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Items: 1 to 50 of 92

1.

Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis.

Lloyd KA, Wigerblad G, Sahlström P, Garimella MG, Chemin K, Steen J, Titcombe PJ, Marklein B, Zhou D, Stålesen R, Ossipova E, Lundqvist C, Ekwall O, Rönnelid J, Mueller DL, Karlsson MCI, Kaplan MJ, Skriner K, Klareskog L, Wermeling F, Malmström V, Grönwall C.

Front Immunol. 2019 Jan 4;9:3033. doi: 10.3389/fimmu.2018.03033. eCollection 2018.

2.

Alum adjuvant is more effective than MF59 at prompting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of a vaccine against opioid use disorders.

Robinson C, Baehr C, Schmiel SE, Accetturo C, Mueller DL, Pravetoni M.

Hum Vaccin Immunother. 2019;15(4):909-917. doi: 10.1080/21645515.2018.1558697. Epub 2019 Feb 20.

PMID:
30625019
3.

Adenosine 2a Receptor Signal Blockade of Murine Autoimmune Arthritis via Inhibition of Pathogenic Germinal Center-Follicular Helper T Cells.

Schmiel SE, Kalekar LA, Zhang N, Blankespoor TW, Robinson LJ, Mueller DL.

Arthritis Rheumatol. 2019 May;71(5):773-783. doi: 10.1002/art.40796. Epub 2019 Mar 25.

PMID:
30516351
4.

Recognition of Amino Acid Motifs, Rather Than Specific Proteins, by Human Plasma Cell-Derived Monoclonal Antibodies to Posttranslationally Modified Proteins in Rheumatoid Arthritis.

Steen J, Forsström B, Sahlström P, Odowd V, Israelsson L, Krishnamurthy A, Badreh S, Mathsson Alm L, Compson J, Ramsköld D, Ndlovu W, Rapecki S, Hansson M, Titcombe PJ, Bang H, Mueller DL, Catrina AI, Grönwall C, Skriner K, Nilsson P, Lightwood D, Klareskog L, Malmström V.

Arthritis Rheumatol. 2019 Feb;71(2):196-209. doi: 10.1002/art.40699.

5.

Pathogenic Citrulline-Multispecific B Cell Receptor Clades in Rheumatoid Arthritis.

Titcombe PJ, Wigerblad G, Sippl N, Zhang N, Shmagel AK, Sahlström P, Zhang Y, Barsness LO, Ghodke-Puranik Y, Baharpoor A, Hansson M, Israelsson L, Skriner K, Niewold TB, Klareskog L, Svensson CI, Amara K, Malmström V, Mueller DL.

Arthritis Rheumatol. 2018 Dec;70(12):1933-1945. doi: 10.1002/art.40590. Epub 2018 Oct 18.

6.

Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: Implications for B-cell selection.

Lloyd KA, Steen J, Amara K, Titcombe PJ, Israelsson L, Lundström SL, Zhou D, Zubarev RA, Reed E, Piccoli L, Gabay C, Lanzavecchia A, Baeten D, Lundberg K, Mueller DL, Klareskog L, Malmström V, Grönwall C.

Eur J Immunol. 2018 Jun;48(6):1030-1045. doi: 10.1002/eji.201747446. Epub 2018 Apr 6.

7.

Role of bone marrow-derived CD11c+ dendritic cells in systolic overload-induced left ventricular inflammation, fibrosis and hypertrophy.

Wang H, Kwak D, Fassett J, Liu X, Yao W, Weng X, Xu X, Xu Y, Bache RJ, Mueller DL, Chen Y.

Basic Res Cardiol. 2017 May;112(3):25. doi: 10.1007/s00395-017-0615-4. Epub 2017 Mar 27.

8.

Relationship between CD4 Regulatory T Cells and Anergy In Vivo.

Kalekar LA, Mueller DL.

J Immunol. 2017 Apr 1;198(7):2527-2533. doi: 10.4049/jimmunol.1602031. Review.

9.

Cutting Edge: Adenosine A2a Receptor Signals Inhibit Germinal Center T Follicular Helper Cell Differentiation during the Primary Response to Vaccination.

Schmiel SE, Yang JA, Jenkins MK, Mueller DL.

J Immunol. 2017 Jan 15;198(2):623-628. doi: 10.4049/jimmunol.1601686. Epub 2016 Dec 16.

10.

CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors.

Kalekar LA, Schmiel SE, Nandiwada SL, Lam WY, Barsness LO, Zhang N, Stritesky GL, Malhotra D, Pauken KE, Linehan JL, O'Sullivan MG, Fife BT, Hogquist KA, Jenkins MK, Mueller DL.

Nat Immunol. 2016 Mar;17(3):304-14. doi: 10.1038/ni.3331. Epub 2016 Feb 1.

11.

