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Items: 1 to 50 of 55

1.

Crellastatin A, a PARP-1 Inhibitor Discovered by Complementary Proteomic Approaches.

Morretta E, Tosco A, Festa C, Mozzicafreddo M, Monti MC, Casapullo A.

ChemMedChem. 2020 Feb 5;15(3):317-323. doi: 10.1002/cmdc.201900634. Epub 2020 Jan 8.

PMID:
31829516
2.

Draft Genome Sequence of a New Pseudomonas sp. Strain, ef1, Associated with the Psychrophilic Antarctic Ciliate Euplotes focardii.

Ramasamy KP, Telatin A, Mozzicafreddo M, Miceli C, Pucciarelli S.

Microbiol Resour Announc. 2019 Oct 10;8(41). pii: e00867-19. doi: 10.1128/MRA.00867-19.

3.

Chemical Proteomics-Guided Identification of a Novel Biological Target of the Bioactive Neolignan Magnolol.

Cassiano C, Esposito R, Tosco A, Casapullo A, Mozzicafreddo M, Tringali C, Riccio R, Monti MC.

Front Chem. 2019 Feb 8;7:53. doi: 10.3389/fchem.2019.00053. eCollection 2019.

4.

PDGFA in Cashmere Goat: A Motivation for the Hair Follicle Stem Cells to Activate.

Pazzaglia I, Mercati F, Antonini M, Capomaccio S, Cappelli K, Dall'Aglio C, La Terza A, Mozzicafreddo M, Nocelli C, Pallotti S, Pediconi D, Renieri C.

Animals (Basel). 2019 Jan 28;9(2). pii: E38. doi: 10.3390/ani9020038.

5.

Chemoproteomic fishing identifies arzanol as a positive modulator of brain glycogen phosphorylase.

Del Gaudio F, Pollastro F, Mozzicafreddo M, Riccio R, Minassi A, Monti MC.

Chem Commun (Camb). 2018 Nov 13;54(91):12863-12866. doi: 10.1039/c8cc07692h.

PMID:
30375590
6.

Plasticizers used in food-contact materials affect adipogenesis in 3T3-L1 cells.

Pomatto V, Cottone E, Cocci P, Mozzicafreddo M, Mosconi G, Nelson ER, Palermo FA, Bovolin P.

J Steroid Biochem Mol Biol. 2018 Apr;178:322-332. doi: 10.1016/j.jsbmb.2018.01.014. Epub 2018 Feb 2.

7.

Interfering with the high-affinity interaction between wheat amylase trypsin inhibitor CM3 and toll-like receptor 4: in silico and biosensor-based studies.

Cuccioloni M, Mozzicafreddo M, Bonfili L, Cecarini V, Giangrossi M, Falconi M, Saitoh SI, Eleuteri AM, Angeletti M.

Sci Rep. 2017 Oct 13;7(1):13169. doi: 10.1038/s41598-017-13709-1.

8.
9.

Proteasome as a New Target for Bio-Inspired Benzo[k,l]xanthene Lignans.

Capolupo A, Tosco A, Mozzicafreddo M, Tringali C, Cardullo N, Monti MC, Casapullo A.

Chemistry. 2017 Jun 22;23(35):8371-8374. doi: 10.1002/chem.201701095. Epub 2017 Jun 1.

PMID:
28485479
10.

Rational Engineering of a Cold-Adapted α-Amylase from the Antarctic Ciliate Euplotes focardii for Simultaneous Improvement of Thermostability and Catalytic Activity.

Yang G, Yao H, Mozzicafreddo M, Ballarini P, Pucciarelli S, Miceli C.

Appl Environ Microbiol. 2017 Jun 16;83(13). pii: e00449-17. doi: 10.1128/AEM.00449-17. Print 2017 Jul 1.

11.

Characterization of binding and quantification of human autoantibodies to PDGFRα using a biosensor-based approach.

Moroncini G, Cuccioloni M, Mozzicafreddo M, Pozniak KN, Grieco A, Paolini C, Tonnini C, Spadoni T, Svegliati S, Funaro A, Angeletti M, Gabrielli A.

