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Correction to: Re-challenge of afatinib after 1st generation EGFR-TKI failure in patients with previously treated non-small cell lung cancer harboring EGFR mutation.

Yamaguchi O, Kaira K, Mouri A, Shiono A, Hashimoto K, Miura Y, Nishihara F, Murayama Y, Kobayashi K, Kagamu H.

Cancer Chemother Pharmacol. 2019 Nov 8. doi: 10.1007/s00280-019-03984-2. [Epub ahead of print]


Indoleamine 2,3-dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma.

Yamasuge W, Yamamoto Y, Fujigaki H, Hoshi M, Nakamoto K, Kunisawa K, Mouri A, Nabeshima T, Saito K.

Cancer Sci. 2019 Oct;110(10):3061-3067. doi: 10.1111/cas.14179. Epub 2019 Sep 25.


Clinical difference between discontinuation and retreatment with nivolumab after immune-related adverse events in patients with lung cancer.

Mouri A, Kaira K, Yamaguchi O, Shiono A, Miura Y, Hashimoto K, Nishihara F, Murayama Y, Kobayashi K, Kagamu H.

Cancer Chemother Pharmacol. 2019 Oct;84(4):873-880. doi: 10.1007/s00280-019-03926-y. Epub 2019 Aug 23.


Retrospective Prognostic Study of Death at Home or Hospice Versus at a Hospital Among Patients With Advanced Non-Small Cell Lung Cancer.

Hamamoto Y, Ibe T, Kodama H, Mouri A, Mineshita M.

Am J Hosp Palliat Care. 2019 Jul 31:1049909119865865. doi: 10.1177/1049909119865865. [Epub ahead of print]


Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues.

Yoshida Y, Fujigaki H, Kato K, Yamazaki K, Fujigaki S, Kunisawa K, Yamamoto Y, Mouri A, Oda A, Nabeshima T, Saito K.

Sci Rep. 2019 Jul 15;9(1):10243. doi: 10.1038/s41598-019-46666-y.


Chronic unpredictable mild stress-induced behavioral changes are coupled with dopaminergic hyperfunction and serotonergic hypofunction in mouse models of depression.

Lu Q, Mouri A, Yang Y, Kunisawa K, Teshigawara T, Hirakawa M, Mori Y, Yamamoto Y, Libo Z, Nabeshima T, Saito K.

Behav Brain Res. 2019 Oct 17;372:112053. doi: 10.1016/j.bbr.2019.112053. Epub 2019 Jul 6.


Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms.

Teshigawara T, Mouri A, Kubo H, Nakamura Y, Shiino T, Okada T, Morikawa M, Nabeshima T, Ozaki N, Yamamoto Y, Saito K.

J Affect Disord. 2019 Aug 1;255:168-176. doi: 10.1016/j.jad.2019.05.028. Epub 2019 May 17.


Radiotherapy is an independent prognostic marker of favorable prognosis in non-small cell lung cancer patients after treatment with the immune checkpoint inhibitor, nivolumab.

Yamaguchi O, Kaira K, Hashimoto K, Mouri A, Miura Y, Shiono A, Nishihara F, Murayama Y, Noda SE, Kato S, Kobayashi K, Kagamu H.

Thorac Cancer. 2019 Apr;10(4):992-1000. doi: 10.1111/1759-7714.13044. Epub 2019 Mar 19.


Different incidence of interstitial lung disease according to different kinds of EGFR-tyrosine kinase inhibitors administered immediately before and/or after anti-PD-1 antibodies in lung cancer.

Uchida T, Kaira K, Yamaguchi O, Mouri A, Shiono A, Miura Y, Hashimoto K, Nishihara F, Murayama Y, Kobayashi K, Kagamu H.

Thorac Cancer. 2019 Apr;10(4):975-979. doi: 10.1111/1759-7714.13039. Epub 2019 Mar 12.


Clinical significance of primary prophylactic pegylated-granulocyte-colony stimulating factor after the administration of ramucirumab plus docetaxel in patients with previously treated non-small cell lung cancer.

Mouri A, Kaira K, Shiono A, Yamaguchi O, Murayama Y, Kobayashi K, Kagamu H.

Thorac Cancer. 2019 Apr;10(4):1005-1008. doi: 10.1111/1759-7714.13022. Epub 2019 Mar 11.


