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Items: 26

1.

Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance.

Vinton CL, Magaziner SJ, Dowd KA, Robertson SJ, Amaro-Carambot E, Karmele EP, Ortiz AM, Starke CE, Mudd JC, Whitehead SS, Best SM, Pierson TC, Hickman HD, Brenchley JM.

mBio. 2019 Dec 3;10(6). pii: e02790-19. doi: 10.1128/mBio.02790-19.

2.

SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues.

Starke CE, Vinton CL, Ladell K, McLaren JE, Ortiz AM, Mudd JC, Flynn JK, Lai SH, Wu F, Hirsch VM, Darko S, Douek DC, Price DA, Brenchley JM.

J Clin Invest. 2020 Feb 3;130(2):789-798. doi: 10.1172/JCI129161.

3.

Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence.

Pino M, Paganini S, Deleage C, Padhan K, Harper JL, King CT, Micci L, Cervasi B, Mudd JC, Gill KP, Jean SM, Easley K, Silvestri G, Estes JD, Petrovas C, Lederman MM, Paiardini M.

PLoS Pathog. 2019 Oct 18;15(10):e1008081. doi: 10.1371/journal.ppat.1008081. eCollection 2019 Oct.

4.

Innate Lymphoid Cells: Their Contributions to Gastrointestinal Tissue Homeostasis and HIV/SIV Disease Pathology.

Mudd JC, Brenchley JM.

Curr HIV/AIDS Rep. 2019 Jun;16(3):181-190. doi: 10.1007/s11904-019-00439-4. Review.

PMID:
31104270
5.

Simian Immunodeficiency Virus Infects Functionally Polarized Memory CD4 T Cells Equivalently In Vivo.

Lai SH, Starke CE, Flynn JK, Vinton CL, Ortiz AM, Mudd JC, Brenchley JM.

J Virol. 2019 Apr 17;93(9). pii: e02163-18. doi: 10.1128/JVI.02163-18. Print 2019 May 1.

6.

Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells.

Mudd JC, Busman-Sahay K, DiNapoli SR, Lai S, Sheik V, Lisco A, Deleage C, Richardson B, Palesch DJ, Paiardini M, Cameron M, Sereti I, Reeves RK, Estes JD, Brenchley JM.

Nat Commun. 2018 Sep 27;9(1):3967. doi: 10.1038/s41467-018-05528-3.

7.

Experimental microbial dysbiosis does not promote disease progression in SIV-infected macaques.

Ortiz AM, Flynn JK, DiNapoli SR, Vujkovic-Cvijin I, Starke CE, Lai SH, Long ME, Sortino O, Vinton CL, Mudd JC, Johnston L, Busman-Sahay K, Belkaid Y, Estes JD, Brenchley JM.

Nat Med. 2018 Sep;24(9):1313-1316. doi: 10.1038/s41591-018-0132-5. Epub 2018 Jul 30.

8.

Cytotoxic T Cell Functions Accumulate When CD4 Is Downregulated by CD4+ T Cells in African Green Monkeys.

Vinton CL, Ortiz AM, Calantone N, Mudd JC, Deleage C, Morcock DR, Whitted S, Estes JD, Hirsch VM, Brenchley JM.

J Immunol. 2017 Jun 1;198(11):4403-4412. doi: 10.4049/jimmunol.1700136. Epub 2017 Apr 24.

9.

Inflammatory Function of CX3CR1+ CD8+ T Cells in Treated HIV Infection Is Modulated by Platelet Interactions.

Mudd JC, Panigrahi S, Kyi B, Moon SH, Manion MM, Younes SA, Sieg SF, Funderburg NT, Zidar DA, Lederman MM, Freeman ML.

J Infect Dis. 2016 Dec 15;214(12):1808-1816. Epub 2016 Oct 4.

10.

Gut Mucosal Barrier Dysfunction, Microbial Dysbiosis, and Their Role in HIV-1 Disease Progression.

Mudd JC, Brenchley JM.

J Infect Dis. 2016 Oct 1;214 Suppl 2:S58-66. doi: 10.1093/infdis/jiw258.

11.

IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection.

Younes SA, Freeman ML, Mudd JC, Shive CL, Reynaldi A, Panigrahi S, Estes JD, Deleage C, Lucero C, Anderson J, Schacker TW, Davenport MP, McCune JM, Hunt PW, Lee SA, Serrano-Villar S, Debernardo RL, Jacobson JM, Canaday DH, Sekaly RP, Rodriguez B, Sieg SF, Lederman MM.

J Clin Invest. 2016 Jul 1;126(7):2745-56. doi: 10.1172/JCI85996. Epub 2016 Jun 20.

12.

Interleukin-2 Therapy Induces CD4 Downregulation, Which Decreases Circulating CD4 T Cell Counts, in African Green Monkeys.

Mudd JC, Perkins MR, DiNapoli SR, Hirsch VM, Brenchley JM.

J Virol. 2016 May 27;90(12):5750-5758. doi: 10.1128/JVI.00057-16. Print 2016 Jun 15.

13.

Reply to Barrett, et al.

Freeman ML, Mudd JC, Shive CL, Younes SA, Panigrahi S, Sieg SF, Lee SA, Hunt PW, Calabrese LH, Gianella S, Rodriguez B, Lederman MM.

Clin Infect Dis. 2016 Jun 1;62(11):1468-9. doi: 10.1093/cid/ciw152. Epub 2016 Mar 21. No abstract available.

14.

ILC You Later: Early and Irreparable Loss of Innate Lymphocytes in HIV Infection.

Mudd JC, Brenchley JM.

Immunity. 2016 Feb 16;44(2):216-8. doi: 10.1016/j.immuni.2016.01.022.

15.

