Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 164

1.

High-throughput mapping of CoA metabolites by SAMDI-MS to optimize the cell-free biosynthesis of HMG-CoA.

O'Kane PT, Dudley QM, McMillan AK, Jewett MC, Mrksich M.

Sci Adv. 2019 Jun 5;5(6):eaaw9180. doi: 10.1126/sciadv.aaw9180. eCollection 2019 Jun.

2.

Storage of Information Using Small Organic Molecules.

Cafferty BJ, Ten AS, Fink MJ, Morey S, Preston DJ, Mrksich M, Whitesides GM.

ACS Cent Sci. 2019 May 22;5(5):911-916. doi: 10.1021/acscentsci.9b00210. Epub 2019 May 1.

3.

Dynamic Substrates for Cell Biology.

Bugga P, Mrksich M.

Curr Opin Colloid Interface Sci. 2018 Nov;38:80-87. doi: 10.1016/j.cocis.2018.09.003. Epub 2018 Sep 29.

PMID:
31011283
4.

Exploration of the nanomedicine-design space with high-throughput screening and machine learning.

Yamankurt G, Berns EJ, Xue A, Lee A, Bagheri N, Mrksich M, Mirkin CA.

Nat Biomed Eng. 2019 Apr;3(4):318-327. doi: 10.1038/s41551-019-0351-1. Epub 2019 Feb 18.

5.

Sequential Photoactivation of Self-Assembled Monolayers to Direct Cell Adhesion and Migration.

Bugga P, Mrksich M.

Langmuir. 2019 Apr 30;35(17):5937-5943. doi: 10.1021/acs.langmuir.8b04203. Epub 2019 Apr 15.

PMID:
30943037
6.

Using Microfluidics and Imaging SAMDI-MS To Characterize Reaction Kinetics.

Grant J, O'Kane PT, Kimmel BR, Mrksich M.

ACS Cent Sci. 2019 Mar 27;5(3):486-493. doi: 10.1021/acscentsci.8b00867. Epub 2019 Feb 12.

7.

Using Peptide Arrays To Discover the Sequence-Specific Acetylation of the Histidine-Tyrosine Dyad.

Szymczak LC, Mrksich M.

Biochemistry. 2019 Apr 2;58(13):1810-1817. doi: 10.1021/acs.biochem.9b00022. Epub 2019 Mar 12.

PMID:
30817132
8.

Photoactivatable Reaction for Covalent Nanoscale Patterning of Multiple Proteins.

Zhou S, Metcalf KJ, Bugga P, Grant J, Mrksich M.

ACS Appl Mater Interfaces. 2018 Nov 28;10(47):40452-40459. doi: 10.1021/acsami.8b16736. Epub 2018 Nov 14.

PMID:
30379516
9.

Long-Range Energy Transfer in Protein Megamolecules.

Taylor EL, Metcalf KJ, Carlotti B, Lai CT, Modica JA, Schatz GC, Mrksich M, Goodson T 3rd.

J Am Chem Soc. 2018 Nov 21;140(46):15731-15743. doi: 10.1021/jacs.8b08208. Epub 2018 Nov 9.

PMID:
30375862
10.

High-Throughput Enzyme Kinetics with 3D Microfluidics and Imaging SAMDI Mass Spectrometry.

Grant J, Goudarzi SH, Mrksich M.

Anal Chem. 2018 Nov 6;90(21):13096-13103. doi: 10.1021/acs.analchem.8b04391. Epub 2018 Oct 10.

PMID:
30257085
11.

Combining SAMDI Mass Spectrometry and Peptide Arrays to Profile Phosphatase Activities.

Szymczak LC, Huang CF, Berns EJ, Mrksich M.

Methods Enzymol. 2018;607:389-403. doi: 10.1016/bs.mie.2018.04.021. Epub 2018 Jun 19.

12.

Author Correction: Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.

Jaroentomeechai T, Stark JC, Natarajan A, Glasscock CJ, Yates LE, Hsu KJ, Mrksich M, Jewett MC, DeLisa MP.

Nat Commun. 2018 Aug 20;9(1):3396. doi: 10.1038/s41467-018-05620-8.

13.

Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.

Jaroentomeechai T, Stark JC, Natarajan A, Glasscock CJ, Yates LE, Hsu KJ, Mrksich M, Jewett MC, DeLisa MP.