Improved efficacy of ramucirumab plus docetaxel after nivolumab failure in previously treated non-small cell lung cancer patients.

Shiono A, Kaira K, Mouri A, Yamaguchi O, Hashimoto K, Uchida T, Miura Y, Nishihara F, Murayama Y, Kobayashi K, Kagamu H.

Thorac Cancer. 2019 Apr;10(4):775-781. doi: 10.1111/1759-7714.12998. Epub 2019 Feb 27.


Re-challenge of afatinib after 1st generation EGFR-TKI failure in patients with previously treated non-small cell lung cancer harboring EGFR mutation.

Yamaguchi O, Kaira K, Mouri A, Shiono A, Hashimoto K, Miura Y, Nishihara F, Murayama Y, Kobayashi K, Kagamu H.

Cancer Chemother Pharmacol. 2019 May;83(5):817-825. doi: 10.1007/s00280-019-03790-w. Epub 2019 Feb 13. Erratum in: Cancer Chemother Pharmacol. 2019 Nov 8;:.


Linking phencyclidine intoxication to the tryptophan-kynurenine pathway: Therapeutic implications for schizophrenia.

Fujigaki H, Mouri A, Yamamoto Y, Nabeshima T, Saito K.

Neurochem Int. 2019 May;125:1-6. doi: 10.1016/j.neuint.2019.02.001. Epub 2019 Feb 5. Review.


Acute administration of ketamine attenuates the impairment of social behaviors induced by social defeat stress exposure as juveniles via activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors.

Hasegawa S, Yoshimi A, Mouri A, Uchida Y, Hida H, Mishina M, Yamada K, Ozaki N, Nabeshima T, Noda Y.

Neuropharmacology. 2019 Apr;148:107-116. doi: 10.1016/j.neuropharm.2018.12.020. Epub 2018 Dec 24.


Combination therapy with carboplatin and paclitaxel for small cell lung cancer.

Mouri A, Yamaguchi O, Miyauchi S, Shiono A, Utsugi H, Nishihara F, Murayama Y, Kagamu H, Kobayashi K.

Respir Investig. 2019 Jan;57(1):34-39. doi: 10.1016/j.resinv.2018.09.004. Epub 2018 Oct 24.


Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through the regulation of IL-6/stat3 signalling.

Yamamoto Y, Yamasuge W, Imai S, Kunisawa K, Hoshi M, Fujigaki H, Mouri A, Nabeshima T, Saito K.

Sci Rep. 2018 Oct 29;8(1):15917. doi: 10.1038/s41598-018-34166-4.


5-HT1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox.

Tran HQ, Shin EJ, Hoai Nguyen BC, Phan DH, Kang MJ, Jang CG, Jeong JH, Nah SY, Mouri A, Saito K, Nabeshima T, Kim HC.

Food Chem Toxicol. 2019 Jan;123:125-141. doi: 10.1016/j.fct.2018.10.049. Epub 2018 Oct 24.


Influence of oral care on fractional exhaled nitric oxide.

Kamimura M, Ibe T, Fukusumi M, Mouri A, Hamamoto Y.

Asia Pac Allergy. 2018 Jul 4;8(3):e23. doi: 10.5415/apallergy.2018.8.e23. eCollection 2018 Jul.


Dysfunction of Serotonergic and Dopaminergic Neuronal Systems in the Antidepressant-Resistant Impairment of Social Behaviors Induced by Social Defeat Stress Exposure as Juveniles.

Hasegawa S, Miyake Y, Yoshimi A, Mouri A, Hida H, Yamada K, Ozaki N, Nabeshima T, Noda Y.

Int J Neuropsychopharmacol. 2018 Sep 1;21(9):837-846. doi: 10.1093/ijnp/pyy038.


Cerebellar α6 -subunit-containing GABAA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders.

Chiou LC, Lee HJ, Ernst M, Huang WJ, Chou JF, Chen HL, Mouri A, Chen LC, Treven M, Mamiya T, Fan PC, Knutson DE, Witzigmann C, Cook J, Sieghart W, Nabeshima T.

Br J Pharmacol. 2018 Jun;175(12):2414-2427. doi: 10.1111/bph.14198. Epub 2018 May 10.


