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Items: 48

1.

Human defects in STAT3 promote oral mucosal fungal and bacterial dysbiosis.

Abusleme L, Diaz PI, Freeman AF, Greenwell-Wild T, Brenchley L, Desai JV, Ng WI, Holland SM, Lionakis MS, Segre JA, Kong HH, Moutsopoulos NM.

JCI Insight. 2018 Sep 6;3(17). pii: 122061. doi: 10.1172/jci.insight.122061. [Epub ahead of print]

2.

Transcriptional signature primes human oral mucosa for rapid wound healing.

Iglesias-Bartolome R, Uchiyama A, Molinolo AA, Abusleme L, Brooks SR, Callejas-Valera JL, Edwards D, Doci C, Asselin-Labat ML, Onaitis MW, Moutsopoulos NM, Gutkind JS, Morasso MI.

Sci Transl Med. 2018 Jul 25;10(451). pii: eaap8798. doi: 10.1126/scitranslmed.aap8798.

PMID:
30045979
3.

Response to comment on "Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis".

Konig MF, Giles JT, Teles RP, Moutsopoulos NM, Andrade F.

Sci Transl Med. 2018 Mar 21;10(433). pii: eaao3031. doi: 10.1126/scitranslmed.aao3031.

PMID:
29563318
4.

The oral mucosa: A barrier site participating in tissue-specific and systemic immunity.

Moutsopoulos NM, Moutsopoulos HM.

Oral Dis. 2018 Mar;24(1-2):22-25. doi: 10.1111/odi.12729.

PMID:
29480644
5.

Oral Microbiome Characterization in Murine Models.

Abusleme L, Hong BY, Hoare A, Konkel JE, Diaz PI, Moutsopoulos NM.

Bio Protoc. 2017 Dec 20;7(24). pii: e2655. doi: 10.21769/BioProtoc.2655.

6.

Unique Tailoring of Th17 at the Gingival Oral Mucosal Barrier.

Konkel JE, Moutsopoulos NM.

J Dent Res. 2018 Feb;97(2):128-131. doi: 10.1177/0022034517736030. Epub 2017 Oct 13.

PMID:
29028424
7.

Tissue-Specific Immunity at the Oral Mucosal Barrier.

Moutsopoulos NM, Konkel JE.

Trends Immunol. 2018 Apr;39(4):276-287. doi: 10.1016/j.it.2017.08.005. Epub 2017 Sep 8. Review.

8.

Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1.

Moutsopoulos NM, Zerbe CS, Wild T, Dutzan N, Brenchley L, DiPasquale G, Uzel G, Axelrod KC, Lisco A, Notarangelo LD, Hajishengallis G, Notarangelo LD, Holland SM.

N Engl J Med. 2017 Mar 23;376(12):1141-1146. doi: 10.1056/NEJMoa1612197.

9.

Haploidentical Related Donor Hematopoietic Stem Cell Transplantation for Dedicator-of-Cytokinesis 8 Deficiency Using Post-Transplantation Cyclophosphamide.

Shah NN, Freeman AF, Su H, Cole K, Parta M, Moutsopoulos NM, Baris S, Karakoc-Aydiner E, Hughes TE, Kong HH, Holland SM, Hickstein DD.

Biol Blood Marrow Transplant. 2017 Jun;23(6):980-990. doi: 10.1016/j.bbmt.2017.03.016. Epub 2017 Mar 10.

10.

On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier.

Dutzan N, Abusleme L, Bridgeman H, Greenwell-Wild T, Zangerle-Murray T, Fife ME, Bouladoux N, Linley H, Brenchley L, Wemyss K, Calderon G, Hong BY, Break TJ, Bowdish DME, Lionakis MS, Jones SA, Trinchieri G, Diaz PI, Belkaid Y, Konkel JE, Moutsopoulos NM.

Immunity. 2017 Jan 17;46(1):133-147. doi: 10.1016/j.immuni.2016.12.010. Epub 2017 Jan 10.

11.

Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis.

Konig MF, Abusleme L, Reinholdt J, Palmer RJ, Teles RP, Sampson K, Rosen A, Nigrovic PA, Sokolove J, Giles JT, Moutsopoulos NM, Andrade F.

Sci Transl Med. 2016 Dec 14;8(369):369ra176.