Nat Commun. 2018 Jul 12;9(1):2686. doi: 10.1038/s41467-018-05110-x. Erratum in: Nat Commun. 2018 Aug 20;9(1):3396.

14.

An Immobilized Enzyme Reactor for Spatiotemporal Control over Reaction Products.

Grant J, Modica JA, Roll J, Perkovich P, Mrksich M.

Small. 2018 Jul 3:e1800923. doi: 10.1002/smll.201800923. [Epub ahead of print]

PMID:
29971942
15.

Traceless Immobilization of Analytes for High-Throughput Experiments with SAMDI Mass Spectrometry.

Helal KY, Alamgir A, Berns EJ, Mrksich M.

J Am Chem Soc. 2018 Jul 5;140(26):8060-8063. doi: 10.1021/jacs.8b02918. Epub 2018 Jun 21.

16.

Potent laminin-inspired antioxidant regenerative dressing accelerates wound healing in diabetes.

Zhu Y, Cankova Z, Iwanaszko M, Lichtor S, Mrksich M, Ameer GA.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6816-6821. doi: 10.1073/pnas.1804262115. Epub 2018 Jun 11.

17.

An Unusual Salt Effect in an Interfacial Nucleophilic Substitution Reaction.

Li S, Mrksich M.

Langmuir. 2018 Jun 12;34(23):6713-6718. doi: 10.1021/acs.langmuir.8b00875. Epub 2018 May 31.

PMID:
29772172
18.

Design of glycosylation sites by rapid synthesis and analysis of glycosyltransferases.

Kightlinger W, Lin L, Rosztoczy M, Li W, DeLisa MP, Mrksich M, Jewett MC.

Nat Chem Biol. 2018 Jun;14(6):627-635. doi: 10.1038/s41589-018-0051-2. Epub 2018 May 7.

PMID:
29736039
19.

Synthesis of Cyclic Megamolecules.

Modica JA, Lin Y, Mrksich M.

J Am Chem Soc. 2018 May 23;140(20):6391-6399. doi: 10.1021/jacs.8b02665. Epub 2018 May 15.

PMID:
29723476
20.

How many human proteoforms are there?

Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P, Mootha VK, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE, Vidal M, Walt DR, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B.

Nat Chem Biol. 2018 Feb 14;14(3):206-214. doi: 10.1038/nchembio.2576.

21.

Peptide delivery with poly(ethylene glycol) diacrylate microneedles through swelling effect.

Liu S, Yeo DC, Wiraja C, Tey HL, Mrksich M, Xu C.

Bioeng Transl Med. 2017 Jul 14;2(3):258-267. doi: 10.1002/btm2.10070. eCollection 2017 Sep.

22.

Peptide Arrays: Development and Application.

Szymczak LC, Kuo HY, Mrksich M.

Anal Chem. 2018 Jan 2;90(1):266-282. doi: 10.1021/acs.analchem.7b04380. Epub 2017 Dec 5. Review. No abstract available.

23.

A Bottom-Up Proteomic Approach to Identify Substrate Specificity of Outer-Membrane Protease OmpT.

Wood SE, Sinsinbar G, Gudlur S, Nallani M, Huang CF, Liedberg B, Mrksich M.

Angew Chem Int Ed Engl. 2017 Dec 22;56(52):16531-16535. doi: 10.1002/anie.201707535. Epub 2017 Oct 10.

PMID:
28940795
24.

Active Site Metal Identity Alters Histone Deacetylase 8 Substrate Selectivity: A Potential Novel Regulatory Mechanism.

Castaneda CA, Lopez JE, Joseph CG, Scholle MD, Mrksich M, Fierke CA.

Biochemistry. 2017 Oct 24;56(42):5663-5670. doi: 10.1021/acs.biochem.7b00851. Epub 2017 Oct 12.

25.

Machine Learning on Signal-to-Noise Ratios Improves Peptide Array Design in SAMDI Mass Spectrometry.

Xue AY, Szymczak LC, Mrksich M, Bagheri N.

Anal Chem. 2017 Sep 5;89(17):9039-9047. doi: 10.1021/acs.analchem.7b01728. Epub 2017 Aug 7.

26.

An Assay Based on SAMDI Mass Spectrometry for Profiling Protein Interaction Domains.

O'Kane PT, Mrksich M.

