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Items: 24

1.

Interactions of multitargeted kinase inhibitors and nucleoside drugs: Achilles heel of combination therapy?

Damaraju VL, Kuzma M, Mowles D, Cass CE, Sawyer MB.

Mol Cancer Ther. 2015 Jan;14(1):236-45. doi: 10.1158/1535-7163.MCT-14-0337. Epub 2014 Dec 17.

2.

Comparative in vitro evaluation of transportability and toxicity of capecitabine and its metabolites in cells derived from normal human kidney and renal cancers.

Damaraju VL, Mowles D, Wilson M, Kuzma M, Cass CE, Sawyer MB.

Biochem Cell Biol. 2013 Dec;91(6):419-27. doi: 10.1139/bcb-2013-0041. Epub 2013 Jun 17.

PMID:
24219283
3.

Erlotinib, gefitinib, and vandetanib inhibit human nucleoside transporters and protect cancer cells from gemcitabine cytotoxicity.

Damaraju VL, Scriver T, Mowles D, Kuzma M, Ryan AJ, Cass CE, Sawyer MB.

Clin Cancer Res. 2014 Jan 1;20(1):176-86. doi: 10.1158/1078-0432.CCR-13-2293. Epub 2013 Oct 29.

4.

Cellular influx, efflux, and anabolism of 3-carboranyl thymidine analogs: potential boron delivery agents for neutron capture therapy.

Sjuvarsson E, Damaraju VL, Mowles D, Sawyer MB, Tiwari R, Agarwal HK, Khalil A, Hasabelnaby S, Goudah A, Nakkula RJ, Barth RF, Cass CE, Eriksson S, Tjarks W.

J Pharmacol Exp Ther. 2013 Nov;347(2):388-97. doi: 10.1124/jpet.113.207464. Epub 2013 Sep 4.

5.

Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine.

Damaraju VL, Mowles D, Yao S, Ng A, Young JD, Cass CE, Tong Z.

Nucleosides Nucleotides Nucleic Acids. 2012;31(3):236-55. doi: 10.1080/15257770.2011.652330.

PMID:
22356238
6.

Influence of sugar ring conformation on the transportability of nucleosides by human nucleoside transporters.

Damaraju VL, Mowles D, Smith KM, Yao SY, Young JD, Marquez VE, Cass CE.

Chembiochem. 2011 Dec 16;12(18):2774-8. doi: 10.1002/cbic.201100567. Epub 2011 Nov 4.

PMID:
22052809
7.

Nucleoside transporter gene expression in wild-type and mENT1 knockout mice.

Graham K, Yao S, Johnson L, Mowles D, Ng A, Wilkinson J, Young JD, Cass CE.

Biochem Cell Biol. 2011 Apr;89(2):236-45. doi: 10.1139/o10-152.

PMID:
21455274
8.

Interaction of fused-pyrimidine nucleoside analogs with human concentrative nucleoside transporters: High-affinity inhibitors of human concentrative nucleoside transporter 1.

Damaraju VL, Smith KM, Mowles D, Nowak I, Karpinski E, Young JD, Robins MJ, Cass CE.

Biochem Pharmacol. 2011 Jan 1;81(1):82-90. doi: 10.1016/j.bcp.2010.09.009. Epub 2010 Sep 18.

PMID:
20854794
10.

Cytotoxic activity of gemcitabine in cultured cell lines derived from histologically different types of bladder cancer: role of thymidine kinase 2.

Damaraju S, Damaraju VL, Mowles D, Sawyer MB, Damaraju S, Cass CE.

Biochem Pharmacol. 2010 Jan 1;79(1):21-9. doi: 10.1016/j.bcp.2009.07.018. Epub 2009 Aug 4.

PMID:
19660438
11.

Transepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: roles of nucleoside transporters hENT1, hENT2, and hCNT3.

Elwi AN, Damaraju VL, Kuzma ML, Mowles DA, Baldwin SA, Young JD, Sawyer MB, Cass CE.

