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Items: 1 to 50 of 74

1.

Metabolic Changes with Base-Loading in CKD.

Scialla JJ, Brown L, Gurley S, Corcoran DL, Bain JR, Muehlbauer MJ, O'Neal SK, M O'Connell T, Wolf M, Melamed ML, Hostetter TH, Abramowitz MK.

Clin J Am Soc Nephrol. 2018 Jun 22. pii: CJN.01830218. doi: 10.2215/CJN.01830218. [Epub ahead of print] No abstract available.

PMID:
29934431
2.

Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study.

Bartlett DB, Willis LH, Slentz CA, Hoselton A, Kelly L, Huebner JL, Kraus VB, Moss J, Muehlbauer MJ, Spielmann G, Kraus WE, Lord JM, Huffman KM.

Arthritis Res Ther. 2018 Jun 14;20(1):127. doi: 10.1186/s13075-018-1624-x.

3.

Dietary Patterns among Asian Indians Living in the United States Have Distinct Metabolomic Profiles That Are Associated with Cardiometabolic Risk.

Bhupathiraju SN, Guasch-Ferré M, Gadgil MD, Newgard CB, Bain JR, Muehlbauer MJ, Ilkayeva OR, Scholtens DM, Hu FB, Kanaya AM, Kandula NR.

J Nutr. 2018 Jul 1;148(7):1150-1159. doi: 10.1093/jn/nxy074.

4.

A Testosterone Metabolite 19-Hydroxyandrostenedione Induces Neuroendocrine Trans-Differentiation of Prostate Cancer Cells via an Ectopic Olfactory Receptor.

Abaffy T, Bain JR, Muehlbauer MJ, Spasojevic I, Lodha S, Bruguera E, O'Neal SK, Kim SY, Matsunami H.

Front Oncol. 2018 May 28;8:162. doi: 10.3389/fonc.2018.00162. eCollection 2018.

5.

Improvement in insulin resistance after gastric bypass surgery is correlated with a decline in plasma 2-hydroxybutyric acid.

Shantavasinkul PC, Muehlbauer MJ, Bain JR, Ilkayeva OR, Craig DM, Newgard CB, Svetkey LP, Shah SH, Torquati A.

Surg Obes Relat Dis. 2018 Apr 17. pii: S1550-7289(18)30173-4. doi: 10.1016/j.soard.2018.03.033. [Epub ahead of print]

PMID:
29805089
6.

Physiological mechanisms of sustained fumagillin-induced weight loss.

An J, Wang L, Patnode ML, Ridaura VK, Haldeman JM, Stevens RD, Ilkayeva O, Bain JR, Muehlbauer MJ, Glynn EL, Thomas S, Muoio D, Summers SA, Vath JE, Hughes TE, Gordon JI, Newgard CB.

JCI Insight. 2018 Mar 8;3(5). pii: 99453. doi: 10.1172/jci.insight.99453. [Epub ahead of print]

7.

Effect of Progressive Weight Loss on Lactate Metabolism: A Randomized Controlled Trial.

Chondronikola M, Magkos F, Yoshino J, Okunade AL, Patterson BW, Muehlbauer MJ, Newgard CB, Klein S.

Obesity (Silver Spring). 2018 Apr;26(4):683-688. doi: 10.1002/oby.22129. Epub 2018 Feb 24.

PMID:
29476613
8.

Erratum. Maternal BMI and Glycemia Impact the Fetal Metabolome. Diabetes Care 2017;40:902-910.

Lowe WL Jr, Bain JR, Nodzenski M, Reisetter AC, Muehlbauer MJ, Stevens RD, Ilkayeva OR, Lowe LP, Metzger BE, Newgard CB, Scholtens DM; HAPO Study Cooperative Research Group.

Diabetes Care. 2018 Mar;41(3):640. doi: 10.2337/dc18-er03b. Epub 2018 Jan 8. No abstract available.

9.

Effects of the kinase inhibitor sorafenib on heart, muscle, liver and plasma metabolism in vivo using non-targeted metabolomics analysis.

Jensen BC, Parry TL, Huang W, Beak JY, Ilaiwy A, Bain JR, Newgard CB, Muehlbauer MJ, Patterson C, Johnson GL, Willis MS.

Br J Pharmacol. 2017 Dec;174(24):4797-4811. doi: 10.1111/bph.14062. Epub 2017 Nov 24.

PMID:
28977680
10.

Recommendations for Improving Identification and Quantification in Non-Targeted, GC-MS-Based Metabolomic Profiling of Human Plasma.

Wang H, Muehlbauer MJ, O'Neal SK, Newgard CB, Hauser ER, Bain JR, Shah SH.

