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Items: 33

1.

Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.

Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gómez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, González-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O.

Nature. 2019 May;569(7755):236-240. doi: 10.1038/s41586-019-1167-6. Epub 2019 May 1.

PMID:
31043745
2.

Myeloid-Specific Deletion of Peptidylarginine Deiminase 4 Mitigates Atherosclerosis.

Liu Y, Carmona-Rivera C, Moore E, Seto NL, Knight JS, Pryor M, Yang ZH, Hemmers S, Remaley AT, Mowen KA, Kaplan MJ.

Front Immunol. 2018 Jul 26;9:1680. doi: 10.3389/fimmu.2018.01680. eCollection 2018.

3.

Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis.

Leppkes M, Maueröder C, Hirth S, Nowecki S, Günther C, Billmeier U, Paulus S, Biermann M, Munoz LE, Hoffmann M, Wildner D, Croxford AL, Waisman A, Mowen K, Jenne DE, Krenn V, Mayerle J, Lerch MM, Schett G, Wirtz S, Neurath MF, Herrmann M, Becker C.

Nat Commun. 2016 Mar 11;7:10973. doi: 10.1038/ncomms10973.

4.

Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia.

Cheung N, Fung TK, Zeisig BB, Holmes K, Rane JK, Mowen KA, Finn MG, Lenhard B, Chan LC, So CW.

Cancer Cell. 2016 Jan 11;29(1):32-48. doi: 10.1016/j.ccell.2015.12.007.

5.

Neutrophil Extracellular Traps Promote the Development and Progression of Liver Metastases after Surgical Stress.

Tohme S, Yazdani HO, Al-Khafaji AB, Chidi AP, Loughran P, Mowen K, Wang Y, Simmons RL, Huang H, Tsung A.

Cancer Res. 2016 Mar 15;76(6):1367-80. doi: 10.1158/0008-5472.CAN-15-1591. Epub 2016 Jan 12.

6.

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature.

Kolaczkowska E, Jenne CN, Surewaard BG, Thanabalasuriar A, Lee WY, Sanz MJ, Mowen K, Opdenakker G, Kubes P.

Nat Commun. 2015 Mar 26;6:6673. doi: 10.1038/ncomms7673.

7.

Unconventional post-translational modifications in immunological signaling.

Mowen KA, David M.

Nat Immunol. 2014 Jun;15(6):512-20. doi: 10.1038/ni.2873. Review.

PMID:
24840982
8.

Citrullination regulates pluripotency and histone H1 binding to chromatin.

Christophorou MA, Castelo-Branco G, Halley-Stott RP, Oliveira CS, Loos R, Radzisheuskaya A, Mowen KA, Bertone P, Silva JC, Zernicka-Goetz M, Nielsen ML, Gurdon JB, Kouzarides T.

Nature. 2014 Mar 6;507(7490):104-8. doi: 10.1038/nature12942. Epub 2014 Jan 26.

9.

Dendritic epidermal T cells regulate skin antimicrobial barrier function.

MacLeod AS, Hemmers S, Garijo O, Chabod M, Mowen K, Witherden DA, Havran WL.

J Clin Invest. 2013 Oct;123(10):4364-74. doi: 10.1172/JCI70064. Epub 2013 Sep 24.

10.

Automethylation of protein arginine methyltransferase 8 (PRMT8) regulates activity by impeding S-adenosylmethionine sensitivity.

Dillon MB, Rust HL, Thompson PR, Mowen KA.

J Biol Chem. 2013 Sep 27;288(39):27872-80. doi: 10.1074/jbc.M113.491092. Epub 2013 Aug 14.

11.

Activation of PAD4 in NET formation.

Rohrbach AS, Slade DJ, Thompson PR, Mowen KA.

Front Immunol. 2012 Nov 29;3:360. doi: 10.3389/fimmu.2012.00360. eCollection 2012.

12.

Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris.

Fernandez-Castaneda A, Arandjelovic S, Stiles TL, Schlobach RK, Mowen KA, Gonias SL, Gaultier A.

J Biol Chem. 2013 Feb 15;288(7):4538-48. doi: 10.1074/jbc.M112.384693. Epub 2012 Dec 21.

13.

ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor.

Arandjelovic S, McKenney KR, Leming SS, Mowen KA.

J Immunol. 2012 Oct 15;189(8):4112-22. doi: 10.4049/jimmunol.1201098. Epub 2012 Sep 14.

