Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 11

1.

Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway.

Benson HE, Watterson S, Sharman JL, Mpamhanga CP, Parton A, Southan C, Harmar AJ, Ghazal P.

Br J Pharmacol. 2017 Dec;174(23):4362-4382. doi: 10.1111/bph.14037. Epub 2017 Nov 26.

2.

International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands.

Davenport AP, Alexander SP, Sharman JL, Pawson AJ, Benson HE, Monaghan AE, Liew WC, Mpamhanga CP, Bonner TI, Neubig RR, Pin JP, Spedding M, Harmar AJ.

Pharmacol Rev. 2013 May 17;65(3):967-86. doi: 10.1124/pr.112.007179. Print 2013 Jul. Review.

3.

IUPHAR-DB: updated database content and new features.

Sharman JL, Benson HE, Pawson AJ, Lukito V, Mpamhanga CP, Bombail V, Davenport AP, Peters JA, Spedding M, Harmar AJ; NC-IUPHAR.

Nucleic Acids Res. 2013 Jan;41(Database issue):D1083-8. doi: 10.1093/nar/gks960. Epub 2012 Oct 18.

4.

How to use the IUPHAR receptor database to navigate pharmacological data.

Mpamhanga CP, Sharman JL, Harmar AJ; NC-IUPHAR.

Methods Mol Biol. 2012;897:15-29. doi: 10.1007/978-1-61779-909-9_2.

PMID:
22674159
5.

IUPHAR-DB: an open-access, expert-curated resource for receptor and ion channel research.

Sharman JL, Mpamhanga CP.

ACS Chem Neurosci. 2011 May 18;2(5):232-5. doi: 10.1021/cn200025w.

6.

Design, synthesis and biological evaluation of novel inhibitors of Trypanosoma brucei pteridine reductase 1.

Spinks D, Ong HB, Mpamhanga CP, Shanks EJ, Robinson DA, Collie IT, Read KD, Frearson JA, Wyatt PG, Brenk R, Fairlamb AH, Gilbert IH.

ChemMedChem. 2011 Feb 7;6(2):302-8. doi: 10.1002/cmdc.201000450. Epub 2010 Dec 29.

7.

IUPHAR-DB: new receptors and tools for easy searching and visualization of pharmacological data.

Sharman JL, Mpamhanga CP, Spedding M, Germain P, Staels B, Dacquet C, Laudet V, Harmar AJ; NC-IUPHAR.

Nucleic Acids Res. 2011 Jan;39(Database issue):D534-8. doi: 10.1093/nar/gkq1062. Epub 2010 Nov 17.

8.

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.

Frearson JA, Brand S, McElroy SP, Cleghorn LA, Smid O, Stojanovski L, Price HP, Guther ML, Torrie LS, Robinson DA, Hallyburton I, Mpamhanga CP, Brannigan JA, Wilkinson AJ, Hodgkinson M, Hui R, Qiu W, Raimi OG, van Aalten DM, Brenk R, Gilbert IH, Read KD, Fairlamb AH, Ferguson MA, Smith DF, Wyatt PG.

Nature. 2010 Apr 1;464(7289):728-32. doi: 10.1038/nature08893.

9.

One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening.

Mpamhanga CP, Spinks D, Tulloch LB, Shanks EJ, Robinson DA, Collie IT, Fairlamb AH, Wyatt PG, Frearson JA, Hunter WN, Gilbert IH, Brenk R.

J Med Chem. 2009 Jul 23;52(14):4454-65. doi: 10.1021/jm900414x.

10.

Knowledge-based interaction fingerprint scoring: a simple method for improving the effectiveness of fast scoring functions.

Mpamhanga CP, Chen B, McLay IM, Willett P.

J Chem Inf Model. 2006 Mar-Apr;46(2):686-98.

PMID:
16562999
11.

Retrospective docking study of PDE4B ligands and an analysis of the behavior of selected scoring functions.

Mpamhanga CP, Chen B, McLay IM, Ormsby DL, Lindvall MK.

J Chem Inf Model. 2005 Jul-Aug;45(4):1061-74.

PMID:
16045302

Supplemental Content

Loading ...
Support Center