Metabolites. 2017 Aug 25;7(3). pii: E45. doi: 10.3390/metabo7030045.

11.

Exercise-Induced Alterations in Skeletal Muscle, Heart, Liver, and Serum Metabolome Identified by Non-Targeted Metabolomics Analysis.

Starnes JW, Parry TL, O'Neal SK, Bain JR, Muehlbauer MJ, Honcoop A, Ilaiwy A, Christopher PM, Patterson C, Willis MS.

Metabolites. 2017 Aug 8;7(3). pii: E40. doi: 10.3390/metabo7030040.

12.

Non-Targeted Metabolomics Analysis of Golden Retriever Muscular Dystrophy-Affected Muscles Reveals Alterations in Arginine and Proline Metabolism, and Elevations in Glutamic and Oleic Acid In Vivo.

Abdullah M, Kornegay JN, Honcoop A, Parry TL, Balog-Alvarez CJ, O'Neal SK, Bain JR, Muehlbauer MJ, Newgard CB, Patterson C, Willis MS.

Metabolites. 2017 Jul 29;7(3). pii: E38. doi: 10.3390/metabo7030038.

13.

Nicotinamide mononucleotide requires SIRT3 to improve cardiac function and bioenergetics in a Friedreich's ataxia cardiomyopathy model.

Martin AS, Abraham DM, Hershberger KA, Bhatt DP, Mao L, Cui H, Liu J, Liu X, Muehlbauer MJ, Grimsrud PA, Locasale JW, Payne RM, Hirschey MD.

JCI Insight. 2017 Jul 20;2(14). pii: 93885. doi: 10.1172/jci.insight.93885. [Epub ahead of print]

14.

Non-Targeted Metabolomics Analysis of the Effects of Tyrosine Kinase Inhibitors Sunitinib and Erlotinib on Heart, Muscle, Liver and Serum Metabolism In Vivo.

Jensen BC, Parry TL, Huang W, Ilaiwy A, Bain JR, Muehlbauer MJ, O'Neal SK, Patterson C, Johnson GL, Willis MS.

Metabolites. 2017 Jun 22;7(3). pii: E31. doi: 10.3390/metabo7030031.

15.

Targeted Metabolomics Demonstrates Distinct and Overlapping Maternal Metabolites Associated With BMI, Glucose, and Insulin Sensitivity During Pregnancy Across Four Ancestry Groups.

Jacob S, Nodzenski M, Reisetter AC, Bain JR, Muehlbauer MJ, Stevens RD, Ilkayeva OR, Lowe LP, Metzger BE, Newgard CB, Scholtens DM, Lowe WL Jr; HAPO Study Cooperative Research Group.

Diabetes Care. 2017 Jul;40(7):911-919. doi: 10.2337/dc16-2453.

16.

Maternal BMI and Glycemia Impact the Fetal Metabolome.

Lowe WL Jr, Bain JR, Nodzenski M, Reisetter AC, Muehlbauer MJ, Stevens RD, Ilkayeva OR, Lowe LP, Metzger BE, Newgard CB, Scholtens DM; HAPO Study Cooperative Research Group.

Diabetes Care. 2017 Jul;40(7):902-910. doi: 10.2337/dc16-2452. Erratum in: Diabetes Care. 2018 Jan 8;:.

17.

Sildenafil Treatment in Heart Failure With Preserved Ejection Fraction: Targeted Metabolomic Profiling in the RELAX Trial.

Wang H, Anstrom K, Ilkayeva O, Muehlbauer MJ, Bain JR, McNulty S, Newgard CB, Kraus WE, Hernandez A, Felker GM, Redfield M, Shah SH.

JAMA Cardiol. 2017 Aug 1;2(8):896-901. doi: 10.1001/jamacardio.2017.1239.

18.

Erratum to 'Cessation of biomechanical stretch model of C2C12 cells modelsmyocyte atrophy and anaplerotic changes in metabolism usingnon-targeted metabolomics analysisAmro' [Int. J. Biochem. Cell Biol. (2016) 80-92].

Ilaiwy A, Quintana MT, Bain JR, Muehlbauer MJ, Brown DI, Stansfield WE, Willis MS.

Int J Biochem Cell Biol. 2017 Jul;88:238-240. doi: 10.1016/j.biocel.2017.02.010. Epub 2017 Mar 19. No abstract available.

PMID:
28330772
19.

Lung injury-induced skeletal muscle wasting in aged mice is linked to alterations in long chain fatty acid metabolism.