J Am Chem Soc. 2017 Aug 2;139(30):10320-10327. doi: 10.1021/jacs.7b03805. Epub 2017 Jul 21.

PMID:
28689418
27.

Nanopatterned Extracellular Matrices Enable Cell-Based Assays with a Mass Spectrometric Readout.

Cabezas MD, Mirkin CA, Mrksich M.

Nano Lett. 2017 Mar 8;17(3):1373-1377. doi: 10.1021/acs.nanolett.6b04176. Epub 2017 Feb 7.

28.

Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase.

Raji I, Yadudu F, Janeira E, Fathi S, Szymczak L, Kornacki JR, Komatsu K, Li JD, Mrksich M, Oyelere AK.

Bioorg Med Chem. 2017 Feb 1;25(3):1202-1218. doi: 10.1016/j.bmc.2016.12.032. Epub 2016 Dec 24.

29.

Bisboronic Acids for Selective, Physiologically Relevant Direct Glucose Sensing with Surface-Enhanced Raman Spectroscopy.

Sharma B, Bugga P, Madison LR, Henry AI, Blaber MG, Greeneltch NG, Chiang N, Mrksich M, Schatz GC, Van Duyne RP.

J Am Chem Soc. 2016 Oct 26;138(42):13952-13959. doi: 10.1021/jacs.6b07331. Epub 2016 Oct 11.

PMID:
27668444
30.

Measuring Drug Metabolism Kinetics and Drug-Drug Interactions Using Self-Assembled Monolayers for Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry.

Anderson LL, Berns EJ, Bugga P, George AL Jr, Mrksich M.

Anal Chem. 2016 Sep 6;88(17):8604-9. doi: 10.1021/acs.analchem.6b01750. Epub 2016 Aug 12.

PMID:
27467208
31.

Cell-Based Screening: Cellular Assays with a Molecular Endpoint Measured by SAMDI Mass Spectrometry (Small 28/2016).

Berns EJ, Cabezas MD, Mrksich M.

Small. 2016 Jul;12(28):3810. doi: 10.1002/smll.201670138.

PMID:
27439735
32.

Cellular Assays with a Molecular Endpoint Measured by SAMDI Mass Spectrometry.

Berns EJ, Cabezas MD, Mrksich M.

Small. 2016 Jul;12(28):3811-8. doi: 10.1002/smll.201502940. Epub 2016 May 30.

33.

Micropatterning Facilitates the Long-Term Growth and Analysis of iPSC-Derived Individual Human Neurons and Neuronal Networks.

Burbulla LF, Beaumont KG, Mrksich M, Krainc D.

Adv Healthc Mater. 2016 Aug;5(15):1894-903. doi: 10.1002/adhm.201500900. Epub 2016 Apr 24.

34.

SIRT1 is a critical regulator of K562 cell growth, survival, and differentiation.

Duncan MT, DeLuca TA, Kuo HY, Yi M, Mrksich M, Miller WM.

Exp Cell Res. 2016 May 15;344(1):40-52. doi: 10.1016/j.yexcr.2016.04.010. Epub 2016 Apr 13.

35.

A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities.

Tapadar S, Fathi S, Raji I, Omesiete W, Kornacki JR, Mwakwari SC, Miyata M, Mitsutake K, Li JD, Mrksich M, Oyelere AK.

Bioorg Med Chem. 2015 Dec 15;23(24):7543-64. doi: 10.1016/j.bmc.2015.10.045. Epub 2015 Nov 2.

36.

SAMDI Mass Spectrometry-Enabled High-Throughput Optimization of a Traceless Petasis Reaction.

Diagne AB, Li S, Perkowski GA, Mrksich M, Thomson RJ.

ACS Comb Sci. 2015 Nov 9;17(11):658-62. doi: 10.1021/acscombsci.5b00131. Epub 2015 Nov 1.

PMID:
26521847
37.

Discovery of SIRT3 Inhibitors Using SAMDI Mass Spectrometry.

Patel K, Sherrill J, Mrksich M, Scholle MD.

J Biomol Screen. 2015 Aug;20(7):842-8. doi: 10.1177/1087057115588512. Epub 2015 May 29.

PMID:
26024947
38.

Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids.

Sodji QH, Kornacki JR, McDonald JF, Mrksich M, Oyelere AK.

Eur J Med Chem. 2015;96:340-59. doi: 10.1016/j.ejmech.2015.04.014. Epub 2015 Apr 8.