Anal Biochem. 2017 Jul 1;528:26-33. doi: 10.1016/j.ab.2017.04.011. Epub 2017 Apr 24.

12.

Mangiferin blocks proliferation and induces apoptosis of breast cancer cells via suppression of the mevalonate pathway and by proteasome inhibition.

Cuccioloni M, Bonfili L, Mozzicafreddo M, Cecarini V, Scuri S, Cocchioni M, Nabissi M, Santoni G, Eleuteri AM, Angeletti M.

Food Funct. 2016 Oct 12;7(10):4299-4309.

PMID:
27722367
13.

Biomolecular proteomics discloses ATP synthase as the main target of the natural glycoside deglucoruscin.

Del Gaudio F, Festa C, Mozzicafreddo M, Vasaturo M, Casapullo A, De Marino S, Riccio R, Monti MC.

Mol Biosyst. 2016 Oct 20;12(10):3132-8. doi: 10.1039/c6mb00460a. Epub 2016 Aug 1.

PMID:
27476482
14.

In silico prediction and in vivo analysis of antiestrogenic potential of 2-isopropylthioxanthone (2-ITX) in juvenile goldfish (Carassius auratus).

Cocci P, Mozzicafreddo M, Angeletti M, Mosconi G, Palermo FA.

Ecotoxicol Environ Saf. 2016 Nov;133:202-10. doi: 10.1016/j.ecoenv.2016.07.021. Epub 2016 Jul 23.

PMID:
27454205
15.

Interaction between wheat alpha-amylase/trypsin bi-functional inhibitor and mammalian digestive enzymes: Kinetic, equilibrium and structural characterization of binding.

Cuccioloni M, Mozzicafreddo M, Ali I, Bonfili L, Cecarini V, Eleuteri AM, Angeletti M.

Food Chem. 2016 Dec 15;213:571-578. doi: 10.1016/j.foodchem.2016.07.020. Epub 2016 Jul 6.

PMID:
27451220
16.

The fine-tuning of proteolytic pathways in Alzheimer's disease.

Cecarini V, Bonfili L, Cuccioloni M, Mozzicafreddo M, Angeletti M, Keller JN, Eleuteri AM.

Cell Mol Life Sci. 2016 Sep;73(18):3433-51. doi: 10.1007/s00018-016-2238-6. Epub 2016 Apr 27. Review.

PMID:
27120560
17.

Tri-m-cresyl phosphate and PPAR/LXR interactions in seabream hepatocytes: revealed by computational modeling (docking) and transcriptional regulation of signaling pathways.

Palermo FA, Cocci P, Mozzicafreddo M, Arukwe A, Angeletti M, Aretusi G, Mosconi G.

Toxicol Res (Camb). 2015 Dec 18;5(2):471-481. doi: 10.1039/c5tx00314h. eCollection 2016 Mar 1.

18.

Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells.

Amantini C, Morelli MB, Santoni M, Soriani A, Cardinali C, Farfariello V, Eleuteri AM, Bonfili L, Mozzicafreddo M, Nabissi M, Cascinu S, Santoni G.

Oncoscience. 2015 Mar 23;2(4):395-409. eCollection 2015.

19.

Environmental pollutants directly affect the liver X receptor alpha activity: Kinetic and thermodynamic characterization of binding.

Mozzicafreddo M, Cuccioloni M, Bonfili L, Cecarini V, Palermo FA, Cocci P, Mosconi G, Capone A, Ricci I, Eleuteri AM, Angeletti M.

J Steroid Biochem Mol Biol. 2015 Aug;152:1-7. doi: 10.1016/j.jsbmb.2015.04.011. Epub 2015 Apr 11.

PMID:
25869557
20.

Effects of Diisodecyl Phthalate on PPAR:RXR-Dependent Gene Expression Pathways in Sea Bream Hepatocytes.

Cocci P, Mosconi G, Arukwe A, Mozzicafreddo M, Angeletti M, Aretusi G, Palermo FA.

Chem Res Toxicol. 2015 May 18;28(5):935-47. doi: 10.1021/tx500529x. Epub 2015 Apr 15.

PMID:
25825955
21.