Files DC, Ilaiwy A, Parry TL, Gibbs KW, Liu C, Bain JR, Delbono O, Muehlbauer MJ, Willis MS.

Metabolomics. 2016 Aug;12(8). pii: 134. doi: 10.1007/s11306-016-1079-5. Epub 2016 Jul 26.

20.

Mixture model normalization for non-targeted gas chromatography/mass spectrometry metabolomics data.

Reisetter AC, Muehlbauer MJ, Bain JR, Nodzenski M, Stevens RD, Ilkayeva O, Metzger BE, Newgard CB, Lowe WL Jr, Scholtens DM.

BMC Bioinformatics. 2017 Feb 2;18(1):84. doi: 10.1186/s12859-017-1501-7.

21.

Associations of maternal BMI and insulin resistance with the maternal metabolome and newborn outcomes.

Sandler V, Reisetter AC, Bain JR, Muehlbauer MJ, Nodzenski M, Stevens RD, Ilkayeva O, Lowe LP, Metzger BE, Newgard CB, Scholtens DM, Lowe WL Jr; HAPO Study Cooperative Research Group.

Diabetologia. 2017 Mar;60(3):518-530. doi: 10.1007/s00125-016-4182-2. Epub 2016 Dec 16.

22.

Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model.

Masko EM, Alfaqih MA, Solomon KR, Barry WT, Newgard CB, Muehlbauer MJ, Valilis NA, Phillips TE, Poulton SH, Freedland AR, Sun S, Dambal SK, Sanders SE, Macias E, Freeman MR, Dewhirst MW, Pizzo SV, Freedland SJ.

Prostate. 2017 Apr;77(5):446-457. doi: 10.1002/pros.23282. Epub 2016 Nov 30.

23.

Cessation of biomechanical stretch model of C2C12 cells models myocyte atrophy and anaplerotic changes in metabolism using non-targeted metabolomics analysis.

Ilaiwy A, Quintana MT, Bain JR, Muehlbauer MJ, Brown DI, Stansfield WE, Willis MS.

Int J Biochem Cell Biol. 2016 Oct;79:80-92. doi: 10.1016/j.biocel.2016.08.012. Epub 2016 Aug 8. Erratum in: Int J Biochem Cell Biol. 2017 Jul;88:238-240.

24.

Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure.

Hunter WG, Kelly JP, McGarrah RW 3rd, Khouri MG, Craig D, Haynes C, Ilkayeva O, Stevens RD, Bain JR, Muehlbauer MJ, Newgard CB, Felker GM, Hernandez AF, Velazquez EJ, Kraus WE, Shah SH.

J Am Heart Assoc. 2016 Jul 29;5(8). pii: e003190. doi: 10.1161/JAHA.115.003190.

25.

Effects of exercise training alone vs a combined exercise and nutritional lifestyle intervention on glucose homeostasis in prediabetic individuals: a randomised controlled trial.

Slentz CA, Bateman LA, Willis LH, Granville EO, Piner LW, Samsa GP, Setji TL, Muehlbauer MJ, Huffman KM, Bales CW, Kraus WE.

Diabetologia. 2016 Oct;59(10):2088-98. doi: 10.1007/s00125-016-4051-z. Epub 2016 Jul 15.

26.

Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export.

White PJ, Lapworth AL, An J, Wang L, McGarrah RW, Stevens RD, Ilkayeva O, George T, Muehlbauer MJ, Bain JR, Trimmer JK, Brosnan MJ, Rolph TP, Newgard CB.

Mol Metab. 2016 Apr 22;5(7):538-551. doi: 10.1016/j.molmet.2016.04.006. eCollection 2016 Jul.

27.

Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling.

Quintana MT, Parry TL, He J, Yates CC, Sidorova TN, Murray KT, Bain JR, Newgard CB, Muehlbauer MJ, Eaton SC, Hishiya A, Takayama S, Willis MS.

Am J Pathol. 2016 Aug;186(8):1989-2007. doi: 10.1016/j.ajpath.2016.03.017. Epub 2016 Jun 17.

28.

Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth.

Scholtens DM, Bain JR, Reisetter AC, Muehlbauer MJ, Nodzenski M, Stevens RD, Ilkayeva O, Lowe LP, Metzger BE, Newgard CB, Lowe WL Jr; HAPO Study Cooperative Research Group.

Diabetes. 2016 Jul;65(7):2039-50. doi: 10.2337/db15-1748. Epub 2016 Apr 5.

29.

Proteomic Profiling Reveals Adaptive Responses to Surgical Myocardial Ischemia-Reperfusion in Hibernating Arctic Ground Squirrels Compared to Rats.