39.

A gene expression-based comparison of cell adhesion to extracellular matrix and RGD-terminated monolayers.

Sobers CJ, Wood SE, Mrksich M.

Biomaterials. 2015 Jun;52:385-94. doi: 10.1016/j.biomaterials.2015.02.045. Epub 2015 Mar 3.

40.

The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites.

AbouElfetouh A, Kuhn ML, Hu LI, Scholle MD, Sorensen DJ, Sahu AK, Becher D, Antelmann H, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ.

Microbiologyopen. 2015 Feb;4(1):66-83. doi: 10.1002/mbo3.223. Epub 2014 Nov 22.

41.

The antileishmanial activity of isoforms 6- and 8-selective histone deacetylase inhibitors.

Sodji Q, Patil V, Jain S, Kornacki JR, Mrksich M, Tekwani BL, Oyelere AK.

Bioorg Med Chem Lett. 2014 Oct 15;24(20):4826-30. doi: 10.1016/j.bmcl.2014.08.060. Epub 2014 Sep 4.

42.

Acetyltransferase p300/CBP associated Factor (PCAF) regulates crosstalk-dependent acetylation of histone H3 by distal site recognition.

Kornacki JR, Stuparu AD, Mrksich M.

ACS Chem Biol. 2015 Jan 16;10(1):157-64. doi: 10.1021/cb5004527. Epub 2014 Sep 26.

43.

Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.

Kuhn ML, Zemaitaitis B, Hu LI, Sahu A, Sorensen D, Minasov G, Lima BP, Scholle M, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ.

PLoS One. 2014 Apr 22;9(4):e94816. doi: 10.1371/journal.pone.0094816. eCollection 2014.

44.

Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia.

Brennand K, Savas JN, Kim Y, Tran N, Simone A, Hashimoto-Torii K, Beaumont KG, Kim HJ, Topol A, Ladran I, Abdelrahim M, Matikainen-Ankney B, Chao SH, Mrksich M, Rakic P, Fang G, Zhang B, Yates JR 3rd, Gage FH.

Mol Psychiatry. 2015 Mar;20(3):361-8. doi: 10.1038/mp.2014.22. Epub 2014 Apr 1.

45.

Combinatorial screening of mesenchymal stem cell adhesion and differentiation using polymer pen lithography.

Cabezas MD, Eichelsdoerfer DJ, Brown KA, Mrksich M, Mirkin CA.

Methods Cell Biol. 2014;119:261-76. doi: 10.1016/B978-0-12-416742-1.00013-5.

46.

Self-assembled monolayer facilitates epithelial-mesenchymal interactions mimicking odontogenesis.

Muni T, Mrksich M, George A.

Connect Tissue Res. 2014 Jan-Feb;55(1):26-33. doi: 10.3109/03008207.2013.867335.

PMID:
24437602
47.

Synthesis and structure-activity relationship of 3-hydroxypyridine-2-thione-based histone deacetylase inhibitors.

Sodji QH, Patil V, Kornacki JR, Mrksich M, Oyelere AK.

J Med Chem. 2013 Dec 27;56(24):9969-81. doi: 10.1021/jm401225q. Epub 2013 Dec 12.

48.

Geometric control of vimentin intermediate filaments.

Shabbir SH, Cleland MM, Goldman RD, Mrksich M.

Biomaterials. 2014 Feb;35(5):1359-66. doi: 10.1016/j.biomaterials.2013.10.008. Epub 2013 Nov 21.

49.

Profiling deacetylase activities in cell lysates with peptide arrays and SAMDI mass spectrometry.

Kuo HY, DeLuca TA, Miller WM, Mrksich M.

Anal Chem. 2013 Nov 19;85(22):10635-10642. doi: 10.1021/ac402614x. Epub 2013 Oct 11.

50.

Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice.

Peek CB, Affinati AH, Ramsey KM, Kuo HY, Yu W, Sena LA, Ilkayeva O, Marcheva B, Kobayashi Y, Omura C, Levine DC, Bacsik DJ, Gius D, Newgard CB, Goetzman E, Chandel NS, Denu JM, Mrksich M, Bass J.

Science. 2013 Nov 1;342(6158):1243417. doi: 10.1126/science.1243417. Epub 2013 Sep 19.

Supplemental Content

Loading ...
Support Center