PKCδ Knockout Mice Are Protected from Dextromethorphan-Induced Serotonergic Behaviors in Mice: Involvements of Downregulation of 5-HT1A Receptor and Upregulation of Nrf2-Dependent GSH Synthesis.

Tran HQ, Lee Y, Shin EJ, Jang CG, Jeong JH, Mouri A, Saito K, Nabeshima T, Kim HC.

Mol Neurobiol. 2018 Oct;55(10):7802-7821. doi: 10.1007/s12035-018-0938-7. Epub 2018 Feb 22.


Excess maternal fructose consumption impairs hippocampal function in offspring via epigenetic modification of BDNF promoter.

Yamazaki M, Yamada H, Munetsuna E, Ishikawa H, Mizuno G, Mukuda T, Mouri A, Nabeshima T, Saito K, Suzuki K, Hashimoto S, Ohashi K.

FASEB J. 2018 May;32(5):2549-2562. doi: 10.1096/fj.201700783RR. Epub 2018 Jan 8.


Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes.

Sobue A, Ito N, Nagai T, Shan W, Hada K, Nakajima A, Murakami Y, Mouri A, Yamamoto Y, Nabeshima T, Saito K, Yamada K.

Glia. 2018 May;66(5):1034-1052. doi: 10.1002/glia.23299. Epub 2018 Jan 30.


Juvenile social defeat stress exposure persistently impairs social behaviors and neurogenesis.

Mouri A, Ukai M, Uchida M, Hasegawa S, Taniguchi M, Ito T, Hida H, Yoshimi A, Yamada K, Kunimoto S, Ozaki N, Nabeshima T, Noda Y.

Neuropharmacology. 2018 May 1;133:23-37. doi: 10.1016/j.neuropharm.2018.01.016. Epub 2018 Jan 11.


Human neutrophils show decreased survival upon long-term exposure to clozapine.

Goto A, Yoshimi A, Nagai T, Ukigai M, Mouri A, Ozaki N, Noda Y.

Hum Psychopharmacol. 2017 Nov;32(6). doi: 10.1002/hup.2629. Epub 2017 Sep 15.


Adolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable mice.

Matsumoto Y, Niwa M, Mouri A, Noda Y, Fukushima T, Ozaki N, Nabeshima T.

Psychopharmacology (Berl). 2017 Oct;234(20):3055-3074. doi: 10.1007/s00213-017-4704-8. Epub 2017 Jul 29.


A new method for enhanced expectoration of sputum by vibratory stimulation of the cervical trachea.

Kamimura M, Kameyama N, Homma C, Ibe T, Takeoka S, Mouri A, Hamamoto Y.

Respir Investig. 2017 Jul;55(4):276-282. doi: 10.1016/j.resinv.2016.12.006. Epub 2017 Jun 20.


The involvement of brain-derived neurotrophic factor in 3,4-methylenedioxymethamphetamine-induced place preference and behavioral sensitization.

Mouri A, Noda Y, Niwa M, Matsumoto Y, Mamiya T, Nitta A, Yamada K, Furukawa S, Iwamura T, Nabeshima T.

Behav Brain Res. 2017 Jun 30;329:157-165. doi: 10.1016/j.bbr.2017.04.052. Epub 2017 May 1.


Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice.

Kubo H, Hoshi M, Mouri A, Tashita C, Yamamoto Y, Nabeshima T, Saito K.

Immunol Lett. 2017 Jan;181:94-100. doi: 10.1016/j.imlet.2016.11.012. Epub 2016 Nov 24.


Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions.

Tashiro T, Murakami Y, Mouri A, Imamura Y, Nabeshima T, Yamamoto Y, Saito K.

Behav Brain Res. 2017 Jan 15;317:279-285. doi: 10.1016/j.bbr.2016.09.050. Epub 2016 Sep 28.


A phase II study of bevacizumab with carboplatin-pemetrexed in non-squamous non-small cell lung carcinoma patients with malignant pleural effusions: North East Japan Study Group Trial NEJ013A.

Usui K, Sugawara S, Nishitsuji M, Fujita Y, Inoue A, Mouri A, Watanabe H, Sakai H, Kinoshita I, Ohhara Y, Maemondo M, Kagamu H, Hagiwara K, Kobayashi K; North East Japan Study Group.