Quinones QJ, Zhang Z, Ma Q, Smith MP, Soderblom E, Moseley MA, Bain J, Newgard CB, Muehlbauer MJ, Hirschey M, Drew KL, Barnes BM, Podgoreanu MV.

Anesthesiology. 2016 Jun;124(6):1296-310. doi: 10.1097/ALN.0000000000001113.

30.

Human amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo.

Ilaiwy A, Liu M, Parry TL, Bain JR, Newgard CB, Schisler JC, Muehlbauer MJ, Despa F, Willis MS.

Metabolomics. 2016 May;12(5). pii: 95. doi: 10.1007/s11306-016-1022-9. Epub 2016 Apr 23.

31.

Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition.

Charbonneau MR, O'Donnell D, Blanton LV, Totten SM, Davis JC, Barratt MJ, Cheng J, Guruge J, Talcott M, Bain JR, Muehlbauer MJ, Ilkayeva O, Wu C, Struckmeyer T, Barile D, Mangani C, Jorgensen J, Fan YM, Maleta K, Dewey KG, Ashorn P, Newgard CB, Lebrilla C, Mills DA, Gordon JI.

Cell. 2016 Feb 25;164(5):859-71. doi: 10.1016/j.cell.2016.01.024. Epub 2016 Feb 18.

32.

Non-targeted metabolomics of Brg1/Brm double-mutant cardiomyocytes reveals a novel role for SWI/SNF complexes in metabolic homeostasis.

Banerjee R, Bultman SJ, Holley D, Hillhouse C, Bain JR, Newgard CB, Muehlbauer MJ, Willis MS.

Metabolomics. 2015 Oct 1;11(5):1287-1301.

33.

Macronutrient Regulation of Ghrelin and Peptide YY in Pediatric Obesity and Prader-Willi Syndrome.

Gumus Balikcioglu P, Balikcioglu M, Muehlbauer MJ, Purnell JQ, Broadhurst D, Freemark M, Haqq AM.

J Clin Endocrinol Metab. 2015 Oct;100(10):3822-31. doi: 10.1210/jc.2015-2503. Epub 2015 Aug 10.

34.

Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans.

Glynn EL, Piner LW, Huffman KM, Slentz CA, Elliot-Penry L, AbouAssi H, White PJ, Bain JR, Muehlbauer MJ, Ilkayeva OR, Stevens RD, Porter Starr KN, Bales CW, Volpi E, Brosnan MJ, Trimmer JK, Rolph TP, Newgard CB, Kraus WE.

Diabetologia. 2015 Oct;58(10):2324-35. doi: 10.1007/s00125-015-3705-6. Epub 2015 Aug 9.

35.

MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet.

He J, Quintana MT, Sullivan J, L Parry T, J Grevengoed T, Schisler JC, Hill JA, Yates CC, Mapanga RF, Essop MF, Stansfield WE, Bain JR, Newgard CB, Muehlbauer MJ, Han Y, Clarke BA, Willis MS.

Cardiovasc Diabetol. 2015 Aug 5;14:97. doi: 10.1186/s12933-015-0252-x.

36.

Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet.

Quintana MT, He J, Sullivan J, Grevengoed T, Schisler J, Han Y, Hill JA, Yates CC, Stansfield WE, Mapanga RF, Essop MF, Muehlbauer MJ, Newgard CB, Bain JR, Willis MS.

BMC Endocr Disord. 2015 Jul 28;15:36. doi: 10.1186/s12902-015-0028-z.

37.

Non-targeted metabolomics analysis of cardiac Muscle Ring Finger-1 (MuRF1), MuRF2, and MuRF3 in vivo reveals novel and redundant metabolic changes.

Banerjee R, He J, Spaniel C, Quintana MT, Wang Z, Bain J, Newgard CB, Muehlbauer MJ, Willis MS.

Metabolomics. 2015 Apr;11(2):312-322. doi: 10.1007/s11306-014-0695-1. Epub 2014 Jul 14.

38.

Metabomxtr: an R package for mixture-model analysis of non-targeted metabolomics data.

Nodzenski M, Muehlbauer MJ, Bain JR, Reisetter AC, Lowe WL Jr, Scholtens DM.

Bioinformatics. 2014 Nov 15;30(22):3287-8. doi: 10.1093/bioinformatics/btu509. Epub 2014 Jul 29.

39.

A transcription factor links growth rate and metabolism in the hypersaline adapted archaeon Halobacterium salinarum.

Todor H, Dulmage K, Gillum N, Bain JR, Muehlbauer MJ, Schmid AK.

Mol Microbiol. 2014 Sep;93(6):1172-82. doi: 10.1111/mmi.12726. Epub 2014 Aug 11.

