Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 9

1.

Discovery of WAY-260022, a Potent and Selective Inhibitor of the Norepinephrine Transporter.

Gavrin LK, Mahaney PE, Jenkins D, Nogle LM, Mugford CA, Huselton C, Leiter J, Johnston GH, Bray JA, Burroughs KD, Cosmi SA, Alfinito P, Ho DM, Deecher DC, Trybulski EJ.

ACS Med Chem Lett. 2010 Mar 25;1(3):91-5. doi: 10.1021/ml100009p. eCollection 2010 Jun 10.

2.

1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: potent, selective, and orally efficacious norepinephrine reuptake inhibitors.

Zhang P, Terefenko EA, Bray J, Deecher D, Fensome A, Harrison J, Kim C, Koury E, Mark L, McComas CC, Mugford CA, Trybulski EJ, Vu AT, Whiteside GT, Mahaney PE.

J Med Chem. 2009 Sep 24;52(18):5703-11. doi: 10.1021/jm900888c.

PMID:
19722525
3.

Structure-activity relationships of the cycloalkanol ethylamine scaffold: discovery of selective norepinephrine reuptake inhibitors.

Mahaney PE, Gavrin LK, Trybulski EJ, Stack GP, Vu TA, Cohn ST, Ye F, Belardi JK, Santilli AA, Sabatucci JP, Leiter J, Johnston GH, Bray JA, Burroughs KD, Cosmi SA, Leventhal L, Koury EJ, Zhang Y, Mugford CA, Ho DM, Rosenzweig-Lipson SJ, Platt B, Smith VA, Deecher DC.

J Med Chem. 2008 Jul 10;51(13):4038-49. doi: 10.1021/jm8002262. Epub 2008 Jun 17.

PMID:
18557608
4.

Design, synthesis, and SAR of new pyrrole-oxindole progesterone receptor modulators leading to 5-(7-fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348).

Fensome A, Adams WR, Adams AL, Berrodin TJ, Cohen J, Huselton C, Illenberger A, Kern JC, Hudak VA, Marella MA, Melenski EG, McComas CC, Mugford CA, Slayden OD, Yudt M, Zhang Z, Zhang P, Zhu Y, Winneker RC, Wrobel JE.

J Med Chem. 2008 Mar 27;51(6):1861-73. doi: 10.1021/jm701080t. Epub 2008 Mar 5.

PMID:
18318463
5.

Sex-dependent metabolism of xenobiotics.

Mugford CA, Kedderis GL.

Drug Metab Rev. 1998 Aug;30(3):441-98. Review.

PMID:
9710703
6.
7.

Furan-mediated uncoupling of hepatic oxidative phosphorylation in Fischer-344 rats: an early event in cell death.

Mugford CA, Carfagna MA, Kedderis GL.

Toxicol Appl Pharmacol. 1997 May;144(1):1-11.

PMID:
9169064
9.

1-Aminobenzotriazole-induced destruction of hepatic and renal cytochromes P450 in male Sprague-Dawley rats.

Mugford CA, Mortillo M, Mico BA, Tarloff JB.

Fundam Appl Toxicol. 1992 Jul;19(1):43-9.

PMID:
1397800

Supplemental Content

Loading ...
Support Center