12.

IL-17: overview and role in oral immunity and microbiome.

Abusleme L, Moutsopoulos NM.

Oral Dis. 2017 Oct;23(7):854-865. doi: 10.1111/odi.12598. Epub 2016 Dec 27. Review.

PMID:
27763707
13.

Redefined clinical features and diagnostic criteria in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.

Ferre EM, Rose SR, Rosenzweig SD, Burbelo PD, Romito KR, Niemela JE, Rosen LB, Break TJ, Gu W, Hunsberger S, Browne SK, Hsu AP, Rampertaap S, Swamydas M, Collar AL, Kong HH, Lee CR, Chascsa D, Simcox T, Pham A, Bondici A, Natarajan M, Monsale J, Kleiner DE, Quezado M, Alevizos I, Moutsopoulos NM, Yockey L, Frein C, Soldatos A, Calvo KR, Adjemian J, Similuk MN, Lang DM, Stone KD, Uzel G, Kopp JB, Bishop RJ, Holland SM, Olivier KN, Fleisher TA, Heller T, Winer KK, Lionakis MS.

JCI Insight. 2016 Aug 18;1(13). pii: e88782.

14.

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

Falcone EL, Abusleme L, Swamydas M, Lionakis MS, Ding L, Hsu AP, Zelazny AM, Moutsopoulos NM, Kuhns DB, Deming C, Quiñones M, Segre JA, Bryant CE, Holland SM.

Microbiome. 2016 Apr 5;4:13. doi: 10.1186/s40168-016-0159-0.

15.

Isolation, Characterization and Functional Examination of the Gingival Immune Cell Network.

Dutzan N, Abusleme L, Konkel JE, Moutsopoulos NM.

J Vis Exp. 2016 Feb 16;(108):53736. doi: 10.3791/53736.

16.

Immune and regulatory functions of neutrophils in inflammatory bone loss.

Hajishengallis G, Moutsopoulos NM, Hajishengallis E, Chavakis T.

Semin Immunol. 2016 Apr;28(2):146-58. doi: 10.1016/j.smim.2016.02.002. Epub 2016 Feb 28. Review.

17.

Characterization of the human immune cell network at the gingival barrier.

Dutzan N, Konkel JE, Greenwell-Wild T, Moutsopoulos NM.

Mucosal Immunol. 2016 Sep;9(5):1163-1172. doi: 10.1038/mi.2015.136. Epub 2016 Jan 6.

18.

Role of bacteria in leukocyte adhesion deficiency-associated periodontitis.

Hajishengallis G, Moutsopoulos NM.

Microb Pathog. 2016 May;94:21-6. doi: 10.1016/j.micpath.2015.09.003. Epub 2015 Sep 14. Review.

19.

Inborn errors in immunity: unique natural models to dissect oral immunity.

Moutsopoulos NM, Lionakis MS, Hajishengallis G.

J Dent Res. 2015 Jun;94(6):753-8. doi: 10.1177/0022034515583533. Epub 2015 Apr 21. Review.

20.

Subgingival microbial communities in Leukocyte Adhesion Deficiency and their relationship with local immunopathology.

Moutsopoulos NM, Chalmers NI, Barb JJ, Abusleme L, Greenwell-Wild T, Dutzan N, Paster BJ, Munson PJ, Fine DH, Uzel G, Holland SM.

PLoS Pathog. 2015 Mar 5;11(3):e1004698. doi: 10.1371/journal.ppat.1004698. eCollection 2015 Mar. Erratum in: PLoS Pathog. 2015 Apr;11(4):e1004860.

21.

A 17-year old patient with DOCK8 deficiency, severe oral HSV-1 and aggressive periodontitis - a case of virally induced periodontitis?

Betts K, Abusleme L, Freeman AF, Sarmadi M, Fahle G, Pittaluga S, Cuellar-Rodriguez J, Hickstein D, Holland SM, Su H, Moutsopoulos NM.

J Clin Virol. 2015 Feb;63:46-50. doi: 10.1016/j.jcv.2014.12.003. Epub 2014 Dec 5.

22.

Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors.

Sales KU, Friis S, Abusleme L, Moutsopoulos NM, Bugge TH.