40.

Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.

Tan M, Peng C, Anderson KA, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, Ro J, Wagner GR, Green MF, Madsen AS, Schmiesing J, Peterson BS, Xu G, Ilkayeva OR, Muehlbauer MJ, Braulke T, Mühlhausen C, Backos DS, Olsen CA, McGuire PJ, Pletcher SD, Lombard DB, Hirschey MD, Zhao Y.

Cell Metab. 2014 Apr 1;19(4):605-17. doi: 10.1016/j.cmet.2014.03.014.

41.

Race and sex differences in small-molecule metabolites and metabolic hormones in overweight and obese adults.

Patel MJ, Batch BC, Svetkey LP, Bain JR, Turer CB, Haynes C, Muehlbauer MJ, Stevens RD, Newgard CB, Shah SH.

OMICS. 2013 Dec;17(12):627-35. doi: 10.1089/omi.2013.0031. Epub 2013 Oct 11.

42.

Gut microbiota from twins discordant for obesity modulate metabolism in mice.

Ridaura VK, Faith JJ, Rey FE, Cheng J, Duncan AE, Kau AL, Griffin NW, Lombard V, Henrissat B, Bain JR, Muehlbauer MJ, Ilkayeva O, Semenkovich CF, Funai K, Hayashi DK, Lyle BJ, Martini MC, Ursell LK, Clemente JC, Van Treuren W, Walters WA, Knight R, Newgard CB, Heath AC, Gordon JI.

Science. 2013 Sep 6;341(6150):1241214. doi: 10.1126/science.1241214.

43.

Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy.

Scholtens DM, Muehlbauer MJ, Daya NR, Stevens RD, Dyer AR, Lowe LP, Metzger BE, Newgard CB, Bain JR, Lowe WL Jr; HAPO Study Cooperative Research Group.

Diabetes Care. 2014;37(1):158-66. doi: 10.2337/dc13-0989. Epub 2013 Aug 29.

44.

Metabolomics reveals unexpected responses to oral glucose.

Bain JR, Muehlbauer MJ.

Diabetes. 2013 Aug;62(8):2651-3. doi: 10.2337/db13-0605. No abstract available.

45.

Postprandial metabolite profiles reveal differential nutrient handling after bariatric surgery compared with matched caloric restriction.

Khoo CM, Muehlbauer MJ, Stevens RD, Pamuklar Z, Chen J, Newgard CB, Torquati A.

Ann Surg. 2014 Apr;259(4):687-93. doi: 10.1097/SLA.0b013e318296633f.

46.

Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation.

Sampey BP, Freemerman AJ, Zhang J, Kuan PF, Galanko JA, O'Connell TM, Ilkayeva OR, Muehlbauer MJ, Stevens RD, Newgard CB, Brauer HA, Troester MA, Makowski L.

PLoS One. 2012;7(6):e38812. doi: 10.1371/journal.pone.0038812. Epub 2012 Jun 12.

47.

Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease.

Shah SH, Sun JL, Stevens RD, Bain JR, Muehlbauer MJ, Pieper KS, Haynes C, Hauser ER, Kraus WE, Granger CB, Newgard CB, Califf RM, Newby LK.

Am Heart J. 2012 May;163(5):844-850.e1. doi: 10.1016/j.ahj.2012.02.005.

PMID:
22607863
48.

Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial.

Huffman KM, Redman LM, Landerman LR, Pieper CF, Stevens RD, Muehlbauer MJ, Wenner BR, Bain JR, Kraus VB, Newgard CB, Ravussin E, Kraus WE.

PLoS One. 2012;7(4):e28190. doi: 10.1371/journal.pone.0028190. Epub 2012 Apr 16.

49.

Metabolic profiles predict adverse events after coronary artery bypass grafting.

Shah AA, Craig DM, Sebek JK, Haynes C, Stevens RC, Muehlbauer MJ, Granger CB, Hauser ER, Newby LK, Newgard CB, Kraus WE, Hughes GC, Shah SH.

J Thorac Cardiovasc Surg. 2012 Apr;143(4):873-8. doi: 10.1016/j.jtcvs.2011.09.070. Epub 2012 Feb 4.

50.

Deletion of CaMKK2 from the liver lowers blood glucose and improves whole-body glucose tolerance in the mouse.

Anderson KA, Lin F, Ribar TJ, Stevens RD, Muehlbauer MJ, Newgard CB, Means AR.

Mol Endocrinol. 2012 Feb;26(2):281-91. doi: 10.1210/me.2011-1299. Epub 2012 Jan 12.

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