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Items: 10

1.

Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation.

Park DS, Akuffo AA, Muench DE, Grimes HL, Epling-Burnette PK, Maini PK, Anderson ARA, Bonsall MB.

PLoS Comput Biol. 2019 Apr 26;15(4):e1006913. doi: 10.1371/journal.pcbi.1006913. eCollection 2019 Apr.

2.

Phospho serine and threonine analysis of normal and mutated granulocyte colony stimulating factor receptors.

Dwivedi P, Muench DE, Wagner M, Azam M, Grimes HL, Greis KD.

Sci Data. 2019 Apr 9;6(1):21. doi: 10.1038/s41597-019-0015-8.

3.

SKI controls MDS-associated chronic TGF-β signaling, aberrant splicing, and stem cell fitness.

Muench DE, Ferchen K, Velu CS, Pradhan K, Chetal K, Chen X, Weirauch MT, Colmenares C, Verma A, Salomonis N, Grimes HL.

Blood. 2018 Nov 22;132(21):e24-e34. doi: 10.1182/blood-2018-06-860890. Epub 2018 Sep 24.

4.

miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential.

Meyer SE, Muench DE, Rogers AM, Newkold TJ, Orr E, O'Brien E, Perentesis JP, Doench JG, Lal A, Morris PJ, Thomas CJ, Lieberman J, McGlinn E, Aronow BJ, Salomonis N, Grimes HL.

J Exp Med. 2018 Aug 6;215(8):2115-2136. doi: 10.1084/jem.20171312. Epub 2018 Jul 11.

5.

Time resolved quantitative phospho-tyrosine analysis reveals Bruton's Tyrosine kinase mediated signaling downstream of the mutated granulocyte-colony stimulating factor receptors.

Dwivedi P, Muench DE, Wagner M, Azam M, Grimes HL, Greis KD.

Leukemia. 2019 Jan;33(1):75-87. doi: 10.1038/s41375-018-0188-8. Epub 2018 Jul 5.

6.

Obesity alters the long-term fitness of the hematopoietic stem cell compartment through modulation of Gfi1 expression.

Lee JM, Govindarajah V, Goddard B, Hinge A, Muench DE, Filippi MD, Aronow B, Cancelas JA, Salomonis N, Grimes HL, Reynaud D.

J Exp Med. 2018 Feb 5;215(2):627-644. doi: 10.1084/jem.20170690. Epub 2017 Dec 27.

7.

Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes.

Yáñez A, Coetzee SG, Olsson A, Muench DE, Berman BP, Hazelett DJ, Salomonis N, Grimes HL, Goodridge HS.

Immunity. 2017 Nov 21;47(5):890-902.e4. doi: 10.1016/j.immuni.2017.10.021.

8.

The miR-23a~27a~24-2 microRNA cluster buffers transcription and signaling pathways during hematopoiesis.

Kurkewich JL, Hansen J, Klopfenstein N, Zhang H, Wood C, Boucher A, Hickman J, Muench DE, Grimes HL, Dahl R.

PLoS Genet. 2017 Jul 13;13(7):e1006887. doi: 10.1371/journal.pgen.1006887. eCollection 2017 Jul.

9.

DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.

Meyer SE, Qin T, Muench DE, Masuda K, Venkatasubramanian M, Orr E, Suarez L, Gore SD, Delwel R, Paietta E, Tallman MS, Fernandez H, Melnick A, Le Beau MM, Kogan S, Salomonis N, Figueroa ME, Grimes HL.

Cancer Discov. 2016 May;6(5):501-15. doi: 10.1158/2159-8290.CD-16-0008. Epub 2016 Mar 25.

10.

Transcriptional Control of Stem and Progenitor Potential.

Muench DE, Grimes HL.

Curr Stem Cell Rep. 2015 Sep;1(3):139-150. Epub 2015 Jun 26.

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