and metastatic factors in human cancer cells.

Tabata S, Ikeda R, Yamamoto M, Shimaoka S, Mukaida N, Takeda Y, Yamada K, Soga T, Furukawa T, Akiyama S.

Oncotarget. 2014 Nov 15;5(21):10473-85.

31.

Human cytomegalovirus replication supported by virus-induced activation of CCL2-CCR2 interactions.

Murayama T, Kikuchi M, Miita T, Yamada R, Matsubara K, Sadanari H, Mukaida N.

Biochem Biophys Res Commun. 2014 Oct 24;453(3):321-5. doi: 10.1016/j.bbrc.2014.09.071. Epub 2014 Sep 26.

PMID:
25261725
32.

Pathophysiological roles of Pim-3 kinase in pancreatic cancer development and progression.

Li YY, Mukaida N.

World J Gastroenterol. 2014 Jul 28;20(28):9392-404. doi: 10.3748/wjg.v20.i28.9392. Review.

33.

Chemokines in cancer development and progression and their potential as targeting molecules for cancer treatment.

Mukaida N, Sasaki S, Baba T.

Mediators Inflamm. 2014;2014:170381. doi: 10.1155/2014/170381. Epub 2014 May 22. Review.

34.

Efficient generation of highly immunocompetent dendritic cells from peripheral blood of patients with hepatitis C virus-related hepatocellular carcinoma.

Kitahara M, Mizukoshi E, Nakamoto Y, Mukaida N, Matsushima K, Kaneko S.

Int Immunopharmacol. 2014 Aug;21(2):346-53. doi: 10.1016/j.intimp.2014.05.023. Epub 2014 Jun 2.

PMID:
24893118
35.

Intestinal microbiota: unexpected alliance with tumor therapy.

Mukaida N.

Immunotherapy. 2014;6(3):231-3. doi: 10.2217/imt.13.170.

PMID:
24762069
36.

Splicing inhibition induces gene expression through canonical NF-κB pathway and extracellular signal-related kinase activation.

Khan K, Schneider-Poetsch T, Ishfaq M, Ito A, Yoshimoto R, Mukaida N, Yoshida M.

FEBS Lett. 2014 Mar 18;588(6):1053-7. doi: 10.1016/j.febslet.2014.02.018. Epub 2014 Feb 20.

37.

Crucial involvement of the CCL3-CCR5 axis-mediated fibroblast accumulation in colitis-associated carcinogenesis in mice.

Sasaki S, Baba T, Shinagawa K, Matsushima K, Mukaida N.

Int J Cancer. 2014 Sep 15;135(6):1297-306. doi: 10.1002/ijc.28779. Epub 2014 Feb 20.

38.

Role of macrophage inflammatory protein (MIP)-1α/CCL3 in leukemogenesis.

Baba T, Mukaida N.

Mol Cell Oncol. 2014 Jul 15;1(1):e29899. doi: 10.4161/mco.29899. eCollection 2014. Review.

39.

Ag and IL-2 immune complexes efficiently expand Ag-specific Treg cells that migrate in response to chemokines and reduce localized immune responses.

Hamano R, Baba T, Sasaki S, Tomaru U, Ishizu A, Kawano M, Yamagishi M, Mukaida N.

Eur J Immunol. 2014 Apr;44(4):1005-15. doi: 10.1002/eji.201343434. Epub 2014 Jan 13.

40.

MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia.

Baba T, Naka K, Morishita S, Komatsu N, Hirao A, Mukaida N.

J Exp Med. 2013 Nov 18;210(12):2661-73. doi: 10.1084/jem.20130112. Epub 2013 Oct 28.

41.

A novel regulatory mechanism of Pim-3 kinase stability and its involvement in pancreatic cancer progression.

Zhang F, Liu B, Wang Z, Yu XJ, Ni QX, Yang WT, Mukaida N, Li YY.

Mol Cancer Res. 2013 Dec;11(12):1508-20. doi: 10.1158/1541-7786.MCR-13-0389. Epub 2013 Oct 28.

42.

TNF-α/TNFR1 signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 in tumor cells.