The frequency of naive and early-activated hapten-specific B cell subsets dictates the efficacy of a therapeutic vaccine against prescription opioid abuse.

Laudenbach M, Baruffaldi F, Vervacke JS, Distefano MD, Titcombe PJ, Mueller DL, Tubo NJ, Griffith TS, Pravetoni M.

J Immunol. 2015 Jun 15;194(12):5926-36. doi: 10.4049/jimmunol.1500385. Epub 2015 May 13.

12.

Absence of clinical findings reliably excludes unstable cervical spine injuries in children 5 years or younger.

Hale DF, Fitzpatrick CM, Doski JJ, Stewart RM, Mueller DL.

J Trauma Acute Care Surg. 2015 May;78(5):943-8. doi: 10.1097/TA.0000000000000603.

PMID:
25909413
13.

Natural history and clinical implications of nondepressed skull fracture in young children.

Hassan SF, Cohn SM, Admire J, Nunez-Cantu O, Arar Y, Myers JG, Dent DL, Eastridge BJ, Cestero RF, Gunst M, Markowski H, Keric N, Liao L, Mueller DL.

J Trauma Acute Care Surg. 2014 Jul;77(1):166-9. doi: 10.1097/TA.0000000000000256.

PMID:
24977773
14.

Cutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice.

Pauken KE, Linehan JL, Spanier JA, Sahli NL, Kalekar LA, Binstadt BA, Moon JJ, Mueller DL, Jenkins MK, Fife BT.

J Immunol. 2013 Nov 15;191(10):4913-7. doi: 10.4049/jimmunol.1301927. Epub 2013 Oct 11.

15.

Macrophage scavenger receptor 1 (Msr1, SR-A) influences B cell autoimmunity by regulating soluble autoantigen concentration.

Haasken S, Auger JL, Taylor JJ, Hobday PM, Goudy BD, Titcombe PJ, Mueller DL, Binstadt BA.

J Immunol. 2013 Aug 1;191(3):1055-62. doi: 10.4049/jimmunol.1201680. Epub 2013 Jun 21.

16.

Murine thymic selection quantified using a unique method to capture deleted T cells.

Stritesky GL, Xing Y, Erickson JR, Kalekar LA, Wang X, Mueller DL, Jameson SC, Hogquist KA.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4679-84. doi: 10.1073/pnas.1217532110. Epub 2013 Mar 4.

17.

Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen.

Taylor JJ, Martinez RJ, Titcombe PJ, Barsness LO, Thomas SR, Zhang N, Katzman SD, Jenkins MK, Mueller DL.

J Exp Med. 2012 Oct 22;209(11):2065-77. doi: 10.1084/jem.20112272. Epub 2012 Oct 15.

18.

Estimating thyroid dose in pediatric CT exams from surface dose measurement.

Al-Senan R, Mueller DL, Hatab MR.

Phys Med Biol. 2012 Jul 7;57(13):4211-21. doi: 10.1088/0031-9155/57/13/4211. Epub 2012 Jun 8.

PMID:
22684053
19.

Arthritogenic self-reactive CD4+ T cells acquire an FR4hiCD73hi anergic state in the presence of Foxp3+ regulatory T cells.

Martinez RJ, Zhang N, Thomas SR, Nandiwada SL, Jenkins MK, Binstadt BA, Mueller DL.

J Immunol. 2012 Jan 1;188(1):170-81. doi: 10.4049/jimmunol.1101311. Epub 2011 Nov 28.

20.

Pregnancy and rheumatoid arthritis: insights into the immunology of fetal tolerance and control of autoimmunity.

Amin S, Peterson EJ, Reed AM, Mueller DL.

Curr Rheumatol Rep. 2011 Oct;13(5):449-55. doi: 10.1007/s11926-011-0199-1. Review.

PMID:
21750959
21.

Pediatric radiation exposure during the initial evaluation for blunt trauma.

Mueller DL, Hatab M, Al-Senan R, Cohn SM, Corneille MG, Dent DL, Michalek JE, Myers JG, Wolf SE, Stewart RM.

J Trauma. 2011 Mar;70(3):724-31. doi: 10.1097/TA.0b013e3182092ff8.

PMID:
21610365
22.

Mechanisms maintaining peripheral tolerance.

Mueller DL.

Nat Immunol. 2010 Jan;11(1):21-7. doi: 10.1038/ni.1817. Epub 2009 Dec 17. Review.

PMID:
20016506
23.

Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory.

Agarwal P, Raghavan A, Nandiwada SL, Curtsinger JM, Bohjanen PR, Mueller DL, Mescher MF.

J Immunol. 2009 Aug 1;183(3):1695-704. doi: 10.4049/jimmunol.0900592. Epub 2009 Jul 10.

25.

Langerhans cells are not required for efficient skin graft rejection.