Epitope Specificity Determines Pathogenicity and Detectability of Anti-Platelet-Derived Growth Factor Receptor α Autoantibodies in Systemic Sclerosis.

Moroncini G, Grieco A, Nacci G, Paolini C, Tonnini C, Pozniak KN, Cuccioloni M, Mozzicafreddo M, Svegliati S, Angeletti M, Kazlauskas A, Avvedimento EV, Funaro A, Gabrielli A.

Arthritis Rheumatol. 2015 Jul;67(7):1891-903. doi: 10.1002/art.39125.

22.

Pseudomonas fluorescens Pf-5 genome-wide mutant screen for resistance to the antimicrobial peptide alfalfa snakin-1.

Ayub ND, Fox AR, García AN, Mozzicafreddo M, Cuccioloni M, Angeletti M, Pagano E, Soto G.

FEMS Microbiol Lett. 2015 Jan;362(2):1-6. doi: 10.1093/femsle/fnu006. Epub 2014 Dec 4.

23.

Theonellasterone, a steroidal metabolite isolated from a Theonella sponge, protects peroxiredoxin-1 from oxidative stress reactions.

Margarucci L, Monti MC, Tosco A, Esposito R, Zampella A, Sepe V, Mozzicafreddo M, Riccio R, Casapullo A.

Chem Commun (Camb). 2015 Jan 31;51(9):1591-3. doi: 10.1039/c4cc09205h.

PMID:
25503482
24.

Arene-ruthenium(II) acylpyrazolonato complexes: apoptosis-promoting effects on human cancer cells.

Pettinari R, Pettinari C, Marchetti F, Skelton BW, White AH, Bonfili L, Cuccioloni M, Mozzicafreddo M, Cecarini V, Angeletti M, Nabissi M, Eleuteri AM.

J Med Chem. 2014 Jun 12;57(11):4532-42. doi: 10.1021/jm500458c. Epub 2014 May 20.

PMID:
24793593
25.

Binding of CD157 protein to fibronectin regulates cell adhesion and spreading.

Morone S, Augeri S, Cuccioloni M, Mozzicafreddo M, Angeletti M, Lo Buono N, Giacomino A, Ortolan E, Funaro A.

J Biol Chem. 2014 May 30;289(22):15588-601. doi: 10.1074/jbc.M113.535070. Epub 2014 Apr 21.

26.

Mechanistic insights on petrosaspongiolide M inhibitory effects on immunoproteasome and autophagy.

Monti MC, Margarucci L, Riccio R, Bonfili L, Mozzicafreddo M, Eleuteri AM, Casapullo A.

Biochim Biophys Acta. 2014 Apr;1844(4):713-21. doi: 10.1016/j.bbapap.2014.02.003. Epub 2014 Feb 14.

PMID:
24530967
27.

Wild type and mutant amyloid precursor proteins influence downstream effects of proteasome and autophagy inhibition.

Cecarini V, Bonfili L, Cuccioloni M, Mozzicafreddo M, Rossi G, Keller JN, Angeletti M, Eleuteri AM.

Biochim Biophys Acta. 2014 Feb;1842(2):127-34. doi: 10.1016/j.bbadis.2013.11.002. Epub 2013 Nov 8.

28.

Understanding the function of bacterial and eukaryotic thiolases II by integrating evolutionary and functional approaches.

Fox AR, Soto G, Mozzicafreddo M, Garcia AN, Cuccioloni M, Angeletti M, Salerno JC, Ayub ND.

Gene. 2014 Jan 1;533(1):5-10. doi: 10.1016/j.gene.2013.09.096. Epub 2013 Oct 11. Review.

PMID:
24120621
29.

Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells.

Santoni M, Amantini C, Morelli MB, Liberati S, Farfariello V, Nabissi M, Bonfili L, Eleuteri AM, Mozzicafreddo M, Burattini L, Berardi R, Cascinu S, Santoni G.

Br J Cancer. 2013 Aug 20;109(4):1040-50. doi: 10.1038/bjc.2013.420. Epub 2013 Jul 25.

30.

Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor.

Margarucci L, Monti MC, Cassiano C, Mozzicafreddo M, Angeletti M, Riccio R, Tosco A, Casapullo A.