Oshima H, Ishikawa T, Yoshida GJ, Naoi K, Maeda Y, Naka K, Ju X, Yamada Y, Minamoto T, Mukaida N, Saya H, Oshima M.

Oncogene. 2014 Jul 17;33(29):3820-9. doi: 10.1038/onc.2013.356. Epub 2013 Aug 26.

PMID:
23975421
43.

N-myc downstream-regulated gene 1 promotes tumor inflammatory angiogenesis through JNK activation and autocrine loop of interleukin-1α by human gastric cancer cells.

Murakami Y, Watari K, Shibata T, Uba M, Ureshino H, Kawahara A, Abe H, Izumi H, Mukaida N, Kuwano M, Ono M.

J Biol Chem. 2013 Aug 30;288(35):25025-37. doi: 10.1074/jbc.M113.472068. Epub 2013 Jul 11.

44.

CCL2/CCR2 augments the production of transforming growth factor-beta1, type 1 collagen and CCL2 by human CD45-/collagen 1-positive cells under high glucose concentrations.

Hara A, Sakai N, Furuichi K, Sakai Y, Takeya M, Bucala R, Mukaida N, Takuwa Y, Matsushima K, Kaneko S, Wada T.

Clin Exp Nephrol. 2013 Dec;17(6):793-804. doi: 10.1007/s10157-013-0796-6. Epub 2013 Apr 6.

PMID:
23564379
45.

Inflammatory monocytes recruited to allergic skin acquire an anti-inflammatory M2 phenotype via basophil-derived interleukin-4.

Egawa M, Mukai K, Yoshikawa S, Iki M, Mukaida N, Kawano Y, Minegishi Y, Karasuyama H.

Immunity. 2013 Mar 21;38(3):570-80. doi: 10.1016/j.immuni.2012.11.014. Epub 2013 Feb 21.

46.

Displays of paternal mouse pup retrieval following communicative interaction with maternal mates.

Liu HX, Lopatina O, Higashida C, Fujimoto H, Akther S, Inzhutova A, Liang M, Zhong J, Tsuji T, Yoshihara T, Sumi K, Ishiyama M, Ma WJ, Ozaki M, Yagitani S, Yokoyama S, Mukaida N, Sakurai T, Hori O, Yoshioka K, Hirao A, Kato Y, Ishihara K, Kato I, Okamoto H, Cherepanov SM, Salmina AB, Hirai H, Asano M, Brown DA, Nagano I, Higashida H.

Nat Commun. 2013;4:1346. doi: 10.1038/ncomms2336.

47.

Crucial involvement of tumor-associated neutrophils in the regulation of chronic colitis-associated carcinogenesis in mice.

Shang K, Bai YP, Wang C, Wang Z, Gu HY, Du X, Zhou XY, Zheng CL, Chi YY, Mukaida N, Li YY.

PLoS One. 2012;7(12):e51848. doi: 10.1371/journal.pone.0051848. Epub 2012 Dec 18.

48.

Chemokine receptors CCR2 and CX3CR1 regulate skin fibrosis in the mouse model of cytokine-induced systemic sclerosis.

Arai M, Ikawa Y, Chujo S, Hamaguchi Y, Ishida W, Shirasaki F, Hasegawa M, Mukaida N, Fujimoto M, Takehara K.

J Dermatol Sci. 2013 Mar;69(3):250-8. doi: 10.1016/j.jdermsci.2012.10.010. Epub 2012 Oct 24.

PMID:
23142052
49.

Novel process of intrathymic tumor-immune tolerance through CCR2-mediated recruitment of Sirpα+ dendritic cells: a murine model.

Baba T, Badr Mel S, Tomaru U, Ishizu A, Mukaida N.

PLoS One. 2012;7(7):e41154. doi: 10.1371/journal.pone.0041154. Epub 2012 Jul 16.

50.

Interferon-γ is protective in cisplatin-induced renal injury by enhancing autophagic flux.

Kimura A, Ishida Y, Inagaki M, Nakamura Y, Sanke T, Mukaida N, Kondo T.

Kidney Int. 2012 Nov;82(10):1093-104. doi: 10.1038/ki.2012.240. Epub 2012 Jul 11.

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