SIV/SHIV Infection Triggers Vascular Inflammation, Diminished Expression of Krüppel-like Factor 2 and Endothelial Dysfunction.

Panigrahi S, Freeman ML, Funderburg NT, Mudd JC, Younes SA, Sieg SF, Zidar DA, Paiardini M, Villinger F, Calabrese LH, Ransohoff RM, Jain MK, Lederman MM.

J Infect Dis. 2016 May 1;213(9):1419-27. doi: 10.1093/infdis/jiv749. Epub 2015 Dec 15.

16.

Altered Maturation Status and Possible Immune Exhaustion of CD8 T Lymphocytes in the Peripheral Blood of Patients Presenting With Acute Coronary Syndromes.

Zidar DA, Mudd JC, Juchnowski S, Lopes JP, Sparks S, Park SS, Ishikawa M, Osborne R, Washam JB, Chan C, Funderburg NT, Owoyele A, Alaiti MA, Mayuga M, Orringer C, Costa MA, Simon DI, Tatsuoka C, Califf RM, Newby LK, Lederman MM, Weinhold KJ.

Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):389-97. doi: 10.1161/ATVBAHA.115.306112. Epub 2015 Dec 10.

17.

Inflammation Perturbs the IL-7 Axis, Promoting Senescence and Exhaustion that Broadly Characterize Immune Failure in Treated HIV Infection.

Shive CL, Clagett B, McCausland MR, Mudd JC, Funderburg NT, Freeman ML, Younes SA, Ferrari BM, Rodriguez B, McComsey GA, Calabrese LH, Sieg SF, Lederman MM.

J Acquir Immune Defic Syndr. 2016 Apr 15;71(5):483-92. doi: 10.1097/QAI.0000000000000913.

18.

CD8 T-Cell Expansion and Inflammation Linked to CMV Coinfection in ART-treated HIV Infection.

Freeman ML, Mudd JC, Shive CL, Younes SA, Panigrahi S, Sieg SF, Lee SA, Hunt PW, Calabrese LH, Gianella S, Rodriguez B, Lederman MM.

Clin Infect Dis. 2016 Feb 1;62(3):392-6. doi: 10.1093/cid/civ840. Epub 2015 Sep 23.

19.

Interferon-α inhibits CD4 T cell responses to interleukin-7 and interleukin-2 and selectively interferes with Akt signaling.

Nguyen TP, Bazdar DA, Mudd JC, Lederman MM, Harding CV, Hardy GA, Sieg SF.

J Leukoc Biol. 2015 Jun;97(6):1139-46. doi: 10.1189/jlb.4A0714-345RR. Epub 2015 Mar 17.

20.

Dysbiotic bacteria translocate in progressive SIV infection.

Klase Z, Ortiz A, Deleage C, Mudd JC, Quiñones M, Schwartzman E, Klatt NR, Canary L, Estes JD, Brenchley JM.

Mucosal Immunol. 2015 Sep;8(5):1009-20. doi: 10.1038/mi.2014.128. Epub 2015 Jan 14.

21.

CD8 T cell persistence in treated HIV infection.

Mudd JC, Lederman MM.

Curr Opin HIV AIDS. 2014 Sep;9(5):500-5. doi: 10.1097/COH.0000000000000086. Review.

22.

Inflammatory cytokines drive CD4+ T-cell cycling and impaired responsiveness to interleukin 7: implications for immune failure in HIV disease.

Shive CL, Mudd JC, Funderburg NT, Sieg SF, Kyi B, Bazdar DA, Mangioni D, Gori A, Jacobson JM, Brooks AD, Hardacre J, Ammori J, Estes JD, Schacker TW, Rodriguez B, Lederman MM.

J Infect Dis. 2014 Aug 15;210(4):619-29. doi: 10.1093/infdis/jiu125. Epub 2014 Feb 28.

23.

Cycling memory CD4+ T cells in HIV disease have a diverse T cell receptor repertoire and a phenotype consistent with bystander activation.

Jiang W, Younes SA, Funderburg NT, Mudd JC, Espinosa E, Davenport MP, Babineau DC, Sieg SF, Lederman MM.

J Virol. 2014 May;88(10):5369-80. doi: 10.1128/JVI.00017-14. Epub 2014 Feb 12.

24.

Inadequate T follicular cell help impairs B cell immunity during HIV infection.

Cubas RA, Mudd JC, Savoye AL, Perreau M, van Grevenynghe J, Metcalf T, Connick E, Meditz A, Freeman GJ, Abesada-Terk G Jr, Jacobson JM, Brooks AD, Crotty S, Estes JD, Pantaleo G, Lederman MM, Haddad EK.

Nat Med. 2013 Apr;19(4):494-9. doi: 10.1038/nm.3109. Epub 2013 Mar 10.

25.

Impaired T-cell responses to sphingosine-1-phosphate in HIV-1 infected lymph nodes.

Mudd JC, Murphy P, Manion M, Debernardo R, Hardacre J, Ammori J, Hardy GA, Harding CV, Mahabaleshwar GH, Jain MK, Jacobson JM, Brooks AD, Lewis S, Schacker TW, Anderson J, Haddad EK, Cubas RA, Rodriguez B, Sieg SF, Lederman MM.

Blood. 2013 Apr 11;121(15):2914-22. doi: 10.1182/blood-2012-07-445783. Epub 2013 Feb 19.

26.

Down-regulation of serum gonadotropins is as effective as estrogen replacement at improving menopause-associated cognitive deficits.

Bryan KJ, Mudd JC, Richardson SL, Chang J, Lee HG, Zhu X, Smith MA, Casadesus G.

J Neurochem. 2010 Feb;112(4):870-81. doi: 10.1111/j.1471-4159.2009.06502.x. Epub 2009 Nov 24.

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