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Items: 11

1.

ABT-165, a Dual Variable Domain Immunoglobulin (DVD-Ig) Targeting DLL4 and VEGF, Demonstrates Superior Efficacy and Favorable Safety Profiles in Preclinical Models.

Li Y, Hickson JA, Ambrosi DJ, Haasch DL, Foster-Duke KD, Eaton LJ, DiGiammarino EL, Panchal SC, Jiang F, Mudd SR, Zhang C, Akella SS, Gao W, Ralston SL, Naumovski L, Gu J, Morgan-Lappe SE.

Mol Cancer Ther. 2018 May;17(5):1039-1050. doi: 10.1158/1535-7163.MCT-17-0800. Epub 2018 Mar 28.

2.

Characterization of ABBV-221, a Tumor-Selective EGFR-Targeting Antibody Drug Conjugate.

Phillips AC, Boghaert ER, Vaidya KS, Falls HD, Mitten MJ, DeVries PJ, Benatuil L, Hsieh CM, Meulbroek JA, Panchal SC, Buchanan FG, Durbin KR, Voorbach MJ, Reuter DR, Mudd SR, Loberg LI, Ralston SL, Cao D, Gan HK, Scott AM, Reilly EB.

Mol Cancer Ther. 2018 Apr;17(4):795-805. doi: 10.1158/1535-7163.MCT-17-0710. Epub 2018 Feb 26.

3.

Molecular imaging in oncology drug development.

Mudd SR, Comley RA, Bergstrom M, Holen KD, Luo Y, Carme S, Fox GB, Martarello L, Beaver JD.

Drug Discov Today. 2017 Jan;22(1):140-147. doi: 10.1016/j.drudis.2016.09.020. Epub 2016 Sep 28. Review.

PMID:
27693713
4.

Image quality of Zr-89 PET imaging in the Siemens microPET Focus 220 preclinical scanner.

Bradshaw TJ, Voorbach MJ, Reuter DR, Giamis AM, Mudd SR, Beaver JD.

Mol Imaging Biol. 2016 Jun;18(3):377-85. doi: 10.1007/s11307-015-0903-z.

PMID:
26493052
5.

Monitoring tumor response to linifanib therapy with SPECT/CT using the integrin αvβ3-targeted radiotracer 99mTc-3P-RGD2.

Ji S, Zhou Y, Voorbach MJ, Shao G, Zhang Y, Fox GB, Albert DH, Luo Y, Liu S, Mudd SR.

J Pharmacol Exp Ther. 2013 Aug;346(2):251-8. doi: 10.1124/jpet.112.202622. Epub 2013 Jun 7.

6.

Application of a whole-body pharmacokinetic model for targeted radionuclide therapy to NM404 and FLT.

Grudzinski JJ, Floberg JM, Mudd SR, Jeffery JJ, Peterson ET, Nomura A, Burnette RR, Tomé WA, Weichert JP, Jeraj R.

Phys Med Biol. 2012 Mar 21;57(6):1641-57. doi: 10.1088/0031-9155/57/6/1641. Epub 2012 Mar 7.

7.

FDG-PET as a pharmacodynamic biomarker for early assessment of treatment response to linifanib (ABT-869) in a non-small cell lung cancer xenograft model.

Mudd SR, Voorbach MJ, Reuter DR, Tapang P, Hickson JA, Refici-Buhr M, Fox GB, Albert DH, Luo Y, Day M.

Cancer Chemother Pharmacol. 2012 Jun;69(6):1669-72. doi: 10.1007/s00280-012-1840-z. Epub 2012 Feb 12.

PMID:
22327787
8.

Pharmacodynamic evaluation of irinotecan therapy by FDG and FLT PET/CT imaging in a colorectal cancer xenograft model.

Mudd SR, Holich KD, Voorbach MJ, Cole TB, Reuter DR, Tapang P, Bukofzer G, Chakravartty A, Donawho CK, Palma JP, Fox GB, Day M, Luo Y.

Mol Imaging Biol. 2012 Oct;14(5):617-24. doi: 10.1007/s11307-011-0529-8.

PMID:
22167582
9.

Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: limitations as a translatable model of Alzheimer's disease.

Luo F, Rustay NR, Ebert U, Hradil VP, Cole TB, Llano DA, Mudd SR, Zhang Y, Fox GB, Day M.

Neurobiol Aging. 2012 May;33(5):933-44. doi: 10.1016/j.neurobiolaging.2010.08.005. Epub 2010 Oct 18.

PMID:
20961663
10.

Hybrid PET/CT for noninvasive pharmacokinetic evaluation of dynamic PolyConjugates, a synthetic siRNA delivery system.

Mudd SR, Trubetskoy VS, Blokhin AV, Weichert JP, Wolff JA.

Bioconjug Chem. 2010 Jul 21;21(7):1183-9. doi: 10.1021/bc900558z.

PMID:
20552976
11.

Reproducibility of tumor volume measurement at microCT colonography in living mice.

Durkee BY, Mudd SR, Roen CN, Clipson L, Newton MA, Weichert JP, Pickhardt PJ, Halberg RB.

Acad Radiol. 2008 Mar;15(3):334-41. doi: 10.1016/j.acra.2007.10.005.

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