Am J Physiol Renal Physiol. 2009 Jun;296(6):F1439-51. doi: 10.1152/ajprenal.90411.2008. Epub 2009 Mar 18.

12.

Two distinct molecular mechanisms underlying cytarabine resistance in human leukemic cells.

Cai J, Damaraju VL, Groulx N, Mowles D, Peng Y, Robins MJ, Cass CE, Gros P.

Cancer Res. 2008 Apr 1;68(7):2349-57. doi: 10.1158/0008-5472.CAN-07-5528.

13.

Cytotoxic activities of nucleoside and nucleobase analog drugs in malignant mesothelioma: characterization of a novel nucleobase transport activity.

Damaraju D, Damaraju VL, Brun M, Mowles D, Kuzma M, Berendt RC, Sawyer MB, Cass CE.

Biochem Pharmacol. 2008 May 15;75(10):1901-11. doi: 10.1016/j.bcp.2008.02.006. Epub 2008 Feb 16.

PMID:
18371936
14.

The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine.

Clarke ML, Damaraju VL, Zhang J, Mowles D, Tackaberry T, Lang T, Smith KM, Young JD, Tomkinson B, Cass CE.

Mol Pharmacol. 2006 Jul;70(1):303-10. Epub 2006 Apr 14.

PMID:
16617163
15.

A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems.

King KM, Damaraju VL, Vickers MF, Yao SY, Lang T, Tackaberry TE, Mowles DA, Ng AM, Young JD, Cass CE.

Mol Pharmacol. 2006 Jan;69(1):346-53. Epub 2005 Oct 18.

PMID:
16234483
16.

Role of human nucleoside transporters in the cellular uptake of two inhibitors of IMP dehydrogenase, tiazofurin and benzamide riboside.

Damaraju VL, Visser F, Zhang J, Mowles D, Ng AM, Young JD, Jayaram HN, Cass CE.

Mol Pharmacol. 2005 Jan;67(1):273-9. Epub 2004 Oct 14.

PMID:
15486050
17.

Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.

Gourdeau H, Clarke ML, Ouellet F, Mowles D, Selner M, Richard A, Lee N, Mackey JR, Young JD, Jolivet J, Lafrenière RG, Cass CE.

Cancer Res. 2001 Oct 1;61(19):7217-24.

18.

Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).

Ritzel MW, Ng AM, Yao SY, Graham K, Loewen SK, Smith KM, Ritzel RG, Mowles DA, Carpenter P, Chen XZ, Karpinski E, Hyde RJ, Baldwin SA, Cass CE, Young JD.

J Biol Chem. 2001 Jan 26;276(4):2914-27. Epub 2000 Oct 13.

19.

Differential transport of cytosine-containing nucleosides by recombinant human concentrative nucleoside transporter protein hCNT1.

Graham KA, Leithoff J, Coe IR, Mowles D, Mackey JR, Young JD, Cass CE.

Nucleosides Nucleotides Nucleic Acids. 2000 Jan-Feb;19(1-2):415-34.

PMID:
10772724
20.

Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines.

Mackey JR, Mani RS, Selner M, Mowles D, Young JD, Belt JA, Crawford CR, Cass CE.

Cancer Res. 1998 Oct 1;58(19):4349-57.

22.

Stability of Liposyn II fat emulsion in total nutrient admixtures.

Sayeed FA, Johnson HW, Sukumaran KB, Raihle JA, Mowles DL, Stelmach HA, Majors KR.

Am J Hosp Pharm. 1986 May;43(5):1230-5.

PMID:
3087165
23.

The DNA content of human plasma cells.

Brox L, Mowles D, Pollock B, Belch A.

Cancer. 1981 May 15;47(10):2433-6.

PMID:
6168350
24.

Inhibition by arabinosylcytosine of DNA synthesis in bone marrows of relapsed AML patients.

Brox L, Mowles D, Belch A.

Eur J Cancer. 1979 Oct;15(10):1263-8. No abstract available.

PMID:
293261

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