14.

PAD4 is not essential for disease in the K/BxN murine autoantibody-mediated model of arthritis.

Rohrbach AS, Hemmers S, Arandjelovic S, Corr M, Mowen KA.

Arthritis Res Ther. 2012 May 2;14(3):R104. doi: 10.1186/ar3829.

15.

Novel inhibitors for PRMT1 discovered by high-throughput screening using activity-based fluorescence polarization.

Dillon MB, Bachovchin DA, Brown SJ, Finn MG, Rosen H, Cravatt BF, Mowen KA.

ACS Chem Biol. 2012 Jul 20;7(7):1198-204. doi: 10.1021/cb300024c. Epub 2012 Apr 20.

16.

PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection.

Hemmers S, Teijaro JR, Arandjelovic S, Mowen KA.

PLoS One. 2011;6(7):e22043. doi: 10.1371/journal.pone.0022043. Epub 2011 Jul 11.

17.

Quantitative reactivity profiling predicts functional cysteines in proteomes.

Weerapana E, Wang C, Simon GM, Richter F, Khare S, Dillon MB, Bachovchin DA, Mowen K, Baker D, Cravatt BF.

Nature. 2010 Dec 9;468(7325):790-5. doi: 10.1038/nature09472. Epub 2010 Nov 17.

18.

Mast cell function is not altered by Coronin-1A deficiency.

Arandjelovic S, Wickramarachchi D, Hemmers S, Leming SS, Kono DH, Mowen KA.

J Leukoc Biol. 2010 Oct;88(4):737-45. doi: 10.1189/jlb.0310131. Epub 2010 Jul 19.

19.

Effects of a novel arginine methyltransferase inhibitor on T-helper cell cytokine production.

Bonham K, Hemmers S, Lim YH, Hill DM, Finn MG, Mowen KA.

FEBS J. 2010 May;277(9):2096-108. doi: 10.1111/j.1742-4658.2010.07623.x. Epub 2010 Mar 22.

20.

NIP45 controls the magnitude of the type 2 T helper cell response.

Fathman JW, Gurish MF, Hemmers S, Bonham K, Friend DS, Grusby MJ, Glimcher LH, Mowen KA.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3663-8. doi: 10.1073/pnas.0914700107. Epub 2010 Feb 4.

21.

T(H)2 bias: Mina tips the balance.

Hemmers S, Mowen KA.

Nat Immunol. 2009 Aug;10(8):806-8. doi: 10.1038/ni0809-806. No abstract available.

PMID:
19621039
22.

Signaling pathways in Th2 development.

Mowen KA, Glimcher LH.

Immunol Rev. 2004 Dec;202:203-22. Review.

PMID:
15546395
23.

Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes.

Mowen KA, Schurter BT, Fathman JW, David M, Glimcher LH.

Mol Cell. 2004 Aug 27;15(4):559-71.

24.

Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression.

Rengarajan J, Mowen KA, McBride KD, Smith ED, Singh H, Glimcher LH.

J Exp Med. 2002 Apr 15;195(8):1003-12.

25.
26.

Regulation of STAT protein synthesis by c-Cbl.

Blesofsky WA, Mowen K, Arduini RM, Baker DP, Murphy MA, Bowtell DD, David M.

Oncogene. 2001 Nov 1;20(50):7326-33.

27.

Cytokine activation of transcription.

Mowen KA, David M.

Genet Eng (N Y). 2001;23:35-44. Review. No abstract available.

PMID:
11570105
28.

Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45).

Lieberson R, Mowen KA, McBride KD, Leautaud V, Zhang X, Suh WK, Wu L, Glimcher LH.

J Exp Med. 2001 Jul 2;194(1):89-98.

29.

Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription.

Mowen KA, Tang J, Zhu W, Schurter BT, Shuai K, Herschman HR, David M.

Cell. 2001 Mar 9;104(5):731-41.

30.

Regulation of STAT1 nuclear export by Jak1.

Mowen K, David M.

Mol Cell Biol. 2000 Oct;20(19):7273-81.

31.
32.

Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein.

Huggenvik JI, Michelson RJ, Collard MW, Ziemba AJ, Gurley P, Mowen KA.

Mol Endocrinol. 1998 Oct;12(10):1619-39.

PMID:
9773984
33.

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