Oncogene. 2015 Aug 27;34(35):4664-72. doi: 10.1038/onc.2014.391. Epub 2014 Dec 8.

23.

Etiology of leukocyte adhesion deficiency-associated periodontitis revisited: not a raging infection but a raging inflammatory response.

Hajishengallis G, Moutsopoulos NM.

Expert Rev Clin Immunol. 2014 Aug;10(8):973-5. doi: 10.1586/1744666X.2014.929944. Epub 2014 Jun 14. Review.

24.

Defective neutrophil recruitment in leukocyte adhesion deficiency type I disease causes local IL-17-driven inflammatory bone loss.

Moutsopoulos NM, Konkel J, Sarmadi M, Eskan MA, Wild T, Dutzan N, Abusleme L, Zenobia C, Hosur KB, Abe T, Uzel G, Chen W, Chavakis T, Holland SM, Hajishengallis G.

Sci Transl Med. 2014 Mar 26;6(229):229ra40. doi: 10.1126/scitranslmed.3007696.

25.

A link between interferon and augmented plasmin generation in exocrine gland damage in Sjögren's syndrome.

Gliozzi M, Greenwell-Wild T, Jin W, Moutsopoulos NM, Kapsogeorgou E, Moutsopoulos HM, Wahl SM.

J Autoimmun. 2013 Feb;40:122-33. doi: 10.1016/j.jaut.2012.09.003. Epub 2012 Oct 27.

26.

Oral manifestations of systemic autoimmune and inflammatory diseases: diagnosis and clinical management.

Mays JW, Sarmadi M, Moutsopoulos NM.

J Evid Based Dent Pract. 2012 Sep;12(3 Suppl):265-82. doi: 10.1016/S1532-3382(12)70051-9. Review.

PMID:
23040353
27.

Porphyromonas gingivalis promotes Th17 inducing pathways in chronic periodontitis.

Moutsopoulos NM, Kling HM, Angelov N, Jin W, Palmer RJ, Nares S, Osorio M, Wahl SM.

J Autoimmun. 2012 Dec;39(4):294-303. doi: 10.1016/j.jaut.2012.03.003. Epub 2012 May 3.

28.

Chitinases in the salivary glands and circulation of patients with Sjögren's syndrome: macrophage harbingers of disease severity.

Greenwell-Wild T, Moutsopoulos NM, Gliozzi M, Kapsogeorgou E, Rangel Z, Munson PJ, Moutsopoulos HM, Wahl SM.

Arthritis Rheum. 2011 Oct;63(10):3103-15. doi: 10.1002/art.30465.

29.

Systemic and local interleukin-17 and linked cytokines associated with Sjögren's syndrome immunopathogenesis.

Katsifis GE, Rekka S, Moutsopoulos NM, Pillemer S, Wahl SM.

Am J Pathol. 2009 Sep;175(3):1167-77. doi: 10.2353/ajpath.2009.090319. Epub 2009 Aug 21.

30.

Rapid myeloid cell transcriptional and proteomic responses to periodontopathogenic Porphyromonas gingivalis.

Nares S, Moutsopoulos NM, Angelov N, Rangel ZG, Munson PJ, Sinha N, Wahl SM.

Am J Pathol. 2009 Apr;174(4):1400-14. doi: 10.2353/ajpath.2009.080677. Epub 2009 Mar 5.

31.

Foxp3+ T-regulatory cells in Sjogren's syndrome: correlation with the grade of the autoimmune lesion and certain adverse prognostic factors.

Christodoulou MI, Kapsogeorgou EK, Moutsopoulos NM, Moutsopoulos HM.

Am J Pathol. 2008 Nov;173(5):1389-96. doi: 10.2353/ajpath.2008.080246. Epub 2008 Sep 25.

32.

TGF-beta and tumors--an ill-fated alliance.

Moutsopoulos NM, Wen J, Wahl SM.

Curr Opin Immunol. 2008 Apr;20(2):234-40. doi: 10.1016/j.coi.2008.04.003. Epub 2008 May 15. Review.

33.

Lack of efficacy of etanercept in Sjögren syndrome correlates with failed suppression of tumour necrosis factor alpha and systemic immune activation.

Moutsopoulos NM, Katsifis GE, Angelov N, Leakan RA, Sankar V, Pillemer S, Wahl SM.

