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Items: 29

1.

Structural and biochemical insights into an engineered high-redox potential laccase overproduced in Aspergillus.

de Salas F, Cañadas R, Santiago G, Virseda-Jerez A, Vind J, Gentili P, Martínez AT, Guallar V, Muñoz IG, Camarero S.

Int J Biol Macromol. 2019 Sep 7. pii: S0141-8130(19)35319-X. doi: 10.1016/j.ijbiomac.2019.09.052. [Epub ahead of print]

2.

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity.

Compte M, Harwood SL, Muñoz IG, Navarro R, Zonca M, Perez-Chacon G, Erce-Llamazares A, Merino N, Tapia-Galisteo A, Cuesta AM, Mikkelsen K, Caleiras E, Nuñez-Prado N, Aznar MA, Lykkemark S, Martínez-Torrecuadrada J, Melero I, Blanco FJ, Bernardino de la Serna J, Zapata JM, Sanz L, Alvarez-Vallina L.

Nat Commun. 2018 Nov 15;9(1):4809. doi: 10.1038/s41467-018-07195-w.

3.

Molecular basis of Tousled-Like Kinase 2 activation.

Mortuza GB, Hermida D, Pedersen AK, Segura-Bayona S, López-Méndez B, Redondo P, Rüther P, Pozdnyakova I, Garrote AM, Muñoz IG, Villamor-Payà M, Jauset C, Olsen JV, Stracker TH, Montoya G.

Nat Commun. 2018 Jun 28;9(1):2535. doi: 10.1038/s41467-018-04941-y.

4.

The Population Education Transition Curve: Education Gradients Across Population Exposure to New Health Risks.

Baker DP, Smith WC, Muñoz IG, Jeon H, Fu T, Leon J, Salinas D, Horvatek R.

Demography. 2017 Oct;54(5):1873-1895. doi: 10.1007/s13524-017-0608-9.

PMID:
28875332
5.

A mechanism for cancer-associated inactivation of NQO1 due to P187S and its reactivation by the consensus mutation H80R.

Muñoz IG, Morel B, Medina-Carmona E, Pey AL.

FEBS Lett. 2017 Sep;591(18):2826-2835. doi: 10.1002/1873-3468.12772. Epub 2017 Aug 20.

6.

Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells.

Wu W, Xu C, Ling X, Fan C, Buckley BP, Chernov MV, Ellis L, Li F, Muñoz IG, Wang X.

Cell Death Dis. 2015 Dec 31;6:e2035. doi: 10.1038/cddis.2015.358.

7.

Structural basis of PcsB-mediated cell separation in Streptococcus pneumoniae.

Bartual SG, Straume D, Stamsås GA, Muñoz IG, Alfonso C, Martínez-Ripoll M, Håvarstein LS, Hermoso JA.

Nat Commun. 2014 May 8;5:3842. doi: 10.1038/ncomms4842.

8.

Purification, crystallization and preliminary X-ray diffraction analysis of the kinase domain of human tousled-like kinase 2.

Garrote AM, Redondo P, Montoya G, Muñoz IG.

Acta Crystallogr F Struct Biol Commun. 2014 Mar;70(Pt 3):354-7. doi: 10.1107/S2053230X14002581. Epub 2014 Feb 19.

9.

Crystal structure of inhibitor of growth 4 (ING4) dimerization domain reveals functional organization of ING family of chromatin-binding proteins.

Culurgioni S, Muñoz IG, Moreno A, Palacios A, Villate M, Palmero I, Montoya G, Blanco FJ.

J Biol Chem. 2012 Mar 30;287(14):10876-84. doi: 10.1074/jbc.M111.330001. Epub 2012 Feb 9.

10.

Kinetics in signal transduction pathways involving promiscuous oligomerizing receptors can be determined by receptor specificity: apoptosis induction by TRAIL.

Szegezdi E, van der Sloot AM, Mahalingam D, O'Leary L, Cool RH, Muñoz IG, Montoya G, Quax WJ, de Jong S, Samali A, Serrano L.

Mol Cell Proteomics. 2012 Mar;11(3):M111.013730. doi: 10.1074/mcp.M111.013730. Epub 2012 Jan 2.

11.

Chaperonins: two rings for folding.

Yébenes H, Mesa P, Muñoz IG, Montoya G, Valpuesta JM.

Trends Biochem Sci. 2011 Aug;36(8):424-32. doi: 10.1016/j.tibs.2011.05.003. Epub 2011 Jun 30. Review.

PMID:
21723731
12.

Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin.

Muñoz IG, Yébenes H, Zhou M, Mesa P, Serna M, Park AY, Bragado-Nilsson E, Beloso A, de Cárcer G, Malumbres M, Robinson CV, Valpuesta JM, Montoya G.

Nat Struct Mol Biol. 2011 Jan;18(1):14-9. doi: 10.1038/nsmb.1971. Epub 2010 Dec 12.

PMID:
21151115
13.

Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.

Muñoz IG, Prieto J, Subramanian S, Coloma J, Redondo P, Villate M, Merino N, Marenchino M, D'Abramo M, Gervasio FL, Grizot S, Daboussi F, Smith J, Chion-Sotinel I, Pâques F, Duchateau P, Alibés A, Stricher F, Serrano L, Blanco FJ, Montoya G.