Obhrai JS, Oberbarnscheidt M, Zhang N, Mueller DL, Shlomchik WD, Lakkis FG, Shlomchik MJ, Kaplan DH.

J Invest Dermatol. 2008 Aug;128(8):1950-5. doi: 10.1038/jid.2008.52. Epub 2008 Mar 13.

26.

Proliferating CD4+ T cells undergo immediate growth arrest upon cessation of TCR signaling in vivo.

Yarke CA, Dalheimer SL, Zhang N, Catron DM, Jenkins MK, Mueller DL.

J Immunol. 2008 Jan 1;180(1):156-62.

27.

Allopeptide-specific CD4(+) T cells facilitate the differentiation of directly alloreactive graft-infiltrating CD8(+) T Cells.

Richards DM, Zhang N, Dalheimer SL, Mueller DL.

Am J Transplant. 2007 Oct;7(10):2269-78.

28.

mTOR at the crossroads of T cell proliferation and tolerance.

Mondino A, Mueller DL.

Semin Immunol. 2007 Jun;19(3):162-72. Epub 2007 Mar 23. Review.

29.

Linking diacylglycerol kinase to T cell anergy.

Mueller DL.

Nat Immunol. 2006 Nov;7(11):1132-4. No abstract available.

PMID:
17053795
30.
31.
32.

CD25+Foxp3+ regulatory T cells facilitate CD4+ T cell clonal anergy induction during the recovery from lymphopenia.

Vanasek TL, Nandiwada SL, Jenkins MK, Mueller DL.

J Immunol. 2006 May 15;176(10):5880-9.

33.
34.

E3 ubiquitin ligases and their control of T cell autoreactivity.

Bonnevier JL, Zhang R, Mueller DL.

Arthritis Res Ther. 2005;7(6):233-42. Epub 2005 Oct 12. Review.

35.

Gene expression profiling in murine obliterative airway disease.

Lande JD, Dalheimer SL, Mueller DL, Hertz MI, King RA.

Am J Transplant. 2005 Sep;5(9):2170-84.

36.
37.

Visualizing the first 50 hr of the primary immune response to a soluble antigen.

Catron DM, Itano AA, Pape KA, Mueller DL, Jenkins MK.

Immunity. 2004 Sep;21(3):341-7. Review.

38.

E3 ubiquitin ligases as T cell anergy factors.

Mueller DL.

Nat Immunol. 2004 Sep;5(9):883-90. Review.

PMID:
15334084
40.

Trachea allograft class I molecules directly activate and retain CD8+ T cells that cause obliterative airways disease.

Richards DM, Dalheimer SL, Hertz MI, Mueller DL.

J Immunol. 2003 Dec 15;171(12):6919-28.

41.

The effect of the bovine hemoglobin oxygen therapeutic HBOC-201 on human neutrophil activation in vitro.

Ortegon DP, Dixon PS, Crow KK, Mueller DL, Kerby JD.

J Trauma. 2003 Oct;55(4):755-60; discussion 760-1.

PMID:
14566134
42.

A comparison of the hemoglobin-based oxygen carrier HBOC-201 to other low-volume resuscitation fluids in a model of controlled hemorrhagic shock.

Sampson JB, Davis MR, Mueller DL, Kashyap VS, Jenkins DH, Kerby JD.

J Trauma. 2003 Oct;55(4):747-54.

PMID:
14566133
43.

Tuning the immune system: competing positive and negative feedback loops.

Mueller DL.

Nat Immunol. 2003 Mar;4(3):210-1. No abstract available.

PMID:
12605227
44.

The polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) is not toxic to neural cells in culture.

Ortegon DP, Davis MR, Dixon PS, Smith DL, Josephs JD, Mueller DL, Jenkins DH, Kerby JD.

J Trauma. 2002 Dec;53(6):1068-72.

PMID:
12478030
45.
46.

Constitutive active p21ras enhances primary T cell responsiveness to Ca2+ signals without interfering with the induction of clonal anergy.

Crespi D, Massa S, Basso V, Colombetti S, Mueller DL, Mondino A.

Eur J Immunol. 2002 Sep;32(9):2500-9.

48.

Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivo.

Zell T, Khoruts A, Ingulli E, Bonnevier JL, Mueller DL, Jenkins MK.

Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10805-10. Epub 2001 Sep 4.

49.

CD28 signaling augments Elk-1-dependent transcription at the c-fos gene during antigen stimulation.

Li W, Whaley CD, Bonnevier JL, Mondino A, Martin ME, Aagaard-Tillery KM, Mueller DL.

J Immunol. 2001 Jul 15;167(2):827-35.

50.

In vivo activation of antigen-specific CD4 T cells.

Jenkins MK, Khoruts A, Ingulli E, Mueller DL, McSorley SJ, Reinhardt RL, Itano A, Pape KA.

Annu Rev Immunol. 2001;19:23-45. Review.

PMID:
11244029

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