Lung Cancer. 2016 Sep;99:131-6. doi: 10.1016/j.lungcan.2016.07.003. Epub 2016 Jul 5.


Involvement of the histamine H4 receptor in clozapine-induced hematopoietic toxicity: Vulnerability under granulocytic differentiation of HL-60 cells.

Goto A, Mouri A, Nagai T, Yoshimi A, Ukigai M, Tsubai T, Hida H, Ozaki N, Noda Y.

Toxicol Appl Pharmacol. 2016 Sep 1;306:8-16. doi: 10.1016/j.taap.2016.06.028. Epub 2016 Jun 28.


Orotate phosphoribosyltransferase is overexpressed in malignant pleural mesothelioma: Dramatically responds one case in high OPRT expression.

Hamamoto Y, Takeoka S, Mouri A, Fukusumi M, Wakuda K, Ibe T, Honma C, Arimoto Y, Yamada K, Wagatsuma M, Tashiro A, Kamoshida S, Kamimura M.

Rare Dis. 2016 Apr 5;4(1):e1165909. doi: 10.1080/21675511.2016.1165909. eCollection 2016. Review.


The effects of daily bathing on symptoms of patients with bronchial asthma.

Kamimura M, Arimoto Y, Homma C, Takeoka S, Fukusumi M, Mouri A, Hamamoto Y.

Asia Pac Allergy. 2016 Apr;6(2):112-9. doi: 10.5415/apallergy.2016.6.2.112. Epub 2016 Apr 28.


Prenatal phencyclidine treatment induces behavioral deficits through impairment of GABAergic interneurons in the prefrontal cortex.

Toriumi K, Oki M, Muto E, Tanaka J, Mouri A, Mamiya T, Kim HC, Nabeshima T.

Psychopharmacology (Berl). 2016 Jun;233(12):2373-81. doi: 10.1007/s00213-016-4288-8. Epub 2016 Apr 20.


Bronchoscopy for Pulmonary Peripheral Lesions With Virtual Fluoroscopic Preprocedural Planning Combined With EBUS-GS: A Pilot Study.

Fukusumi M, Ichinose Y, Arimoto Y, Takeoka S, Homma C, Matsuoka H, Mouri A, Hamamoto Y, Matsumoto J, Kamimura M.

J Bronchology Interv Pulmonol. 2016 Apr;23(2):92-7. doi: 10.1097/LBR.0000000000000273.


The ubiquitination of serotonin transporter in lymphoblasts derived from fluvoxamine-resistant depression patients.

Mouri A, Ikeda M, Koseki T, Iwata N, Nabeshima T.

Neurosci Lett. 2016 Mar 23;617:22-6. doi: 10.1016/j.neulet.2016.01.064. Epub 2016 Feb 1.


Formulation, physicochemical characterization and stability study of lithium-loaded microemulsion system.

Mouri A, Legrand P, El Ghzaoui A, Dorandeu C, Maurel JC, Devoisselle JM.

Int J Pharm. 2016 Apr 11;502(1-2):117-24. doi: 10.1016/j.ijpharm.2016.01.072. Epub 2016 Feb 4.


[An Elderly Patient with Non-Small Cell Lung Cancer Who Responded to Salvage S-1 Monotherapy after Gefitinib Therapy].

Mouri A, Hamamoto Y, Kameyama N, Ibe T, Takeoka S, Honma C, Fukusumi M, Kamimura M.

Gan To Kagaku Ryoho. 2015 Sep;42(9):1091-3. Japanese.


Arachidonic or Docosahexaenoic Acid Diet Prevents Memory Impairment in Tg2576 Mice.

Hosono T, Mouri A, Nishitsuji K, Jung CG, Kontani M, Tokuda H, Kawashima H, Shibata H, Suzuki T, Nabehsima T, Michikawa M.

J Alzheimers Dis. 2015;48(1):149-62. doi: 10.3233/JAD-150341.


Deletion of SHATI/NAT8L decreases the N-acetylaspartate content in the brain and induces behavioral deficits, which can be ameliorated by administering N-acetylaspartate.

Toriumi K, Mamiya T, Song Z, Honjo T, Watanabe H, Tanaka J, Kondo M, Mouri A, Kim HC, Nitta A, Fukushima T, Nabeshima T.