Nucleic Acids Res. 2011 Jan;39(2):729-43. doi: 10.1093/nar/gkq801. Epub 2010 Sep 16.

14.

Crystallization and preliminary X-ray diffraction analysis of the dimerization domain of the tumour suppressor ING4.

Culurgioni S, Muñoz IG, Palacios A, Redondo P, Blanco FJ, Montoya G.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1;66(Pt 5):567-70. doi: 10.1107/S1744309110010080. Epub 2010 Apr 30.

15.

Homing endonucleases: from basics to therapeutic applications.

Marcaida MJ, Muñoz IG, Blanco FJ, Prieto J, Montoya G.

Cell Mol Life Sci. 2010 Mar;67(5):727-48. doi: 10.1007/s00018-009-0188-y. Review.

PMID:
19915993
16.

Activation of nucleoplasmin, an oligomeric histone chaperone, challenges its stability.

Taneva SG, Muñoz IG, Franco G, Falces J, Arregi I, Muga A, Montoya G, Urbaneja MA, Bañuelos S.

Biochemistry. 2008 Dec 30;47(52):13897-906. doi: 10.1021/bi800975r.

PMID:
19055325
17.

Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases.

Redondo P, Prieto J, Muñoz IG, Alibés A, Stricher F, Serrano L, Cabaniols JP, Daboussi F, Arnould S, Perez C, Duchateau P, Pâques F, Blanco FJ, Montoya G.

Nature. 2008 Nov 6;456(7218):107-11. doi: 10.1038/nature07343.

PMID:
18987743
18.

On the relevance of defining protein structures in cancer research.

Muñoz IG, Blanco FJ, Montoya G.

Clin Transl Oncol. 2008 Apr;10(4):204-12. Review.

PMID:
18411193
19.

Molecular basis of histone H3K4me3 recognition by ING4.

Palacios A, Muñoz IG, Pantoja-Uceda D, Marcaida MJ, Torres D, Martín-García JM, Luque I, Montoya G, Blanco FJ.

J Biol Chem. 2008 Jun 6;283(23):15956-64. doi: 10.1074/jbc.M710020200. Epub 2008 Apr 1.

20.

Crystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domain.

Rodamilans B, Muñoz IG, Bragado-Nilsson E, Sarrias MR, Padilla O, Blanco FJ, Lozano F, Montoya G.

J Biol Chem. 2007 Apr 27;282(17):12669-77. Epub 2007 Feb 23.

21.

Ischemia induces nuclear NOX2 expression in cardiomyocytes and subsequently activates apoptosis.

Meischl C, Krijnen PA, Sipkens JA, Cillessen SA, Muñoz IG, Okroj M, Ramska M, Muller A, Visser CA, Musters RJ, Simonides WS, Hack CE, Roos D, Niessen HW.

Apoptosis. 2006 Jun;11(6):913-21.

PMID:
16544099
22.

Three-dimensional crystal structure and enzymic characterization of beta-mannanase Man5A from blue mussel Mytilus edulis.

Larsson AM, Anderson L, Xu B, Muñoz IG, Usón I, Janson JC, Stålbrand H, Ståhlberg J.

J Mol Biol. 2006 Apr 14;357(5):1500-10. Epub 2006 Jan 31.

PMID:
16487541
23.

Structures of Phanerochaete chrysosporium Cel7D in complex with product and inhibitors.

Ubhayasekera W, Muñoz IG, Vasella A, Ståhlberg J, Mowbray SL.

FEBS J. 2005 Apr;272(8):1952-64.

24.
25.

Relationship between psychological complaints and vasomotor symptoms during climacteric.

Blümel JE, Castelo-Branco C, Cancelo MJ, Córdova AT, Binfa LE, Bonilla HG, Muñoz IG, Vergara VG, Sarrá SC.

Maturitas. 2004 Nov 15;49(3):205-10.

PMID:
15488348
26.

Crystallization and preliminary X-ray diffraction studies of the eukaryotic iron superoxide dismutase (FeSOD) from Vigna unguiculata.

Muñoz IG, Moran JF, Becana M, Montoya G.

Acta Crystallogr D Biol Crystallogr. 2003 Jun;59(Pt 6):1070-2. Epub 2003 May 23.

PMID:
12777777
27.

The catalytic module of Cel7D from Phanerochaete chrysosporium as a chiral selector: structural studies of its complex with the beta blocker (R)-propranolol.

Muñoz IG, Mowbray SL, Ståhlberg J.

Acta Crystallogr D Biol Crystallogr. 2003 Apr;59(Pt 4):637-43. Epub 2003 Mar 25.

PMID:
12657782
28.

Family 7 cellobiohydrolases from Phanerochaete chrysosporium: crystal structure of the catalytic module of Cel7D (CBH58) at 1.32 A resolution and homology models of the isozymes.

Muñoz IG, Ubhayasekera W, Henriksson H, Szabó I, Pettersson G, Johansson G, Mowbray SL, Ståhlberg J.

J Mol Biol. 2001 Dec 14;314(5):1097-111.

PMID:
11743726
29.

Cellobiohydrolase 58 (P.c. Cel 7D) is complementary to the homologous CBH I (T.r. Cel 7A) in enantioseparations.

Henriksson H, Muñoz IG, Isaksson R, Pettersson G, Johansson G.

J Chromatogr A. 2000 Nov 10;898(1):63-74.

PMID:
11185624

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