Chem Commun (Camb). 2013 Jul 4;49(52):5844-6. doi: 10.1039/c3cc41858h. Epub 2013 May 24.

PMID:
23703283
31.

Engineering Pseudomonas protegens Pf-5 for nitrogen fixation and its application to improve plant growth under nitrogen-deficient conditions.

Setten L, Soto G, Mozzicafreddo M, Fox AR, Lisi C, Cuccioloni M, Angeletti M, Pagano E, Díaz-Paleo A, Ayub ND.

PLoS One. 2013 May 13;8(5):e63666. doi: 10.1371/journal.pone.0063666. Print 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/279fe0d7-d9b1-4d05-a45a-5ff00b4606b7.

32.

Ghrelin induces apoptosis in colon adenocarcinoma cells via proteasome inhibition and autophagy induction.

Bonfili L, Cuccioloni M, Cecarini V, Mozzicafreddo M, Palermo FA, Cocci P, Angeletti M, Eleuteri AM.

Apoptosis. 2013 Oct;18(10):1188-200. doi: 10.1007/s10495-013-0856-0.

PMID:
23632965
33.

Arene-Ru(II) complexes of curcumin exert antitumor activity via proteasome inhibition and apoptosis induction.

Bonfili L, Pettinari R, Cuccioloni M, Cecarini V, Mozzicafreddo M, Angeletti M, Lupidi G, Marchetti F, Pettinari C, Eleuteri AM.

ChemMedChem. 2012 Nov;7(11):2010-20. doi: 10.1002/cmdc.201200341. Epub 2012 Sep 20.

PMID:
22997162
34.

Crosstalk between the ubiquitin-proteasome system and autophagy in a human cellular model of Alzheimer's disease.

Cecarini V, Bonfili L, Cuccioloni M, Mozzicafreddo M, Rossi G, Buizza L, Uberti D, Angeletti M, Eleuteri AM.

Biochim Biophys Acta. 2012 Nov;1822(11):1741-51. doi: 10.1016/j.bbadis.2012.07.015. Epub 2012 Jul 31.

35.

Hydroxybutyrate prevents protein aggregation in the halotolerant bacterium Pseudomonas sp. CT13 under abiotic stress.

Soto G, Setten L, Lisi C, Maurelis C, Mozzicafreddo M, Cuccioloni M, Angeletti M, Ayub ND.

Extremophiles. 2012 May;16(3):455-62. doi: 10.1007/s00792-012-0445-0. Epub 2012 Apr 13.

PMID:
22527039
36.

Sanguisorba minor extract suppresses plasmin-mediated mechanisms of cancer cell migration.

Cuccioloni M, Bonfili L, Mozzicafreddo M, Cecarini V, Eleuteri AM, Angeletti M.

Biochim Biophys Acta. 2012 Jul;1820(7):1027-34. doi: 10.1016/j.bbagen.2012.02.002. Epub 2012 Feb 14.

PMID:
22348918
37.

Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation.

Soto G, Stritzler M, Lisi C, Alleva K, Pagano ME, Ardila F, Mozzicafreddo M, Cuccioloni M, Angeletti M, Ayub ND.

J Exp Bot. 2011 Nov;62(15):5699-711. doi: 10.1093/jxb/err287. Epub 2011 Sep 9.

PMID:
21908473
38.

Epigallocatechin-3-gallate potently inhibits the in vitro activity of hydroxy-3-methyl-glutaryl-CoA reductase.

Cuccioloni M, Mozzicafreddo M, Spina M, Tran CN, Falconi M, Eleuteri AM, Angeletti M.

J Lipid Res. 2011 May;52(5):897-907. doi: 10.1194/jlr.M011817. Epub 2011 Feb 25.

39.

Identification of an EGCG oxidation derivative with proteasome modulatory activity.

Bonfili L, Cuccioloni M, Mozzicafreddo M, Cecarini V, Angeletti M, Eleuteri AM.

Biochimie. 2011 May;93(5):931-40. doi: 10.1016/j.biochi.2011.02.003. Epub 2011 Feb 24.

PMID:
21354258
40.