Eur Neuropsychopharmacol. 2015 Nov;25(11):2108-17. doi: 10.1016/j.euroneuro.2015.08.003. Epub 2015 Aug 12.


Development of pharmaceutical clear gel based on Peceol®, lecithin, ethanol and water: Physicochemical characterization and stability study.

Mouri A, Diat O, El Ghzaoui A, Ly I, Dorandeu C, Maurel JC, Devoisselle JM, Legrand P.

J Colloid Interface Sci. 2015 Nov 1;457:152-61. doi: 10.1016/j.jcis.2015.06.010. Epub 2015 Jun 17.


Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex.

Aoyama Y, Toriumi K, Mouri A, Hattori T, Ueda E, Shimato A, Sakakibara N, Soh Y, Mamiya T, Nagai T, Kim HC, Hiramatsu M, Nabeshima T, Yamada K.

Neuropsychopharmacology. 2016 Jan;41(2):578-89. doi: 10.1038/npp.2015.186. Epub 2015 Jun 24.


[Practical program to gather patient information from a diversified perspective and provide appropriate therapies in practical hospital training].

Tsubai T, Noda Y, Hibi Y, Mouri A, Nishikawa S, Yamada K, Nakao M.

Yakugaku Zasshi. 2015;135(3):507-18. doi: 10.1248/yakushi.14-00212. Japanese.


Respiratory failure associated with hypoventilation in a patient with severe hypothyroidism.

Fukusumi M, Iidaka T, Mouri A, Hamamoto Y, Kamimura M.

Respirol Case Rep. 2014 Jun;2(2):79-80. doi: 10.1002/rcr2.55. Epub 2014 Mar 13.


Behavioral characterization of mice overexpressing human dysbindin-1.

Shintani N, Onaka Y, Hashimoto R, Takamura H, Nagata T, Umeda-Yano S, Mouri A, Mamiya T, Haba R, Matsuzaki S, Katayama T, Yamamori H, Nakazawa T, Nagayasu K, Ago Y, Yagasaki Y, Nabeshima T, Takeda M, Hashimoto H.

Mol Brain. 2014 Oct 9;7:74. doi: 10.1186/s13041-014-0074-x.


Blonanserin ameliorates phencyclidine-induced visual-recognition memory deficits: the complex mechanism of blonanserin action involving D₃-5-HT₂A and D₁-NMDA receptors in the mPFC.

Hida H, Mouri A, Mori K, Matsumoto Y, Seki T, Taniguchi M, Yamada K, Iwamoto K, Ozaki N, Nabeshima T, Noda Y.

Neuropsychopharmacology. 2015 Feb;40(3):601-13. doi: 10.1038/npp.2014.207. Epub 2014 Aug 14.


Water solubilization capacity of pharmaceutical microemulsions based on Peceol®, lecithin and ethanol.

Mouri A, Diat O, Lerner DA, El Ghzaoui A, Ajovalasit A, Dorandeu C, Maurel JC, Devoisselle JM, Legrand P.

Int J Pharm. 2014 Nov 20;475(1-2):324-34. doi: 10.1016/j.ijpharm.2014.07.018. Epub 2014 Jul 15.


Thyrotoropin receptor knockout changes monoaminergic neuronal system and produces methylphenidate-sensitive emotional and cognitive dysfunction.

Mouri A, Hoshino Y, Narusawa S, Ikegami K, Mizoguchi H, Murata Y, Yoshimura T, Nabeshima T.

Psychoneuroendocrinology. 2014 Oct;48:147-61. doi: 10.1016/j.psyneuen.2014.05.021. Epub 2014 Jun 24.


Novel rare variants in F-box protein 45 (FBXO45) in schizophrenia.

Wang C, Koide T, Kimura H, Kunimoto S, Yoshimi A, Nakamura Y, Kushima I, Banno M, Kawano N, Takasaki Y, Xing J, Noda Y, Mouri A, Aleksic B, Ikeda M, Okada T, Iidaka T, Inada T, Iwata N, Ozaki N.

Schizophr Res. 2014 Aug;157(1-3):149-56. doi: 10.1016/j.schres.2014.04.032. Epub 2014 May 28.


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