Ann Rheum Dis. 2008 Oct;67(10):1437-43. doi: 10.1136/ard.2007.077891. Epub 2008 Jan 15.

PMID:
18198195
34.

Augmented interferon-alpha pathway activation in patients with Sjögren's syndrome treated with etanercept.

Mavragani CP, Niewold TB, Moutsopoulos NM, Pillemer SR, Wahl SM, Crow MK.

Arthritis Rheum. 2007 Dec;56(12):3995-4004.

35.

T lymphocytes in Sjögren's syndrome: contributors to and regulators of pathophysiology.

Katsifis GE, Moutsopoulos NM, Wahl SM.

Clin Rev Allergy Immunol. 2007 Jun;32(3):252-64. Review.

PMID:
17992592
36.

Tonsil epithelial factors may influence oropharyngeal human immunodeficiency virus transmission.

Moutsopoulos NM, Nares S, Nikitakis N, Rangel Z, Wen J, Munson P, Sauk J, Wahl SM.

Am J Pathol. 2007 Aug;171(2):571-9. Epub 2007 Jul 9.

37.

Low-grade inflammation in chronic infectious diseases: paradigm of periodontal infections.

Moutsopoulos NM, Madianos PN.

Ann N Y Acad Sci. 2006 Nov;1088:251-64. Review.

PMID:
17192571
38.

Regulation of the tonsil cytokine milieu favors HIV susceptibility.

Moutsopoulos NM, Vázquez N, Greenwell-Wild T, Ecevit I, Horn J, Orenstein J, Wahl SM.

J Leukoc Biol. 2006 Nov;80(5):1145-55. Epub 2006 Aug 30.

PMID:
16943383
39.

The management of Sjögren's syndrome.

Mavragani CP, Moutsopoulos NM, Moutsopoulos HM.

Nat Clin Pract Rheumatol. 2006 May;2(5):252-61. Review.

PMID:
16932698
40.

Differential mucosal susceptibility in HIV-1 transmission and infection.

Moutsopoulos NM, Greenwell-Wild T, Wahl SM.

Adv Dent Res. 2006 Apr 1;19(1):52-6. Review.

PMID:
16672550
41.

Wound healing: immunological aspects.

Tsirogianni AK, Moutsopoulos NM, Moutsopoulos HM.

Injury. 2006 Apr;37 Suppl 1:S5-12. Epub 2006 Apr 17. Review.

PMID:
16616753
42.

The kiss of death: interrupted by NK-cell close encounters of another kind.

Wahl SM, Wen J, Moutsopoulos NM.

Trends Immunol. 2006 Apr;27(4):161-4. Epub 2006 Feb 28. Review.

PMID:
16504582
43.

Immunological consequences of thalidomide treatment in Sjögren's syndrome.

Moutsopoulos NM, Angelov N, Sankar V, Leakan RA, Pillemer S, Wahl SM.

Ann Rheum Dis. 2006 Jan;65(1):112-4.

44.

Carcinosarcoma of the maxilla in a squirrel monkey (Saimiri sciureus).

Moutsopoulos NM, Nikitakis NG, Powell DA, Reynolds MA.

Comp Med. 2004 Jun;54(3):333-6.

PMID:
15253282
45.

Therapy of Sjögren's syndrome.

Moutsopoulos NM, Moutsopoulos HM.

Springer Semin Immunopathol. 2001;23(1-2):131-45. Review. No abstract available.

PMID:
11455852
46.

B-cell epitopes of intracellular autoantigens: myth and reality.

Moutsopoulos NM, Routsias JG, Vlachoyiannopoulos PG, Tzioufas AG, Moutsopoulos HM.

Mol Med. 2000 Mar;6(3):141-51. Review. No abstract available. Erratum in: Mol Med 2000 Dec;6(12):1063.

47.

[Effectiveness and safety of using cyclosporin A in the treatment of primary Sjögren's syndrome].

Drosos AA, Moutsopoulos NM.

Ter Arkh. 1988;60(4):77-80. Russian.

PMID:
3293257
48.

[Monoclonal cryoglobulins in primary Sjögren's syndrome].

Tzioufas AG, Papadopoulos NM, Moutsopoulos NM.

Ter Arkh. 1988;60(4):25-7. Russian.

PMID:
3260691

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