Targeting proteasomes with natural occurring compounds in cancer treatment.

Cecarini V, Cuccioloni M, Mozzicafreddo M, Bonfili L, Angeletti M, Eleuteri AM.

Curr Cancer Drug Targets. 2011 Mar;11(3):307-24. Review.

PMID:
21265733
41.

Influence of relative humidity on the interaction between different aryl propionic acid derivatives and poly(vinylpyrrolydone) K30: evaluation of the effect on drug bioavailability.

Malaj L, Censi R, Mozzicafreddo M, Pellegrino L, Angeletti M, Gobetto R, Di Martino P.

Int J Pharm. 2010 Oct 15;398(1-2):61-72. doi: 10.1016/j.ijpharm.2010.07.024. Epub 2010 Jul 22.

PMID:
20655373
42.

Rapid reverse phase-HPLC assay of HMG-CoA reductase activity.

Mozzicafreddo M, Cuccioloni M, Eleuteri AM, Angeletti M.

J Lipid Res. 2010 Aug;51(8):2460-3. doi: 10.1194/jlr.D006155. Epub 2010 Apr 24.

43.

Effects of thymoquinone on isolated and cellular proteasomes.

Cecarini V, Quassinti L, Di Blasio A, Bonfili L, Bramucci M, Lupidi G, Cuccioloni M, Mozzicafreddo M, Angeletti M, Eleuteri AM.

FEBS J. 2010 May;277(9):2128-41. doi: 10.1111/j.1742-4658.2010.07629.x.

44.

The relationship between the 20S proteasomes and prion-mediated neurodegenerations: potential therapeutic opportunities.

Cecarini V, Bonfili L, Cuccioloni M, Mozzicafreddo M, Angeletti M, Eleuteri AM.

Apoptosis. 2010 Nov;15(11):1322-35. doi: 10.1007/s10495-010-0480-1. Review.

PMID:
20213200
45.

Differences in the interaction between aryl propionic acid derivatives and poly(vinylpyrrolidone) K30: A multi-methodological approach.

Gashi Z, Censi R, Malaj L, Gobetto R, Mozzicafreddo M, Angeletti M, Masic A, Di Martino P.

J Pharm Sci. 2009 Nov;98(11):4216-28. doi: 10.1002/jps.21734.

PMID:
19645003
46.

Biosensor-based screening method for the detection of aflatoxins B1-G1.

Cuccioloni M, Mozzicafreddo M, Barocci S, Ciuti F, Pecorelli I, Eleuteri AM, Spina M, Fioretti E, Angeletti M.

Anal Chem. 2008 Dec 1;80(23):9250-6. doi: 10.1021/ac801612w.

PMID:
19551989
47.

Natural occurring polyphenols as template for drug design. Focus on serine proteases.

Cuccioloni M, Mozzicafreddo M, Bonfili L, Cecarini V, Eleuteri AM, Angeletti M.

Chem Biol Drug Des. 2009 Jul;74(1):1-15. doi: 10.1111/j.1747-0285.2009.00836.x. Review.

PMID:
19519739
48.

Aflatoxin B1 misregulates the activity of serine proteases: possible implications in the toxicity of some mycotoxin.

Cuccioloni M, Mozzicafreddo M, Barocci S, Ciuti F, Re L, Eleuteri AM, Angeletti M.

Toxicol In Vitro. 2009 Apr;23(3):393-9.

PMID:
19444922
49.

Homology modeling and docking analysis of the interaction between polyphenols and mammalian 20S proteasomes.

Mozzicafreddo M, Cuccioloni M, Cecarini V, Eleuteri AM, Angeletti M.

J Chem Inf Model. 2009 Feb;49(2):401-9. doi: 10.1021/ci800235m.

PMID:
19434841
50.

Pomegranate fruit components modulate human thrombin.

Cuccioloni M, Mozzicafreddo M, Sparapani L, Spina M, Eleuteri AM, Fioretti E, Angeletti M.

Fitoterapia. 2009 Jul;80(5):301-5. doi: 10.1016/j.fitote.2009.03.009. Epub 2009 Apr 7.

PMID:
19358882

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